Opportunity Information: Apply for RFA OD 14 005
Apply for RFA OD 14 005
- The National Institutes of Health in the education environment food and nutrition health income security and social services sector is offering a public funding opportunity titled "NIH Research Evaluation and Commercialization Hub (REACH) Awards (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.121 Oral Diseases and Disorders Research 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.213 Research and Training in Complementary and Integrative Health 93.233 National Center on Sleep Disorders Research 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.307 Minority Health and Health Disparities Research 93.350 National Center for Advancing Translational Sciences 93.351 Research Infrastructure Programs 93.361 Nursing Research 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.399 Cancer Control 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.855 Allergy and Infectious Diseases Research 93.856 Microbiology and Infectious Diseases Research 93.859 Biomedical Research and Research Training 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research 93.867 Vision Research 93.879 Medical Library Assistance.
- This funding opportunity was created on Apr 25, 2014 and posted on Apr 25, 2014.
- Applicants must submit their applications by Jun 26, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $9,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $1,000,000.00 in funding.
- Eligible applicants include: Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Opportunity Summary:
The NIH Research Evaluation and Commercialization Hub (REACH) Awards (U01) opportunity, Funding Opportunity Number RFA-OD-14-005, was a National Institutes of Health (NIH) initiative designed to push promising biomedical discoveries out of the lab and closer to real-world use. The core idea was to fund a small number of proof-of-concept centers, referred to as REACH Hubs, that could consistently identify high-potential early-stage technologies and then provide the kind of structured support that helps those technologies become commercially viable products. NIH framed the goal in practical terms: accelerate translation into products that improve patient care and enhance health, rather than leaving innovations stalled at the prototype or publication stage.
The program emphasized building an institutional “engine†for translation rather than simply funding isolated projects. Each Hub was expected to establish infrastructure for scouting and selecting the most promising technologies within NIH’s mission areas, using some form of evaluation and prioritization process. Once a technology was selected, the Hub could provide direct support for product definition work. This included activities like feasibility studies, prototype development, and other proof-of-concept efforts that reduce technical risk and clarify what would be required for eventual commercialization. In other words, the funding was meant to bridge the gap between academic discovery and the early development milestones that investors, strategic partners, and industry typically expect before engaging.
A defining feature of REACH was the coordinated access to cross-functional expertise that early technologies usually lack. Hubs were expected to make expertise available not just on the science side, but also in areas that often determine whether a product ever reaches patients: regulatory strategy, reimbursement and market access considerations, business development, legal and intellectual property guidance, and disciplined project management. Beyond supporting specific technologies, NIH also wanted these Hubs to cultivate talent. The announcement explicitly called for skills development and hands-on experience in entrepreneurship, signaling that part of the deliverable was a stronger, more experienced community of biomedical innovators who understand commercialization pathways.
The funding mechanism was a cooperative agreement (U01), which generally implies substantial NIH involvement during the project period compared to a standard grant. Practically, this tends to mean the awardees should be prepared for active coordination with NIH program staff, milestone-driven progress expectations, and an emphasis on measurable translation outcomes. The activity categories listed for the opportunity span a very broad range of NIH-relevant domains (for example, cancer, cardiovascular disease, mental health, substance use, infectious disease, aging, genomics, minority health and health disparities, nursing research, and more), reinforcing that the program was not disease-specific. Instead, it targeted the commercialization “translation bottleneck†that cuts across biomedical fields.
The opportunity placed major weight on forming public-private partnerships and bringing in additional non-federal funding. NIH described this as critical to success, which is consistent with the program’s commercialization focus: external partners can provide market insight, customer discovery, product requirements, later-stage financing, and a path to licensing or startup formation. In effect, the REACH Hub model was intended to use NIH support as an initial catalytic investment, while building relationships and co-investment structures that could sustain a pipeline of translational projects beyond federal dollars alone.
From an administrative standpoint, the opportunity was posted April 25, 2014, with an original and current closing date of June 26, 2014, and it was archived July 27, 2014. NIH estimated total funding at $9,000,000, with an award ceiling of $1,000,000. The announcement indicated no cost sharing or matching requirement, although it still strongly encouraged (and arguably expected) leveraging non-federal resources through partnerships and other mechanisms.
Eligibility centered on institutions capable of operating a commercialization and proof-of-concept hub. Eligible applicants included public and state-controlled institutions of higher education and private institutions of higher education, along with specific categories of institutions emphasized in NIH eligibility language such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American and Native American Pacific Islander-Serving Institutions (AANAPISIs). Non-U.S. (foreign) institutions were not eligible to apply, and non-U.S. components of U.S. organizations were also not eligible; however, foreign components as defined in the NIH Grants Policy Statement could be allowed in some circumstances.
In summary, REACH (U01) was structured to help institutions create a repeatable, milestone-driven pathway for moving early biomedical innovations toward commercialization. It combined selective technology sourcing, targeted proof-of-concept funding, integrated business and regulatory expertise, and entrepreneur training, while pushing awardees to develop strong public-private partnerships and attract additional non-federal support. The intended outcome was a more reliable pipeline of investable, translatable technologies positioned to become products that ultimately benefit patients.
