Opportunity Information: Apply for PAR 10 090

  • The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "NIDDK Central Repositories Non renewable Sample Access (X01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
  • This funding opportunity was created on Jan 21, 2010 and posted on Jan 21, 2010.
  • Applicants must submit their applications by Jul 1, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments County governments Independent school districts City or township governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The NIDDK Central Repositories Non renewable Sample Access (X01) opportunity (Funding Opportunity Number PAR 10 090) is a National Institutes of Health program designed to let investigators request access to limited, non renewable biological samples and associated data that were collected during major NIDDK-supported clinical studies. The central idea is to make high-value, hard-to-replace specimens available for additional scientifically sound research questions, while ensuring that the remaining material is used carefully and only for well-justified projects. Details on what studies and specimen types are available are maintained by the NIDDK Central Repositories, and applicants are expected to start by reviewing repository holdings at https://www.niddkrepository.org.

A key requirement is that applicants must include documentation from the NIDDK Central Repositories confirming that the requested samples are actually available. Because these are non renewable samples, availability and stewardship are central to the review and access decision. The notice also flags an important restriction: samples from certain landmark studies (DPT-1, EDIC, and DPP) are handled under a separate solicitation, and those specific samples could not be requested through this FOA until November 1, 2010. In practical terms, that means an investigator interested in those collections would need to watch for and use the designated announcement rather than submitting through PAR 10 090 (at least until the stated date).

The mechanism used is the NIH X01 award type. In this context, the X01 functions as an access mechanism rather than a traditional research grant. These applications are coded as X01s, but there are no grant dollars attached. Receiving an X01 under this program does not provide research funding to the applicant; instead, it authorizes access to the approved specimens and any linked repository data under the repositorys terms and conditions. The number of projects that ultimately receive access is not set in advance and depends on two factors: how many applications are judged meritorious and whether sufficient quantities of the requested non renewable materials remain.

Eligibility is broad and includes many kinds of domestic and non-domestic organizations. Eligible applicants include public and private institutions of higher education, nonprofits (with or without 501(c)(3) status), for-profit organizations (including small businesses), tribal governments and tribal organizations, state and local governments (including counties, cities, townships, special districts, and independent school districts), public housing authorities/Indian housing authorities, U.S. territories or possessions, and foreign organizations. The eligibility section also explicitly mentions a variety of institution types such as HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities, and faith-based or community-based organizations, as well as eligible federal agencies and regional organizations.

Administratively, the opportunity was posted January 21, 2010, with an original and current closing date of July 1, 2011, and an archive date of August 1, 2011. It is categorized as a discretionary grant opportunity under NIH, tied to the CFDA listing 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), and it states that there is no cost sharing or matching requirement. For applicants or institutions that have trouble accessing the full announcement online, NIH lists the Office of Extramural Research webmaster as the contact point (FBOWebmaster@OD.NIH.GOV), and the full announcement link is provided through the NIH Guide for Grants and Contracts.

Frequently Asked Questions (FAQs)

What is the NIDDK Central Repositories Non renewable Sample Access (X01) opportunity (PAR 10 090)?

It is a National Institutes of Health (NIH) program that allows investigators to request access to limited, non renewable biological samples and associated data collected during major NIDDK-supported clinical studies. The goal is to make high-value, hard-to-replace specimens available for additional scientifically sound research questions while carefully stewarding the remaining material.

What is the main purpose of this program?

The program is designed to enable new, well-justified research using existing NIDDK repository specimens and linked data, while ensuring that non renewable samples are used sparingly and only for projects with strong scientific rationale.

What kinds of materials can be requested through this FOA?

Investigators may request access to limited, non renewable biological samples and associated repository data from major NIDDK-supported clinical studies. Specific studies and specimen types are maintained by the NIDDK Central Repositories.

Where can applicants find details on available studies and specimen types?

Applicants are expected to review the NIDDK Central Repositories holdings at https://www.niddkrepository.org, where details on what studies and specimen types are available are maintained.

Are applicants required to confirm that samples are available before applying?

Yes. A key requirement is that the application must include documentation from the NIDDK Central Repositories confirming that the requested samples are actually available.

Why is sample availability documentation required?

Because the samples are non renewable, availability and stewardship are central to the review and access decision. The program emphasizes careful use of finite specimen resources.

Are any specific study samples restricted or handled separately?

Yes. Samples from the DPT-1, EDIC, and DPP landmark studies are handled under a separate solicitation. The notice states these specific samples could not be requested through PAR 10 090 until November 1, 2010.

If a project needs DPT-1, EDIC, or DPP samples, what should the investigator do?

An investigator interested in those collections would need to watch for and use the designated separate announcement rather than submitting through PAR 10 090 (at least until the stated date of November 1, 2010).

What does the NIH X01 mechanism mean in this program?

The X01 functions as an access mechanism rather than a traditional research grant. An approved X01 authorizes access to the approved specimens and any linked repository data under the repository's terms and conditions.

Does an X01 award provide research funding or grant dollars?

No. These applications are coded as X01s, but there are no grant dollars attached. Receiving an X01 under this program does not provide research funding; it provides access authorization.

How many projects will receive access under this opportunity?

The number of projects is not set in advance. It depends on how many applications are judged meritorious and whether sufficient quantities of the requested non renewable materials remain.

What factors influence whether access is granted?

Access depends on (1) whether the application is judged meritorious and (2) whether sufficient quantities of the requested non renewable samples remain available.

Who is eligible to apply?

Eligibility is broad and includes many types of domestic and non-domestic organizations, including public and private institutions of higher education, nonprofits (with or without 501(c)(3) status), for-profit organizations (including small businesses), tribal governments and tribal organizations, state and local governments, public housing authorities/Indian housing authorities, U.S. territories or possessions, and foreign organizations.

Are specific institution types explicitly mentioned as eligible?

Yes. The eligibility section explicitly mentions institution types such as HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities, and faith-based or community-based organizations. It also notes eligible federal agencies and regional organizations.

Are foreign organizations eligible?

Yes. The eligibility description includes foreign organizations among eligible applicants.

Is cost sharing or matching required?

No. The opportunity states there is no cost sharing or matching requirement.

What agency and program area does this opportunity fall under?

It is an NIH opportunity associated with NIDDK (National Institute of Diabetes and Digestive and Kidney Diseases) and is tied to CFDA 93.847, Diabetes, Digestive, and Kidney Diseases Extramural Research.

What are the key dates for this opportunity?

The opportunity was posted January 21, 2010. The original and current closing date is July 1, 2011. The archive date is August 1, 2011.

Where is the full announcement hosted?

The full announcement link is provided through the NIH Guide for Grants and Contracts.

Who should be contacted if there are issues accessing the full announcement online?

NIH lists the Office of Extramural Research webmaster as the contact point for access issues: FBOWebmaster@OD.NIH.GOV.

What is the fundamental expectation for applicants before submitting?

Applicants are expected to start by reviewing repository holdings at https://www.niddkrepository.org and to include repository documentation confirming that the requested samples are available.

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