Opportunity Information: Apply for RFA NS 14 001
Apply for RFA NS 14 001
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NINDS Clinical Trial Methods in Clinical Neurological Disorders Course (R25)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders.
- This funding opportunity was created on Oct 18, 2013 and posted on Jul 10, 2013.
- Applicants must submit their applications by Nov 1, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $462,500.00 to eligible and selected applicants.
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal governments (Federally recognized) Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education State governments Special district governments For profit organizations other than small businesses City or township governments County governments Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The NINDS Clinical Trial Methods in Clinical Neurological Disorders Course (R25) grant opportunity (Funding Opportunity Number RFA-NS-14-001) is a discretionary NIH grant mechanism designed to strengthen how clinical trials are planned, run, and interpreted in neurology. Its central goal is to improve the reliability and real-world effectiveness of clinical trials by supporting a structured training course that helps investigators who are new to clinical trials gain practical, up-to-date skills. In other words, this FOA is not mainly about funding a specific clinical trial; it is about funding a high-quality educational program that prepares researchers and clinician-investigators to design and conduct better neurological clinical trials, using sound methods and avoiding common sources of bias, inefficiency, and poor reproducibility.
The opportunity is administered by the National Institutes of Health, specifically within the mission area of the National Institute of Neurological Disorders and Stroke (NINDS), and it falls under the health funding activity category with CFDA number 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders). The emphasis on a "Clinical Trial Methods" course signals a focus on training content such as clinical trial design choices, endpoint selection, randomization and blinding, operational execution, data quality, monitoring, ethical and regulatory considerations, and interpretation of outcomes in neurological disorders. The overarching intent is to build a stronger pipeline of investigators who can contribute to more rigorous and informative trials, ultimately improving evidence generation for treatments in neurology.
This FOA uses the grant funding instrument type and does not require cost sharing or matching. The estimated total funding amount listed for the opportunity is $462,500, indicating that NINDS expected to support course-based training activity at a meaningful scale, but within a defined budget range typical for education and training infrastructure rather than large research programs. The announcement was posted on July 10, 2013, created on October 18, 2013, and had an original closing date of October 9, 2013, later extended to a current closing date of November 1, 2013. The archive date is December 1, 2013, meaning it is a past opportunity, but the details remain useful as a model for similar R25 training announcements.
Eligibility is broad across many types of U.S.-based organizations, reflecting the idea that strong clinical trial training programs can be housed in universities, academic medical centers, nonprofits, government entities, and even certain for-profit organizations, as long as they can credibly deliver high-quality education in clinical trial methods relevant to neurological disorders. Eligible applicants listed include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits with and without 501(c)(3) status, small businesses, for-profit organizations (other than small businesses), and a range of government entities such as state, county, city or township governments, special district governments, and public housing authorities/Indian housing authorities. The FOA also explicitly recognizes additional eligible applicant categories, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISISs), among others. Faith-based or community-based organizations and eligible federal agencies are also included, which underscores NIH's willingness to support diverse institutional settings when the training mission is strong.
At the same time, the opportunity is limited to domestic applicants in terms of who can apply directly: non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply, and non-domestic components of U.S. organizations are not eligible to apply. However, the FOA allows foreign components as defined in the NIH Grants Policy Statement, meaning a U.S. applicant organization could potentially include certain foreign collaborations or elements when justified and compliant with NIH policy, even though the applicant institution itself must be eligible and U.S.-based.
For applicants or interested parties seeking full details, the FOA points to the NIH Grants Guide listing (http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-14-001.html). The provided contact pathway is the NIH Office of Extramural Research (OER) Webmaster support (FBOWebmaster@OD.NIH.GOV) for issues accessing the announcement electronically or linking to the funding opportunity page, which is typical for older archived FOAs that were distributed through legacy federal systems.
Overall, the RFA-NS-14-001 opportunity is best understood as NINDS support for a dedicated, formal training course in clinical trial methodology tailored to clinical neurological disorders, with the explicit intention of improving trial quality across the field by better preparing the next generation of clinical trial investigators.
