Opportunity Information: Apply for PAR 14 183

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "NINDS Program Project Grant (P01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders.
  • This funding opportunity was created on Apr 21, 2014 and posted on Apr 21, 2014.
  • Applicants must submit their applications by May 7, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Public housing authorities/Indian housing authorities City or township governments Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Small businesses Public and State controlled institutions of higher education Private institutions of higher education County governments Special district governments State governments Native American tribal organizations (other than Federally recognized tribal governments) Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Apply for PAR 14 183

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Opportunity Summary:

The NINDS Program Project Grant (P01) funding opportunity (PAR 14-183) is a National Institutes of Health (NIH) discretionary grant program created to support large, coordinated research efforts in the neurosciences and neurological disorders. It is designed for teams proposing innovative, interactive, and high-impact research that tackles significant scientific questions aligned with the mission of the National Institute of Neurological Disorders and Stroke (NINDS). The central idea behind this mechanism is that some scientific problems are better solved when multiple related projects are funded and managed together, rather than as separate, independent awards. In other words, applicants are expected to show that the proposed program is truly synergistic, meaning the collaborative structure itself creates clear scientific advantages, accelerates discovery, or enables approaches that would be difficult to achieve through individual stand-alone research grants.

A key emphasis of this opportunity is on interdependent, highly meritorious projects that function as parts of a single larger program. The FOA encourages applications built around strong scientific integration, where different projects inform each other, share resources or expertise, and collectively produce outcomes greater than what the same investigators could reasonably deliver if funded separately. The announcement also highlights the importance of collaboration among outstanding scientists, including partnerships that might not otherwise happen without a program structure that promotes deep coordination. In practical terms, a competitive application would be expected to articulate a compelling overarching theme, describe how the components connect scientifically, and demonstrate how cross-project interactions strengthen rigor, productivity, and impact.

From an administrative standpoint, this opportunity is a grant (FundingInstrumentType: Grant) within the Health funding activity category and is associated with CFDA number 93.853, which covers Extramural Research Programs in the Neurosciences and Neurological Disorders. The program does not require cost sharing or matching funds, which generally reduces barriers for institutions that may not have access to substantial non-federal resources. The opportunity was posted and created on April 21, 2014, with an original and current closing date of May 7, 2017, and an archive date of June 7, 2017, indicating that the specific announcement is no longer active for submission under that particular FOA number and date range.

Eligibility is broad and includes many types of organizations and governmental entities. Eligible applicants listed include public and state controlled institutions of higher education, private institutions of higher education, nonprofits (including both 501(c)(3) and certain non-501(c)(3) organizations outside higher education), for-profit organizations (including small businesses and other for-profits), and a wide range of government bodies such as state governments, county governments, city or township governments, special district governments, independent school districts, public housing authorities/Indian housing authorities, and tribal governments and tribal organizations (including federally recognized tribal governments and other tribal entities). The eligibility section further specifies additional eligible applicants such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal agencies. Importantly, the FOA states that foreign components, as defined in the NIH Grants Policy Statement, are allowed, which can enable international collaboration when it strengthens the science and fits NIH policy.

The sponsoring agency is the National Institutes of Health, and the complete announcement was made available through the NIH Grants Guide. The FOA link provided in the source is: http://grants.nih.gov/grants/guide/pa-files/PAR-14-183.html. For technical issues accessing or linking to the announcement, the contact provided is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV. Overall, this opportunity is best understood as a mechanism for ambitious, collaborative neuroscience programs where multiple connected projects are intentionally structured to work together, with integration and collective impact serving as the main justification for using the P01 program project format.

FAQs: NINDS Program Project Grant (P01) - PAR-14-183

What is the NINDS Program Project Grant (P01) opportunity (PAR-14-183)?

PAR-14-183 is a National Institutes of Health (NIH) discretionary grant funding opportunity from the National Institute of Neurological Disorders and Stroke (NINDS). It supports large, coordinated research efforts in the neurosciences and neurological disorders using the Program Project Grant (P01) mechanism.

