Opportunity Information: Apply for RFA EB 09 003

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIBIB Quantum Projects Implementation Phase II (U01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health.
  • This funding opportunity was created on Nov 12, 2009 and posted on Nov 12, 2009.
  • Applicants must submit their applications by Jan 22, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $8,000,000.00 to eligible and selected applicants.
  • Eligible applicants include: For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Public and State controlled institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) .
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Opportunity Summary:

The NIBIB Quantum Projects Implementation Phase II (U01) funding opportunity (RFA-EB-09-003) is a National Institutes of Health grant solicitation issued by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) for the second phase of its Quantum Program. The central aim is to support ambitious biomedical technology efforts that can produce a truly substantial, step-change level of impact on a major disease area or a nationally significant public health problem. In practical terms, NIBIB is looking for projects where the technology development and implementation are expected to move the needle in prevention, diagnosis, or treatment in a way that is meaningfully beyond incremental improvement.

This announcement uses the U01 Research Project Cooperative Agreement mechanism. A U01 is distinct from a standard research project grant because it involves cooperative agreement features, meaning the NIH program staff typically has a more active role in coordination, oversight, and partnership during the life of the award than under a traditional R01. For applicants, that generally signals an expectation of clear milestones, active project management, and ongoing engagement with the funding institute as the work progresses through implementation-oriented objectives.

NIBIB indicated an anticipated program commitment of up to $8,000,000 in fiscal year 2010, with an expectation of making between one and three awards. That range implies the institute planned to concentrate resources into a small number of larger, high-impact projects rather than spreading funds broadly. As with many federal funding announcements, the actual awards were explicitly contingent on the availability of appropriated funds and the submission of enough highly competitive applications.

The opportunity falls under the discretionary grant category and is tied to CFDA number 93.286, described as Discovery and Applied Research for Technological Innovations to Improve Human Health. There is no cost sharing or matching requirement stated, which means applicants were not required to commit non-federal funds as a condition of receiving the award.

Eligibility was broad and included for-profit organizations (including those other than small businesses), small businesses, public and state-controlled institutions of higher education, private institutions of higher education, and multiple categories of nonprofit organizations (including both 501(c)(3) and certain non-501(c)(3) nonprofits outside higher education). The eligible applicant pool also explicitly included federally recognized Native American tribal governments and a set of institution types often highlighted in NIH eligibility language, such as Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and eligible agencies of the federal government. The listing also referenced an "Others" category with further clarification in the full announcement text, indicating that additional eligible entities may have been described in the complete FOA.

Key dates associated with the posting show it was published on November 12, 2009, with an application closing date of January 22, 2010, and an archive date of February 22, 2010. The full announcement was hosted through the NIH grants policy and funding opportunity pages, and technical access issues were directed to the NIH Office of Extramural Research (OER) webmaster contacts.

FAQs: NIBIB Quantum Projects Implementation Phase II (U01) - RFA-EB-09-003

What is this funding opportunity?

This is the NIBIB Quantum Projects Implementation Phase II (U01) funding opportunity (RFA-EB-09-003), a National Institutes of Health (NIH) grant solicitation issued by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) for the second phase of its Quantum Program.

What is the central aim of the program?

The central aim is to support ambitious biomedical technology efforts expected to produce a truly substantial, step-change level of impact on a major disease area or a nationally significant public health problem. The emphasis is on moving the needle in prevention, diagnosis, or treatment in a way that goes meaningfully beyond incremental improvement.

What types of outcomes is NIBIB looking for?

NIBIB is looking for technology development and implementation projects that are implementation-oriented and expected to deliver major improvements in prevention, diagnosis, or treatment, rather than modest or incremental advances.

What funding mechanism does this opportunity use?

This announcement uses the U01 Research Project Cooperative Agreement mechanism.

How is a U01 different from an R01?

A U01 is a cooperative agreement, which typically means NIH program staff have a more active role in coordination, oversight, and partnership during the life of the award than is typical under a traditional R01 research project grant.

What does the cooperative agreement structure imply for awardees?

It generally signals expectations such as clear milestones, active project management, and ongoing engagement with the funding institute (NIBIB) as the project progresses through implementation-focused objectives.

How much funding was NIBIB planning to commit?

NIBIB indicated an anticipated program commitment of up to $8,000,000 in fiscal year (FY) 2010.

How many awards were expected?

NIBIB expected to make between one and three awards.

What does the small expected number of awards suggest?

It suggests NIBIB planned to concentrate resources into a small number of larger, high-impact projects rather than distributing funds broadly across many smaller awards.

Were awards guaranteed?

No. The announcement stated that actual awards were contingent on the availability of appropriated funds and on receiving a sufficient number of highly competitive applications.

What grant category does this opportunity fall under?

The opportunity falls under the discretionary grant category.

What is the CFDA number and program name associated with this opportunity?

The opportunity is tied to CFDA number 93.286, described as "Discovery and Applied Research for Technological Innovations to Improve Human Health."

Is cost sharing or matching required?

No cost sharing or matching requirement was stated. Based on the provided information, applicants were not required to commit non-federal funds as a condition of receiving the award.

Who was eligible to apply?

Eligibility was broad and included for-profit organizations (including those other than small businesses), small businesses, public and state-controlled institutions of higher education, private institutions of higher education, and multiple categories of nonprofit organizations (including both 501(c)(3) and certain non-501(c)(3) nonprofits outside higher education).

Are tribal governments eligible?

Yes. Federally recognized Native American tribal governments were explicitly included as eligible applicants.

Are minority-serving institutions mentioned as eligible?

Yes. The eligible applicant pool explicitly included institution types commonly highlighted in NIH eligibility language, including Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and similar categories referenced in the opportunity description.

Are federal agencies eligible to apply?

Yes. Eligible agencies of the federal government were listed as eligible applicants.

What does the "Others" eligibility category mean?

The eligibility listing referenced an "Others" category with further clarification in the full announcement text, indicating that additional eligible entities may have been described in the complete Funding Opportunity Announcement (FOA).

When was the opportunity posted?

The posting date was November 12, 2009.

What was the application closing date?

The application closing date was January 22, 2010.

When was the opportunity archived?

The archive date was February 22, 2010.

Where was the full announcement hosted?

The full announcement was hosted through NIH grants policy and funding opportunity pages.

Where were applicants directed for technical access issues?

Technical access issues were directed to the NIH Office of Extramural Research (OER) webmaster contacts.

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