Opportunity Information: Apply for PAR 14 057

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIDCR Dentist Scientist Pathway to Independence Award (K99/R00)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121 Oral Diseases and Disorders Research.
  • This funding opportunity was created on Jan 2, 2014 and posted on Jan 2, 2014.
  • Applicants must submit their applications by Jan 7, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) County governments City or township governments State governments Independent school districts Public housing authorities/Indian housing authorities Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education Public and State controlled institutions of higher education For profit organizations other than small businesses Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:

The NIDCR Dentist Scientist Pathway to Independence Award (K99/R00), funding opportunity number PAR-14-057, is a National Institutes of Health grant program aimed at building and sustaining a strong pipeline of independent, dual degree dentist-scientists. Its central goal is to help exceptionally promising clinician-researchers move efficiently from mentored postdoctoral research roles into stable, independent faculty positions where they can run their own competitive research programs. In practical terms, this opportunity is structured as a transition award: it supports a defined period of mentored development followed by a longer period of independent research support, specifically tailored to help early-career dentist-scientists clear the major career hurdle between training and independence.

The award is split into two sequential phases. The first is the K99 mentored phase, which provides up to two years of support while the investigator remains in a postdoctoral or otherwise mentored research environment. This period is meant to strengthen research skills, deepen scientific focus, generate publishable results, and position the candidate to secure an independent, tenure-track (or equivalent) academic appointment. The second is the R00 independent phase, which provides three to five years of support once the investigator has successfully transitioned into an independent faculty role. The program’s design reflects the idea that talented dentist-scientists often need both time and protected resources to make this jump, especially when balancing clinical identity with the demands of establishing a research lab or research program.

A notable feature of this specific NIDCR pathway is the flexibility to extend the independent (R00) phase to as long as five years when needed to accommodate clinical specialty training, provided that the clinical training effort does not exceed 25 percent. This acknowledges a common reality for dentist-scientists: many pursue or complete specialty training while launching an academic research career, and that combination can slow early research momentum without structured support. By allowing an extended R00 window under defined effort limits, NIDCR is effectively trying to keep highly trained clinician-researchers from falling off the research track during a particularly demanding stage of professional development.

From an administrative and eligibility standpoint, the program is categorized as a discretionary grant under the NIH, within the health activity area, and is associated with CFDA number 93.121 (Oral Diseases and Disorders Research). The announcement states there is no cost sharing or matching requirement, which means applicants generally are not expected to commit non-federal matching funds as a condition of award. The opportunity was posted on January 2, 2014, with an original and current closing date listed as January 7, 2017, and an archive date of February 7, 2017, indicating that this specific announcement is no longer open even though it remains a reference point for the program’s structure and intent.

Eligible applicant organizations are broad and include many common U.S.-based research and training institutions and governmental entities. These include public and private institutions of higher education, public and state-controlled institutions of higher education, nonprofit organizations (including 501(c)(3) and non-501(c)(3) nonprofits), for-profit organizations other than small businesses, and small businesses, as well as various levels of government such as state, county, and city/township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities. The eligibility language also explicitly includes a range of mission-driven and minority-serving institution types, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American and Native American Pacific Islander Serving Institutions (AANAPISIs), along with faith-based or community-based organizations and U.S. territories or possessions.

At the same time, the announcement clearly restricts non-U.S. participation in key ways. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply, non-domestic components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed. In other words, the organizational applicant and the supported work are intended to remain within eligible U.S. institutional settings without foreign components under NIH definitions.

Overall, this funding opportunity is best understood as a career-launch mechanism specifically for dual degree dentist-scientists: it provides a structured, time-limited bridge from intensive mentorship to true independence, with the explicit expectation that awardees will emerge ready to compete as independent investigators in oral health and related biomedical research. The full announcement and official details were referenced through the NIH Grants Guide page linked in the notice (http://grants.nih.gov/grants/guide/pa-files/PAR-14-057.html), and the listed contact for technical access or linking problems was the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.

Frequently Asked Questions (FAQs)

What is the NIDCR Dentist Scientist Pathway to Independence Award (K99/R00)?

