Opportunity Information: Apply for PAR 12 283

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIDCR Dentist Scientist Pathway to Independence Award (K99/R00)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121 Oral Diseases and Disorders Research.
  • This funding opportunity was created on Jan 2, 2014 and posted on Sep 11, 2012.
  • Applicants must submit their applications by Jan 7, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $7,500,000.00 to eligible and selected applicants.
  • Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Small businesses City or township governments For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Public and State controlled institutions of higher education Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) State governments Special district governments Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:

The NIDCR Dentist Scientist Pathway to Independence Award (K99/R00) (Funding Opportunity Number PAR-12-283) is a discretionary NIH grant program in the health research area focused on oral diseases and disorders (CFDA 93.121). Its central goal is to strengthen the pipeline of dentist-scientists and other promising early-career researchers by helping them move more quickly from a mentored postdoctoral research setting into a stable, fully independent research position. In practical terms, the award is built to support a structured transition: an initial mentored phase (K99) that provides protected time, training, and career development while the candidate completes critical postdoctoral research, followed by an independent phase (R00) that supports the launch of an independent research program once the awardee secures an eligible faculty-level (or equivalent) independent position. The intent is to help talented investigators reach research independence earlier than has traditionally been typical, while also building a strong cohort of NIH-supported independent investigators over time.

This opportunity is administered by the National Institutes of Health, specifically aligned with the mission space of the National Institute of Dental and Craniofacial Research (NIDCR). As a grant mechanism, it is aimed at advancing investigator development rather than funding a single stand-alone project in isolation. The program is designed to provide a clear career trajectory: candidates are expected to use the mentored period to deepen scientific expertise, strengthen publication and preliminary data foundations, and develop the skills needed to compete successfully for independent NIH or other independent research support. The independent phase is meant to provide momentum and stability during the early years of running a research program, when establishing a laboratory, building collaborations, and generating competitive results for future major awards are especially challenging.

The eligibility framework is broad on the institutional side and includes many types of U.S.-based applicant organizations, such as public and private institutions of higher education, nonprofits (including 501(c)(3) and non-501(c)(3) entities), for-profit organizations (including small businesses and other for-profits), and various government entities (state, county, city or township, special district, and independent school districts), as well as eligible tribal organizations and tribal governments. The announcement also identifies additional eligible applicants including Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal agencies. A key restriction is that non-U.S. (foreign) institutions are not eligible to apply, and foreign components are not allowed under NIH policy as referenced in the opportunity language. Cost sharing or matching is not required, which generally lowers barriers for institutions and candidates by not requiring non-federal funds to be committed as a condition of the award.

From an administrative and historical standpoint, the opportunity was posted on September 11, 2012, with an estimated total funding level of $7,500,000. The record indicates an original closing date of September 7, 2015, with a listed current closing date of January 7, 2014, and an archive date of February 7, 2014, reflecting that this particular posting is now archived. Applicants seeking the full official requirements, budget structure, and application instructions were directed to the NIH Grants Guide link associated with the announcement (PAR-12-283). For access or technical issues, the contact listed is the NIH Office of Extramural Research (OER) webmaster (FBOWebmaster@OD.NIH.GOV), which suggests the primary support channel for difficulties retrieving or linking to the announcement materials.

Overall, the K99/R00 structure is meant to reduce the career bottleneck between postdoctoral training and independent faculty-level research by creating a predictable, milestone-driven pathway. The program’s emphasis is on accelerating independence while maintaining rigorous mentorship and preparation, ultimately expanding the number of well-trained, competitive, independently funded investigators contributing to NIH and NIDCR research priorities in oral health and related disorders.

FAQs: NIDCR Dentist Scientist Pathway to Independence Award (K99/R00) (PAR-12-283)

What is the NIDCR Dentist Scientist Pathway to Independence Award (K99/R00)?

