Opportunity Information: Apply for PAR 14 301
Apply for PAR 14 301
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "NIDDK Central Repositories Non renewable Sample Access (X01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on Jul 30, 2014 and posted on Jul 30, 2014.
- Applicants must submit their applications by Jun 30, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Special district governments City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses State governments Public housing authorities/Indian housing authorities Private institutions of higher education County governments Small businesses Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The NIDDK Central Repositories Non-renewable Sample Access (X01) opportunity (Funding Opportunity Number PAR-14-301) is a National Institutes of Health (NIH) discretionary grant mechanism designed to help researchers gain access to limited, non-renewable biospecimens and associated data that are stored in the NIDDK Central Repositories. These repositories contain samples collected from numerous large, high-value clinical studies in areas relevant to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), including diabetes, digestive diseases, kidney and urologic conditions, and related nutrition and metabolic health topics. The main purpose of the program is to enable investigators to carry out new scientific analyses using existing, carefully curated materials that cannot be replaced once used, thereby extending the impact of prior major studies and accelerating discovery without the time and expense of collecting new cohorts.
A central feature of this FOA is that it focuses specifically on non-renewable specimens, meaning the requested materials are finite and their use must be justified carefully. Applicants are expected to review what is available through the NIDDK Central Repositories and align their proposed work with the specific sample types, quantities, and linked study data that exist. The repository website (www.niddkrepository.org) serves as the primary resource for identifying available studies and biospecimens. A key application requirement is documentation from the NIDDK Central Repositories confirming sample availability, which helps ensure that the proposal is feasible and that the request matches what the repository can actually provide. In practical terms, investigators should plan ahead to communicate with the repository, confirm inventory and constraints, and incorporate that confirmation into the application materials.
From an administrative and eligibility standpoint, this is an NIH grant categorized under the activity area of Food and Nutrition Health and associated with CFDA 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research). It does not require cost sharing or matching funds. The eligible applicant pool is broad and includes many types of U.S. organizations such as public and private institutions of higher education, nonprofits (including 501(c)(3) organizations and certain nonprofits without 501(c)(3) status), for-profit entities (including small businesses), independent school districts, and multiple levels of government (state, county, city/township, special district governments, and public housing authorities/Indian housing authorities). Tribal governments are eligible, including federally recognized tribal governments and other Indian/Native American tribal governments, along with tribally controlled colleges and universities.
The FOA also explicitly allows applications from non-U.S. entities. Foreign organizations and foreign institutions are eligible to apply, non-domestic components of U.S. organizations are eligible, and foreign components as defined in the NIH Grants Policy Statement are allowed. The eligibility language further highlights inclusion of a wide range of mission-based and serving institutions and community-aligned entities, including Alaska Native and Native Hawaiian Serving Institutions, AANAPISIs, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), faith-based or community-based organizations, U.S. territories or possessions, and eligible federal government agencies. This wide eligibility reflects the intent to make these unique repository resources accessible to a broad research community, provided the proposed use is justified and feasible given the limited nature of the specimens.
In terms of timing and lifecycle details provided in the source record, the opportunity was posted and created on July 30, 2014, with an original closing date of June 30, 2017, and it was archived on July 31, 2017. Additional official details were made available through the NIH Grants Guide page linked in the announcement (http://grants.nih.gov/grants/guide/pa-files/PAR-14-301.html). For technical issues accessing the announcement online, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Overall, this FOA is best understood as a structured pathway for investigators to request and justify use of scarce, irreplaceable biospecimens from landmark NIDDK-related clinical studies, with the expectation that applicants will confirm availability with the repository in advance and propose analyses that make responsible, high-impact use of these limited materials.
FAQs: NIDDK Central Repositories Non-renewable Sample Access (X01) (PAR-14-301)
What is the NIDDK Central Repositories Non-renewable Sample Access (X01) opportunity?
It is an NIH discretionary grant mechanism (X01) under Funding Opportunity Number PAR-14-301 designed to help researchers obtain access to limited, non-renewable biospecimens and associated data stored in the NIDDK Central Repositories.
