Opportunity Information: Apply for RFA DK 13 026
Apply for RFA DK 13 026
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Novel Methods for Detection and Measurement of Organ Fibrosis in Kidney, Bone Marrow and Urological Diseases (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on Oct 22, 2013 and posted on Oct 22, 2013.
- Applicants must submit their applications by Mar 19, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,500,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $250,000.00 in funding.
- The number of recipients for this funding is limited to 4 candidate(s).
- Eligible applicants include: For profit organizations other than small businesses Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Small businesses City or township governments Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education County governments Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
This funding opportunity, RFA-DK-13-026, is an NIH discretionary grant solicitation that uses the U01 cooperative agreement mechanism to build a research consortium focused on new ways to detect and measure organ fibrosis. The scientific aim centers on fibrosis that develops after acute or chronic injury, specifically in the kidney, bone marrow, prostate, and broader urological or urinary tract contexts. The core idea is that fibrosis is a common and often decisive driver of long-term organ dysfunction across these systems, yet it can be difficult to quantify accurately, track over time, or compare across studies and clinical settings. By emphasizing "novel methods" for detection and measurement, the FOA signals interest in tools, technologies, biomarkers, imaging approaches, and analytical frameworks that can improve how fibrosis is identified, staged, monitored, and potentially used as an endpoint for research and therapeutic development.
The award type is a cooperative agreement (U01), which typically means NIH expects substantial scientific and/or programmatic involvement during the project period. In practical terms, this structure fits a consortium model where multiple awardees coordinate on shared goals, harmonize methods, and contribute to common resources or standards, rather than operating as fully independent projects. The FOA explicitly states its purpose is to establish a consortium, so applicants would generally be expected to describe how they will collaborate, share data or protocols, and contribute to consortium-wide milestones that accelerate progress beyond what a single laboratory could accomplish alone.
Financially, the FOA anticipated making about 4 awards, with an estimated total funding level of $1,500,000. The listed award ceiling is $250,000, which indicates a maximum funding amount per award under the terms described in the source summary. There is no cost sharing or matching requirement, so applicants are not required to provide non-federal matching funds as a condition of award. The activity category is labeled "Food and Nutrition Health" in the source data, while the CFDA listing (93.847) places it under Diabetes, Digestive, and Kidney Diseases Extramural Research, reflecting NIH institute alignment and the broader health research mission that includes kidney and related organ injury and repair processes.
Eligibility is broad across U.S.-based organizations and governmental entities, including public and private institutions of higher education, nonprofits (including 501(c)(3) organizations), for-profit organizations other than small businesses, small businesses, and a wide range of state, county, city, township, special district, and tribal government entities. The announcement also explicitly includes a variety of mission-relevant institution types such as HBCUs, Hispanic-serving institutions, AANAPISI institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and faith-based or community-based organizations, among others. Foreign institutions and non-U.S. components of U.S. organizations are not eligible to apply; however, foreign components are allowed as defined in the NIH Grants Policy Statement, which generally means discrete elements of the project may be performed outside the U.S. under NIH rules when well-justified and appropriately managed.
Key dates in the record show the FOA was posted and created on October 22, 2013, with an original and current closing date of March 19, 2014, and an archive date of April 19, 2014. That means the opportunity is historical rather than currently open, but it still provides a useful snapshot of NIH priorities at the time and a model for how NIH frames consortium-building around measurement science for fibrosis in kidney, marrow, and urological disease areas. The sponsoring agency is the National Institutes of Health, and the full announcement was hosted on the NIH grants guide under the provided link. For access or technical issues, the contact listed is the NIH Office of Extramural Research webmaster, indicating the posting is part of NIH's standard funding announcement system rather than a single-institute standalone web page.
Frequently Asked Questions (FAQs)
What is RFA-DK-13-026?
RFA-DK-13-026 is an NIH discretionary funding opportunity announcement (FOA) that solicits applications to build a research consortium focused on developing new ways to detect and measure organ fibrosis.
