Opportunity Information: Apply for PAR 10 047

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIDCD Clinical Research Center Grant (P50)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.173 Research Related to Deafness and Communication Disorders.
  • This funding opportunity was created on Dec 9, 2009 and posted on Dec 9, 2009.
  • Applicants must submit their applications by Oct 1, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $1,500,000.00 in funding.
  • Eligible applicants include: State governments For profit organizations other than small businesses Private institutions of higher education Small businesses Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education.
  • Other Eligible Applicants include the following Eligible Agencies of the Federal Government Regional Organizations U.S. Territory or Possession.
Apply for PAR 10 047

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Opportunity Summary:

The NIDCD Clinical Research Center Grant (P50), Funding Opportunity Number PAR-10-047, is a National Institutes of Health discretionary grant opportunity intended to strengthen and accelerate clinical research focused on human communication disorders. The central goal is to advance real-world progress in diagnosis, prevention, treatment, and overall reduction of the impact of disorders that affect how people hear, balance, smell, taste, speak, use their voice, and understand or produce language. While NIDCD notes that much of the work in its mission areas is typically supported through investigator-initiated awards such as R01, R21, R03, and R15, as well as research core center grants (P30), this announcement highlights that some clinical research situations are complex enough to justify the P50 center-style mechanism. In other words, the P50 is positioned for circumstances where a coordinated clinical research “center” structure can provide added value beyond what separate individual projects might achieve on their own.

For this opportunity, “clinical research” is defined broadly but clearly: it includes research that directly involves individuals with communication disorders, as well as research using data or tissues obtained from individuals who have a communication disorder. The scope of acceptable topics is wide within the NIDCD mission and explicitly includes studies addressing prevention, disease mechanisms (including pathogenesis and pathophysiology), diagnosis, treatment, management, and epidemiology. The eligible disease and disorder areas span hearing and balance disorders, disorders of smell and taste, and disorders involving voice, speech, and language. The emphasis is on clinically oriented work that can move the field toward better understanding and better care for affected individuals, whether that means identifying risk factors, improving diagnostic pathways, testing interventions, or developing better strategies for long-term management.

The funding mechanism is the NIH P50 grant, which is commonly used to support specialized centers that bring multiple components together under a single coordinated program. The announcement indicates that award size and project duration are expected to vary depending on what applicants propose, reflecting differences in scientific scope, clinical complexity, and required infrastructure. The stated award ceiling is $1,500,000, and there is no cost sharing or matching requirement. The NIH also notes that the total number of awards and total dollars ultimately committed will depend on the quality of applications received, their proposed timelines, and their budgets, rather than a fixed number of predetermined awards.

Eligibility is broad and includes public and private institutions of higher education, public and state-controlled institutions of higher education, nonprofit organizations (including both 501(c)(3) and non-501(c)(3) entities), state governments, small businesses, and for-profit organizations other than small businesses. Additional eligible applicants also include certain federal agencies, regional organizations, and U.S. territories or possessions, as referenced in the opportunity’s eligibility clarification. The program is listed under CFDA 93.173 (Research Related to Deafness and Communication Disorders). Key dates included in the posting show it was posted on December 9, 2009, with an original and current closing date of October 1, 2012, and an archive date of November 1, 2012.

Overall, PAR-10-047 describes a center-based clinical research grant meant for teams that can justify why a P50 structure is necessary to tackle clinically focused problems in communication disorders. It supports integrated, human-centered research efforts that may require coordinated clinical populations, shared resources, and structured collaboration to produce outcomes that meaningfully improve understanding, diagnosis, and treatment across the NIDCD mission areas.

FAQs: NIDCD Clinical Research Center Grant (P50) - PAR-10-047

What is the NIDCD Clinical Research Center Grant (P50) opportunity?

It is a National Institutes of Health (NIH) discretionary grant opportunity from the National Institute on Deafness and Other Communication Disorders (NIDCD) intended to strengthen and accelerate clinical research focused on human communication disorders. The funding opportunity number is PAR-10-047, and it uses the NIH P50 center grant mechanism.

