Opportunity Information: Apply for PA 13 359

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Nutrition and Alcohol Related Health Outcomes (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs 93.393 Cancer Cause and Prevention Research.
  • This funding opportunity was created on Oct 30, 2013 and posted on Sep 23, 2013.
  • Applicants must submit their applications by May 7, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) State governments Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Special district governments Independent school districts Native American tribal governments (Federally recognized) City or township governments Small businesses For profit organizations other than small businesses Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The Nutrition and Alcohol Related Health Outcomes (R01) opportunity (Funding Opportunity Number PA-13-359) is a National Institutes of Health (NIH) discretionary grant announcement that invited Research Project Grant (R01) applications focused on how nutrition influences alcohol-related health outcomes. The central aim was to encourage a wide range of studies that examine links between nutritional status, dietary patterns, nutrients, and other nutrition-related factors and the development, prevention, or treatment of harms associated with alcohol use. Projects could be designed in humans and/or animal models, with an emphasis on understanding mechanisms and relationships that connect diet and alcohol exposure to both behavioral and medical outcomes.

Scientifically, the scope was broad: applications were expected to investigate associations between nutrition and alcohol-related outcomes such as alcohol use disorder and longer-term chronic diseases affected by alcohol. Because the FOA explicitly mentions prevention and treatment, it supported work across the translational spectrum, including studies that clarify biological pathways (for example, how alcohol alters nutrient absorption or metabolism and how deficiencies or dietary interventions modify organ injury risk), as well as studies that test whether nutritional strategies can reduce alcohol-related damage or improve recovery. The inclusion of two CFDA program areas, 93.273 (Alcohol Research Programs) and 93.393 (Cancer Cause and Prevention Research), also signaled interest in alcohol-nutrition interactions relevant to cancer risk and prevention alongside broader alcohol-related health consequences.

From an administrative standpoint, this was an NIH grant mechanism under the R01 funding instrument, meaning it was intended for substantial, hypothesis-driven research projects with well-developed approaches, appropriate rigor, and clear significance. The announcement indicated there was no cost sharing or matching requirement, so applicants were not required to provide additional non-federal funds as a condition of award.

Eligibility was intentionally expansive. Eligible applicants included a wide range of U.S. organizations and governmental entities such as state, county, city or township governments; special district governments; independent school districts; public housing authorities/Indian housing authorities; public and state-controlled institutions of higher education; and private institutions of higher education. It also allowed nonprofit organizations both with and without 501(c)(3) status (other than institutions of higher education), small businesses, and for-profit organizations (including those other than small businesses). Beyond these categories, NIH explicitly listed additional eligible applicants such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations, eligible federal agencies, and regional organizations. Importantly, non-U.S. entities were eligible: foreign organizations and foreign institutions could apply, non-domestic components of U.S. organizations were eligible, and foreign components (as defined by NIH policy) were allowed, making the FOA open to international participation where scientifically justified.

In terms of timing, the opportunity was posted on September 23, 2013, created on October 30, 2013, and had an original and current closing date of May 7, 2017. It was archived on June 7, 2017, meaning it is no longer open for new submissions under that specific announcement. The full announcement was hosted on the NIH grants site, and the contact listed for access or linking issues was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

FAQs: Nutrition and Alcohol Related Health Outcomes (R01) (PA-13-359)

What is this funding opportunity?

This was a National Institutes of Health (NIH) discretionary grant announcement titled "Nutrition and Alcohol Related Health Outcomes (R01)." Its Funding Opportunity Number (FON) was PA-13-359, and it invited Research Project Grant (R01) applications.

What is the main goal of PA-13-359?

The central aim was to encourage a wide range of research studies examining how nutrition influences alcohol-related health outcomes. This included understanding links between nutritional status, dietary patterns, nutrients, and other nutrition-related factors and the development, prevention, or treatment of harms associated with alcohol use.

What kinds of research topics were within scope?

The scope was broad. Applications were expected to investigate associations between nutrition and alcohol-related outcomes such as alcohol use disorder and longer-term chronic diseases affected by alcohol. The announcement also supported prevention- and treatment-relevant research, spanning studies of underlying biological pathways through studies evaluating nutritional strategies to reduce harm or improve recovery.

