Opportunity Information: Apply for RFA RM 11 021
Apply for RFA RM 11 021
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIH Health Care Systems Research Collaboratory Coordinating Center (U54)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310 Trans NIH Research Support.
- This funding opportunity was created on Jan 24, 2012 and posted on Jan 24, 2012.
- Applicants must submit their applications by Apr 27, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
- Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public and State controlled institutions of higher education For profit organizations other than small businesses Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:
The NIH Health Care Systems Research Collaboratory Coordinating Center (U54) funding opportunity (RFA-RM-11-021) is a discretionary NIH cooperative agreement designed to establish a national hub that helps the NIH Health Care Systems (HCS) Research Collaboratory function smoothly and consistently across multiple real-world research projects. Rather than funding a single research study, this award supports a central Coordinating Center that provides leadership, shared infrastructure, and practical guidance for conducting research in direct partnership with health care systems. The overall aim is to make it easier, faster, and more reliable to run high-quality studies in routine care settings so that the results can directly improve health outcomes and how care is delivered.
A major focus of the Coordinating Center is to create and maintain a common playbook for doing research with health care systems. This includes developing, adapting, and encouraging adoption of technical guidelines, policy guidance, and best practices that address the real operational challenges of embedded research. In practice, that can mean standard approaches to study design in clinical settings, data use and management, privacy and regulatory considerations, stakeholder engagement, and workflows that reduce burden on clinicians, staff, and patients while still producing rigorous evidence. The emphasis is on practical, field-tested guidance that health systems can actually use, not just academic recommendations.
The Coordinating Center is also expected to work hands-on with each Demonstration Project team and their partnering health care systems. These Demonstration Projects are the studies carried out under the Collaboratory umbrella, and the Coordinating Center supports them by helping develop and test implementation plans and by providing technical, design, and coordination assistance. This support role typically involves troubleshooting operational barriers, harmonizing methods where appropriate, helping teams navigate system-specific constraints, and strengthening study execution so that projects can be implemented efficiently in busy care environments. Because this is a cooperative agreement, NIH involvement is generally more active than in a standard research grant, and the Coordinating Center serves as a key mechanism for coordinating across NIH and the participating project teams.
Another core responsibility is broad dissemination. The Coordinating Center must widely share Collaboratory-endorsed policies, best practices, and lessons learned from the Demonstration Projects, with the goal of accelerating broader participation by health care systems in research. The intent is to move beyond the individual projects and build reusable knowledge that helps other organizations, clinicians, and researchers conduct similar work. Dissemination is framed as a practical effort to inform best practices for engaging patients, practitioners, and staff in research that is embedded in care delivery and aimed at measurable improvements.
Operationally, the Coordinating Center serves as the central resource for the program and provides administrative and logistical support for the Collaboratory’s Steering Committee and its subcommittees. This implies responsibility for organizing meetings, supporting governance processes, coordinating cross-project communication, and maintaining shared resources that keep the overall program aligned and productive. In other words, the Center is expected to function as both a technical backbone and a management backbone for the entire Collaboratory.
Key opportunity details include an estimated total funding level of $2,000,000 for the announcement, with no cost sharing or matching requirement. The award mechanism is a cooperative agreement (U54), and the activity category is health. The opportunity was posted on January 24, 2012, with an original and current closing date of April 27, 2012, and an archive date of May 28, 2012. The CFDA number listed is 93.310 (Trans-NIH Research Support).
Eligibility is broad across U.S.-based organizations and includes nonprofits (both with and without 501(c)(3) status), small businesses, for-profit entities (other than small businesses), public and state-controlled institutions of higher education, private institutions of higher education, and other eligible applicants as specified. The announcement explicitly includes eligibility for Alaska Native and Native Hawaiian Serving Institutions, Hispanic Serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs). Foreign institutions are not eligible, and non-U.S. components of U.S. organizations are not eligible; foreign components as defined by NIH policy are not allowed. The sponsoring agency is the National Institutes of Health, and the full announcement was made available through the NIH grants website link provided in the source.
Frequently Asked Questions (FAQs)
What is this NIH funding opportunity?
This opportunity is the NIH Health Care Systems Research Collaboratory Coordinating Center (U54) funding opportunity (RFA-RM-11-021). It is a discretionary NIH cooperative agreement intended to establish a national Coordinating Center that serves as a central hub for the NIH Health Care Systems (HCS) Research Collaboratory.
What is the main purpose of the Coordinating Center?
The Coordinating Center is designed to help the Collaboratory function smoothly and consistently across multiple real-world research projects. It provides leadership, shared infrastructure, and practical guidance so high-quality studies can be carried out in routine care settings and produce results that can improve health outcomes and care delivery.
