Opportunity Information: Apply for PAR 08 236
Apply for PAR 08 236
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "NINDS Cooperative Program in Translational Research Resource Centers (U24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders.
- This funding opportunity was created on Dec 3, 2008 and posted on Dec 3, 2008.
- Applicants must submit their applications by Sep 7, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Independent school districts City or township governments Native American tribal governments (Federally recognized) Special district governments County governments Public housing authorities/Indian housing authorities Small businesses For profit organizations other than small businesses State governments Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The NINDS Cooperative Program in Translational Research Resource Centers (U24) (Funding Opportunity Number PAR-08-236) is a National Institutes of Health funding opportunity designed to strengthen the practical infrastructure needed to move new neurology therapeutics toward the clinic. Rather than primarily funding hypothesis-driven basic research, this program focuses on milestone-driven, resource-related projects that generate tangible products and services used in preclinical testing. In plain terms, NINDS is looking to support centers or groups that can build, operate, and deliver specialized capabilities that help researchers and developers test potential neurological treatments before they reach human trials.
This opportunity uses the U24 Resource-Related Research Project Cooperative Agreement mechanism. A U24 cooperative agreement typically signals a more hands-on partnership between the awardees and the NIH compared with a standard research grant, meaning NINDS program staff are expected to have substantial involvement in the funded activities. The emphasis on milestones also indicates that applicants are expected to propose clear, measurable deliverables and timelines, and progress is likely to be tracked against predefined performance goals to ensure that the funded resources remain useful, reliable, and aligned with translational needs in neurology.
The core purpose is to provide neurology-specific preclinical testing support, which can include services, tools, standardized methods, or other enabling resources that reduce bottlenecks in translational research. The announcement frames these as products and services required for preclinical testing of new therapeutics, suggesting a strong orientation toward practical development steps such as assay development, validation platforms, specialized animal or cellular models, biomarkers, pharmacology/toxicology-related capabilities, data resources, or other kinds of shared translational infrastructure that multiple projects or stakeholders could rely on. The key is that the work is resource-oriented and directly supports the preclinical phase for neurological therapeutics, rather than being purely exploratory science.
Funding size, project scope, and award duration were intentionally left flexible because applications could vary widely in what they propose to build or provide. As a result, NINDS did not specify a fixed number of awards or a standard budget level. Instead, the total funding distributed and the number of awards would depend on the quality of the applications, how long the proposed work would take, and the costs required to carry out the resource center activities. There is no cost-sharing or matching requirement listed for this program.
Eligibility was broad and included many types of domestic organizations across nonprofit, academic, government, and private-sector categories. Eligible applicants included nonprofits with and without 501(c)(3) status, public and private institutions of higher education, small businesses, and for-profit organizations other than small businesses, as well as a range of government entities (state governments, county governments, city or township governments, special district governments, independent school districts, and certain housing authorities). Tribal and indigenous-serving organizations were also included, spanning federally recognized tribal governments, tribal organizations that are not federally recognized, tribally controlled colleges and universities, and regional organizations. The eligibility listing also explicitly included Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities, faith-based or community-based organizations, and U.S. territories or possessions, along with eligible agencies of the federal government.
Administratively, this was a discretionary grant opportunity under the NIH, categorized under health, and associated with CFDA number 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders). The opportunity was posted on December 3, 2008, and the original and final closing date was September 7, 2011, after which it was archived on October 8, 2011. The full announcement was hosted through the NIH Grants Guide (linked in the notice), and NIH provided contact support through the NIH Office of Extramural Research web team for access or linking issues.
Overall, this FOA represents an NIH/NINDS effort to fund collaborative, deliverable-focused translational infrastructure in neurology, with projects expected to operate as shared resources and to be managed under cooperative agreement terms with milestone accountability, flexible budgets based on scope, and a wide pool of eligible applicant organizations.
FAQs: NINDS Cooperative Program in Translational Research Resource Centers (U24) (PAR-08-236)
What is the PAR-08-236 funding opportunity?
PAR-08-236 is a National Institutes of Health (NIH) funding opportunity from the National Institute of Neurological Disorders and Stroke (NINDS) for the Cooperative Program in Translational Research Resource Centers (U24). It is designed to strengthen the practical infrastructure needed to move new neurology therapeutics toward clinical testing by supporting centers or groups that provide specialized preclinical testing capabilities.