Were both prevention and treatment studies allowed?

Yes. The FOA explicitly mentioned prevention and treatment, indicating that projects could focus on preventing alcohol-related harms and/or improving treatment and recovery outcomes using nutrition-related approaches.

Could studies focus on biological mechanisms?

Yes. The announcement emphasized understanding mechanisms and relationships connecting diet and alcohol exposure to behavioral and medical outcomes. Examples referenced included how alcohol alters nutrient absorption or metabolism and how nutrient deficiencies or dietary interventions may modify organ injury risk.

Were intervention-style nutrition strategies included?

Yes. In addition to mechanistic work, the FOA supported studies that test whether nutritional strategies can reduce alcohol-related damage or improve recovery.

What health outcomes were of interest?

The FOA emphasized alcohol-related harms broadly, including behavioral outcomes (such as alcohol use disorder) and medical outcomes (including longer-term chronic diseases affected by alcohol). It also signaled interest in alcohol-nutrition interactions relevant to cancer risk and prevention.

How did cancer-related research fit into this FOA?

The opportunity included CFDA program areas 93.273 (Alcohol Research Programs) and 93.393 (Cancer Cause and Prevention Research). This indicated interest in research on alcohol-nutrition interactions that may affect cancer risk and prevention, alongside other alcohol-related health consequences.

What grant mechanism was used?

This opportunity used the NIH Research Project Grant (R01) mechanism, intended for substantial, hypothesis-driven research projects with well-developed approaches, appropriate rigor, and clear significance.

Was cost sharing or matching required?

No. The announcement indicated there was no cost sharing or matching requirement. Applicants were not required to provide additional non-federal funds as a condition of award.

Who was eligible to apply?

Eligibility was expansive and included many types of U.S. organizations and governmental entities, as well as non-U.S. entities. The FOA listed eligible applicants across government, education, nonprofit, and for-profit sectors, and it also included various categories of minority-serving institutions and community-based organizations.

Which U.S. government entities were eligible?

Eligible U.S. governmental applicants included state, county, city or township governments; special district governments; independent school districts; public housing authorities/Indian housing authorities; eligible federal agencies; and regional organizations.

Were colleges and universities eligible?

Yes. Eligible applicants included public and state-controlled institutions of higher education and private institutions of higher education. The FOA also explicitly included specific categories of minority-serving institutions.

Which minority-serving institutions were specifically listed as eligible?

The FOA explicitly listed Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs).

Could nonprofits apply?

Yes. The FOA allowed nonprofit organizations with and without 501(c)(3) status (other than institutions of higher education).

Could for-profit organizations apply?

Yes. The FOA allowed small businesses and for-profit organizations (including those other than small businesses).

Were faith-based or community-based organizations eligible?

Yes. The FOA explicitly included faith-based or community-based organizations among eligible applicants.

Were foreign (non-U.S.) organizations eligible?

Yes. Non-U.S. entities were eligible. The FOA stated that foreign organizations and foreign institutions could apply, that non-domestic components of U.S. organizations were eligible, and that foreign components (as defined by NIH policy) were allowed.

Could projects include international or foreign components?

Yes. The FOA allowed foreign components (as defined by NIH policy) and also allowed non-domestic components of U.S. organizations, enabling international participation when scientifically justified.

Were both human and animal studies allowed?

Yes. Projects could be designed in humans and/or animal models, with an emphasis on understanding mechanisms and relationships connecting diet and alcohol exposure to behavioral and medical outcomes.

When was this opportunity posted and when did it close?

The opportunity was posted on September 23, 2013, created on October 30, 2013, and had an original and current closing date of May 7, 2017.

Is PA-13-359 still open for applications?

No. It was archived on June 7, 2017, which means it is no longer open for new submissions under that specific announcement.

Where was the full announcement hosted?

The full announcement was hosted on the NIH grants site.

Who was listed as the contact for access or linking issues?

The contact listed for access or linking issues was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

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