Opportunity Information: Apply for PA 10 063

  • The National Institutes of Health in the education employment, labor and training food and nutrition health income security and social services sector is offering a public funding opportunity titled "NIH Pathway to Independence Award (Parent K99/R00)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121 Oral Diseases and Disorders Research 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.213 Research and Training in Complementary and Integrative Health 93.233 National Center on Sleep Disorders Research 93.279 Drug Abuse and Addiction Research Programs 93.281 Mental Health Research Career/Scientist Development Awards 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.307 Minority Health and Health Disparities Research 93.361 Nursing Research 93.389 National Center for Research Resources 93.398 Cancer Research Manpower 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.855 Allergy, Immunology and Transplantation Research 93.856 Microbiology and Infectious Diseases Research 93.859 Biomedical Research and Research Training 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research 93.867 Vision Research 93.879 Medical Library Assistance 93.989 International Research and Research Training.
  • This funding opportunity was created on Apr 8, 2011 and posted on Dec 16, 2009.
  • Applicants must submit their applications by May 7, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Small businesses City or township governments Private institutions of higher education County governments Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Independent school districts Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities For profit organizations other than small businesses Special district governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The NIH Pathway to Independence Award (Parent K99/R00), funding opportunity number PA 10 063, is a discretionary NIH grant program built to help promising postdoctoral researchers move into independent faculty-style research positions faster than the traditional timeline. The central goal is workforce development for biomedical and behavioral research: NIH wants to grow and retain a strong pipeline of new, high-quality independent investigators by supporting the crucial transition period between a mentored postdoc and an independent research appointment. In practical terms, the program is meant to reduce the time people spend in extended postdoctoral training by giving them a structured, funded path that starts with mentorship and then shifts to independence once they secure an appropriate research position.

This opportunity uses the K99/R00 mechanism, which is specifically designed as a two-phase award. The first phase (K99) supports a candidate while they are still in a mentored postdoctoral or equivalent position, with the emphasis on completing key training, building a strong publication record, and generating the foundation for an independent research program. The second phase (R00) is intended to support the candidate after they have transitioned into a stable independent research position, where they can run their own project and begin competing successfully for independent NIH or other research funding. NIH strongly encourages applicants to speak with the relevant Institute or Center (IC) program staff ahead of time because participating ICs can differ in priorities, budget expectations, and programmatic fit, and NIH provides a table of Institute and Center contacts to guide those conversations.

Funding is contingent on congressional appropriations, NIH budget availability, and the number of strong applications received. NIH projected a relatively large annual cohort for this mechanism, anticipating roughly 150 to 200 competing K99/R00 awards each fiscal year under this announcement, assuming there is a sufficient pool of meritorious proposals. The program spans a wide range of NIH scientific areas, which is reflected in the many CFDA numbers associated with it, covering topics such as cancer, cardiovascular and pulmonary disease, diabetes and kidney research, neuroscience, mental health, infectious disease and microbiology, aging, child health, vision, nursing research, minority health and health disparities, complementary and integrative health, genome research, and other core biomedical research and training domains.

Eligibility is broad at the organizational level and includes many types of institutions and organizations that can serve as applicant or host entities, such as public and private institutions of higher education, nonprofits (including those with and without 501(c)(3) status), for-profit organizations, small businesses, state and local governments, independent school districts, public housing authorities/Indian housing authorities, and tribal governments and tribal organizations. The announcement also explicitly notes additional eligible categories such as Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. There is no cost sharing or matching requirement associated with this opportunity.

Key administrative details included in the listing are that the opportunity was posted December 16, 2009, and the archived record shows an original closing date of January 7, 2013, with a current closing date shown as May 7, 2011, and an archive date of June 7, 2011. The full announcement is available through NIH’s grants guide at http://grants.nih.gov/grants/guide/pa files/PA 10 063.html. For technical issues accessing or linking to the announcement, NIH directs applicants to the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.

FAQs: NIH Pathway to Independence Award (Parent K99/R00) - PA-10-063

1) What is the NIH Pathway to Independence Award (Parent K99/R00)?

The NIH Pathway to Independence Award (Parent K99/R00) is a discretionary NIH grant program designed to help promising postdoctoral researchers transition more quickly from mentored postdoctoral training into independent, faculty-style research positions.

2) What is the main goal of the K99/R00 program?

The central goal is workforce development for biomedical and behavioral research. NIH aims to strengthen and retain a pipeline of high-quality independent investigators by supporting the critical transition period between a mentored postdoc role and an independent research appointment.

3) How does this program reduce time spent in postdoctoral training?

It provides a structured, funded path that begins with mentored support and then shifts to support for independence once the awardee secures an appropriate independent research position.

4) What funding mechanism does this opportunity use?

This opportunity uses the K99/R00 mechanism, which is a two-phase award designed to support both mentored postdoctoral development and the subsequent transition to an independent research position.

5) What is the K99 phase intended to support?

The K99 phase supports the candidate while they are in a mentored postdoctoral (or equivalent) position. The emphasis is on completing key training, building a strong publication record, and generating the foundation for an independent research program.

6) What is the R00 phase intended to support?

The R00 phase is intended to support the candidate after they transition into a stable independent research position. During this phase, the candidate is expected to run their own project and begin competing successfully for independent NIH or other research funding.

7) Does NIH recommend contacting program staff before applying?

Yes. NIH strongly encourages applicants to speak with the relevant Institute or Center (IC) program staff ahead of time because participating ICs may differ in scientific priorities, budget expectations, and programmatic fit.

8) How can applicants find the right NIH Institute or Center contact?

NIH provides a table of Institute and Center contacts in the announcement to help guide pre-application conversations with the appropriate program staff.

9) How many K99/R00 awards does NIH expect to make each year under this announcement?

NIH anticipated roughly 150 to 200 competing K99/R00 awards each fiscal year under this announcement, assuming a sufficient pool of meritorious proposals.

10) Is funding guaranteed?

No. Funding is contingent on congressional appropriations, NIH budget availability, and the number of strong applications received.

11) What scientific areas does this opportunity cover?

The program spans a wide range of NIH scientific areas across biomedical and behavioral research. The listing associates many CFDA numbers reflecting areas such as cancer; cardiovascular and pulmonary disease; diabetes and kidney research; neuroscience; mental health; infectious disease and microbiology; aging; child health; vision; nursing research; minority health and health disparities; complementary and integrative health; genome research; and other core biomedical research and training domains.

12) What types of organizations are eligible to apply or serve as host institutions?

Eligibility is broad at the organizational level and includes public and private institutions of higher education, nonprofits (with or without 501(c)(3) status), for-profit organizations, small businesses, state and local governments, independent school districts, public housing authorities/Indian housing authorities, and tribal governments and tribal organizations.

13) Are there additional institution categories explicitly listed as eligible?

Yes. The announcement also notes categories including Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions.

14) Is there a cost sharing or matching requirement?

No. The opportunity states there is no cost sharing or matching requirement.

15) What is the funding opportunity number for this announcement?

The funding opportunity number is PA 10 063.

16) Where is the full NIH announcement posted?

The full announcement is available through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PA-10-063.html

17) What are the key dates shown in the listing?

The listing notes the opportunity was posted on December 16, 2009. The archived record shows an original closing date of January 7, 2013, a current closing date shown as May 7, 2011, and an archive date of June 7, 2011.

18) Who should be contacted for technical issues accessing or linking to the announcement?

For technical issues accessing or linking to the announcement, NIH directs applicants to contact the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.

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Funding Amount: Case Dependent

 

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