The NIDCR Dentist Scientist Pathway to Independence Award (K99/R00) is an NIH grant program intended to build and sustain a strong pipeline of independent, dual degree dentist-scientists. It is designed to help exceptionally promising clinician-researchers move from mentored postdoctoral research positions into stable, independent faculty roles where they can lead their own competitive research programs.

What is the funding opportunity number for this program?

The funding opportunity number is PAR-14-057.

What is the primary purpose of this award?

The central goal is to support early-career dentist-scientists through the major career transition between mentored training and research independence. The award provides structured support first for mentored career development and then for independent research once the investigator secures an independent faculty appointment.

How is the K99/R00 award structured?

This is a transition award with two sequential phases:

  • K99 mentored phase: up to 2 years of support in a mentored research environment.
  • R00 independent phase: 3 to 5 years of support after transitioning to an independent faculty role.

How long can the mentored K99 phase last?

The K99 mentored phase can provide up to two years of support while the investigator remains in a postdoctoral or otherwise mentored research setting.

How long can the independent R00 phase last?

The R00 independent phase can provide three to five years of support once the investigator has transitioned into an independent faculty position.

When can the R00 phase be extended to five years?

This NIDCR pathway includes flexibility to extend the R00 phase to as long as five years when needed to accommodate clinical specialty training, as long as the clinical training effort does not exceed 25 percent.

Does the program allow clinical specialty training during the R00 phase?

Yes. The opportunity notes that the R00 phase may be extended to accommodate clinical specialty training, provided the clinical training effort stays at or below 25 percent.

What career transition does this award support?

It supports the transition from a mentored postdoctoral (or otherwise mentored) research role into a stable, independent faculty position (tenure-track or equivalent) where the investigator can run an independent research program.

What is the program trying to achieve for awardees by the end of the transition?

The expectation described is that awardees will emerge ready to compete as independent investigators in oral health and related biomedical research, with the ability to lead their own competitive research programs.

Which NIH institute is associated with this opportunity?

The opportunity is associated with NIDCR (the National Institute of Dental and Craniofacial Research).

What is the CFDA number associated with this opportunity?

The CFDA number listed is 93.121 (Oral Diseases and Disorders Research).

What type of grant is this categorized as?

The program is categorized as a discretionary grant under the NIH within the health activity area.

Is cost sharing or matching required?

No. The announcement states there is no cost sharing or matching requirement, meaning applicants generally are not expected to provide non-federal matching funds as a condition of the award.

When was this opportunity posted?

The opportunity was posted on January 2, 2014.

What were the closing date and archive date listed for this announcement?

The original and current closing date listed was January 7, 2017, and the archive date was February 7, 2017.

Is this specific funding announcement still open?

No. Based on the listed closing and archive dates, this specific announcement (PAR-14-057) is no longer open, even though it remains useful as a reference for the program's structure and intent.

What types of organizations are eligible to apply?

The eligible applicant organizations are broad and include:

  • Public and private institutions of higher education
  • Public and state-controlled institutions of higher education
  • Nonprofit organizations (including 501(c)(3) and non-501(c)(3) nonprofits)
  • For-profit organizations other than small businesses
  • Small businesses
  • State, county, and city/township governments
  • Special district governments
  • Independent school districts
  • Public housing authorities/Indian housing authorities
  • U.S. territories or possessions
  • Faith-based or community-based organizations

Are minority-serving institutions included as eligible applicants?

Yes. The eligibility language explicitly includes a range of minority-serving institution types, including HBCUs, Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and AANAPISIs.

Are non-U.S. (foreign) organizations eligible to apply?

No. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply under this announcement.

Can non-U.S. components of U.S. organizations participate?

No. The announcement states that non-domestic components of U.S. organizations are not eligible.

Are foreign components allowed under NIH policy for this opportunity?

No. Foreign components (as defined by NIH policy) are not allowed under this announcement.

Where can the full official announcement be found?

The notice references the NIH Grants Guide page for PAR-14-057 at: http://grants.nih.gov/grants/guide/pa-files/PAR-14-057.html

Who is listed as the contact for technical access or linking problems?

The listed contact for technical access or linking problems is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.

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