Opportunity Information: Apply for RFA GH 12 008

  • The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Operations Research (Implementation Science) for Strengthening Program Implementation through the Presidents Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067 Global AIDS.
  • This funding opportunity was created on Mar 28, 2012 and posted on Jan 3, 2012.
  • Applicants must submit their applications by Apr 16, 2012 Letter of Intent requested by March 1, 2012. Please see the full announcement document (click above) for futher information.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $10,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $500,000.00 in funding.
  • The number of recipients for this funding is limited to 15 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • PEPFAR local partners in countries with CDC GAP offices and with CDC GAP supported projects are eligible to apply. Eligibility is limited to public and nonprofit private institutions and agencies with host country investigators working in the approximately 40 PEPFAR supported countries with CDC Global AIDS Program (GAP) offices or CDC GAP supported projects. Applicants however, are not required to currently or previously have received PEPFAR funding to meet the below definition of a PEPFAR local partner.
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Opportunity Summary:

The Centers for Disease Control and Prevention (CDC) announced this discretionary funding opportunity, titled "Operations Research (Implementation Science) for Strengthening Program Implementation through the Presidents Emergency Plan for AIDS Relief (PEPFAR)," to support practical, real-world research that improves how HIV programs are delivered in PEPFAR-supported countries. The core intent is to generate actionable evidence that helps optimize service delivery and increase the population-level impact of HIV prevention, care, and treatment. In other words, the focus is not on basic science or discovering new drugs, but on learning what works best in routine program settings, how to fix bottlenecks, and how to strengthen implementation so that more people are reached, services are higher quality, and outcomes improve.

The program is framed as operations research and implementation science, meaning funded projects are expected to study program performance and implementation challenges in context, then produce findings that can be applied directly to strengthen PEPFAR-supported services. This aligns with Healthy People 2020s Global Health focus area by aiming to improve public health and support U.S. national security through stronger global disease detection, response, prevention, and control strategies. The opportunity is tied to the CDC Global AIDS Program (GAP) footprint and is meant to produce knowledge that can be used by ministries of health, local implementing partners, and CDC teams to refine strategies and maximize results.

Funding was offered through a cooperative agreement, which typically indicates substantial involvement from the federal agency during the project period (for example, technical collaboration, shared planning, and coordination with CDC priorities and country programs). The funding activity category is Health, and the relevant CFDA number is 93.067 (Global AIDS). The estimated total funding amount was $10,000,000, with an expectation of around 15 awards. Individual awards were projected to range from a floor of $200,000 to a ceiling of $500,000. No cost sharing or matching was required, which reduces the financial burden on applicants and can make participation more feasible for local institutions.

Eligibility was targeted and country-focused. Applicants needed to be PEPFAR local partners operating in countries with CDC GAP offices or with CDC GAP-supported projects. Eligibility was limited to public institutions and nonprofit private institutions and agencies that have host-country investigators working in roughly 40 PEPFAR-supported countries where CDC GAP has a presence or supports projects. Importantly, applicants were not required to currently or previously receive PEPFAR funding in order to qualify as a PEPFAR local partner, which suggests the announcement aimed to broaden participation beyond existing PEPFAR awardees while still ensuring the work was grounded in CDC-supported country platforms and local leadership.

The timeline reflects a short application window typical of time-sensitive program-driven research. The opportunity was posted January 3, 2012, with an original closing date of March 29, 2012, later extended to April 16, 2012. A letter of intent was requested by March 1, 2012, signaling that CDC wanted early visibility into proposed projects and alignment with program priorities before full applications were submitted. The archive date was May 16, 2012, indicating the opportunity is no longer active.

For access and administrative support, applicants were directed to the Full Announcement document (noting that the additional information link provided was not active). Technical assistance for accessing the announcement electronically was available through the CDC Procurement and Grants Office (PGO), Technical Information Management Section (TIMS), at 770-488-2700. Overall, this opportunity was designed to fund locally grounded, program-relevant research that can quickly translate into stronger HIV service delivery and better outcomes across PEPFAR-supported settings.

Frequently Asked Questions (FAQs)

1) What is the name of this CDC funding opportunity?

The opportunity is titled "Operations Research (Implementation Science) for Strengthening Program Implementation through the Presidents Emergency Plan for AIDS Relief (PEPFAR)."