It is a discretionary NIH grant program administered in the mission space of the National Institute of Dental and Craniofacial Research (NIDCR). The award is designed to help dentist-scientists and other promising early-career researchers move from a mentored postdoctoral research environment into a stable, fully independent research position through a structured transition mechanism (K99 to R00).

What is the Funding Opportunity Number for this program?

The Funding Opportunity Number is PAR-12-283.

What research area does this opportunity focus on?

The opportunity is in the health research area, focused on oral diseases and disorders, aligned with NIDCR priorities.

What CFDA number is associated with this opportunity?

The CFDA number listed is 93.121.

What is the main goal of the K99/R00 mechanism in this announcement?

The central goal is to strengthen the pipeline of dentist-scientists and other promising early-career researchers by enabling a faster transition from mentored postdoctoral training into an independent research position, helping investigators reach independence earlier than has traditionally been typical.

How is the award structured?

It has two phases: an initial mentored phase (K99) followed by an independent phase (R00). The design supports a structured transition from postdoctoral training to independent research leadership.

What is the purpose of the mentored K99 phase?

The mentored K99 phase is intended to provide protected time, training, and career development while the candidate completes critical postdoctoral research. During this period, candidates are expected to deepen scientific expertise, strengthen publications and preliminary data, and build the skills needed to compete for independent research support.

What is the purpose of the independent R00 phase?

The R00 phase supports the launch of an independent research program once the awardee secures an eligible independent position (faculty-level or equivalent). It is meant to provide momentum and stability during the early years of establishing a research program, including setting up a laboratory, building collaborations, and generating results that support future major awards.

Is this program intended to fund a single stand-alone research project?

Not primarily. The announcement describes it as an investigator development mechanism aimed at advancing career development and research independence rather than funding a project in isolation.

Who administers this opportunity?

The opportunity is administered by the National Institutes of Health (NIH), specifically aligned with NIDCR.

What types of U.S.-based organizations are eligible to apply?

The eligibility framework includes a wide range of U.S.-based applicant organizations, such as public and private institutions of higher education; nonprofit organizations (including 501(c)(3) and non-501(c)(3) entities); for-profit organizations (including small businesses and other for-profits); and government entities (state, county, city or township, special district, and independent school districts). It also includes eligible tribal organizations and tribal governments.

Are minority-serving and mission-specific institutions listed as eligible applicants?

Yes. The announcement identifies additional eligible applicants including Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs), as well as faith-based or community-based organizations, regional organizations, U.S. territories or possessions, eligible federal agencies, and other listed entities.

Are foreign (non-U.S.) institutions eligible to apply?

No. The opportunity states that non-U.S. (foreign) institutions are not eligible to apply.

Are foreign components allowed?

No. The opportunity language indicates foreign components are not allowed under NIH policy as referenced in the announcement.

Is cost sharing or matching required?

No. The announcement states that cost sharing or matching is not required.

When was this opportunity posted?

The record indicates it was posted on September 11, 2012.

What is the estimated total funding level listed for this opportunity?

The estimated total funding level listed is $7,500,000.

What are the listed closing and archive dates?

The record indicates an original closing date of September 7, 2015, a listed current closing date of January 7, 2014, and an archive date of February 7, 2014. This posting is described as archived.

Where were applicants directed to find the full official requirements and application instructions?

Applicants were directed to the NIH Grants Guide link associated with the announcement (PAR-12-283) for the full official requirements, budget structure, and application instructions.

Who is listed as a contact for access or technical issues with the announcement materials?

The contact listed is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV, indicated as a support channel for issues retrieving or linking to the announcement materials.

What career-stage transition is this program designed to address?

It is intended to reduce the career bottleneck between postdoctoral training and independent faculty-level (or equivalent) research by providing a predictable, milestone-driven pathway from mentored training to independence.

What outcomes does NIH/NIDCR emphasize for awardees over time?

The announcement emphasizes accelerating independence while maintaining rigorous mentorship and preparation, and building a strong cohort of NIH-supported independent investigators contributing to oral health and related disorders research priorities.

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