Opportunity Information: Apply for RFA MD 12 004
Apply for RFA MD 12 004
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIMHD Basic and Applied Biomedical Research on Minority Health and Health Disparities (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.307 Minority Health and Health Disparities Research.
- This funding opportunity was created on Feb 14, 2012 and posted on Feb 14, 2012.
- Applicants must submit their applications by Jun 11, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $250,000.00 in funding.
- Eligible applicants include: Special district governments Public housing authorities/Indian housing authorities Independent school districts State governments City or township governments For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The NIMHD Basic and Applied Biomedical Research on Minority Health and Health Disparities (R01) funding opportunity (RFA-MD-12-004) is a National Institutes of Health grant program run by the National Institute on Minority Health and Health Disparities (NIMHD). It is designed to support innovative, hypothesis-driven research that deepens scientific understanding of why certain diseases and adverse health outcomes disproportionately affect racial and ethnic minority groups and other health disparity populations, and to help translate that knowledge into therapies, interventions, or clinical approaches that can measurably reduce or eliminate those disparities. The emphasis is on strong biomedical research projects that either uncover fundamental mechanisms driving disparities or connect biological discoveries to real-world clinical impact.
The FOA highlights two broad, complementary scientific tracks. First, it invites biological and genetic research aimed at identifying disease mechanisms, molecular pathways, and biological processes that influence health outcomes specifically within minority and health disparity populations. This includes studies of etiology and physiology, genetic risk factors, and molecular or cellular pathways that may differ across populations or interact with distinct environmental and social exposures. Second, it seeks clinical and translational research that bridges basic science with effective treatment or clinical practice, meaning projects that move discoveries toward improved diagnosis, prevention, treatment selection, or clinical implementation in ways that are relevant to disparity-affected groups. Across both tracks, NIMHD signals particular interest in research on gene-environment interactions, pharmacogenomics, personalized or precision medicine approaches, and other mechanistic work that can explain differential risks, progression patterns, or treatment responses among health disparity populations.
The overarching goal is not only to generate new knowledge, but to generate knowledge that is clearly tied to reducing inequities in health outcomes. In practical terms, competitive applications would be expected to make a compelling case that the biological questions being asked matter for disparity populations, that the population being studied is appropriate for answering those questions, and that the work has a credible pathway to improving health outcomes through better understanding of mechanisms, better therapeutic targeting, better clinical decision-making, or more effective interventions tailored to populations experiencing disproportionate burden.
From an administrative standpoint, this is a discretionary grant opportunity using the NIH R01 research project grant mechanism, categorized under Health, with CFDA 93.307 (Minority Health and Health Disparities Research). The FOA listed an estimated total funding amount of $2,000,000 and an award ceiling of $250,000 (as provided in the source information). It did not require cost sharing or matching. The opportunity was posted and created on February 14, 2012, with an original and final closing date of June 11, 2012, and it was archived on July 12, 2012.
Eligibility is broad and includes many types of U.S.-based organizations and governmental entities. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including those with and without 501(c)(3) status, excluding institutions of higher education where applicable), for-profit organizations (including small businesses and other for-profits), state governments, county governments, city or township governments, special district governments, independent school districts, public housing authorities/Indian housing authorities, and federally recognized Native American tribal governments, as well as other tribal organizations. The FOA also explicitly includes Alaska Native and Native Hawaiian Serving Institutions, Hispanic Serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. Non-U.S. (foreign) institutions and non-U.S. components of U.S. organizations were not eligible to apply, although foreign components, as defined by NIH policy, were allowed.
For applicants seeking the original announcement details, the FOA link was provided through the NIH Grants Guide at http://grants.nih.gov/grants/guide/rfa-files/RFA-MD-12-004.html, with technical access support routed to the NIH Office of Extramural Research (OER) webmaster (FBOWebmaster@OD.NIH.GOV).
Frequently Asked Questions (FAQs)
1) What is the name and number of this funding opportunity?
This opportunity is titled "Basic and Applied Biomedical Research on Minority Health and Health Disparities (R01)" and is identified as RFA-MD-12-004.
2) Which agency runs this grant program?
The program is run by the National Institutes of Health (NIH) through the National Institute on Minority Health and Health Disparities (NIMHD).
3) What type of grant mechanism is used?
The funding uses the NIH R01 research project grant mechanism.
4) What is the main purpose of this FOA?
