Opportunity Information: Apply for RFA CA 09 015
Apply for RFA CA 09 015
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Pathway to Independence Award in Cancer Nanotechnology Research (K99/R00)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.399 Cancer Control.
- This funding opportunity was created on Oct 8, 2009 and posted on Oct 8, 2009.
- Applicants must submit their applications by Dec 17, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
- Eligible applicants include: Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments City or township governments For profit organizations other than small businesses Private institutions of higher education Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) State governments.
- Other Eligible Applicants include the following Eligible Agencies of the Federal Government Regional Organizations U.S. Territory or Possession.
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Opportunity Summary:
The Pathway to Independence Award in Cancer Nanotechnology Research (K99/R00) is a National Cancer Institute (NCI), NIH funding opportunity designed to help promising postdoctoral researchers move more quickly from mentored training into stable, independent faculty-level research positions focused on cancer nanotechnology. It sits inside NCI's broader Alliance for Nanotechnology in Cancer program (nano.cancer.gov), which is built to accelerate nanotechnology-driven approaches to cancer prevention, detection, diagnosis, treatment, and control. In practical terms, this FOA is trying to grow and sustain a strong pipeline of early-career investigators who can build independent research programs at the intersection of cancer research and nanoscale science and engineering.
The award uses the NIH K99/R00 "Pathway to Independence" structure, meaning it is explicitly a two-phase transition mechanism. The first phase is a mentored period (the K99) intended for advanced postdoctoral or equivalent candidates who still benefit from structured supervision while they sharpen a research niche, expand technical skills, publish, and prepare for independence. The second phase is the independent period (the R00), which is meant to support the same investigator after they secure an independent research position, typically a tenure-track or equivalent role, allowing them to launch their own lab and research program with dedicated support earlier than would normally occur through standard NIH research grants alone. The core idea is to reduce the lag time between postdoctoral training and true independence, especially in a fast-moving, interdisciplinary field like cancer nanotechnology.
This FOA also connects to, and complements, other Alliance funding components that support a wider ecosystem for the field. Those related opportunities include Centers for Cancer Nanotechnology Excellence (CCNEs, U54 mechanism), Cancer Nanotechnology Platform Partnerships (CNPPs, U01 mechanism), and Cancer Nanotechnology Training Centers (CNTCs, R25 mechanism). Together, these programs are intended to provide infrastructure, collaborative platforms, and training environments, while the K99/R00 specifically targets the individual investigator transition so that new talent can plug into and strengthen the overall Alliance community.
From a funding and scale perspective, NCI indicated about $2 million in total costs committed for fiscal year 2010, and about $10 million projected over a five-year period for this specific initiative. The anticipated number of awards was relatively selective, with an expectation of roughly 8 to 10 awards under this FOA. The program is categorized as discretionary grant funding and is aligned with NIH cancer-related activity areas spanning cause and prevention, detection and diagnosis, treatment, and cancer control (CFDA 93.393, 93.394, 93.395, 93.399). There is no cost sharing or matching requirement, which typically makes the mechanism more straightforward for applicants and institutions.
Eligibility is broad on the institutional side, encompassing many organization types that can administer NIH grants, including public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status, with distinctions noted in the source listing), for-profit organizations (including small businesses), and various levels of government (city/township, county, and state). The listing also notes additional eligible entities such as eligible federal agencies, regional organizations, and U.S. territories or possessions, with the FOA text serving as the authoritative source for any clarifications. The opportunity was posted October 8, 2009, with an original and current closing date of December 17, 2009, and an archive date of January 17, 2010, indicating it is a historical announcement rather than a currently open competition.
