Opportunity Information: Apply for PAR 16 015

  • The HHS-NIH11 in the health sector is offering a public funding opportunity titled "Novel Genomic Technology Development (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172,.
  • This funding opportunity was created on Oct 27, 2015 and posted on Oct 27, 2015.
  • Applicants must submit their applications by Jan 11, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
Apply for PAR 16 015

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Opportunity Summary:

The Novel Genomic Technology Development (R21) opportunity (Funding Opportunity Number PAR 16-015) is a discretionary NIH grant program intended to spark major, forward-looking advances in genomics by funding early-stage technology development. It sits in the health research funding category (CFDA 93.172) and is administered under HHS/NIH (listed as HHS-NIH11). The core purpose is to create a supportive pathway for highly innovative, potentially high-impact ideas that could reshape how genomic research is done, with the expectation that the resulting tools or methods could meaningfully influence the field within roughly the next five to seven years.

A key point is what this FOA is and is not targeting. It is specifically aimed at genomics technology development beyond simply inventing new nucleic acid sequencing technologies. In other words, while sequencing is a foundational area in genomics, this announcement is looking to catalyze breakthroughs across the broader technology landscape that enables genomic discovery and application. The emphasis is on novelty and impact, supporting concepts that may be at an earlier or riskier stage than typical incremental improvements, but that could open up new capabilities for generating, measuring, interpreting, or using genomic information.

The funding mechanism is an R21, which generally aligns with exploratory or developmental work where the goal is to establish feasibility, develop a proof of concept, or demonstrate a new technical approach that can later scale into larger studies or platforms. The listed award ceiling is $200,000, signaling support for compact, targeted projects designed to move a bold technical idea from concept toward a credible prototype or validated method. While the number of expected awards is not specified in the provided data, the intent is clearly to seed multiple novel approaches rather than fund a single large effort.

Eligibility is broad and includes many types of organizations that participate in biomedical and technology research. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations other than federally recognized tribal governments; public housing authorities/Indian housing authorities; nonprofits with or without 501(c)(3) status (excluding higher education institutions in those nonprofit categories); for-profit organizations other than small businesses; small businesses; and other entities as allowed under the announcement’s additional eligibility language. This wide eligibility suggests the program is meant to draw strong technology concepts from universities, research institutes, government-affiliated entities, and the private sector, including smaller and larger commercial organizations where appropriate.

Administratively, the FOA was created and posted on October 27, 2015, and the closing date in the provided record is January 11, 2018 (both original and current closing dates are the same). Overall, this opportunity is best understood as NIH’s attempt to accelerate the next wave of genomics-enabling technologies by giving investigators room to pursue unconventional, high-upside technical ideas that could materially expand what is possible in genomics over the medium term.

Frequently Asked Questions (FAQs)

What is the Novel Genomic Technology Development (R21) opportunity?

The Novel Genomic Technology Development (R21) opportunity is an NIH discretionary grant program designed to stimulate major, forward-looking advances in genomics by supporting early-stage technology development. It is associated with Funding Opportunity Number (FOA) PAR 16-015.

Which agency administers this grant program?

This funding opportunity is administered under HHS/NIH (listed as HHS-NIH11).

What is the main purpose of this FOA?

The core purpose is to create a supportive pathway for highly innovative, potentially high-impact genomics technology ideas that could reshape how genomic research is done, with the expectation that resulting tools or methods could meaningfully influence the field within roughly the next five to seven years.

What kind of projects is this FOA trying to support?

This FOA emphasizes novelty and impact in genomics technology development. It is meant to support bold concepts, including ideas that may be earlier-stage or riskier than typical incremental improvements, as long as they could open new capabilities for generating, measuring, interpreting, or using genomic information.

Is this funding opportunity focused on inventing new DNA/RNA sequencing technologies?

No. A key point is that this FOA is aimed at genomics technology development beyond simply inventing new nucleic acid sequencing technologies. While sequencing is foundational to genomics, this announcement is intended to catalyze breakthroughs across the broader technology landscape that enables genomic discovery and application.

What does the R21 funding mechanism imply about the stage of work expected?

The R21 mechanism generally aligns with exploratory or developmental work. It is commonly used to establish feasibility, develop a proof of concept, or demonstrate a new technical approach that could later scale into larger studies or platforms.

What is the award ceiling for this opportunity?

The listed award ceiling is $200,000, indicating support for compact, targeted projects intended to move a bold technical idea from concept toward a credible prototype or validated method.

How many awards will NIH make under this FOA?

The number of expected awards is not specified in the provided information. The stated intent is to seed multiple novel approaches rather than fund a single large effort.

What funding category is this opportunity associated with?

This opportunity sits in the health research funding category and is associated with CFDA 93.172.

Who is eligible to apply?

Eligibility is broad. Eligible applicants include:

  • State governments
  • County governments
  • City or township governments
  • Special district governments
  • Independent school districts
  • Public and state-controlled institutions of higher education
  • Private institutions of higher education
  • Federally recognized Native American tribal governments
  • Native American tribal organizations other than federally recognized tribal governments
  • Public housing authorities / Indian housing authorities
  • Nonprofits with 501(c)(3) status (excluding higher education institutions in those nonprofit categories)
  • Nonprofits without 501(c)(3) status (excluding higher education institutions in those nonprofit categories)
  • For-profit organizations other than small businesses
  • Small businesses
  • Other entities as allowed under the announcement’s additional eligibility language

Does the FOA allow applications from the private sector?

Yes. The eligible applicant list includes for-profit organizations (other than small businesses) as well as small businesses, indicating the program is intended to draw strong technology concepts from both academic and commercial organizations.

Are government-affiliated entities eligible?

Yes. The eligible applicant types include several levels of government (state, county, city/township), special district governments, and independent school districts, as well as public housing authorities/Indian housing authorities.

Are tribal governments and tribal organizations eligible?

Yes. Federally recognized Native American tribal governments are eligible, and Native American tribal organizations other than federally recognized tribal governments are also listed as eligible.

What is the FOA number for this opportunity?

The Funding Opportunity Number is PAR 16-015.

When was this FOA posted?

The FOA was created and posted on October 27, 2015.

What is the closing date for this opportunity (based on the provided record)?

The closing date listed in the provided record is January 11, 2018. The record indicates the original and current closing dates are the same.

What is the overall goal NIH is trying to achieve with this program?

Overall, the program is intended to accelerate the next wave of genomics-enabling technologies by giving investigators room to pursue unconventional, high-upside technical ideas that could materially expand what is possible in genomics over the medium term.

What timeline of potential impact does NIH expect from supported technologies?

The expectation described is that the resulting tools or methods could meaningfully influence the field within roughly the next five to seven years.

Is this FOA intended for large, multi-year, expansive efforts?

Based on the R21 mechanism and the $200,000 award ceiling, the opportunity is described as supporting compact, targeted projects focused on feasibility, proof of concept, prototype development, or method validation rather than a single large, expansive effort.

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