Does this award fund a single research study?
No. The award does not primarily fund one standalone research study. Instead, it supports a central Coordinating Center that helps multiple Demonstration Projects operate effectively by providing coordination, technical support, and shared resources.
What is the award mechanism and why does it matter?
The mechanism is a cooperative agreement (U54). This matters because NIH involvement is generally more active than with a standard research grant, and the Coordinating Center plays a key role in coordinating activities across NIH and participating project teams.
What kinds of activities is the Coordinating Center expected to support?
The Coordinating Center is expected to provide leadership and shared infrastructure, offer practical guidance for conducting research in direct partnership with health care systems, and deliver hands-on support to Demonstration Project teams to help them plan and execute studies efficiently in routine care environments.
What is meant by “embedded research†in this opportunity?
Based on the description, the focus is on conducting research directly within real-world health care systems and routine care settings. The aim is to reduce burden on clinicians, staff, and patients while still generating rigorous evidence that can improve care delivery and outcomes.
What is the “common playbook†the Coordinating Center is supposed to create?
A major focus is developing and maintaining a common playbook for doing research with health care systems. This includes technical guidelines, policy guidance, and best practices that address practical operational challenges of conducting studies in clinical settings.
What topics might the playbook cover?
The playbook may include standard approaches and guidance related to study design in clinical settings, data use and management, privacy and regulatory considerations, stakeholder engagement, and workflows that reduce burden in busy care environments while maintaining rigorous evidence generation.
Is the guidance expected to be theoretical or practical?
The emphasis is on practical, field-tested guidance that health systems can actually use, rather than purely academic recommendations.
What are “Demonstration Projects†in the Collaboratory?
Demonstration Projects are the studies carried out under the Collaboratory umbrella. The Coordinating Center is expected to work hands-on with each Demonstration Project team and their partnering health care systems.
How does the Coordinating Center support Demonstration Projects?
Support includes helping develop and test implementation plans, providing technical and design assistance, coordinating across teams, troubleshooting operational barriers, harmonizing methods where appropriate, helping teams navigate system-specific constraints, and strengthening study execution in routine care environments.
What does “harmonizing methods†mean in this context?
As described, the Coordinating Center may help align or standardize methods across projects where appropriate, so that studies can be executed more consistently across multiple health care systems while still accounting for system-specific constraints.
What is the role of dissemination in this award?
Broad dissemination is a core responsibility. The Coordinating Center must widely share Collaboratory-endorsed policies, best practices, and lessons learned from Demonstration Projects to accelerate broader participation by health care systems in research and to build reusable knowledge beyond individual projects.
Who is the dissemination intended to reach?
The intent is to inform broader best practices for engaging patients, practitioners, and staff in embedded research. The description indicates the dissemination is meant to help other organizations, clinicians, and researchers conduct similar work in care delivery settings.
What administrative and governance support is expected from the Coordinating Center?
The Coordinating Center serves as the central resource for the program and provides administrative and logistical support for the Collaboratory’s Steering Committee and its subcommittees. This includes organizing meetings, supporting governance processes, coordinating cross-project communication, and maintaining shared resources to keep the program aligned and productive.
How much funding is available under this announcement?
The estimated total funding level for the announcement is $2,000,000.
Is cost sharing or matching required?
No. The opportunity states there is no cost sharing or matching requirement.
What is the activity category?
The activity category is health.
Which agency is sponsoring this opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
What is the CFDA number for this opportunity?
The CFDA number listed is 93.310 (Trans-NIH Research Support).
When was the opportunity posted and when did it close?
The opportunity was posted on January 24, 2012. The original and current closing date is April 27, 2012. The archive date is May 28, 2012.
Who is eligible to apply?
Eligibility is broad across U.S.-based organizations and includes nonprofits (with or without 501(c)(3) status), small businesses, for-profit entities (other than small businesses), public and state-controlled institutions of higher education, private institutions of higher education, and other eligible applicants as specified in the announcement.
Are minority-serving institutions explicitly included in eligibility?
Yes. The announcement explicitly includes Alaska Native and Native Hawaiian Serving Institutions, Hispanic Serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and Tribally Controlled Colleges and Universities (TCCUs) as eligible applicants.
Are foreign institutions eligible to apply?
No. Foreign institutions are not eligible.
Are non-U.S. components of U.S. organizations eligible?
No. Non-U.S. components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed.
Where was the full announcement made available?
The full announcement was made available through the NIH grants website link referenced in the source information.
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