Opportunity Information: Apply for PAR 13 178

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIDCR Small Research Grants for Secondary Analysis of FaceBase Data (R03)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121 Oral Diseases and Disorders Research.
  • This funding opportunity was created on Apr 2, 2013 and posted on Apr 2, 2013.
  • Applicants must submit their applications by Sep 7, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: For profit organizations other than small businesses Public housing authorities/Indian housing authorities Small businesses County governments State governments Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education Public and State controlled institutions of higher education City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Native American tribal governments (Federally recognized).
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The NIDCR Small Research Grants for Secondary Analysis of FaceBase Data (R03) opportunity (PAR 13-178) is a National Institutes of Health discretionary grant program designed to fund small, focused research projects that make use of existing data generated by the FaceBase Consortium. FaceBase is building and sharing comprehensive datasets focused on midfacial development, and these datasets are made publicly available to the research community through www.facebase.org. The main point of this FOA is to support investigators who want to ask new scientific questions by reanalyzing and repurposing these already-collected FaceBase datasets, rather than generating entirely new primary datasets.

The scientific scope centers on craniofacial biology and disease. Projects are expected to be directly relevant to craniofacial development, human craniofacial conditions or traits, and/or animal models that inform those human conditions. Because FaceBase is a consortium resource with multiple data types and studies, the FOA explicitly encourages informatics-driven work, especially projects that integrate data across multiple FaceBase datasets. In practice, that means proposals that combine, harmonize, or computationally link different datasets to uncover patterns or relationships that may not be visible when a dataset is analyzed in isolation, such as connecting developmental timing, genotype-phenotype associations, morphometric measurements, gene expression patterns, or other consortium-provided modalities, depending on what is available in FaceBase at the time of analysis.

Mechanistically, this is an R03 small research grant, which is typically used for discrete, well-defined projects that can be completed with limited resources and within a shorter timeframe than larger mechanisms. The listed award ceiling is $200,000, and there is no cost sharing or matching requirement, which reduces barriers for applicants who may not have institutional funds to contribute. The funding activity category is Health, and it is associated with CFDA number 93.121 (Oral Diseases and Disorders Research), reflecting NIDCRs mission and the oral/craniofacial research focus.

Eligibility is broad and includes a wide range of domestic U.S. organizations such as public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (including small businesses and other for-profits), state and local governments, tribal governments and tribal organizations, independent school districts, public housing authorities, and special district governments. The FOA also makes clear that non-U.S. entities are eligible: foreign organizations and foreign institutions can apply, non-U.S. components of U.S. organizations are eligible, and foreign components (as defined by NIH policy) are allowed. It also explicitly includes categories such as HBCUs, Hispanic-serving institutions, AANAPISIs, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities, regional organizations, and faith-based or community-based organizations, signaling an intent to keep the applicant pool inclusive.

From an applicants perspective, the core expectation is a strong, clearly justified secondary analysis plan that leverages FaceBase data to produce meaningful new insights in craniofacial science. Competitive projects under this FOA would typically demonstrate a sound analytic strategy, appropriate statistical or computational methods, and a clear explanation of how the proposed work will advance understanding of craniofacial development or disease beyond what has already been published from the original datasets. Because the FOA emphasizes integration across datasets, proposals that thoughtfully address data harmonization, interoperability, reproducibility, and informatics workflows are particularly aligned with the program priorities.

Key administrative details in the archived listing include a posted and created date of April 2, 2013, an original and current closing date of September 7, 2016, and an archive date of October 8, 2016, indicating that this specific announcement is no longer active. The sponsoring agency is the National Institutes of Health (with NIDCR as the institute named in the title), and the full announcement was made available through the NIH grants guide at http://grants.nih.gov/grants/guide/pa-files/PAR-13-178.html. For technical issues accessing the announcement, the listing provides the NIH Office of Extramural Research webmaster contact (FBOWebmaster@OD.NIH.GOV).

Frequently Asked Questions (FAQs)

What is the NIDCR Small Research Grants for Secondary Analysis of FaceBase Data (R03) opportunity?