What is the main purpose of this FOA?
The goal is to enable investigators to conduct new scientific analyses using existing, carefully curated biospecimens and linked study data from prior major clinical studies, extending the impact of those studies and accelerating discovery without the time and expense of collecting new cohorts.
What does "non-renewable specimens" mean in this program?
Non-renewable specimens are finite materials that cannot be replaced once used. Because they are limited, requests must be carefully justified and aligned with what is actually available in the repository.
Where are the biospecimens and data stored?
The biospecimens and associated data are stored in the NIDDK Central Repositories.
What research areas are most relevant to the samples in these repositories?
The repositories include samples collected from numerous large, high-value clinical studies relevant to NIDDK mission areas, including diabetes, digestive diseases, kidney and urologic conditions, and related nutrition and metabolic health topics.
How do applicants figure out which studies and biospecimens are available?
The repository website (www.niddkrepository.org) is the primary resource for identifying available studies and biospecimens. Applicants are expected to review what is available and shape their proposal around the sample types, quantities, and linked study data that exist.
Is there a requirement to confirm sample availability before applying?
Yes. A key application requirement is documentation from the NIDDK Central Repositories confirming sample availability. This confirmation supports feasibility and helps ensure the request matches repository inventory and constraints.
What practical planning steps does the FOA imply for applicants?
Applicants should plan ahead to communicate with the NIDDK Central Repositories, confirm inventory and constraints, and incorporate the repository's confirmation of availability into their application materials.
What makes this FOA different from collecting a new cohort?
Instead of creating a new study cohort, this program focuses on responsible use of existing, curated, and limited specimens and data from landmark clinical studies, enabling new analyses without the time and expense of new sample collection.
Which NIH institute is associated with this opportunity?
The opportunity is aligned with the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
What is the activity type or mechanism mentioned for this FOA?
The FOA uses the X01 mechanism and is described as an NIH discretionary grant mechanism to facilitate access to materials and data held by the NIDDK Central Repositories.
Is cost sharing or matching required?
No. The opportunity does not require cost sharing or matching funds.
What CFDA listing is associated with this program?
The program is associated with CFDA 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research).
Who is eligible to apply within the United States?
Eligibility is broad and includes public and private institutions of higher education, nonprofits (including 501(c)(3) organizations and certain nonprofits without 501(c)(3) status), for-profit entities (including small businesses), independent school districts, and multiple levels of government (state, county, city/township, special district governments, and public housing authorities/Indian housing authorities).
Are tribal governments and tribally affiliated institutions eligible?
Yes. Eligible applicants include federally recognized tribal governments and other Indian/Native American tribal governments, as well as tribally controlled colleges and universities.
Are non-U.S. (foreign) organizations eligible to apply?
Yes. The FOA explicitly allows applications from non-U.S. entities, including foreign organizations and foreign institutions.
Are non-domestic components of U.S. organizations allowed?
Yes. Non-domestic components of U.S. organizations are eligible, and foreign components (as defined in the NIH Grants Policy Statement) are allowed.
Does the FOA mention specific serving institutions or community-aligned entities as eligible?
Yes. The eligibility language highlights inclusion of a wide range of institutions and organizations, including Alaska Native and Native Hawaiian Serving Institutions, AANAPISIs, Hispanic-serving institutions, Historically Black Colleges and Universities (HBCUs), faith-based or community-based organizations, U.S. territories or possessions, and eligible federal government agencies.
When was this opportunity posted and when did it close?
The opportunity was posted and created on July 30, 2014. The original closing date was June 30, 2017, and it was archived on July 31, 2017.
Where can applicants find the official NIH Grants Guide announcement page?
The NIH Grants Guide page linked in the announcement is: http://grants.nih.gov/grants/guide/pa-files/PAR-14-301.html
Who is listed as the contact for technical issues accessing the announcement online?
For technical issues accessing the announcement online, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
What is the core expectation for how investigators should use these samples?
The FOA emphasizes responsible, well-justified, and high-impact use of scarce, irreplaceable biospecimens by aligning the proposed analyses with available sample types and quantities and confirming availability in advance.
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