Opportunity Information: Apply for PAR 16 009

  • The HHS-NIH11 in the education, health sector is offering a public funding opportunity titled "NIDA Research Center of Excellence Grant Program (P50)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279,.
  • This funding opportunity was created on Oct 21, 2015 and posted on Oct 21, 2015.
  • Applicants must submit their applications by Jan 07, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for PAR 16 009

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Opportunity Summary:

The NIDA Research Center of Excellence Grant Program (P50) is a National Institutes of Health funding opportunity designed to support large, high-impact research centers focused on drug abuse and addiction. The intent is to fund centers that pursue research aligned with the mission of the National Institute on Drug Abuse (NIDA) and that aim to move the field forward in meaningful, non-incremental ways. These centers are expected to pursue outstanding, innovative science that can transform understanding in the specific areas they study, rather than simply extending existing work in small steps. A core theme of the program is that funded centers should take creative, new directions and generate influential advances that reshape knowledge, methods, or practice in drug abuse and addiction research.

A defining feature of this P50 program is the expectation of multidisciplinary, thematically integrated work. In practical terms, this means the center should bring together investigators and approaches from multiple disciplines and align them around a unifying theme or set of scientific questions, with projects designed to be synergistic rather than isolated. The funded center is meant to function as an integrated enterprise where the whole is stronger than the sum of its parts, often through shared cores, coordinated research projects, collaborative workflows, and common data or resources that accelerate discovery across the center.

Beyond producing research findings, the program emphasizes that each center should serve as a national resource. This includes active educational and outreach activities aimed at multiple audiences such as drug abuse research communities, educational organizations, the general public, and policy makers working in or affected by NIDA-related fields. The expectation is that the center will not only generate knowledge but also help translate and disseminate that knowledge through training events, public-facing education, stakeholder engagement, and other outreach mechanisms that broaden impact and strengthen the national research and policy ecosystem.

Career development is another explicit goal of the P50 Center of Excellence model. The FOA highlights the importance of fostering the professional growth of new investigators by providing mentoring and giving them meaningful roles within center projects. Rather than being peripheral participants, early-stage or emerging researchers are expected to be integrated into the center’s scientific activities in ways that build independence, expand expertise, and cultivate the next generation of leaders in drug abuse and addiction research.

A further program objective is open science and community benefit through sharing. NIDA’s goal is to create centers that function as community resources by sharing research findings, data, and other resources as appropriate so other researchers can use them, build upon them, and accelerate progress across the field. This positions the center not just as a research producer but as an infrastructure hub that helps strengthen collaboration, reproducibility, and cumulative advancement in drug abuse research.

Administratively, this opportunity is issued by the U.S. Department of Health and Human Services through NIH (agency listed as HHS-NIH11). The funding opportunity title is "NIDA Research Center of Excellence Grant Program (P50)" and the funding opportunity number is PAR-16-009. It is a discretionary grant program categorized under Education and Health, with CFDA numbers 93.279. The announcement was posted on October 21, 2015, and lists a closing date of January 7, 2019. Eligibility is broad and includes various levels of government (state, county, city/township, special districts), tribal governments and tribal organizations, public and private institutions of higher education, independent school districts, public housing/Indian housing authorities, nonprofits with and without 501(c)(3) status, for-profit organizations (other than small businesses), small businesses, and other eligible entities as described in the full FOA. The source data provided does not specify an award ceiling or the expected number of awards.

Frequently Asked Questions (FAQs)

What is the NIDA Research Center of Excellence Grant Program (P50)?

The NIDA Research Center of Excellence Grant Program (P50) is a National Institutes of Health (NIH) funding opportunity designed to support large, high-impact research centers focused on drug abuse and addiction. It supports centers pursuing research aligned with the mission of the National Institute on Drug Abuse (NIDA).

What is the main purpose of this funding opportunity?

The main purpose is to fund research centers that move the field forward in meaningful, non-incremental ways. The program emphasizes outstanding, innovative science that can transform understanding in specific areas of drug abuse and addiction research, rather than modest extensions of existing work.

What kind of research is this program trying to support?

This program is intended to support creative, new directions in drug abuse and addiction research that generate influential advances and reshape knowledge, methods, or practice. The focus is on high-impact center-based work rather than isolated projects.

What does "non-incremental" progress mean in the context of this program?

In this context, non-incremental progress means the center is expected to pursue research that significantly advances the field, rather than making small, step-by-step additions to existing lines of work. The goal is transformative impact.

What is a defining feature of the P50 Center of Excellence model described here?

