Opportunity Information: Apply for PAR 13 022

The NINDS Cooperative Program in Translational Research (U01) aims to advance the preclinical development and testing of new therapies for neurological disorders. This funding opportunity is designed to promote projects that transform basic research findings into potential clinical treatments. Applicants must present therapeutic leads and establish a strong biological rationale, including in vivo proof of concept where applicable.

Projects should be at a stage where submitting an Investigational New Drug (IND), Investigational Device Exemption (IDE), or a 510(k) application to the FDA is feasible during the grant period. This program also permits Phase 0 clinical trials for small molecule drugs and pilot studies for biologics or therapeutic devices. However, it does not cover early-stage discovery activities, general clinical research beyond specified phases, basic research, or studies focused on disease mechanisms.

The funding opportunity focuses solely on therapy development, meaning support for diagnostics, biomarkers, or rehabilitation strategies is excluded. This program operates as a milestone-driven cooperative agreement, which involves NINDS program staff in crafting the project plan and overseeing research progress.

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "NINDS Cooperative Program in Translational Research (U01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders.
  • This funding opportunity was created on Feb 13, 2014 and posted on Nov 19, 2012.
  • Applicants must submit their applications by Feb 13, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2025.)
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Public and State controlled institutions of higher education Private institutions of higher education Public housing authorities/Indian housing authorities Special district governments For profit organizations other than small businesses City or township governments Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) State governments County governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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