Opportunity Information: Apply for PAR 09 246

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "NIMH Career Transition Award for Intramural Investigators (K22)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.281 Mental Health Research Career/Scientist Development Awards 93.855 Allergy, Immunology and Transplantation Research 93.856 Microbiology and Infectious Diseases Research.
  • This funding opportunity was created on Jul 31, 2009 and posted on Jul 31, 2009.
  • Applicants must submit their applications by Sep 7, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) .
Apply for PAR 09 246

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Opportunity Summary:

The NIMH Career Transition Award for Intramural Investigators (K22) is a National Institute of Mental Health program designed to help established NIMH intramural scientists move from the NIMH Division of Intramural Research Programs (DIRP) into research positions in the extramural community, most commonly at domestic academic institutions. The core idea is to provide a structured bridge for investigators who already have a strong record of high-quality, mental health-relevant research and who are ready to take the next step into an externally based faculty or equivalent research appointment. In practical terms, it is meant to reduce the career and funding disruption that can happen when a federal intramural investigator transitions to an outside institution, while also positioning that investigator to launch an independent, sustainable extramural research program.

This opportunity uses the NIH Career Transition (K22) grant mechanism and is organized around a two-phase process. The first phase is an application prepared and submitted while the candidate is still in a tenured or tenure-track position within NIMH intramural laboratories. Phase 1 is the portion that undergoes peer review for scientific merit, and that review outcome is the main factor determining whether NIMH intends to support the candidate. Importantly, while Phase 1 is reviewed, the actual award is not made at that point. Instead, a strong Phase 1 review results in a written indication of NIMH commitment to make an award contingent on the successful completion of the transition requirements.

After a fundable Phase 1 score, the candidate is given up to 18 months to find and secure an appropriate extramural research position at a domestic academic institution and to negotiate a startup package. Once those negotiations are completed and the position is lined up, the candidate submits the Phase 2 application. Phase 2 is the application that is actually awarded, and it activates the K22 support at the new extramural institution. The K22 provides up to three years of support timed to the transition, functioning as a launch pad for the investigator to establish an independent program in their new setting.

Administratively, this is a discretionary grant funding opportunity issued by the National Institutes of Health, with the FOA identifier PAR-09-246 and the title "NIMH Career Transition Award for Intramural Investigators (K22)." It was originally posted on July 31, 2009, and the last listed closing date was September 7, 2012, with an archive date of October 8, 2012, indicating it is not a current open competition under that specific announcement. It falls under NIH activity categories tied to education and health, and it is associated with CFDA numbers including 93.281 (Mental Health Research Career/Scientist Development Awards), as well as 93.855 and 93.856 (areas related to immunology/transplantation and microbiology/infectious diseases), reflecting the broader NIH cataloging and potential intersections with mental health research rather than limiting the program strictly to one narrow scientific domain.

Eligibility, as listed in the announcement metadata, includes a wide set of institution types that can serve as applicant organizations for the extramural phase. These include public and state-controlled institutions of higher education, private institutions of higher education, certain nonprofit organizations (including 501(c)(3) nonprofits and some non-501(c)(3) nonprofits other than institutions of higher education), and for-profit organizations other than small businesses. The eligibility listing also explicitly includes institutions serving specific populations, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian Serving Institutions. Cost sharing or matching is not required, which matters because it reduces institutional financial barriers and keeps the focus on the candidate's merit, research plan, and the transition environment.

Overall, the K22 described here is best understood as a targeted transition mechanism for NIMH intramural investigators who have already demonstrated research excellence and are ready to move into the extramural ecosystem. It relies on rigorous peer review at Phase 1 to establish scientific credibility, then uses Phase 2 to formalize the move to an outside institution once the investigator has secured an appropriate position and startup support, with up to three years of K22 funding intended to stabilize and accelerate the investigator's independent research trajectory during that critical transition period.

Frequently Asked Questions (FAQs): NIMH Career Transition Award for Intramural Investigators (K22) - PAR-09-246

What is the NIMH Career Transition Award for Intramural Investigators (K22)?

The NIMH Career Transition Award for Intramural Investigators (K22) is an NIH/NIMH program intended to help established NIMH intramural scientists transition from the NIMH Division of Intramural Research Programs (DIRP) into research positions in the extramural community, most commonly at domestic academic institutions. It is designed to reduce career and funding disruption during the move and to support the launch of an independent, sustainable extramural research program.

Who is this K22 designed for?

This opportunity is described as being for established NIMH intramural scientists who already have a strong track record of high-quality, mental health-relevant research and who are ready to move from NIMH intramural laboratories into an externally based faculty or equivalent research appointment.

What is the overall purpose of the program?

The program is meant to provide a structured bridge from an NIMH intramural position to an extramural research position. The intent is to (1) minimize disruption that can occur when leaving a federal intramural environment and (2) position the investigator to quickly establish an independent extramural research program.

