Opportunity Information: Apply for RFA AI 11 003
Apply for RFA AI 11 003
- The National Institutes of Health in the education health income security and social services sector is offering a public funding opportunity titled "NIH/PEPFAR Collaboration for Implementation Science and Impact Evaluation (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.394 Cancer Detection and Diagnosis Research 93.855 Allergy, Immunology and Transplantation Research 93.856 Microbiology and Infectious Diseases Research 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on Apr 5, 2011 and posted on Apr 5, 2011.
- Applicants must submit their applications by Jul 7, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Independent school districts State governments Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Private institutions of higher education County governments City or township governments Native American tribal governments (Federally recognized) For profit organizations other than small businesses.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Foreign (non U.S.) components of U.S. Organizations are allowed.
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Opportunity Summary:
The NIH/PEPFAR Collaboration for Implementation Science and Impact Evaluation (R01) (Funding Opportunity Number RFA-AI-11-003) was a discretionary NIH grant solicitation, posted April 5, 2011, that sought research applications focused on implementation science and impact evaluation to directly inform the US President's Emergency Plan for AIDS Relief (PEPFAR). The central aim was to generate practical, decision-ready evidence on how to deliver HIV prevention, treatment, and care more efficiently and cost effectively at large scale, especially in real-world program settings where PEPFAR operates. Rather than funding basic discovery research, this opportunity emphasized studying how proven interventions are adopted, integrated, optimized, and sustained within health systems and communities, and how different delivery strategies affect outcomes, coverage, quality, and cost.
Projects under this R01 mechanism were intended to help PEPFAR improve program performance by identifying what implementation approaches work best, for whom, and under what conditions. The phrase "implementation science and impact evaluation" signals an expectation that applicants would assess both the mechanics of delivery (for example, service models, workforce strategies, supply chain approaches, task shifting, integration with other services, or adherence and retention supports) and the measurable effects of these approaches on HIV-related outcomes and program efficiency. In practice, competitive proposals would typically be designed around real program questions, use rigorous evaluation methods appropriate for large-scale public health programs, and produce findings that can be translated into policy or operational changes.
The funding instrument was a grant using the R01 activity code, which generally supports substantial, hypothesis-driven research projects with clearly defined aims, strong study design, and an experienced investigative team. The opportunity fell under multiple NIH-related activity categories listed in the source data (Education; Health; Income Security and Social Services) and referenced several CFDA program areas, reflecting the cross-cutting nature of HIV implementation research. The CFDA numbers included 93.242 (Mental Health Research Grants), 93.273 (Alcohol Research Programs), 93.279 (Drug Abuse and Addiction Research Programs), 93.394 (Cancer Detection and Diagnosis Research), 93.855 (Allergy, Immunology and Transplantation Research), 93.856 (Microbiology and Infectious Diseases Research), and 93.865 (Child Health and Human Development Extramural Research). This spread suggests the solicitation was positioned to attract interdisciplinary work where HIV service delivery intersects with behavioral health, substance use, comorbidities, maternal and child health, and broader health system concerns.
Eligibility was broad and included a wide range of domestic and international organizations, consistent with the global footprint of PEPFAR and the operational nature of implementation research. Eligible applicants included federal, state, local, and tribal governments (including federally recognized tribal governments), special district governments, public housing authorities/Indian housing authorities, public and private institutions of higher education, independent school districts, nonprofits with and without 501(c)(3) status, small businesses, and for-profit organizations other than small businesses. Additional eligible categories explicitly listed included faith-based and community-based organizations, historically Black colleges and universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities (TCCUs), regional organizations, US territories or possessions, and non-domestic (foreign) entities. Foreign (non-US) components of US organizations were also allowed, which is particularly relevant for studies embedded in PEPFAR-supported programs outside the United States.
No cost sharing or matching was required, lowering barriers for applicants who might otherwise struggle to provide non-federal contributions. The application timeline shows the announcement was created and posted on April 5, 2011, with an original and current closing date of July 7, 2011, and an archive date of August 7, 2011, indicating it was a time-limited request for applications rather than an ongoing program announcement.
The sponsoring agency was the National Institutes of Health, working in collaboration with the Office of the Global AIDS Coordinator, the office responsible for overseeing PEPFAR. Applicants were directed to the full announcement via the NIH grants guide link (http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-11-003.html). For technical access issues, the contact listed was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV, which is typical for help with the electronic posting rather than scientific programmatic questions.
Overall, this grant opportunity was designed to fund rigorous, field-relevant research that could help PEPFAR refine delivery strategies, improve quality and reach of HIV services, and achieve better outcomes per dollar spent, using implementation science methods and impact evaluation approaches that match the complexity of operating large HIV programs in diverse health system contexts.
FAQs: NIH/PEPFAR Collaboration for Implementation Science and Impact Evaluation (R01) - RFA-AI-11-003
What is this funding opportunity?
This opportunity was the NIH/PEPFAR Collaboration for Implementation Science and Impact Evaluation (R01), Funding Opportunity Number RFA-AI-11-003. It was a discretionary NIH grant solicitation posted on April 5, 2011, seeking research applications that use implementation science and impact evaluation to directly inform the US President's Emergency Plan for AIDS Relief (PEPFAR).