This opportunity (PAR 13-178) is a National Institutes of Health (NIH) discretionary grant program from NIDCR designed to fund small, focused research projects that conduct secondary analyses of existing datasets generated by the FaceBase Consortium.

What is the main purpose of this funding opportunity?

The purpose is to support investigators who want to ask new scientific questions by reanalyzing and repurposing already-collected FaceBase datasets, rather than creating entirely new primary datasets.

What is FaceBase?

FaceBase is a consortium effort that builds and shares comprehensive datasets focused on midfacial development. These datasets are made publicly available to the research community through www.facebase.org.

What type of research does this FOA support?

The scientific scope centers on craniofacial biology and disease. Projects are expected to be directly relevant to craniofacial development, human craniofacial conditions or traits, and/or animal models that inform those human conditions.

Does this program fund new data collection?

The emphasis is on secondary analysis of existing FaceBase data. The stated goal is to generate new insights by reanalyzing and repurposing already-collected datasets rather than generating entirely new primary datasets.

What kinds of approaches are encouraged?

The FOA explicitly encourages informatics-driven work, particularly projects that integrate data across multiple FaceBase datasets. Examples described in the opportunity include combining, harmonizing, or computationally linking datasets to uncover patterns that may not be visible when analyzing a single dataset in isolation.

What kinds of scientific questions might be addressed with integrated analyses?

The opportunity highlights potential cross-dataset connections such as developmental timing, genotype-phenotype associations, morphometric measurements, gene expression patterns, or other modalities available within FaceBase at the time of analysis.

What grant mechanism is used?

This is an NIH R03 small research grant mechanism, typically used for discrete, well-defined projects that can be completed with limited resources and within a shorter timeframe than larger grant mechanisms.

What is the maximum award amount?

The listed award ceiling is $200,000.

Is cost sharing or matching required?

No. The opportunity states there is no cost sharing or matching requirement.

What is the funding activity category?

The funding activity category is Health.

What CFDA number is associated with this opportunity?

The opportunity is associated with CFDA number 93.121 (Oral Diseases and Disorders Research).

Who is eligible to apply?

Eligibility is broad and includes many types of domestic U.S. organizations, including public and private institutions of higher education, nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (including small businesses and other for-profits), and various government entities (state, local, tribal), as well as independent school districts, public housing authorities, and special district governments.

Are foreign organizations eligible to apply?

Yes. The FOA indicates that non-U.S. entities are eligible: foreign organizations and foreign institutions can apply, non-U.S. components of U.S. organizations are eligible, and foreign components (as defined by NIH policy) are allowed.

Does the FOA identify specific institution categories as included?

Yes. It explicitly includes categories such as HBCUs, Hispanic-serving institutions, AANAPISIs, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities, as well as regional organizations and faith-based or community-based organizations.

What makes a project well-aligned with the program priorities?

Based on the description provided, strong alignment includes a clearly justified secondary analysis plan using FaceBase data, a sound analytic strategy with appropriate statistical or computational methods, and a clear explanation of how the work will advance understanding of craniofacial development or disease beyond what has already been published from the original datasets.

What additional elements are emphasized for competitive applications?

The FOA places special emphasis on integration across datasets. Proposals that thoughtfully address data harmonization, interoperability, reproducibility, and informatics workflows are described as particularly aligned with program priorities.

Is this funding opportunity still open?

No. The archived listing shows an original and current closing date of September 7, 2016, with an archive date of October 8, 2016, indicating this specific announcement is no longer active.

When was this announcement posted?

The archived listing includes a posted and created date of April 2, 2013.

Which agency sponsors this opportunity?

The sponsoring agency is the National Institutes of Health (NIH), with NIDCR named in the opportunity title.

Where can the full announcement be found?

The full announcement is available through the NIH Grants Guide at http://grants.nih.gov/grants/guide/pa-files/PAR-13-178.html.

Who should be contacted for technical issues accessing the announcement?

For technical issues accessing the announcement, the listing provides the NIH Office of Extramural Research webmaster contact: FBOWebmaster@OD.NIH.GOV.

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