Frequently Asked Questions (FAQs)
What is the NINDS Clinical Trial Methods in Clinical Neurological Disorders Course (R25) opportunity?
This is an NIH/NINDS discretionary grant opportunity (R25) intended to support a structured training course focused on clinical trial methods in clinical neurological disorders. The purpose is to strengthen how neurological clinical trials are planned, conducted, and interpreted by training investigators who are new to clinical trials.
What is the Funding Opportunity Number (FOA number) for this grant?
The Funding Opportunity Number is RFA-NS-14-001.
Is this grant meant to fund an actual clinical trial?
No. The central emphasis is not funding a specific clinical trial. It is funding a high-quality educational and training program (a course) that prepares researchers and clinician-investigators to design and conduct better neurological clinical trials using sound methods and avoiding common sources of bias, inefficiency, and poor reproducibility.
Which NIH institute administers this opportunity?
The opportunity is administered within the National Institutes of Health (NIH), specifically aligned to the mission area of the National Institute of Neurological Disorders and Stroke (NINDS).
What is the CFDA number and activity category associated with this opportunity?
The opportunity is listed under CFDA 93.853, "Extramural Research Programs in the Neurosciences and Neurological Disorders," and falls under the health funding activity category.
What is the main goal of the funded course?
The main goal is to improve the reliability and real-world effectiveness of neurological clinical trials by providing investigators new to clinical trials with practical, up-to-date skills for designing, running, and interpreting trials.
What kinds of topics is the course expected to cover?
Based on the FOA description, the course focus includes clinical trial design choices, endpoint selection, randomization and blinding, operational execution, data quality, monitoring, ethical and regulatory considerations, and interpretation of outcomes in neurological disorders.
What type of funding instrument is used?
This opportunity uses the grant funding instrument type.
Does this FOA require cost sharing or matching funds?
No. Cost sharing or matching is not required.
What is the estimated total funding amount for the opportunity?
The estimated total funding amount listed is $462,500.
When was the announcement posted and when did it close?
The announcement was posted on July 10, 2013. It had an original closing date of October 9, 2013, and was later extended to a current closing date of November 1, 2013.
Is this an active funding opportunity?
No. The FOA is an archived, past opportunity. The archive date is December 1, 2013. Even though it is no longer open, the information can still be useful as a model for similar R25 training announcements.
Who is eligible to apply?
Eligibility is broad across many U.S.-based organizations. The FOA lists eligible applicants such as public and state-controlled institutions of higher education, private institutions of higher education, nonprofits with and without 501(c)(3) status, small businesses, for-profit organizations (other than small businesses), and a range of government entities (state, county, city or township, special district governments, and public housing authorities/Indian housing authorities).
Are minority-serving and special-designation institutions included in eligibility?
Yes. The FOA explicitly recognizes additional eligible applicant categories, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), among others.
Can faith-based or community-based organizations apply?
Yes. Faith-based or community-based organizations are included among eligible applicants, as described.
Are federal agencies eligible to apply?
Yes. Eligible federal agencies are included in the list of eligible applicants.
Are foreign (non-U.S.) institutions eligible to apply directly?
No. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply directly, and non-domestic components of U.S. organizations are not eligible to apply.
Are any foreign components allowed at all?
Yes. The FOA allows foreign components as defined in the NIH Grants Policy Statement. This means a U.S. applicant organization could potentially include certain foreign collaborations or elements when justified and compliant with NIH policy, even though the applicant institution itself must be U.S.-based and eligible.
Where can applicants find the full FOA text?
The FOA points to the NIH Grants Guide listing at: http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-14-001.html
Who should be contacted for problems accessing the announcement online?
For issues accessing the announcement electronically or linking to the funding opportunity page, the FOA provides the NIH Office of Extramural Research (OER) Webmaster contact: FBOWebmaster@OD.NIH.GOV
What is the broader purpose of NINDS supporting this type of course?
The stated intent is to build a stronger pipeline of investigators who can contribute to more rigorous and informative clinical trials in neurology, ultimately improving evidence generation for treatments in neurological disorders.
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