What was the main goal of the solicitation?
The central goal was to generate practical, decision-ready evidence on how to deliver HIV prevention, treatment, and care more efficiently and cost effectively at large scale, particularly in real-world program settings where PEPFAR operates.
What types of research were emphasized?
The solicitation emphasized implementation science and impact evaluation research focused on how proven HIV interventions are adopted, integrated, optimized, and sustained within health systems and communities, and how different delivery strategies affect outcomes, coverage, quality, and cost.
Was this opportunity focused on basic or discovery research?
No. The opportunity emphasized studying the delivery and performance of proven interventions in real-world settings rather than funding basic discovery research.
What does "implementation science and impact evaluation" mean in the context of this RFA?
It signals an expectation that applicants would evaluate both (1) how services are delivered (the mechanics and strategies of implementation) and (2) the measurable effects of those strategies on HIV-related outcomes and on program efficiency (including cost effectiveness).
What kinds of implementation topics or strategies were relevant?
The description highlights examples such as service models, workforce strategies, supply chain approaches, task shifting, integration with other services, and adherence and retention supports.
What kinds of outcomes were proposals expected to assess?
Proposals were expected to assess measurable effects on HIV-related outcomes and on program efficiency, including impacts on coverage, quality, cost, and overall performance in large-scale public health program settings.
What was PEPFAR expected to gain from the funded projects?
Projects were intended to help PEPFAR improve program performance by identifying what implementation approaches work best, for whom, and under what conditions, producing findings that could translate into policy or operational changes.
What grant mechanism was used?
The funding instrument was an NIH grant using the R01 activity code, which generally supports substantial, hypothesis-driven research projects with clearly defined aims, strong study design, and an experienced investigative team.
What activity categories were associated with the opportunity?
The source information listed multiple NIH-related activity categories: Education; Health; and Income Security and Social Services. This reflects the cross-cutting nature of HIV implementation research and program delivery.
Which CFDA program areas were referenced?
The CFDA numbers referenced were 93.242 (Mental Health Research Grants), 93.273 (Alcohol Research Programs), 93.279 (Drug Abuse and Addiction Research Programs), 93.394 (Cancer Detection and Diagnosis Research), 93.855 (Allergy, Immunology and Transplantation Research), 93.856 (Microbiology and Infectious Diseases Research), and 93.865 (Child Health and Human Development Extramural Research).
What does the range of CFDA numbers suggest about the intended scope?
The spread suggests the solicitation aimed to attract interdisciplinary work where HIV service delivery intersects with behavioral health, substance use, comorbidities, maternal and child health, and broader health system concerns.
Who was eligible to apply?
Eligibility was broad and included domestic and international organizations. Eligible applicants included federal, state, local, and tribal governments (including federally recognized tribal governments), special district governments, public housing authorities/Indian housing authorities, public and private institutions of higher education, independent school districts, nonprofits with and without 501(c)(3) status, small businesses, and for-profit organizations other than small businesses.
Were faith-based and community-based organizations eligible?
Yes. Faith-based and community-based organizations were explicitly listed as eligible applicants.
Were minority-serving institutions eligible?
Yes. The eligibility list explicitly included historically Black colleges and universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and tribally controlled colleges and universities (TCCUs).
Could foreign organizations apply?
Yes. Non-domestic (foreign) entities were eligible, consistent with PEPFAR's global footprint.
Were foreign components of US organizations allowed?
Yes. Foreign (non-US) components of US organizations were allowed, which is relevant for studies embedded in PEPFAR-supported programs outside the United States.
Were US territories or possessions included in eligibility?
Yes. US territories or possessions were explicitly listed among eligible categories.
Was cost sharing or matching required?
No. The opportunity stated that no cost sharing or matching was required.
When was the opportunity posted?
The announcement was created and posted on April 5, 2011.
What was the application deadline?
The original and current closing date was July 7, 2011.
Was this a time-limited solicitation?
Yes. It was a time-limited request for applications, reflected by the single closing date and an archive date of August 7, 2011.
Who sponsored the opportunity?
The sponsoring agency was the National Institutes of Health (NIH), working in collaboration with the Office of the Global AIDS Coordinator, the office responsible for overseeing PEPFAR.
Where could applicants find the full announcement?
Applicants were directed to the NIH grants guide page at: http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-11-003.html
Who was the listed contact for technical access issues?
The contact for technical access issues was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
What kind of support was the listed contact intended to provide?
The contact was described as typical for help with electronic posting or technical access issues, rather than scientific or programmatic questions.
What characteristics were implied for competitive proposals?
Based on the description, competitive proposals would typically be designed around real program questions, use rigorous evaluation methods appropriate for large-scale public health programs, and produce findings that can be translated into policy or operational changes.
What is meant by producing "decision-ready evidence"?
In this context, it refers to evidence that is practical and directly useful for operational or policy decision-making within PEPFAR-supported HIV programs, including how to improve efficiency, quality, reach, and outcomes per dollar spent.
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