A defining feature is multidisciplinary, thematically integrated work. The center should bring together investigators and approaches from multiple disciplines and align them around a unifying theme or set of scientific questions.

What does "multidisciplinary, thematically integrated" mean for a proposed center?

It means multiple disciplines are intentionally coordinated around a shared theme, and the center's projects are designed to be synergistic rather than separate or unrelated. The center should operate as an integrated enterprise where coordinated projects and shared resources strengthen overall impact.

How are projects expected to work together within the center?

Projects are expected to be synergistic, meaning they should complement and reinforce each other rather than operate as independent efforts. The center is intended to function so that the whole is stronger than the sum of its parts.

Are shared cores or shared resources part of the expected center structure?

Yes. The description notes that integrated centers often rely on shared cores, coordinated research projects, collaborative workflows, and common data or resources that accelerate discovery across the center.

Is the center expected to do more than publish research findings?

Yes. Beyond research findings, each center is expected to serve as a national resource through educational and outreach activities aimed at multiple audiences, including the research community, educational organizations, the general public, and policy makers.

Who are the intended audiences for education and outreach activities?

Intended audiences include drug abuse research communities, educational organizations, the general public, and policy makers working in or affected by NIDA-related fields.

What types of education and outreach activities are emphasized?

The opportunity highlights training events, public-facing education, stakeholder engagement, and other outreach mechanisms intended to translate and disseminate knowledge and broaden the center's impact.

Does this program include career development expectations?

Yes. Career development is described as an explicit goal of the P50 Center of Excellence model, with an emphasis on fostering the professional growth of new investigators through mentoring and meaningful roles within center projects.

How should early-stage or emerging researchers be involved?

They are expected to be integrated into the center's scientific activities in ways that build independence, expand expertise, and cultivate the next generation of leaders in drug abuse and addiction research, rather than being peripheral participants.

What is the program's position on open science and sharing?

The program emphasizes open science and community benefit through sharing. The goal is for centers to function as community resources by sharing research findings, data, and other resources as appropriate so other researchers can use and build upon them.

Why does the program emphasize sharing data and resources?

Sharing is positioned as a way to accelerate progress across the field by strengthening collaboration, reproducibility, and cumulative advancement in drug abuse research.

Who issues and administers this funding opportunity?

This opportunity is issued by the U.S. Department of Health and Human Services (HHS) through the National Institutes of Health (NIH), with the agency listed as HHS-NIH11.

What is the official title and funding opportunity number?

The official title is "NIDA Research Center of Excellence Grant Program (P50)" and the funding opportunity number is PAR-16-009.

What is the CFDA number for this program?

The CFDA number listed for this program is 93.279.

What type of grant program is this categorized as?

It is described as a discretionary grant program categorized under Education and Health.

When was the announcement posted?

The announcement was posted on October 21, 2015.

What is the closing date listed for this opportunity?

The closing date listed is January 7, 2019.

Who is eligible to apply based on the information provided?

Eligibility is described as broad and includes state, county, city/township, and special district governments; tribal governments and tribal organizations; public and private institutions of higher education; independent school districts; public housing/Indian housing authorities; nonprofits with and without 501(c)(3) status; for-profit organizations (other than small businesses); small businesses; and other eligible entities as described in the full FOA.

Are both public and private universities eligible?

Yes. Public and private institutions of higher education are listed as eligible entities.

Are nonprofits eligible even if they do not have 501(c)(3) status?

Yes. The eligibility list includes nonprofits with and without 501(c)(3) status.

Are for-profit organizations eligible?

Yes. For-profit organizations (other than small businesses) are listed, and small businesses are also listed separately as eligible.

Are government entities eligible to apply?

Yes. Multiple government entity types are listed as eligible, including state, county, city/township, and special district governments, as well as public housing/Indian housing authorities.

Are tribal governments and tribal organizations eligible?

Yes. Tribal governments and tribal organizations are explicitly included in the eligibility list.

Does the provided information specify an award ceiling?

No. The source data provided does not specify an award ceiling.

Does the provided information specify the expected number of awards?

No. The source data provided does not specify the expected number of awards.

What does it mean that the center should serve as a "national resource"?

Based on the description, serving as a national resource means going beyond producing research results by actively engaging in education and outreach and by disseminating knowledge to multiple audiences, including the public and policy makers, in addition to the research community.

What is the overall vision for how a funded center should operate?

The overall vision is an integrated, multidisciplinary center organized around a unifying theme, with synergistic projects, shared resources that accelerate discovery, active education and outreach efforts, meaningful career development for new investigators, and a commitment to sharing findings and resources to benefit the broader community.

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