Opportunity Information: Apply for RFA AI 10 017
Apply for RFA AI 10 017
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Partnerships for Next Generation Biodefense Diagnostics (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.856 Microbiology and Infectious Diseases Research.
- This funding opportunity was created on Jul 8, 2010 and posted on Jul 8, 2010.
- Applicants must submit their applications by Nov 4, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $750,000.00 in funding.
- Eligible applicants include: Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education State governments Others (see text field entitled Additional Information on Eligibility for clarification) City or township governments Small businesses Independent school districts For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Partnerships for Next Generation Biodefense Diagnostics (R01) funding opportunity (RFA-AI-10-017) is a discretionary NIH grant program run through the National Institute of Allergy and Infectious Diseases (NIAID). Its main goal is to push early stage, product-focused diagnostic development for biodefense-relevant needs, specifically supporting projects that can demonstrate a clear proof of concept for "next generation" diagnostic products. A key feature of this announcement is its technical scope: it is aimed at diagnostics approaches that do not rely on nucleic acid amplification (so it is not intended for typical PCR-based or other amplification-driven molecular tests). Instead, applicants are expected to propose alternative diagnostic strategies and show convincing early evidence that the approach can work as a viable diagnostic product concept.
The program uses the NIH R01 mechanism, meaning it is structured as a research project grant, but the emphasis here is strongly on early product development rather than purely basic research. In practice, that usually implies applicants should frame their work around a development plan with tangible milestones and performance targets, such as prototype development, analytical feasibility, preliminary validation, workflow design considerations, or other steps that reduce technical risk and move an idea closer to a usable diagnostic. The title also signals an interest in partnerships, which commonly points to collaborative arrangements that combine complementary capabilities (for example, academic innovation paired with industry engineering, manufacturing know-how, regulatory experience, or access to relevant specimens and testing environments).
In terms of funding, NIAID planned to commit about $9 million in total costs in fiscal year 2011 to support an anticipated 7 to 10 awards under this FOA. The listed award ceiling is $750,000, setting an upper bound on the size of an individual award under the announcement as published in the provided data. There is no cost sharing or matching requirement, which lowers the barrier for applicants who might not have non-federal funds available to contribute.
The opportunity falls under the Health funding activity category and is tied to CFDA number 93.856 (Microbiology and Infectious Diseases Research). The announcement was posted July 8, 2010, with an original and current closing date of November 4, 2010, and an archive date of December 5, 2010, indicating it was a time-limited solicitation rather than an open-ended program announcement.
Eligibility is broad and includes many common applicant types across government, academia, nonprofit, and the private sector. Eligible applicants include public and private institutions of higher education, nonprofits with or without 501(c)(3) status (with the note that the category excludes institutions of higher education where specified), for-profit organizations (including small businesses and for-profits other than small businesses), and multiple levels of government (state, county, city/township, special district governments, and independent school districts). The eligibility language also extends to tribal entities (federally recognized tribal governments as well as other tribal organizations), public housing authorities/Indian housing authorities, and a range of institution types often called out in federal solicitations, such as Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based and community-based organizations, regional organizations, and U.S. territories or possessions. Notably, non-U.S. entities (foreign organizations) are also listed as eligible in the provided eligibility information, which can open the door to international teams when scientifically justified and consistent with NIH rules.
For reference and official details, the FOA was made available through the NIH Grants Guide at the link provided (http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-10-017.html). The contact information included is for technical issues accessing or linking to the announcement, directed to the NIH Office of Extramural Research (OER) webmaster (FBOWebmaster@OD.NIH.GOV).
FAQs: Partnerships for Next Generation Biodefense Diagnostics (R01) - RFA-AI-10-017
What is the name of this funding opportunity?
The opportunity is titled "Partnerships for Next Generation Biodefense Diagnostics (R01)" and is published under FOA number RFA-AI-10-017.
Which agency and institute run this grant program?
This is an NIH discretionary grant program run through the National Institute of Allergy and Infectious Diseases (NIAID).
