NINDS SBIR Technology Transfer (SBIR TT R43/R44) | Apply Online

Opportunity Summary:

The NINDS SBIR Technology Transfer (SBIR TT R43/R44) opportunity, listed under Funding Opportunity Number PA 11-347, is a National Institutes of Health (NIH) grant program designed to help small businesses move promising inventions from NIH intramural laboratories into the private sector. The central goal is technology transfer: taking government-developed biomedical and health-related innovations that already exist within NIH labs and enabling a Small Business Concern (SBC) to further develop them into real-world commercial products that ultimately benefit patients and the public. In other words, this announcement is aimed at bridging the gap between discovery inside NIH and product development in industry by giving qualified small businesses funding support and a pathway to use NIH-owned technologies.

This is an SBIR grant mechanism, meaning it supports early-stage research and development carried out by eligible small businesses, typically through the SBIR phased structure associated with R43/R44 awards. While the source text does not lay out the full phase details, the R43/R44 format generally aligns with feasibility work and early proof-of-concept efforts followed by more advanced development steps. The distinctive feature here is that the supported project is explicitly tied to transferring an NIH intramural technology out into the marketplace, rather than starting from scratch with a company-owned invention. The program encourages companies to identify an NIH-held technology that fits a commercial need, propose a development plan, and use SBIR funding to advance it toward a product.

A key incentive included in the program is licensing access to NIH technologies. If an SBC is selected for SBIR funding under this FOA, it will be granted a royalty-free, non-exclusive internal research use license for the duration of the SBIR award and within the specific field of use tied to the award. This licensing arrangement is meant to lower barriers for companies that want to evaluate, validate, and develop NIH-owned inventions during the funded period. The expectation is that the small business will take concrete steps to mature the invention into a commercial product, positioning it for later-stage investment, regulatory planning where applicable, manufacturing scale-up, partnerships, or additional funding that leads to public impact.

Administratively, this opportunity is categorized as discretionary funding and uses the grant funding instrument. The sponsoring agency is the National Institutes of Health. The activity category is health, and the program is connected to multiple CFDA numbers spanning sleep disorders research (93.233), cardiovascular diseases (93.837), lung diseases (93.838), blood diseases and resources (93.839), neurosciences and neurological disorders research programs (93.853), and vision research (93.867). Even though the title highlights NINDS and technology transfer, these CFDA references suggest the underlying research and potential technologies may span a broad biomedical scope, including neurology-focused innovations as well as related areas that overlap with neurological function or comorbid conditions.

Eligibility is limited to small businesses, consistent with SBIR rules, and there is no cost sharing or matching requirement, which can be important for early-stage companies that need non-dilutive capital without having to provide matching funds. The listed award ceiling in the provided data is $150,000, which can be interpreted as a cap for at least one stage or component as presented in the summary data (SBIR awards often have phase-based budgets and specific NIH policy caps, but the number here is what is explicitly provided in the source).

Timing details in the record indicate the FOA was posted on September 22, 2011, with later record creation dated July 18, 2014. The original closing date is shown as September 7, 2014, and the current closing date is shown as July 19, 2014, with an archive date of August 19, 2014. Practically, this means the announcement is historical/archived rather than currently open, but the structure and intent are still useful as a model for similar NIH technology transfer-focused SBIR efforts.

For further information, the announcement points to the NIH Grants Guide page (http://grants.nih.gov/grants/guide/pa-files/PA-11-347.html). For access or technical issues, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV, specifically for difficulties accessing or linking to the announcement electronically.

Overall, this FOA is best understood as a targeted commercialization pipeline tool: it encourages small businesses to take NIH intramural inventions, secure a limited research-use license during the grant term, and apply SBIR-funded R&D to transform those inventions into products that can be deployed outside government labs for public benefit.

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