Opportunity Information: Apply for PA 09 036
Apply for PA 09 036
- The National Institutes of Health in the education employment, labor and training food and nutrition health income security and social services sector is offering a public funding opportunity titled "NIH Pathway to Independence Award (K99/R00)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121 Oral Diseases and Disorders Research 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.213 Research and Training in Complementary and Integrative Health 93.233 National Center on Sleep Disorders Research 93.279 Drug Abuse and Addiction Research Programs 93.281 Mental Health Research Career/Scientist Development Awards 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.361 Nursing Research 93.389 National Center for Research Resources 93.398 Cancer Research Manpower 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.855 Allergy, Immunology and Transplantation Research 93.856 Microbiology and Infectious Diseases Research 93.859 Biomedical Research and Research Training 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research 93.867 Vision Research 93.879 Medical Library Assistance 93.989 International Research and Research Training.
- This funding opportunity was created on Dec 17, 2009 and posted on Dec 11, 2008.
- Applicants must submit their applications by Jan 7, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) State governments Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education Native American tribal governments (Federally recognized).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The NIH Pathway to Independence Award (K99/R00) is a career development grant designed to help promising postdoctoral researchers move more quickly from mentored training into independent research careers. Its central goal is to strengthen the long-term pipeline of NIH-supported investigators by supporting a structured transition: first, a mentored phase while the applicant is still in a postdoctoral setting, and then an independent phase once the applicant secures a stable, independent research position. In practice, the program is meant to shorten the time it typically takes for talented scientists to reach research independence, while also helping them build a foundation for future independent funding from NIH or other sources.
This opportunity uses the K99/R00 funding mechanism, which is intentionally split into two connected stages. The K99 portion supports the candidate during a mentored postdoctoral appointment, where the emphasis is on advanced training, gaining additional skills, producing strong research outputs, and preparing for independence. The R00 portion supports the same individual after they move into an independent position, helping them establish a research program as an independent investigator. The idea is continuity: the award supports a planned progression from guided development to самостоятель leadership of a research project, with the expectation that the awardee will be positioned to compete successfully for major independent research grants.
NIH notes that applicants are encouraged to contact the relevant NIH Institute or Center staff before applying, since program priorities, allowable budgets, and other expectations can vary across NIH components. The program spans a wide range of biomedical, behavioral, and health-related research areas, reflected in the many CFDA listings associated with the announcement. These include fields such as cancer, cardiovascular and lung disease, diabetes and kidney disease, neurological disorders, mental health, drug abuse and addiction, infectious diseases, aging, child health, vision research, nursing research, genomics, sleep research, and complementary and integrative health, among others. That breadth signals that the award is not limited to a single discipline; instead, it is a career-transition mechanism that many NIH Institutes and Centers can use to develop researchers aligned with their missions.
From an administrative standpoint, the opportunity is a discretionary grant offered by the National Institutes of Health. It explicitly states there is no cost-sharing or matching requirement. Eligibility is broad and includes many organization types that commonly host postdoctoral researchers and early independent investigators, such as public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status), for-profit organizations (other than small businesses), small businesses, state governments, tribal governments and tribal organizations, and various mission-serving institutions and community-based organizations. The listing also mentions additional eligible categories such as Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities, Tribally Controlled Colleges and Universities, regional organizations, U.S. territories or possessions, eligible federal agencies, and faith-based or community-based organizations, emphasizing that NIH intends the mechanism to be accessible across a wide range of research environments.
The specific opportunity referenced is Funding Opportunity Number PA 09 036, titled "NIH Pathway to Independence Award (K99/R00)." It was posted in December 2008, with the archived record showing closing dates that culminated in early 2010 and an archive date in February 2010. Even though this particular announcement is archived, the K99/R00 mechanism is a well-known NIH pathway program, and prospective applicants typically need to consult the current version of the FOA and the Institute- or Center-specific guidance to confirm the latest eligibility rules, timelines, budget limits, and review criteria. The source includes an NIH link to the full announcement and provides contact support through the NIH Office of Extramural Research (OER) webmaster for access or technical issues.
Frequently Asked Questions (FAQs): NIH Pathway to Independence Award (K99/R00)
What is the NIH Pathway to Independence Award (K99/R00)?
The NIH Pathway to Independence Award (K99/R00) is a career development grant intended to help promising postdoctoral researchers transition more quickly from mentored postdoctoral training into independent research careers. It is designed to strengthen the long-term pipeline of NIH-supported investigators by supporting a structured progression from supervised development to independent research leadership.
What is the central goal of the K99/R00 program?
The central goal is to shorten the time it typically takes for talented scientists to achieve research independence while helping them build a foundation for future independent funding from NIH or other sources. The program is set up to support continuity from a mentored postdoctoral phase into an independent investigator phase.
How is the K99/R00 award structured?
