Opportunity Information: Apply for RFA AI 09 027
Apply for RFA AI 09 027
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Partnerships for Biodefense Food and Water borne Diseases (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.856 Microbiology and Infectious Diseases Research.
- This funding opportunity was created on Jun 24, 2009 and posted on Jun 23, 2009.
- Applicants must submit their applications by Sep 23, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $7,300,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $750,000.00 in funding.
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Private institutions of higher education Special district governments Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) State governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education For profit organizations other than small businesses City or township governments County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
Partnerships for Biodefense Food and Water borne Diseases (R01) is a National Institutes of Health (NIH) funding opportunity issued by the National Institute of Allergy and Infectious Diseases (NIAID) focused on strengthening biodefense-related medical countermeasure research for food- and water-borne threats. The program invites research projects that aim to develop practical tools to prevent, detect, and treat illness caused by NIAID Category B priority pathogens and toxins that could be introduced through food or water systems. In plain terms, the FOA is looking for R01-scale research that can move candidate therapeutics, immunotherapeutics, medical diagnostics, and broad-spectrum vaccines forward against these specific biodefense-relevant agents, with the expectation that funded work will contribute to preparedness and response capabilities.
The scientific scope emphasizes product-oriented research rather than purely descriptive studies. Applications are expected to center on development activities that can plausibly advance a countermeasure: drugs and other therapeutics to treat infection or intoxication, immunotherapeutics such as antibody-based approaches or immune-modulating interventions, diagnostic tests that can identify an agent quickly and reliably, and broad-spectrum vaccines that could protect against one or multiple relevant food- or water-borne agents. The FOA ties eligibility of targets to NIAIDs Category B food and water borne priority pathogens and toxins list (referenced in the announcement), signaling that applicants should align their rationale, models, endpoints, and development plans to those prioritized agents and to biodefense preparedness needs.
The mechanism of support is the NIH R01 Research Project Grant, which typically supports investigator-initiated research projects with defined aims and milestones. This particular FOA indicates that award size and project duration may vary depending on the proposed work, reflecting that different countermeasure development pathways can require very different levels of effort, timelines, and resources. While an R01 does not automatically imply late-stage product development, the intent here is clearly translational and development-driven within the R01 structure.
NIAID projected a total commitment of about $7.3 million in total costs in FY2010 for this FOA, with an anticipated five to ten awards. The actual number of awards would depend on available funds and on the number and quality of applications received. The announcement lists an award ceiling of $750,000, which effectively signals an upper bound on the budget level expected under this call (though actual award amounts would depend on project scope and NIAID decisions). Applicants should therefore plan budgets that fit within that ceiling and match the development activities proposed, including any necessary assay development, animal studies, preclinical proof-of-concept work, or diagnostic validation steps appropriate to the stage of the project.
Eligibility is broad and includes many organizational types across the public, private, nonprofit, and academic sectors. Eligible applicants include small businesses, for-profit organizations (other than small businesses), nonprofit organizations (including those with and without 501(c)(3) status), public and private institutions of higher education, and a wide range of governmental entities (state, county, city/township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities). The FOA also explicitly includes tribal governments and tribal organizations, as well as capacity-building and community-focused institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and Tribally Controlled Colleges and Universities (TCCUs). It further allows eligible federal agencies and non-U.S. entities (foreign organizations), regional organizations, and U.S. territories or possessions. There is no cost sharing or matching requirement, which is consistent with typical NIH research grants and lowers barriers for applicants who might not have access to non-federal matching funds.
Key administrative details from the source information are as follows: the Funding Opportunity Number is RFA-AI-09-027, and the activity falls under CFDA 93.856 (Microbiology and Infectious Diseases Research). It was posted June 23, 2009, created June 24, 2009, and had an application closing date of September 23, 2009 (with an archive date of October 24, 2009), meaning it was a time-limited solicitation rather than an open-ended standing program announcement. For applicants or researchers looking up the original full text, the FOA is hosted through the NIH grants guide webpage referenced in the announcement, and NIH Office of Extramural Research (OER) webmaster contact information is provided for technical access issues.
Overall, this grant opportunity was designed to fund a small portfolio of R01 projects that directly contribute to biodefense readiness by advancing countermeasures for high-priority food- and water-borne Category B agents. Strong applications under a call like this would be expected to show clear alignment with the priority pathogen/toxin list, a credible development plan toward a usable product or validated tool, and a scope that fits both the R01 mechanism and the stated funding limits and award expectations.
FAQs: Partnerships for Biodefense Food and Water borne Diseases (R01)
What is this funding opportunity?