What is the main purpose of this funding opportunity?
The stated purpose is to establish a consortium that advances novel methods for identifying, quantifying, staging, and tracking fibrosis over time, with the broader goal of improving comparability across studies and clinical settings and supporting research and therapeutic development.
What research topic does this FOA focus on?
The scientific focus is organ fibrosis that develops after acute or chronic injury, especially in the kidney, bone marrow, prostate, and broader urological/urinary tract contexts.
Why is fibrosis measurement emphasized in this program?
The FOA highlights that fibrosis is a common and often decisive driver of long-term organ dysfunction, but it can be difficult to quantify accurately, monitor longitudinally, or compare across different studies and clinical environments. The program emphasizes novel detection and measurement approaches to address those gaps.
What kinds of approaches are considered responsive to the FOA?
Based on the description, the FOA signals interest in novel methods such as tools, technologies, biomarkers, imaging approaches, and analytical frameworks that improve how fibrosis is detected, measured, staged, and monitored, and how it might be used as a research endpoint.
What is the funding mechanism used for this opportunity?
The award mechanism is a U01 cooperative agreement.
What does a U01 cooperative agreement imply for awardees?
A U01 cooperative agreement typically means NIH expects substantial scientific and/or programmatic involvement during the project period. In practice, this aligns with a consortium model where multiple awardees coordinate on shared goals, harmonize methods, and contribute to common resources or standards rather than operating as fully independent projects.
Is this opportunity intended to support a single project or a consortium?
The FOA explicitly states its purpose is to establish a consortium. Applicants are therefore generally expected to address collaboration, shared goals, and contributions to consortium-wide milestones.
How many awards were anticipated?
The FOA anticipated making about 4 awards.
What was the estimated total funding level?
The estimated total funding level listed in the summary is $1,500,000.
What is the maximum funding amount per award?
The listed award ceiling is $250,000, indicating a maximum funding amount per award under the terms described in the provided summary.
Is cost sharing or matching required?
No. The summary states there is no cost sharing or matching requirement.
Who is the sponsoring agency?
The sponsoring agency is the National Institutes of Health (NIH).
What CFDA program listing is associated with this FOA?
The CFDA listing referenced is 93.847, identified as Diabetes, Digestive, and Kidney Diseases Extramural Research.
What activity category is shown in the source data?
The activity category is labeled as "Food and Nutrition Health" in the source data, alongside NIH institute alignment reflected by the CFDA listing.
What organizations are eligible to apply?
Eligibility is broad for U.S.-based entities and includes public and private institutions of higher education, nonprofits (including 501(c)(3) organizations), for-profit organizations other than small businesses, small businesses, and many types of U.S. state and local government entities (such as state, county, city, township, special district, and tribal governments).
Are minority-serving institutions and similar organization types included in eligibility?
Yes. The announcement explicitly includes a range of mission-relevant institution types, including HBCUs, Hispanic-serving institutions, AANAPISI institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and faith-based or community-based organizations, among others.
Are foreign institutions eligible to apply?
No. Foreign institutions and non-U.S. components of U.S. organizations are not eligible to apply, according to the provided summary.
Are foreign components allowed under this opportunity?
Yes. The summary notes that foreign components are allowed as defined in the NIH Grants Policy Statement, meaning discrete elements of the project may be performed outside the U.S. under NIH rules when appropriately justified and managed.
When was the FOA posted and created?
The record shows the FOA was posted and created on October 22, 2013.
What were the closing date(s) for the opportunity?
The original and current closing date shown in the record is March 19, 2014.
When was the opportunity archived?
The archive date listed is April 19, 2014.
Is this grant opportunity currently open?
No. Based on the closing and archive dates provided, this is a historical opportunity rather than a currently open solicitation.
Where was the full announcement hosted?
The full announcement was hosted on the NIH grants guide under the link referenced in the source description.
Who is listed as the contact for access or technical issues?