The purpose is to support innovative, hypothesis-driven biomedical research that explains why certain diseases and adverse outcomes disproportionately affect racial and ethnic minority groups and other health disparity populations, and to translate that understanding into therapies, interventions, or clinical approaches that can measurably reduce or eliminate disparities.
5) What kinds of research does NIMHD emphasize in this FOA?
The FOA emphasizes strong biomedical research projects that either (a) uncover fundamental biological mechanisms driving disparities or (b) connect biological discoveries to real-world clinical impact for populations experiencing disproportionate health burdens.
6) What are the two broad scientific tracks described in the FOA?
The FOA describes two complementary tracks: (1) biological and genetic research focused on disease mechanisms and processes in minority and health disparity populations, and (2) clinical and translational research that bridges basic science discoveries to improved treatment or clinical practice relevant to disparity-affected groups.
7) What is included under the biological and genetic research track?
This track includes research aimed at identifying etiology and physiology, genetic risk factors, and molecular or cellular pathways that influence health outcomes in minority and health disparity populations, including situations where pathways differ across populations or interact with distinct environmental and social exposures.
8) What is included under the clinical and translational research track?
This track includes research that moves basic science discoveries toward improved diagnosis, prevention, treatment selection, or clinical implementation, specifically in ways that are relevant to groups affected by health disparities.
9) Are gene-environment interactions within scope?
Yes. NIMHD signaled particular interest in gene-environment interactions as part of mechanistic work that can explain differential risks, progression patterns, or treatment responses among health disparity populations.
10) Does the FOA encourage pharmacogenomics and precision medicine approaches?
Yes. The FOA highlights interest in pharmacogenomics, personalized or precision medicine approaches, and related mechanistic research that can clarify differential treatment response or disease risk among health disparity populations.
11) What makes an application competitive based on the FOA description?
Based on the FOA summary provided, competitive applications would be expected to clearly justify why the biological questions matter for disparity populations, demonstrate that the study population is appropriate to answer those questions, and present a credible pathway to improving health outcomes (for example through better mechanistic understanding, therapeutic targeting, clinical decision-making, or more effective interventions tailored to populations experiencing disproportionate burden).
12) Is this opportunity focused only on generating new knowledge, or also on real-world impact?
It is focused on both. The FOA stresses generating new knowledge and tying that knowledge to reducing inequities in health outcomes through translational relevance and measurable potential to reduce or eliminate disparities.
13) What is the CFDA number associated with this program?
The CFDA is 93.307 (Minority Health and Health Disparities Research).
14) What category is this opportunity listed under?
It is categorized under Health.
15) What was the estimated total funding amount?
The FOA listed an estimated total funding amount of $2,000,000.
16) What was the award ceiling listed in the provided information?
The award ceiling was listed as $250,000 (as provided in the source information).
17) Is cost sharing or matching required?
No. The opportunity did not require cost sharing or matching.
18) When was the opportunity posted and created?
The opportunity was posted and created on February 14, 2012.
19) What were the application due dates?
The original closing date and the final closing date were both June 11, 2012.
20) Is this funding opportunity still active?
No. The opportunity was archived on July 12, 2012.
21) Who was eligible to apply?
Eligibility was broad and included many U.S.-based organizations and governmental entities, including public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (with and without 501(c)(3) status, excluding institutions of higher education where applicable), for-profit organizations (including small businesses), and various levels of government (state, county, city or township, special district), among others listed in the FOA summary.
22) Are tribal governments and tribal organizations eligible?
Yes. Federally recognized Native American tribal governments and other tribal organizations were included as eligible applicants.
23) Are specific institution types like HBCUs and HSIs included?
Yes. The FOA explicitly includes Alaska Native and Native Hawaiian Serving Institutions, Hispanic Serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).
24) Are faith-based or community-based organizations eligible?
Yes. The FOA explicitly includes faith-based or community-based organizations.
25) Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions were included as eligible applicants.
26) Are non-U.S. (foreign) institutions allowed to apply?
No. Non-U.S. (foreign) institutions and non-U.S. components of U.S. organizations were not eligible to apply.
27) Are foreign components allowed under NIH policy?
Yes. While foreign institutions could not apply, foreign components (as defined by NIH policy) were allowed.
28) Where can applicants find the original FOA announcement?
The FOA was available through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/rfa-files/RFA-MD-12-004.html
29) Who should be contacted for technical access support related to the FOA link?
Technical access support was routed to the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
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