NIH REACH Awards (U01) - FAQs (RFA-OD-14-005)
What is the NIH Research Evaluation and Commercialization Hub (REACH) Awards (U01) program?
The NIH Research Evaluation and Commercialization Hub (REACH) Awards (U01) was an NIH initiative designed to move promising early-stage biomedical discoveries out of the lab and closer to real-world use. The program funded a small number of proof-of-concept centers, called REACH Hubs, to help consistently identify high-potential technologies and provide structured support to make them more commercially viable.
What is the Funding Opportunity Number for this program?
The Funding Opportunity Number is RFA-OD-14-005.
What is the main goal of REACH?
The goal was to accelerate the translation of biomedical innovations into products that improve patient care and enhance health, specifically by reducing the gap between academic discovery and the development milestones typically needed before investors or industry partners engage.
Is REACH funding meant for individual projects or for building a broader program?
REACH emphasized building a repeatable institutional "engine" for translation. Rather than focusing only on isolated projects, each funded Hub was expected to create infrastructure and processes to scout, evaluate, prioritize, and support a pipeline of technologies over time.
What is a REACH Hub?
A REACH Hub is a proof-of-concept center funded under this opportunity. Hubs were expected to identify and select promising NIH-mission-relevant technologies and then provide structured, milestone-driven support to move those technologies toward commercialization.
What types of activities could a REACH Hub support for selected technologies?
For technologies selected through the Hub's evaluation and prioritization process, the Hub could support product-definition and proof-of-concept work such as feasibility studies, prototype development, and other activities intended to reduce technical risk and clarify what is required for eventual commercialization.
What kinds of expertise were Hubs expected to provide beyond scientific support?
REACH expected coordinated access to cross-functional expertise that commonly affects commercialization outcomes, including regulatory strategy, reimbursement and market access considerations, business development, legal and intellectual property guidance, and disciplined project management.
Did REACH include training or workforce development expectations?
Yes. NIH explicitly called for skills development and hands-on experience in entrepreneurship, aiming to build a stronger community of biomedical innovators who understand commercialization pathways.
What does the U01 mechanism mean for this program?
The award used a cooperative agreement (U01) mechanism, which generally implies substantial NIH involvement during the project period compared to a standard grant. Awardees were expected to coordinate actively with NIH program staff and operate with milestone-driven progress expectations and measurable translation outcomes.
Was this opportunity focused on a specific disease area?
No. The opportunity spanned a broad range of NIH-relevant domains (including areas such as cancer, cardiovascular disease, mental health, substance use, infectious disease, aging, genomics, minority health and health disparities, and nursing research). The emphasis was on addressing a common commercialization and translation bottleneck across biomedical fields rather than targeting one disease area.
How important were partnerships to the REACH program?
Public-private partnerships were a major emphasis. NIH described forming partnerships and bringing in additional non-federal funding as critical to success, consistent with the program's goal of creating commercially relevant, investable technologies and a sustainable translational pipeline.
Did the program require cost sharing or matching funds?
No. The announcement indicated there was no cost sharing or matching requirement. However, it strongly encouraged leveraging non-federal resources through partnerships and other mechanisms.
What was the estimated total funding for the opportunity?
NIH estimated total funding at $9,000,000.
What was the award ceiling?
The award ceiling was $1,000,000.
When was the opportunity posted and when did it close?
The opportunity was posted on April 25, 2014. The original and current closing date was June 26, 2014.
Is this funding opportunity still open?
No. The opportunity was archived on July 27, 2014.
What types of organizations were eligible to apply?
Eligibility centered on institutions capable of operating a commercialization and proof-of-concept hub. Eligible applicants included public and state-controlled institutions of higher education and private institutions of higher education. The opportunity also emphasized NIH-recognized categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American and Native American Pacific Islander-Serving Institutions (AANAPISIs).
Were non-U.S. (foreign) institutions eligible to apply?
No. Non-U.S. (foreign) institutions were not eligible to apply.
Were non-U.S. components of U.S. organizations eligible?
No. Non-U.S. components of U.S. organizations were also not eligible.
Could foreign components be involved in any way?
The information provided indicates that foreign components, as defined in the NIH Grants Policy Statement, could be allowed in some circumstances.
What kinds of outcomes was NIH looking for from REACH Hubs?
NIH aimed for measurable translation outcomes: a more reliable pipeline of technologies positioned for licensing, startup formation, partnerships, and later-stage financing, with the ultimate intent that innovations progress toward products that benefit patients.
What is the basic model REACH was trying to establish at institutions?
The model combined (1) systematic technology scouting and selection, (2) targeted proof-of-concept support to reduce risk and define product requirements, (3) integrated expertise across regulatory, reimbursement, IP/legal, business, and project management, and (4) entrepreneurship skills development, while also pushing awardees to build strong public-private partnerships and attract non-federal support.