What is the main goal of this program?
The main goal is to support milestone-driven, resource-related projects that produce tangible products and services used in preclinical testing of potential neurological treatments. The focus is on reducing bottlenecks in translational neurology by building and operating shared resources that others can rely on.
Is this opportunity focused on basic research or applied resource development?
This program is oriented toward resource development and delivery rather than primarily funding hypothesis-driven basic research. The expectation is that proposed activities will generate practical tools, services, standardized methods, platforms, or other enabling infrastructure directly supporting preclinical therapeutic development in neurology.
What does "preclinical testing support" mean in this FOA?
In this announcement, preclinical testing support refers to products and services required to evaluate new neurological therapeutics before human trials. Examples mentioned or implied include assay development, validation platforms, specialized animal or cellular models, biomarkers, pharmacology/toxicology-related capabilities, data resources, and other shared translational infrastructure.
What funding mechanism is used?
The FOA uses the U24 Resource-Related Research Project Cooperative Agreement mechanism, which is a cooperative agreement rather than a standard research grant.
What does a U24 cooperative agreement imply for the relationship with NIH/NINDS?
A U24 cooperative agreement typically indicates a more hands-on partnership with NIH than a standard grant. Under this FOA, NINDS program staff are expected to have substantial involvement in the funded activities, reflecting a collaborative approach to ensuring the resource remains useful and aligned with translational needs.
What does "milestone-driven" mean for applicants?
Milestone-driven means applicants are expected to propose clear, measurable deliverables and timelines. Progress is likely to be tracked against predefined performance goals, emphasizing accountability and ensuring the funded resources remain reliable and useful for translational neurology.
What types of projects are a good fit for this program?
Projects that build, operate, and deliver specialized capabilities that enable preclinical testing for neurological therapeutics are the best fit. The FOA emphasizes shared, practical infrastructure and deliverable-focused work products rather than exploratory science.
Does the FOA specify the budget amount or number of awards?
No. The FOA leaves the funding size, project scope, and award duration intentionally flexible. NINDS did not specify a fixed number of awards or a standard budget level; the number of awards and total funding depend on application quality, the time required to complete the work, and the costs needed to carry out the resource center activities.
Is cost-sharing or matching required?
No cost-sharing or matching requirement is listed for this program.
Who is eligible to apply?
Eligibility is broad and includes many types of domestic organizations across nonprofit, academic, government, and private-sector categories. The eligibility listing includes nonprofits (with and without 501(c)(3) status), public and private institutions of higher education, small businesses, and for-profit organizations other than small businesses, as well as a wide range of government entities and tribal or indigenous-serving organizations.
Are for-profit organizations eligible?
Yes. The eligibility listing includes small businesses and for-profit organizations other than small businesses.
Are state, local, and tribal government entities eligible?
Yes. Eligible applicants include state governments, county governments, city or township governments, special district governments, independent school districts, certain housing authorities, federally recognized tribal governments, and tribal organizations that are not federally recognized, among others.
Are minority-serving institutions and community-based organizations included?
Yes. The eligibility listing explicitly includes organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, and tribally controlled colleges and universities.
Are U.S. territories or possessions eligible?
Yes. The eligibility listing includes U.S. territories or possessions.
Is this a discretionary grant and what category does it fall under?
Yes. This was a discretionary NIH grant opportunity categorized under health.
What CFDA number is associated with this opportunity?
The FOA is associated with CFDA 93.853, titled "Extramural Research Programs in the Neurosciences and Neurological Disorders."
When was this opportunity posted and when did it close?
The opportunity was posted on December 3, 2008. The original and final closing date was September 7, 2011.
Is this FOA still open for applications?
No. The opportunity was archived on October 8, 2011, following the final closing date.
Where was the full announcement hosted?
The full announcement was hosted through the NIH Grants Guide (linked in the notice).
Who provided support for access or linking issues?
NIH provided contact support through the NIH Office of Extramural Research web team for access or linking issues related to the announcement.
What is the overall intent of NINDS for this program?
The overall intent is to fund collaborative, deliverable-focused translational infrastructure in neurology that functions as shared resources, is managed under cooperative agreement terms with milestone accountability, and is funded with flexible budgets based on the scope and needs of the proposed resource center activities.
Browse more opportunities from the same category: Health
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