This is an NIH funding opportunity titled "Partnerships for Biodefense Food and Water borne Diseases (R01)." It is issued by the National Institute of Allergy and Infectious Diseases (NIAID) to support biodefense-related medical countermeasure research focused on food- and water-borne threats.
Which NIH institute is sponsoring this opportunity?
The sponsoring institute is the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH).
What is the goal of the program?
The goal is to strengthen biodefense preparedness by funding R01-scale projects that develop practical tools to prevent, detect, and treat illness caused by certain high-priority food- and water-borne pathogens and toxins.
What types of threats are in scope?
The focus is on NIAID Category B priority pathogens and toxins that could be introduced through food or water systems. Projects are expected to align their targets and rationale to NIAID's Category B food and water borne priority pathogen/toxin list referenced by the announcement.
What types of projects are encouraged?
The FOA emphasizes product-oriented, translational research that can plausibly advance a medical countermeasure or validated tool. The solicitation is looking for development-driven projects rather than purely descriptive studies.
What kinds of countermeasures or tools does the FOA mention?
The FOA highlights development of: (1) therapeutics (drugs and other treatments) to treat infection or intoxication, (2) immunotherapeutics such as antibody-based approaches or immune-modulating interventions, (3) medical diagnostics that identify an agent quickly and reliably, and (4) broad-spectrum vaccines that could protect against one or multiple relevant food- or water-borne agents.
Does the FOA support basic descriptive research?
The scientific scope is described as product-oriented and development-focused. Based on the information provided, purely descriptive studies are not the emphasis; applications are expected to center on development activities that advance a countermeasure or practical tool.
What grant mechanism is used for this opportunity?
The mechanism is the NIH R01 Research Project Grant.
What does "R01" imply for project structure?
An R01 typically supports investigator-initiated research with defined aims and milestones. In this FOA, the intent is translational and development-driven within the R01 structure.
How many awards were anticipated?
NIAID anticipated approximately five to ten awards, depending on available funds and the number and quality of applications received.
What was the projected total funding level?
NIAID projected a total commitment of about $7.3 million in total costs in FY2010 for this FOA.
Is there a budget cap (award ceiling)?
Yes. The announcement lists an award ceiling of $750,000, signaling an upper bound on the budget level expected under this call. Actual award amounts would depend on project scope and NIAID decisions.
How long can projects run?
The FOA indicates that award size and project duration may vary depending on the proposed work, recognizing that different countermeasure development pathways can require different timelines and resources.
What kinds of activities might be included in the proposed work?
Based on the description, budgets and workplans could include activities such as assay development, animal studies, preclinical proof-of-concept work, or diagnostic validation steps appropriate to the stage of the project.
Who is eligible to apply?
Eligibility is broad. Eligible applicants include small businesses; for-profit organizations (other than small businesses); nonprofit organizations (with or without 501(c)(3) status); public and private institutions of higher education; and many governmental entities (state, county, city/township, special district, independent school districts, and public housing authorities/Indian housing authorities).
Are tribal entities eligible?
Yes. The FOA explicitly includes tribal governments and tribal organizations as eligible applicants.
Are minority-serving and capacity-building institutions included?
Yes. The FOA explicitly includes institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and Tribally Controlled Colleges and Universities (TCCUs).
Can federal agencies apply?
Yes. The FOA allows eligible federal agencies.
Are non-U.S. (foreign) organizations eligible?
Yes. The FOA states that non-U.S. entities (foreign organizations) are eligible. It also allows regional organizations and U.S. territories or possessions.
Is cost sharing or matching required?
No. The FOA states there is no cost sharing or matching requirement.
What is the Funding Opportunity Number?
The Funding Opportunity Number is RFA-AI-09-027.
What CFDA number is associated with this opportunity?
The activity falls under CFDA 93.856, Microbiology and Infectious Diseases Research.
When was the opportunity posted?
It was posted on June 23, 2009, and created on June 24, 2009.
What was the application due date?
The application closing date was September 23, 2009.
Is this opportunity still active?
Based on the provided dates, it was a time-limited solicitation. The archive date was October 24, 2009.
Where can someone find the original FOA text?
The FOA is hosted through the NIH grants guide webpage referenced in the announcement.
Who should be contacted for technical issues accessing the FOA?
The NIH Office of Extramural Research (OER) webmaster contact information is provided in the announcement for technical access issues.
What makes an application a strong fit for this FOA based on the description?
A strong fit would show clear alignment with NIAID's Category B food- and water-borne priority pathogens/toxins, present a credible development plan toward a usable countermeasure or validated tool, and propose a scope that fits the R01 mechanism and the stated funding limits and award expectations.
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