What is the main purpose of the P01 mechanism in this announcement?

The purpose is to fund multiple related projects as one integrated program when a scientific problem is better solved through a coordinated, collaborative structure rather than through separate, independent awards.

What kinds of research programs are a strong fit for this FOA?

This FOA is designed for innovative, interactive, high-impact research programs that tackle significant scientific questions aligned with the mission of NINDS, and where the overall program depends on interdependent projects working together.

What does "synergistic" mean in the context of this P01 opportunity?

Synergistic means the combined, coordinated program creates clear scientific advantages over stand-alone projects. The application is expected to show that collaboration accelerates discovery, enables approaches that would be difficult otherwise, or produces outcomes greater than what the same investigators could reasonably deliver if funded separately.

What does the FOA emphasize about project structure?

The FOA emphasizes interdependent, highly meritorious projects that function as parts of a single larger program, with strong scientific integration and meaningful cross-project interaction.

What is meant by "scientific integration" in this announcement?

Scientific integration refers to how the different projects connect and inform each other, share resources or expertise, and collectively strengthen rigor, productivity, and impact under a unifying program theme.

What are applicants expected to explain about cross-project collaboration?

Applicants are expected to articulate a compelling overarching theme, describe how components connect scientifically, and demonstrate how cross-project interactions strengthen the overall program and create added value beyond independent grants.

Who is the sponsoring agency for this opportunity?

The sponsoring agency is the National Institutes of Health (NIH), specifically through the National Institute of Neurological Disorders and Stroke (NINDS).

What type of funding instrument is PAR-14-183?

It is a grant (FundingInstrumentType: Grant).

What is the funding activity category associated with this opportunity?

The funding activity category is Health.

What is the CFDA number associated with this program?

The CFDA number is 93.853, associated with Extramural Research Programs in the Neurosciences and Neurological Disorders.

Is cost sharing or matching required?

No. The opportunity states that cost sharing or matching funds are not required.

When was this opportunity posted and created?

It was posted and created on April 21, 2014.

What were the closing date and archive date listed for this FOA?

The original and current closing date listed is May 7, 2017, and the archive date is June 7, 2017.

Is this specific FOA currently active for submission?

Based on the listed closing and archive dates, this particular announcement (PAR-14-183, with that date range) is no longer active for submission.

Where can the full FOA be found?

The FOA is available through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PAR-14-183.html.

What types of organizations are eligible to apply?

Eligibility is broad and includes public and state controlled institutions of higher education, private institutions of higher education, nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) organizations outside higher education), and for-profit organizations (including small businesses and other for-profits).

Are government entities eligible to apply?

Yes. Eligible applicants include state governments, county governments, city or township governments, special district governments, independent school districts, public housing authorities/Indian housing authorities, and tribal governments and tribal organizations (including federally recognized tribal governments and other tribal entities).

Are minority-serving institutions included in the eligibility list?

Yes. The eligibility section specifically includes Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs).

Are faith-based or community-based organizations eligible?

Yes. The eligibility section includes faith-based or community-based organizations.

Are U.S. territories or possessions included as eligible applicants?

Yes. The eligibility section includes U.S. territories or possessions.

Are federal agencies eligible to apply?

Yes. The eligibility list includes eligible federal agencies.

Are foreign components allowed?

Yes. The FOA states that foreign components (as defined in the NIH Grants Policy Statement) are allowed, enabling international collaboration when it strengthens the science and fits NIH policy.

What is the overall takeaway for applicants considering a P01 under this FOA?

This opportunity is intended for ambitious, collaborative neuroscience programs with multiple connected projects intentionally structured to work together, where integration and collective impact are the main justification for using the P01 program project format.

Who should be contacted for technical issues accessing or linking to the announcement?

For technical issues accessing or linking to the announcement, the contact provided is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

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