The mechanism is intentionally split into two connected stages. The K99 portion supports a mentored phase during a postdoctoral appointment, focused on advanced training, skill development, producing research outputs, and preparing for independence. The R00 portion supports the same individual after they move into an independent position, helping them establish an independent research program.
What does the K99 (mentored) phase support?
Based on the description provided, the K99 phase supports the candidate while they remain in a postdoctoral setting. The emphasis is on advanced training, gaining additional skills, generating strong research outputs, and preparing to become an independent investigator.
What does the R00 (independent) phase support?
The R00 phase supports the awardee after they secure a stable, independent research position. It is intended to help them establish their research program as an independent investigator and position them to compete for major independent research grants.
Is the K99/R00 meant to support the same person across both phases?
Yes. The program is described as a continuity mechanism that supports the same individual through a planned transition from mentored development (K99) to independent research leadership (R00).
What kinds of research areas does this opportunity cover?
The opportunity spans a wide range of biomedical, behavioral, and health-related research areas. Examples listed include cancer; cardiovascular and lung disease; diabetes and kidney disease; neurological disorders; mental health; drug abuse and addiction; infectious diseases; aging; child health; vision research; nursing research; genomics; sleep research; and complementary and integrative health, among others.
Is this award limited to one scientific discipline or NIH Institute?
No. The breadth of CFDA listings and the range of research areas indicate it is not limited to a single discipline. It is a career-transition mechanism that multiple NIH Institutes and Centers can use to develop researchers aligned with their missions.
Why does NIH encourage applicants to contact Institute or Center staff before applying?
NIH encourages contact because program priorities, allowable budgets, and other expectations can vary across NIH Institutes and Centers. Discussing fit and requirements ahead of time can help align an application with the relevant component’s mission and guidance.
What type of award is this from an administrative standpoint?
It is described as a discretionary grant offered by the National Institutes of Health (NIH).
Is cost-sharing or matching required?
No. The opportunity explicitly states there is no cost-sharing or matching requirement.
What types of organizations are eligible to apply or host researchers under this opportunity?
Eligibility is described as broad and includes many organization types commonly involved in research and training environments. Examples listed include public and private institutions of higher education; nonprofit organizations (with and without 501(c)(3) status); for-profit organizations (other than small businesses); small businesses; state governments; tribal governments and tribal organizations; and various mission-serving and community-based organizations.
Do mission-serving institutions and community-based organizations appear to be eligible?
Yes. The listing explicitly mentions mission-serving institutions and community-based organizations among eligible categories.
Are minority-serving and tribally affiliated institutions included in the eligible categories?
Yes. The listing includes categories such as Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities.
Are U.S. territories and possessions included in eligible applicant categories?
Yes. The listing mentions U.S. territories or possessions among eligible categories.
Are eligible federal agencies mentioned as potentially eligible?
Yes. The listing includes eligible federal agencies among the eligible categories.
Are faith-based organizations mentioned as eligible?
Yes. The listing includes faith-based organizations (along with community-based organizations) among the eligible categories.
What is the Funding Opportunity Number (FOA number) referenced?
The referenced Funding Opportunity Number is PA 09 036, titled "NIH Pathway to Independence Award (K99/R00)."
When was this specific opportunity posted, and what is its status?
The referenced announcement was posted in December 2008. The archived record shows closing dates culminating in early 2010 and an archive date in February 2010. The information provided indicates that this particular announcement is archived.
If the referenced FOA is archived, does that mean the K99/R00 mechanism no longer exists?
The information provided notes that even though this particular announcement is archived, the K99/R00 mechanism is a well-known NIH pathway program. Prospective applicants are advised to consult the current version of the FOA and any Institute- or Center-specific guidance for up-to-date requirements.
What should prospective applicants do to confirm current eligibility rules, timelines, and budgets?
They should consult the current version of the Funding Opportunity Announcement and review Institute- or Center-specific guidance to confirm the latest eligibility rules, timelines, budget limits, and review criteria, since these can change and can vary by NIH component.
Where can applicants find the full announcement and who can help with access or technical issues?
The source includes an NIH link to the full announcement and provides contact support through the NIH Office of Extramural Research (OER) webmaster for access or technical issues.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 09 036) also looked into and applied for these:
| Funding Opportunity |
|---|
| Mentored Quantitative Research Development Award (K25) Apply for PA 09 039 Funding Number: PA 09 039 Agency: National Institutes of Health Category: Education Employment, Labor and Training Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Clinical Scientist Research Career Development Award (Parent K08) Apply for PA 10 059 Funding Number: PA 10 059 Agency: National Institutes of Health Category: Education Employment, Labor and Training Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| NIH Pathway to Independence Award (Parent K99/R00) Apply for PA 10 063 Funding Number: PA 10 063 Agency: National Institutes of Health Category: Education Employment, Labor and Training Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Quantitative Research Development Award (Parent K25) Apply for PA 10 062 Funding Number: PA 10 062 Agency: National Institutes of Health Category: Education Employment, Labor and Training Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
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