Opportunity Information: Apply for RFA RM 14 013
Apply for RFA RM 14 013
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Novel and Innovative Tools to Facilitate Identification, Tracking, Manipulation, and Analysis of Glycans and their Functions (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310 Trans NIH Research Support.
- This funding opportunity was created on Sep 30, 2014 and posted on Sep 30, 2014.
- Applicants must submit their applications by Dec 10, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments State governments Small businesses Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education Independent school districts Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) City or township governments For profit organizations other than small businesses.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Opportunity Summary:
The NIH Common Fund funding opportunity titled "Novel and Innovative Tools to Facilitate Identification, Tracking, Manipulation, and Analysis of Glycans and their Functions (U01)" is focused on removing longstanding practical barriers that have made glycans (complex carbohydrates) difficult to study in everyday biomedical research. Through the Common Fund program "Accelerating Translation of Glycoscience Integration and Accessibility," NIH is aiming to push glycoscience beyond a specialized niche by supporting the creation of tools and technologies that are easier to use, more widely available, and more affordable. The driving idea behind the program is that many researchers avoid or abandon glycan-related questions because current methods can be technically demanding, expensive, or hard to integrate into standard laboratory workflows, even though glycans play major roles in health and disease.
This announcement specifically solicits projects that develop new or significantly improved tools, reagents, and technologies that make it easier to identify glycans, track them in biological systems, manipulate them experimentally, and analyze their interactions with biological binding partners in order to determine function. In practice, that can include approaches that help researchers detect specific glycan structures, follow glycan changes across cell states or disease progression, perturb glycan synthesis or presentation to test causality, or map glycan-protein (and other glycan-partner) interactions that explain biological effects. The FOA also makes room for efforts that build on existing technologies, but with a clear emphasis on making those technologies more accessible to the broader community. In other words, it is not just about creating something cutting-edge in a specialized setting; it is about lowering the friction that prevents non-experts from applying glycoscience tools in routine biomedical studies.
A major practical requirement embedded in the opportunity is attention to real-world usability and downstream adoption. Applicants are expected, where applicable, to consider scale-up needs so that resulting instrumentation or platforms can be broadly accessible and cost-effective for end users, rather than remaining custom, boutique prototypes. Another important emphasis is data compatibility: projects should consider whether the data produced can be integrated into existing databases, which signals a strong interest in standardization, interoperability, and community-wide reuse of datasets rather than isolated, one-off outputs. Taken together, these expectations point to NIH wanting deliverables that can spread across laboratories and disciplines, support reproducible science, and plug into the broader biomedical data ecosystem.
Mechanistically, this is a discretionary cooperative agreement using the U01 activity code, meaning NIH anticipates substantial programmatic involvement compared with a standard investigator-initiated grant. The total estimated funding for the opportunity is $1,000,000, with an award ceiling of $500,000, and NIH expected to make about two awards. There is no cost sharing or matching requirement. The opportunity was posted on September 30, 2014, with an original and final application due date of December 10, 2014, and an archive date of January 10, 2015.
Eligibility is broad across sectors, reflecting the translational and tool-building nature of the program. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status), small businesses, and for-profit organizations other than small businesses, as well as a range of government entities such as state governments, county governments, city or township governments, special district governments, and certain housing authorities. The eligibility list also explicitly includes various mission-driven and capacity-building institution types and organizations, including historically Black colleges and universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian serving institutions, and Asian American, Native American, and Pacific Islander serving institutions (AANAPISIs), along with faith-based or community-based organizations and eligible federal agencies. While foreign components are allowed as defined by NIH policy, non-U.S. entities and non-U.S. components of U.S. organizations are not eligible to apply, which keeps primary award responsibility within U.S.-based institutions.
Overall, the grant opportunity is designed to accelerate practical, widely adoptable glycoscience capabilities by funding projects that deliver user-friendly ways to detect, interrogate, and manipulate glycans and their interactions, while also planning for scale, affordability, and data integration. The intended outcome is a toolbox that lets a much larger fraction of biomedical researchers incorporate glycan biology into mainstream studies of mechanisms, biomarkers, and therapeutic targets, rather than treating glycans as too complex or inaccessible to pursue.
Frequently Asked Questions (FAQs)
What is the title of this NIH funding opportunity?
The funding opportunity is titled "Novel and Innovative Tools to Facilitate Identification, Tracking, Manipulation, and Analysis of Glycans and their Functions (U01)."
Which NIH program is sponsoring this opportunity?
This opportunity is offered through the NIH Common Fund program "Accelerating Translation of Glycoscience Integration and Accessibility."
What is the overall purpose of this funding opportunity?
The goal is to remove practical barriers that have historically made glycans (complex carbohydrates) difficult to study in everyday biomedical research. NIH is seeking tools and technologies that are easier to use, more widely available, and more affordable so glycoscience can be used beyond a specialized niche.