Browse more opportunities from the same category: Education Environment Food and Nutrition Health Income Security and Social Services
Next opportunity: Planning Grant for Global Infectious Disease Research Training Program (D71)
Previous opportunity: Recovery activities for the Karner Blue Butterfly (KBB) in Concord, NH. CFDA 15.650
USGrants.org Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for RFA OD 14 005
[Watch] how do funding administrators access proposals?
Applicants also applied for:
Applicants who have applied for this opportunity (RFA OD 14 005) also looked into and applied for these:
| Funding Opportunity |
|---|
| Administrative Supplements for Research on Dietary Supplements (Admin Supp) Apply for PAR 14 201 Funding Number: PAR 14 201 Agency: National Institutes of Health Category: Education Environment Food and Nutrition Health Income Security and Social Services Funding Amount: $100,000 |
| Administrative Supplements for Research on Sex/Gender Differences (Admin Supp) Apply for PA 15 034 Funding Number: PA 15 034 Agency: National Institutes of Health Category: Education Environment Food and Nutrition Health Income Security and Social Services Funding Amount: $100,000 |
| Biomedical Data Science Training Coordination Center (U24) Apply for RFA ES 15 004 Funding Number: RFA ES 15 004 Agency: National Institutes of Health Category: Education Environment Food and Nutrition Health Income Security and Social Services Funding Amount: $1,400,000 |
| NIH Pathway to Independence Award (Parent K99/R00) Apply for PA 15 083 Funding Number: PA 15 083 Agency: National Institutes of Health Category: Education Environment Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Supplements to Support Interoperability of NIH Funded Biomedical Data Repositories (Admin Supp) Apply for PA 15 144 Funding Number: PA 15 144 Agency: National Institutes of Health Category: Education Environment Food and Nutrition Health Income Security and Social Services Funding Amount: $300,000 |
| Lasker Clinical Research Scholars Program (Si2/R00) Apply for PAR 15 189 Funding Number: PAR 15 189 Agency: National Institutes of Health Category: Education Environment Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2015 02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR R43/R44) Apply for PA 15 269 Funding Number: PA 15 269 Agency: National Institutes of Health Category: Education Environment Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2015 02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR R41/R42) Apply for PA 15 270 Funding Number: PA 15 270 Agency: National Institutes of Health Category: Education Environment Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Big Data to Knowledge (BD2K) Development of Software Tools and Methods for Biomedical Big Data in Targeted Areas of High Need (U01) Apply for RFA CA 15 017 Funding Number: RFA CA 15 017 Agency: National Institutes of Health Category: Education Environment Food and Nutrition Health Income Security and Social Services Funding Amount: $300,000 |
| Research Supplements to Promote Re Entry into Biomedical and Behavioral Research Careers Apply for PA 08 191 Funding Number: PA 08 191 Agency: National Institutes of Health Category: Education Environment Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Research On Ethical Issues In Human Subjects Research(R03) Apply for PA 06 367 Funding Number: PA 06 367 Agency: National Institutes of Health Category: Education Environment Food and Nutrition Health Income Security and Social Services Funding Amount: $50,000 |
| Research On Ethical Issues In Human Subjects Research (R21) Apply for PA 06 368 Funding Number: PA 06 368 Agency: National Institutes of Health Category: Education Environment Food and Nutrition Health Income Security and Social Services Funding Amount: $200,000 |
| Research Project Grant (Parent R01) Apply for PA 07 070 Funding Number: PA 07 070 Agency: National Institutes of Health Category: Education Environment Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Behavioral and Social Science Research on Understanding and Reducing Health Disparities (R01) Apply for PAR 07 379 Funding Number: PAR 07 379 Agency: National Institutes of Health Category: Education Environment Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Enhancing Zebrafish Research with Research Tools and Techniques (R01) Apply for PAR 08 139 Funding Number: PAR 08 139 Agency: National Institutes of Health Category: Education Environment Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellowships (F31) to Promote Diversity in Health Related Research Apply for PA 07 106 Funding Number: PA 07 106 Agency: National Institutes of Health Category: Education Environment Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Postdoctoral Fellows (F32) Apply for PA 07 107 Funding Number: PA 07 107 Agency: National Institutes of Health Category: Education Environment Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Senior Fellows (F33) Apply for PA 07 172 Funding Number: PA 07 172 Agency: National Institutes of Health Category: Education Environment Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2009 02 Omnibus Solicitation of the NIH, CDC, FDA and ACF for Small Business Innovation Research Grant Applications (Parent SBIR R43/R44) Apply for PA 09 080 Funding Number: PA 09 080 Agency: National Institutes of Health Category: Education Environment Food and Nutrition Health Income Security and Social Services Funding Amount: $100,000 |
| PHS 2009 02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR R41/R42) Apply for PA 09 081 Funding Number: PA 09 081 Agency: National Institutes of Health Category: Education Environment Food and Nutrition Health Income Security and Social Services Funding Amount: $100,000 |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants

Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Subscribe to Leads
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "RFA OD 14 005", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.