The contact listed is the NIH Office of Extramural Research webmaster, indicating the posting is part of NIH's standard funding announcement system.
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| Biomarkers for Diabetes Complications Non Invasive Measures in the Eye (DP3) Apply for RFA DK 13 027 Funding Number: RFA DK 13 027 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $1,000,000 |
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| George M. OBrien Urology Cooperative Research Centers Program (U54) Apply for RFA DK 13 020 Funding Number: RFA DK 13 020 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $1,000,000 |
| Seeding Collaborations for Translational Research to Discover and Develop New Therapies for Diseases and Conditions within NIDDKs Mission (Revisions) (R01) Apply for PAR 14 006 Funding Number: PAR 14 006 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $75,000 |
| Small Business Innovation Research to Develop New Therapeutics and Monitoring Technologies for Type 1 Diabetes (T1D) Towards an Artificial Pancreas (SBIR) (R43/R44) Apply for RFA DK 13 028 Funding Number: RFA DK 13 028 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Lead Optimization and Pre Clinical Development of Therapeutic Candidates for Diseases of Interest to NIDDK (STTR (R41/R42)) Apply for PA 14 054 Funding Number: PA 14 054 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Lead Optimization and Pre Clinical Development of Therapeutic Candidates for Diseases of Interest to the NIDDK (SBIR (R43/R44)) Apply for PA 14 055 Funding Number: PA 14 055 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Small Business Technology Transfer Research (STTR) to Develop New Diagnostic, Monitoring and Therapeutics Technologies for the Complications of Type 1 Diabetes (T1D) STTR (R41/R42) Apply for PA 14 059 Funding Number: PA 14 059 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Small Business Innovation Research (SBIR) to Develop New Diagnostic, Monitoring and Therapeutics Technologies for the Complications of Type 1 Diabetes (T1D) (SBIR (R43/R44)) Apply for PA 14 058 Funding Number: PA 14 058 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Research Using Subjects From Selected Type I Diabetes Clinical Studies (Living Biobank) (DP3) Apply for PAR 14 064 Funding Number: PAR 14 064 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Research Using Biosamples From Selected Type 1 Diabetes Clinical Studies (DP3) Apply for PAR 14 065 Funding Number: PAR 14 065 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Cystic Fibrosis Research and Translation Core Center (P30) Apply for RFA DK 13 007 Funding Number: RFA DK 13 007 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $750,000 |
| Systems for Health Apply for RFA 641 14 00002 Funding Number: RFA 641 14 00002 Agency: Ghana USAID Accra Category: Food and Nutrition Health Funding Amount: $68,000,000 |
| Limited Competition for the Continuation of the Diabetes Prevention Program Outcomes Study (DPPOS) (U01) Apply for RFA DK 14 501 Funding Number: RFA DK 14 501 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $400,000 |
| Limited Competition Continuation of the Type 2 Diabetes in Adolescents and Youth (TODAY) Study (U01) Apply for RFA DK 14 502 Funding Number: RFA DK 14 502 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $10,000,000 |
| Accelerating Medicines Partnership (AMP) in Type 2 Diabetes (U01) Apply for RFA DK 14 003 Funding Number: RFA DK 14 003 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $300,000 |
| Limited Competition for the Data Coordinating Center of Accelerating Medicines Partnership (AMP) in Type 2 Diabetes (U01) Apply for RFA DK 14 503 Funding Number: RFA DK 14 503 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $2,500,000 |
| Reagents for Glucagon and Incretin Research (R41/R42) Apply for PA 14 204 Funding Number: PA 14 204 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Reagents for Glucagon and Incretin Research (R43/R44) Apply for RFA DK 14 008 Funding Number: RFA DK 14 008 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Diabetes Impact Award Closed Loop Technologies Clinical, Physiological and Behavioral Approaches to Improve Type 1 Diabetes Outcomes (DP3) Apply for RFA DK 14 014 Funding Number: RFA DK 14 014 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
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