Why is NIH emphasizing glycan-focused tool development?
The opportunity is driven by the idea that many researchers avoid or abandon glycan-related questions because current methods can be technically demanding, expensive, or hard to integrate into standard lab workflows, even though glycans play major roles in health and disease.
What types of projects does this FOA solicit?
The FOA solicits projects that develop new or significantly improved tools, reagents, and technologies that make it easier to identify glycans, track them in biological systems, manipulate them experimentally, and analyze their interactions with biological binding partners to determine function.
What kinds of glycan capabilities are specifically in scope?
In-scope capabilities include approaches that help researchers:
- Detect or identify specific glycan structures
- Track glycan changes across cell states or disease progression
- Perturb glycan synthesis or presentation to test causality
- Map interactions between glycans and biological binding partners (such as glycan-protein interactions) to explain biological effects
Does the FOA allow improvements to existing technologies, or only completely new tools?
The FOA makes room for efforts that build on existing technologies, but it emphasizes making those technologies more accessible to the broader community. The intent is not only cutting-edge performance in a specialized setting, but reduced friction for non-experts using glycoscience tools in routine biomedical studies.
How important is usability for non-expert labs?
Usability and downstream adoption are central expectations. The opportunity explicitly aims to lower barriers that keep non-experts from applying glycoscience tools in standard laboratory workflows.
Are applicants expected to plan for scale-up and broad access?
Yes. Where applicable, applicants are expected to consider scale-up needs so resulting instrumentation or platforms can be broadly accessible and cost-effective for end users, rather than remaining custom or boutique prototypes.
What does the FOA say about data standards and database compatibility?
Projects should consider whether the data produced can be integrated into existing databases. This signals an emphasis on standardization, interoperability, and community-wide reuse of datasets rather than isolated, one-off outputs.
What funding mechanism is used for this opportunity?
This is a discretionary cooperative agreement using the U01 activity code.
What does a U01 cooperative agreement imply about NIH involvement?
A U01 indicates NIH anticipates substantial programmatic involvement compared with a standard investigator-initiated grant.
How much total funding is estimated for this opportunity?
The total estimated funding is $1,000,000.
What is the maximum award amount (award ceiling)?
The award ceiling is $500,000.
How many awards does NIH expect to make?
NIH expects to make about two awards.
Is cost sharing or matching required?
No. There is no cost sharing or matching requirement.
When was the opportunity posted?
The opportunity was posted on September 30, 2014.
What were the application due dates?
The original and final application due date was December 10, 2014.
When was the archive date for the opportunity?
The archive date was January 10, 2015.
Who is eligible to apply?
Eligibility is broad across sectors. Eligible applicants include:
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Nonprofit organizations (with or without 501(c)(3) status)
- Small businesses
- For-profit organizations other than small businesses
- State governments
- County governments
- City or township governments
- Special district governments
- Certain housing authorities
- Faith-based or community-based organizations
- Eligible federal agencies
Are mission-driven and capacity-building institutions explicitly included in eligibility?
Yes. The eligibility list explicitly includes institution types and organizations such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian serving institutions, and Asian American, Native American, and Pacific Islander serving institutions (AANAPISIs).
Are foreign components allowed?
Yes. Foreign components are allowed as defined by NIH policy.
Are non-U.S. entities eligible to apply?
No. Non-U.S. entities and non-U.S. components of U.S. organizations are not eligible to apply, which keeps primary award responsibility within U.S.-based institutions.
What outcomes is NIH ultimately trying to achieve with this program?
The intended outcome is a toolbox of practical, widely adoptable glycoscience capabilities that lets a much larger fraction of biomedical researchers incorporate glycan biology into mainstream studies of mechanisms, biomarkers, and therapeutic targets, rather than treating glycans as too complex or inaccessible to pursue.
Is the FOA mainly about creating specialized, high-end prototypes?
No. While innovative technologies are encouraged, the FOA emphasizes real-world usability, affordability, and broad adoption. It specifically points toward deliverables that can spread across laboratories and disciplines rather than remaining custom, boutique prototypes.
How does this FOA connect tool development to biological function?
The FOA focuses on tools that help determine glycan function by enabling identification, tracking in biological systems, experimental manipulation to test causality, and analysis of interactions with biological binding partners.
Browse more opportunities from the same category: Health
Next opportunity: Official U.S. Presentation at the 15th International Architecture Exhibition, Venice, Italy, June Through November, 2016
Previous opportunity: Novel and Innovative Tools to Facilitate Identification, Tracking, Manipulation, and Analysis of Glycans and their Functions (R21)
USGrants.org Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for RFA RM 14 013
[Watch] how do funding administrators access proposals?
