Opportunity Information: Apply for PAR 10 091

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "NINDS Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellows in MD PhD programs (F31)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders.
  • This funding opportunity was created on Nov 5, 2010 and posted on Jan 22, 2010.
  • Applicants must submit their applications by Jan 7, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Public and State controlled institutions of higher education For profit organizations other than small businesses Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) .
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Opportunity Summary:

PAR-10-091 is a National Institutes of Health (NIH) discretionary grant opportunity from the National Institute of Neurological Disorders and Stroke (NINDS) that supports individual predoctoral fellows through the Ruth L. Kirschstein National Research Service Award (NRSA) F31 mechanism. The program is specifically aimed at promising trainees who are enrolled in combined MD-PhD programs and are moving into (or are already engaged in) their dissertation research phase. In practical terms, it is designed to help physician-scientist trainees build deep research skills and a strong scientific foundation while completing a PhD dissertation in areas that align with NINDS priorities, meaning neuroscience, neurological disorders, stroke, and closely related biomedical or behavioral research areas that fit within the institute's mission.

The central purpose of the fellowship is training-oriented: it is meant to invest in the development of the applicant as an independent researcher, not simply to bankroll a project. Successful applications generally need to make a compelling case that the candidate is on a trajectory to become a productive physician-scientist, that the proposed dissertation research is scientifically meritorious and feasible, and that the training plan and mentorship environment will meaningfully advance the fellow's skills. Because it is an individual fellowship, the applicant (the MD-PhD trainee) is the focal point, with strong emphasis placed on the quality of the mentorship, the research setting, and how the planned research and training experiences will prepare the trainee for a research career relevant to neurological health and disease.

This FOA uses the NIH NRSA Individual Predoctoral Fellowship (F31) mechanism, which is the standard NIH framework for supporting predoctoral trainees through stipends and training-related expenses under the NRSA authority. The announcement notes that the amount of funding and the number of awards are not fixed in advance. Instead, award levels depend on three main factors: the overall quality and scientific merit of the applications received, how well the proposed work aligns with NINDS program priorities, and the availability of funds in a given cycle. This means the competition is primarily merit-driven, and mission relevance to NINDS is a key consideration alongside peer review scoring.

From an eligibility standpoint, the opportunity is broadly open on the institutional side to a wide range of organizations that can sponsor the fellowship, including public and state-controlled institutions of higher education, private institutions of higher education, and certain nonprofit and for-profit organizations (with details subject to the FOA text). The listing also highlights inclusivity of institutions serving specific populations, including Alaska Native and Native Hawaiian Serving Institutions, Hispanic-Serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and eligible federal agencies. Importantly, while institutions submit and administer the award, the fellowship is intended for individual MD-PhD predoctoral candidates, consistent with the F31 purpose.

Administrative details in the source information place the FOA within the NIH Grants Guide timeframe. It was posted January 22, 2010, with key dates indicating that the opportunity was active during that period and later archived (archive date listed as February 7, 2011). The CFDA number associated with this program is 93.853, categorized under extramural research programs in the neurosciences and neurological disorders. The announcement also explicitly states there is no cost sharing or matching requirement, which is typical for NIH fellowships and reduces institutional financial burden as a condition of applying.

For applicants or institutions needing the full official announcement and requirements, the FOA is linked through the NIH Grants Guide at http://grants.nih.gov/grants/guide/pa-files/PAR-10-091.html. The provided contact pathway for access or technical linking problems is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV, which is meant to help users who cannot retrieve the full posting or encounter issues accessing it online.

Frequently Asked Questions (FAQs) - PAR-10-091 (NIH/NINDS NRSA F31 for MD-PhD Predoctoral Fellows)

What is PAR-10-091?

PAR-10-091 is a National Institutes of Health (NIH) discretionary grant opportunity from the National Institute of Neurological Disorders and Stroke (NINDS). It supports individual predoctoral fellows through the Ruth L. Kirschstein National Research Service Award (NRSA) F31 mechanism.

What type of award mechanism does this program use?

This opportunity uses the NIH NRSA Individual Predoctoral Fellowship (F31) mechanism, which is NIH's standard framework for supporting individual predoctoral trainees through stipends and training-related expenses under NRSA authority.

Who is this fellowship designed for?

The program is specifically aimed at promising trainees who are enrolled in combined MD-PhD programs and are moving into (or are already engaged in) their dissertation research phase.

Is this funding focused on the trainee or the research project?

The central purpose is training-oriented. It is meant to invest in the development of the applicant as an independent researcher, not simply to bankroll a project. The application is expected to make a strong case for the candidate's potential, training plan, mentorship, and research environment, alongside the merit and feasibility of the proposed dissertation research.

What research areas are considered a good fit for PAR-10-091?

The proposed dissertation research should align with NINDS priorities, including neuroscience, neurological disorders, stroke, and closely related biomedical or behavioral research areas that fit within the NINDS mission.

What does NINDS emphasize when deciding what to fund?

Based on the information provided, NINDS considers: (1) overall quality and scientific merit of applications, (2) alignment with NINDS program priorities, and (3) availability of funds in a given cycle. This makes the competition primarily merit-driven, with mission relevance being a key factor alongside peer review.

Are the number of awards and funding amounts predetermined?

No. The announcement notes that the amount of funding and the number of awards are not fixed in advance. Award levels depend on application quality and scientific merit, alignment with NINDS priorities, and funds available.

Who is the applicant for an individual F31 fellowship under this FOA?

Because this is an individual fellowship, the MD-PhD trainee is the focal point of the application. The training plan, mentorship, research setting, and how the experiences will prepare the trainee for a research career relevant to neurological health and disease are central.

What role does the sponsoring institution play?

Institutions submit and administer the award, but the fellowship is intended for individual MD-PhD predoctoral candidates consistent with the NRSA F31 purpose.

What types of organizations are eligible to sponsor the fellowship?

The opportunity is broadly open on the institutional side to a range of organizations that can sponsor the fellowship, including public and state-controlled institutions of higher education, private institutions of higher education, and certain nonprofit and for-profit organizations (with details subject to the FOA text).

Are minority-serving institutions included as eligible organizations?

Yes. The listing highlights inclusivity of institutions serving specific populations, including Alaska Native and Native Hawaiian Serving Institutions, Hispanic-Serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), and eligible federal agencies.

Is cost sharing or matching required?

No. The announcement explicitly states there is no cost sharing or matching requirement.

What is the CFDA number for this program?

The CFDA number associated with this program is 93.853, categorized under extramural research programs in the neurosciences and neurological disorders.

When was PAR-10-091 posted, and what is its archive status?

Administrative details indicate the FOA was posted on January 22, 2010. It was later archived, with an archive date listed as February 7, 2011.

Where can someone find the official FOA text?

The full announcement and official requirements are available through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PAR-10-091.html

Who should be contacted if there are technical problems accessing the FOA online?

If someone cannot retrieve the full posting or encounters access issues, the provided contact pathway is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.

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