2) What is the main purpose of this grant?

The purpose is to fund practical, real-world operations research and implementation science that improves how HIV programs are delivered in PEPFAR-supported countries. The intent is to generate actionable evidence that can be used to optimize service delivery and increase the population-level impact of HIV prevention, care, and treatment.

3) What kinds of research does this opportunity emphasize?

It emphasizes operations research and implementation science focused on program performance in routine settings. Projects are expected to study implementation challenges in context (for example, bottlenecks in service delivery) and produce findings that can be applied directly to strengthen PEPFAR-supported services.

4) What is not the focus of this opportunity?

This opportunity is not focused on basic science or discovering new drugs. The focus is on learning what works best in real program environments and how to improve implementation to reach more people, improve service quality, and strengthen outcomes.

5) How is this opportunity connected to PEPFAR and CDC programs?

The work is tied to PEPFAR-supported settings and aligned with the CDC Global AIDS Program (GAP) footprint. The expectation is that results will be useful to ministries of health, local implementing partners, and CDC teams to refine strategies and maximize results in countries where CDC GAP offices are present or where CDC GAP supports projects.

6) What is the funding mechanism used for this opportunity?

Funding was offered through a cooperative agreement, which typically means the federal agency (CDC) has substantial involvement during the project period, such as technical collaboration, shared planning, and coordination with CDC priorities and country programs.

7) What is the funding activity category and CFDA number?

The funding activity category is Health. The CFDA number listed is 93.067 (Global AIDS).

8) How much total funding was estimated for this opportunity?

The estimated total funding amount was $10,000,000.

9) How many awards were expected?

The announcement projected approximately 15 awards.

10) What was the expected funding range per award?

Individual awards were projected to range from a floor of $200,000 to a ceiling of $500,000.

11) Was cost sharing or matching required?

No. The announcement stated that no cost sharing or matching was required.

12) Who was eligible to apply?

Eligibility was limited to PEPFAR local partners operating in countries with CDC GAP offices or with CDC GAP-supported projects. Eligible applicants included public institutions and nonprofit private institutions and agencies that have host-country investigators working in roughly 40 PEPFAR-supported countries where CDC GAP has a presence or supports projects.

13) Did applicants need to already receive PEPFAR funding to be eligible?

No. Applicants were not required to currently or previously receive PEPFAR funding in order to qualify as a PEPFAR local partner, based on the information provided.

14) What is meant by "host-country investigators" in the eligibility description?

The eligibility description specifies that applicants must have host-country investigators working in the PEPFAR-supported countries where CDC GAP has a presence or supports projects, indicating that local, in-country leadership and engagement are central to the opportunity.

15) What were the key dates for this funding opportunity?

The opportunity was posted on January 3, 2012. The original closing date was March 29, 2012, and it was later extended to April 16, 2012. A letter of intent was requested by March 1, 2012. The archive date was May 16, 2012.

16) Was a letter of intent required?

A letter of intent was requested by March 1, 2012. This indicated CDC wanted early visibility into proposed projects and their alignment with program priorities before full applications were submitted.

17) Is this opportunity still open?

No. The archive date was May 16, 2012, indicating the opportunity is no longer active.

18) What public health or policy framework does this opportunity align with?

The program aligns with Healthy People 2020's Global Health focus area by aiming to improve public health and support U.S. national security through stronger global disease detection, response, prevention, and control strategies, as described in the opportunity summary.

19) Where were applicants directed to find the official details?

Applicants were directed to the Full Announcement document for access and administrative support. The information provided noted that the additional information link referenced in the opportunity materials was not active.

20) Who could applicants contact for technical help accessing the announcement electronically?

Technical assistance was available through the CDC Procurement and Grants Office (PGO), Technical Information Management Section (TIMS), at 770-488-2700.

21) What is the intended use of results from funded projects?

Findings were intended to be directly applicable to strengthening PEPFAR-supported HIV services, helping ministries of health, local implementing partners, and CDC teams refine strategies, remove bottlenecks, and improve service reach, quality, and outcomes.

22) What geographic scope was implied for this opportunity?

The opportunity was country-focused and linked to the CDC GAP footprint in roughly 40 PEPFAR-supported countries where CDC GAP has a presence or supports projects.

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Previous opportunity: Regional Integrated Pest Management Competitive Grants Program Northeastern Region

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