Applicants also applied for:
Applicants who have applied for this opportunity (RFA RM 14 013) also looked into and applied for these:
| Funding Opportunity |
|---|
| Data Integration and Analysis Tools Accessible Resources for Integration and Analysis of Carbohydrate and Glycoconjugate Structural, Analytical, and Interaction Data in the Context of Comparable Gene, Protein, and Lipid Data (R34) Apply for RFA RM 14 012 Funding Number: RFA RM 14 012 Agency: National Institutes of Health Category: Health Funding Amount: $150,000 |
| Strengthen Capacity of the Ministry of Community Development, Mother and Child Health to Support National Coordination of HIV Prevention, Care and Treatment and Related Maternal, Neonatal and Child Health Serv at District FacilityCommunity Level (PEP Apply for CDC RFA GH15 1599 Funding Number: CDC RFA GH15 1599 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $1,975,000 |
| Strengthening the Healthcare System of Vietnam through Capacity Building, Policy Development and Quality Improvement of Laboratory and Clinical Services under the Presidents Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH15 1596 Funding Number: CDC RFA GH15 1596 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $500,000 |
| Strengthening Human Resources for Health Capacity in the Republic of Rwanda under the Presidents Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH15 1568 Funding Number: CDC RFA GH15 1568 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $14,000,000 |
| Provision of Comprehensive HIV/AIDS, STI and TB Services Including Prevention, Care, Support and Treatment to Prisoners and Staff of the Prisons Service in the Republic of Uganda under the Presidents Emergency Plan for AIDS Relief Apply for CDC RFA GH15 1590 Funding Number: CDC RFA GH15 1590 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $1,200,000 |
| Support the Mandate of the Ministry of Health and Social Welfare in the United Republic of Tanzania to Centrally Coordinate National Blood Transfusion Services in order to Ensure an Adequate and Safe Blood Supply under PEPFAR Apply for CDC RFA GH15 1588 Funding Number: CDC RFA GH15 1588 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $5,000,000 |
| Implementing Technical and Science Support Services (TSSS) in the Republic of Rwanda under PEPFAR Apply for CDC RFA GH15 1570 Funding Number: CDC RFA GH15 1570 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $12,078,648 |
| Pre Symptomatic Profiles of Chronic Lung Disease(s) from Retrospective Cohorts (R21) Apply for RFA HL 15 025 Funding Number: RFA HL 15 025 Agency: National Institutes of Health Category: Health Funding Amount: $275,000 |
| The Midlife in the United States Study (U19) Apply for PAR 14 356 Funding Number: PAR 14 356 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Strengthening the Capacity of the Republican Blood Center to Scale Up Blood Safety Program in the Kyrgyzstan Republic under the Presidents Emergency Plan for AIDS Relief (PEPFAR) Apply for CC RFA GH15 1512 Funding Number: CC RFA GH15 1512 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $100,000 |
| Strengthening the Capacity of the Republican Blood Center to Scale Up Blood Safety Program in Tajikistan (TJ) under the President Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH15 1513 Funding Number: CDC RFA GH15 1513 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $100,000 |
| Strengthening HIV Clinical Services in the Republic of Rwanda under the Presidents Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH15 1567 Funding Number: CDC RFA GH15 1567 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $30,000,000 |
| Building Sustainable Capacity of the Ministry of Home Affairs to Address HIV and TB Prevention, Care and Treatment in Zambian Prisons and Respond to Child Sexual Abuse and Sexual Gender Based Violence in the Republic of Zambia under the Presidents Em Apply for CDC RFA GH15 1601 Funding Number: CDC RFA GH15 1601 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $2,500,000 |
| Definition of Resilience and Pre Symptomatic Disease in Lung Health and Disease (R01) Apply for RFA HL 15 024 Funding Number: RFA HL 15 024 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Technical Assistance to Support the Implementation and Evaluation of HIV/AIDS Prevention, Care, Treatment, and Support Activities for Mothers, Children, and Families under the Presidents Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH15 1531 Funding Number: CDC RFA GH15 1531 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $6,000,000 |
| Strengthening Blood Transfusion Services in the Republic of Mozambique under the Presidents Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH15 1559 Funding Number: CDC RFA GH15 1559 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $1,000,000 |
| Regional Consortia for High Resolution Cryoelectron Microscopy (U24) Apply for RFA GM 16 001 Funding Number: RFA GM 16 001 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Ensuring Reliable and Equitable Access to PMTCT Services for Key Populations in the Republic of Mali under the Presidents Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH15 1605 Funding Number: CDC RFA GH15 1605 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $250,000 |
| Biology of the Temporomandibular Joint in Health and Disease (R01) Apply for PA 14 358 Funding Number: PA 14 358 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Strengthen the Capacity of the Republic of Malis National Institute for Public Health Research (INRSP) to Implement Laboratory Based Activities and Research in Support of STI/HIV Prevention and Care Services under the Presidents Emergency Plan for AI Apply for CDC RFA GH15 1606 Funding Number: CDC RFA GH15 1606 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $250,000 |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Subscribe to Leads
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "RFA RM 14 013", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.