Opportunity Information: Apply for PA 13 060
Apply for PA 13 060
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Pain in Aging (R03)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.866 Aging Research.
- This funding opportunity was created on Dec 20, 2012 and posted on Dec 20, 2012.
- Applicants must submit their applications by Jan 7, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $50,000.00 in funding.
- Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Public housing authorities/Indian housing authorities Others (see text field entitled Additional Information on Eligibility for clarification) County governments For profit organizations other than small businesses Small businesses Native American tribal governments (Federally recognized) Special district governments City or township governments Public and State controlled institutions of higher education Independent school districts.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Pain in Aging (R03) funding opportunity (PA-13-060) is a National Institutes of Health (NIH) small grant program designed to support focused, early-stage, or pilot research projects that look at pain through an aging lens. The central aim is to improve understanding of how pain is experienced, processed, assessed, and treated as people grow older. Projects can center directly on older adult populations, compare pain mechanisms or outcomes across age groups, or examine age-related changes that shape pain perception and disability. The opportunity also welcomes work that tests or refines pain treatment and self-management approaches specifically for older adults, recognizing that aging often comes with added complexity in medical decision-making.
The FOA highlights three priority areas. First, it encourages studies on mechanisms and predictors of pain in aging, which can include biological pathways (genetic, molecular, neurobiological), as well as clinical and psychosocial factors that may drive differences in pain severity, persistence, or functional impact in later life. Second, it seeks the development and evaluation of pain assessment tools tailored to older adults or to older model organisms, reflecting the reality that common pain measures may not perform the same way in people with cognitive impairment, sensory changes, communication barriers, or different symptom presentations. Third, it supports the development and evaluation of pain management strategies for older adults, with special attention to the real-world challenge of treating pain in patients who have multiple chronic conditions at the same time. This emphasis fits the clinical reality that polypharmacy risks, contraindications, frailty, and competing health priorities can all complicate standard pain care.
Methodologically, the program is intentionally broad. Applicants can propose human subjects research, including clinical, behavioral, psychological, or social studies, as well as animal research, with an explicit interest in aged animal models when appropriate. Outcomes and approaches can span from basic science and translational studies to clinical and community-focused investigations, as long as the work meaningfully addresses pain in the context of aging. The overall expectation is that even a small, time-limited R03 project can generate valuable preliminary data, evaluate feasibility, or produce tools and insights that set up larger follow-on studies.
From an administrative and funding standpoint, this is a discretionary grant opportunity using the NIH R03 small grant mechanism. The award ceiling listed for this opportunity is $50,000, and there is no cost sharing or matching requirement. The opportunity was posted and created on December 20, 2012, with an original and final closing date of January 7, 2016, and an archive date of February 7, 2016, meaning the specific announcement is no longer active but remains useful as a reference point for similar NIH pain-and-aging initiatives.
Eligibility is broad and includes many types of U.S. and non-U.S. organizations. Eligible applicants include public and private institutions of higher education, nonprofits (both 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (excluding small businesses in one category but also listing small businesses separately as eligible), state and local governments (including county and city/township governments), independent school districts, special district governments, and public or Indian housing authorities. The eligibility list also explicitly includes tribal governments and tribal organizations, Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, AANAPISI institutions, tribally controlled colleges and universities (TCCUs), faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and foreign (non-U.S.) entities. The sponsoring agency is the National Institutes of Health, and the full announcement was hosted on the NIH grants website under PA-13-060.
Frequently Asked Questions (FAQs): Pain in Aging (R03) - PA-13-060
What is the Pain in Aging (R03) funding opportunity (PA-13-060)?
PA-13-060 is a National Institutes of Health (NIH) small grant funding opportunity using the R03 mechanism. It is designed to support focused, early-stage, or pilot research projects that study pain in the context of aging.
What is the central goal of this opportunity?
The central aim is to improve understanding of how pain is experienced, processed, assessed, and treated as people grow older, including how aging-related changes can affect pain perception, disability, and care decisions.
What kinds of projects are a good fit for this FOA?
Projects that are focused and time-limited are a good fit, especially studies that can generate preliminary data, test feasibility, develop or evaluate tools, or produce insights that support follow-on research. The FOA supports work ranging from basic and translational research to clinical and community-focused investigations, as long as the work meaningfully addresses pain through an aging lens.
Does the research have to involve older adults directly?
No. Projects may focus directly on older adult populations, compare pain mechanisms or outcomes across age groups, or examine age-related changes that influence pain perception and disability.
Are studies on pain treatment or self-management for older adults allowed?
Yes. The opportunity welcomes studies that test or refine pain treatment and self-management approaches specifically for older adults, including work that considers the added complexity often present in medical decision-making with aging.
What are the three priority areas highlighted in the FOA?