What is the main goal of this grant?

The central goal is to advance real-world progress in the diagnosis, prevention, treatment, and overall reduction of the impact of disorders affecting hearing, balance, smell, taste, speech, voice, and language (including understanding or producing language).

Why does this opportunity use the P50 mechanism instead of typical NIH project grants?

NIDCD notes that much of its mission-related work is often supported through investigator-initiated awards (such as R01, R21, R03, and R15) and research core center grants (P30). This announcement highlights that some clinical research situations are complex enough to justify a coordinated clinical research “center” structure, where the P50 mechanism can add value beyond what separate individual projects might achieve on their own.

How does this opportunity define "clinical research"?

Clinical research is defined broadly but clearly. It includes research that directly involves individuals with communication disorders, as well as research using data or tissues obtained from individuals who have a communication disorder.

What types of research topics are allowed under this opportunity?

The scope is wide within the NIDCD mission and explicitly includes studies on prevention, disease mechanisms (including pathogenesis and pathophysiology), diagnosis, treatment, management, and epidemiology.

Which disorder areas are within scope for this grant?

Eligible areas span hearing and balance disorders, disorders of smell and taste, and disorders involving voice, speech, and language.

Is the program focused on basic science, clinical work, or both?

The emphasis is on clinically oriented work that can move the field toward better understanding and better care for affected individuals. The opportunity supports human-centered research efforts, including studies that use data or tissues from individuals with communication disorders.

What kinds of outcomes is NIDCD aiming to support through this center grant?

The announcement emphasizes outcomes that meaningfully improve understanding, diagnosis, and treatment across NIDCD mission areas. Examples of the kinds of progress described include identifying risk factors, improving diagnostic pathways, testing interventions, and developing better strategies for long-term management.

What is the funding mechanism for this opportunity?

The funding mechanism is the NIH P50 grant, which is commonly used to support specialized centers that bring multiple components together under a single coordinated program.

How much funding is available per award?

The stated award ceiling is $1,500,000. The announcement also notes that award size is expected to vary depending on what applicants propose.

How long can projects be funded?

Project duration is expected to vary depending on what applicants propose, reflecting differences in scientific scope, clinical complexity, and required infrastructure.

Is cost sharing or matching required?

No. The opportunity states there is no cost sharing or matching requirement.

How many awards will be made?

The total number of awards and the total dollars committed will depend on the quality of applications received, their proposed timelines, and their budgets. The opportunity does not state a fixed number of predetermined awards.

Who is eligible to apply?

Eligibility is broad and includes public and private institutions of higher education, public and state-controlled institutions of higher education, nonprofit organizations (including both 501(c)(3) and non-501(c)(3) entities), state governments, small businesses, and for-profit organizations other than small businesses.

Are any other types of applicants mentioned as eligible?

Yes. The opportunity also references additional eligible applicants including certain federal agencies, regional organizations, and U.S. territories or possessions (as described in the opportunity’s eligibility clarification).

What NIH program area or catalog listing is this opportunity associated with?

The program is listed under CFDA 93.173, titled "Research Related to Deafness and Communication Disorders."

What are the key dates for PAR-10-047?

The posting shows it was posted on December 9, 2009. The original and current closing date is October 1, 2012. The archive date is November 1, 2012.

Is this opportunity intended for single-project proposals or coordinated center programs?

It is intended for center-based clinical research programs where teams can justify why a P50 structure is necessary, particularly for clinically focused problems that benefit from coordinated clinical populations, shared resources, and structured collaboration.

Does the opportunity allow research that uses existing human data or human tissues?

Yes. The definition of clinical research includes research using data or tissues obtained from individuals who have a communication disorder.

What is the overall purpose of establishing a P50 clinical research center under this announcement?

Overall, PAR-10-047 describes a center-based clinical research grant meant to support integrated efforts that may require coordinated clinical populations, shared resources, and structured collaboration to accelerate progress in understanding, diagnosis, and treatment within NIDCD mission areas.

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