What grant mechanism does this opportunity use?

It uses the NIH Career Transition (K22) grant mechanism.

How is the K22 structured (Phase 1 vs Phase 2)?

The opportunity is organized as a two-phase process:

  • Phase 1: Prepared and submitted while the candidate is still in a tenured or tenure-track position within NIMH intramural laboratories. Phase 1 is the portion that undergoes peer review for scientific merit.
  • Phase 2: Submitted after the candidate has secured an appropriate extramural position and negotiated a startup package. Phase 2 is the application that is actually awarded and activates the K22 support at the new extramural institution.

When is Phase 1 submitted?

Phase 1 is submitted while the candidate is still employed in a tenured or tenure-track role within NIMH intramural laboratories (DIRP).

Which phase is peer reviewed?

Phase 1 undergoes peer review for scientific merit, and the review outcome is the main factor in determining whether NIMH intends to support the candidate.

Does a strong Phase 1 score mean the award is made immediately?

No. Even with a strong (fundable) Phase 1 review, the award is not made at that point. Instead, a strong Phase 1 outcome leads to a written indication of NIMH commitment to make an award, contingent upon successfully completing the transition requirements.

What happens after a fundable Phase 1 score?

After a fundable Phase 1 score, the candidate has up to 18 months to find and secure an appropriate extramural research position at a domestic academic institution and to negotiate a startup package. Once those steps are completed, the candidate submits the Phase 2 application.

How long does the candidate have to complete the transition?

The candidate is given up to 18 months after a fundable Phase 1 score to secure an extramural position and complete startup negotiations, before submitting Phase 2.

What is the role of the extramural institution in Phase 2?

Phase 2 is submitted once an extramural research position is lined up and a startup package has been negotiated. The K22 support is then activated at the new extramural institution through the Phase 2 award.

How much support does the K22 provide, and for how long?

The K22 provides up to three years of support, timed to the investigator’s transition and intended to serve as a launch pad for establishing an independent research program in the new extramural setting.

Where is the investigator expected to move for the extramural phase?

The program is described as supporting a move into the extramural community, most commonly at domestic academic institutions. The Phase 2 transition described here centers on securing an extramural position at a domestic academic institution.

Is this a current, open funding opportunity?

Based on the information provided, this specific announcement (FOA identifier PAR-09-246) is archived and not a current open competition under that announcement. It was originally posted on July 31, 2009, with the last listed closing date of September 7, 2012, and an archive date of October 8, 2012.

What is the FOA identifier and title for this opportunity?

The FOA identifier is PAR-09-246, and the title is "NIMH Career Transition Award for Intramural Investigators (K22)."

Which agency and institute issue this opportunity?

It is a discretionary grant funding opportunity issued by the National Institutes of Health (NIH), specifically through the National Institute of Mental Health (NIMH).

What kinds of organizations can serve as applicant institutions for the extramural phase?

The eligibility metadata lists a broad range of institution types that can serve as applicant organizations for the extramural phase, including:

  • Public and state-controlled institutions of higher education
  • Private institutions of higher education
  • Nonprofit organizations, including 501(c)(3) nonprofits and certain non-501(c)(3) nonprofits other than institutions of higher education
  • For-profit organizations other than small businesses

Are minority-serving institutions included as eligible applicants?

Yes. The eligibility listing explicitly includes institutions such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), and Alaska Native and Native Hawaiian Serving Institutions.

Is cost sharing or matching required?

No. Cost sharing or matching is not required for this opportunity.

What kinds of research areas are associated with this opportunity?

The program is described as supporting investigators with high-quality, mental health-relevant research. The opportunity is also associated with CFDA numbers including 93.281 (Mental Health Research Career/Scientist Development Awards) as well as 93.855 and 93.856 (areas related to immunology/transplantation and microbiology/infectious diseases). This suggests broader NIH cataloging and potential intersections with mental health research, rather than restricting the program to a single narrow scientific domain.

What is the NIMH DIRP, and why does it matter for eligibility?

The NIMH Division of Intramural Research Programs (DIRP) is the intramural (inside NIH) research environment the candidate is transitioning from. Phase 1 is specifically prepared and submitted while the candidate is still in a tenured or tenure-track position within NIMH intramural laboratories, making DIRP status central to the described candidate pathway.

What is the main benefit of this K22 during a transition?

The core benefit described is stability during a high-risk career move: the K22 is intended to reduce disruption when transitioning out of the federal intramural setting and to provide up to three years of support to accelerate the investigator’s independent extramural research trajectory in the new institution.

What triggers the start of K22 funding at the new institution?

K22 funding is activated through the Phase 2 application, after the candidate has secured an extramural position and negotiated a startup package. Phase 2 is the portion that is actually awarded.

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