The FOA highlights three priority areas: (1) mechanisms and predictors of pain in aging, (2) development and evaluation of pain assessment tools tailored to older adults or older model organisms, and (3) development and evaluation of pain management strategies for older adults, including the challenges of managing pain when multiple chronic conditions are present.
What does the FOA mean by "mechanisms and predictors of pain in aging"?
This area can include biological pathways (genetic, molecular, neurobiological) as well as clinical and psychosocial factors that may help explain differences in pain severity, persistence, or functional impact in later life.
What types of pain assessment tool projects are encouraged?
The FOA encourages development and evaluation of pain assessment tools tailored to older adults or to older model organisms. This reflects the concern that common pain measures may not work the same way in older adults who may have cognitive impairment, sensory changes, communication barriers, or different symptom presentations.
What types of pain management strategy projects are encouraged?
The FOA supports development and evaluation of pain management strategies for older adults, with special attention to real-world clinical complexity such as multiple chronic conditions, polypharmacy risk, contraindications, frailty, and competing health priorities that can complicate standard pain care.
What research methods and study types are allowed?
The program is intentionally broad. Applicants can propose human subjects research (including clinical, behavioral, psychological, or social studies) and animal research, with explicit interest in aged animal models when appropriate.
Is this opportunity limited to basic science, or can it include clinical/community research?
It can include both. The FOA allows approaches spanning basic science, translational studies, clinical research, and community-focused investigations, as long as the project addresses pain in the context of aging.
What is the grant mechanism used for this opportunity?
This FOA uses the NIH R03 small grant mechanism, which is typically used for small, focused, and time-limited projects such as pilot studies, feasibility work, or preliminary tool development/evaluation.
What is the award ceiling for this opportunity?
The award ceiling listed for this opportunity is $50,000.
Is cost sharing or matching required?
No. The FOA states there is no cost sharing or matching requirement.
Is this grant opportunity still active?
No. The opportunity is no longer active. It was posted/created on December 20, 2012, had an original and final closing date of January 7, 2016, and an archive date of February 7, 2016. It remains useful as a reference for similar NIH pain-and-aging initiatives.
Who is the sponsoring agency?
The sponsoring agency is the National Institutes of Health (NIH).
Where was the full announcement hosted?
The full announcement was hosted on the NIH grants website under the identifier PA-13-060.
Who is eligible to apply?
Eligibility is broad and includes many types of U.S. and non-U.S. organizations, including higher education institutions, nonprofits, for-profits, government entities, tribal governments and organizations, and foreign (non-U.S.) entities.
Are U.S. colleges and universities eligible?
Yes. Eligible applicants include public and private institutions of higher education.
Are nonprofit organizations eligible?
Yes. The eligibility list includes nonprofits (both 501(c)(3) and certain non-501(c)(3) entities).
Are for-profit organizations eligible?
Yes. For-profit organizations are included as eligible applicants, and small businesses are also listed separately as eligible in the provided eligibility description.
Are state and local governments eligible?
Yes. The eligibility list includes state governments and local governments, including county governments and city or township governments.
Are school districts and special district governments eligible?
Yes. Independent school districts and special district governments are explicitly listed as eligible.
Are public or Indian housing authorities eligible?
Yes. Public and Indian housing authorities are included in the eligibility list.
Are tribal governments and tribal organizations eligible?
Yes. The eligibility list explicitly includes tribal governments and tribal organizations.
Are minority-serving institutions eligible (such as HBCUs and Hispanic-serving institutions)?
Yes. The eligibility list explicitly includes Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, AANAPISI institutions, and tribally controlled colleges and universities (TCCUs).
Are faith-based or community-based organizations eligible?
Yes. Faith-based and community-based organizations are explicitly listed as eligible.
Are regional organizations eligible?
Yes. Regional organizations are included in the eligibility list.
Are U.S. territories or possessions eligible?
Yes. U.S. territories or possessions are explicitly listed as eligible.
Are foreign (non-U.S.) organizations eligible?
Yes. Foreign (non-U.S.) entities are explicitly listed as eligible applicants.
What is the main thematic focus that ties eligible projects together?
The unifying theme is pain research viewed through an aging lens, including how aging influences pain mechanisms, assessment, outcomes (such as disability), and management in real-world settings.
Does the FOA emphasize research involving complex older patients?
Yes. A stated emphasis is the challenge of treating pain in older adults with multiple chronic conditions, including issues like polypharmacy risks, contraindications, frailty, and competing health priorities.
Are aged animal models specifically encouraged?
Yes. The FOA allows animal research and explicitly notes interest in aged animal models when appropriate.
What is the expected value of a small R03 project under this program?
The FOA expects that even a small, time-limited R03 project can generate valuable preliminary data, evaluate feasibility, or produce tools and insights that position a research area for larger follow-on studies.
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