What is the main goal of this program?
The main goal is to advance early-stage, product-focused diagnostic development for biodefense-relevant needs, with projects expected to demonstrate a clear proof of concept for "next generation" diagnostic products.
What makes the technical scope of this FOA different from typical molecular diagnostic solicitations?
A defining feature is that the FOA is aimed at diagnostic approaches that do not rely on nucleic acid amplification. It is not intended for typical PCR-based tests or other amplification-driven molecular diagnostics. Applicants are expected to propose alternative diagnostic strategies and provide convincing early evidence that the approach can work as a viable diagnostic product concept.
What grant mechanism is used for this opportunity?
The FOA uses the NIH R01 mechanism, which is a research project grant mechanism. In this specific announcement, the emphasis is strongly on early product development rather than purely basic research.
What kind of work is NIAID expecting under an R01 for this FOA?
Applicants are generally expected to frame the project around a development plan with tangible milestones and performance targets. Examples mentioned include prototype development, analytical feasibility, preliminary validation, workflow design considerations, and other steps that reduce technical risk and move an idea closer to a usable diagnostic.
Does the FOA encourage partnerships or collaboration?
Yes. The title signals an interest in partnerships, commonly pointing to collaborative arrangements that combine complementary capabilities. Examples include academic innovation paired with industry engineering, manufacturing know-how, regulatory experience, or access to relevant specimens and testing environments.
How much funding did NIAID plan to commit to this program?
NIAID planned to commit about $9 million in total costs in fiscal year 2011 for this FOA.
How many awards were anticipated?
The FOA anticipated approximately 7 to 10 awards.
What is the maximum award size under this announcement?
The listed award ceiling is $750,000, which sets an upper bound on the size of an individual award under the published announcement data.
Is cost sharing or matching required?
No. The FOA states there is no cost sharing or matching requirement.
What is the funding activity category?
The opportunity falls under the Health funding activity category.
What CFDA number is associated with this opportunity?
The FOA is tied to CFDA number 93.856, titled "Microbiology and Infectious Diseases Research."
When was the FOA posted?
The announcement was posted on July 8, 2010.
What were the closing date and archive date?
The original and current closing date is listed as November 4, 2010. The archive date is December 5, 2010, indicating it was a time-limited solicitation rather than an open-ended program announcement.
Who is eligible to apply?
Eligibility is broad and includes public and private institutions of higher education; nonprofits with or without 501(c)(3) status (with the note that the category excludes institutions of higher education where specified); for-profit organizations (including small businesses and for-profits other than small businesses); and multiple levels of government (state, county, city/township, special district governments, and independent school districts).
Are tribal entities eligible?
Yes. Eligible applicants include federally recognized tribal governments as well as other tribal organizations. The eligibility list also includes public housing authorities/Indian housing authorities.
Are institutions like HBCUs and Hispanic Serving Institutions included in eligibility?
Yes. The eligibility language calls out a range of institution types often included in federal solicitations, including Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based and community-based organizations, regional organizations, and U.S. territories or possessions.
Are non-U.S. (foreign) organizations eligible to apply?
Yes. Non-U.S. entities (foreign organizations) are listed as eligible in the provided eligibility information, which can support international teams when scientifically justified and consistent with NIH rules.
Where can applicants find the official FOA text?
The FOA was made available through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-10-017.html
Who should be contacted for technical issues accessing or linking to the announcement?
For technical issues accessing or linking to the announcement, the contact provided is the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
Is this opportunity focused on basic research or product development?
While it uses the R01 research project mechanism, the stated emphasis is strongly on early-stage, product-focused diagnostic development, including proof-of-concept and milestones that move an approach closer to a usable diagnostic product.
Does this FOA target a specific type of diagnostic approach?
Yes. It targets "next generation" diagnostic concepts for biodefense-relevant needs and specifically emphasizes approaches that do not depend on nucleic acid amplification, with an expectation of convincing early evidence that the concept can function as a viable diagnostic product.
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