Administrative details for reference include the Funding Opportunity Number RFA-CA-09-015 and the official title "Pathway to Independence Award in Cancer Nanotechnology Research (K99/R00)." The full announcement was hosted through the NIH grants guide at http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-09-015.html, and the NIH Office of Extramural Research (OER) webmaster contact was provided for access or linking issues. Overall, this FOA is best understood as a career-transition grant aimed at building the next generation of independent researchers who can lead innovative nanotechnology approaches to cancer problems, while tying those investigators into a larger NCI-supported network of centers, platforms, and training programs.
FAQs: Pathway to Independence Award in Cancer Nanotechnology Research (K99/R00) (RFA-CA-09-015)
What is this funding opportunity?
The Pathway to Independence Award in Cancer Nanotechnology Research (K99/R00) is a National Cancer Institute (NCI), NIH funding opportunity designed to help promising postdoctoral researchers transition more quickly from mentored training to stable, independent faculty-level research positions focused on cancer nanotechnology.
Who runs and sponsors the program?
The opportunity is sponsored by the National Cancer Institute (NCI), part of the National Institutes of Health (NIH).
What is the main goal of the K99/R00 in cancer nanotechnology?
The goal is to reduce the lag time between postdoctoral training and research independence by providing a two-phase award that supports a mentored postdoctoral period and then an independent period once the investigator secures an independent research position, specifically in the interdisciplinary area of cancer nanotechnology.
How does the K99/R00 two-phase structure work?
This FOA uses the NIH K99/R00 "Pathway to Independence" structure:
- K99 (mentored phase): Intended for advanced postdoctoral or equivalent candidates who benefit from structured supervision while developing a research niche, expanding technical skills, publishing, and preparing for independence.
- R00 (independent phase): Supports the same investigator after they obtain an independent research position (typically tenure-track or equivalent), helping them launch their own lab and independent research program earlier than might be possible through standard NIH research grants alone.
What research area is this FOA focused on?
The FOA is focused on cancer nanotechnology research, at the intersection of cancer research and nanoscale science and engineering, with the broader aim of accelerating nanotechnology-driven approaches to cancer prevention, detection, diagnosis, treatment, and control.
How does this FOA fit within NCI programs?
This award sits within NCI's broader Alliance for Nanotechnology in Cancer program (nano.cancer.gov), which is designed to accelerate nanotechnology-driven cancer solutions and build a strong pipeline of early-career investigators in the field.
What other Alliance for Nanotechnology in Cancer funding components are mentioned?
The FOA is described as complementing other Alliance components that support the broader ecosystem for the field, including:
- Centers for Cancer Nanotechnology Excellence (CCNEs, U54)
- Cancer Nanotechnology Platform Partnerships (CNPPs, U01)
- Cancer Nanotechnology Training Centers (CNTCs, R25)
What types of cancer research activities does this funding align with?
The initiative is aligned with NIH cancer-related activity areas spanning cause and prevention, detection and diagnosis, treatment, and cancer control.
What is the anticipated funding level for this initiative?
NCI indicated about $2 million in total costs committed for fiscal year 2010, and about $10 million projected over a five-year period for this initiative.
How many awards were expected?
The FOA anticipated a relatively selective set of awards, with an expectation of roughly 8 to 10 awards.
Is this a discretionary grant program?
Yes. The program is categorized as discretionary grant funding.
Is cost sharing or matching required?
No. The announcement states there is no cost sharing or matching requirement.
Which CFDA numbers are associated with this opportunity?
The opportunity references NIH cancer-related CFDA numbers: 93.393, 93.394, 93.395, and 93.399.
Who is eligible to apply (institution/organization types)?
Eligibility on the institutional side is described as broad and includes many organization types that can administer NIH grants, including:
- Public and private institutions of higher education
- Nonprofit organizations (including those with and without 501(c)(3) status, with distinctions noted in the source listing)
- For-profit organizations (including small businesses)
- City/township, county, and state governments
- Eligible federal agencies
- Regional organizations
- U.S. territories or possessions
The FOA text is identified as the authoritative source for any eligibility clarifications.
Who is the award primarily intended to support?
The award is intended to support promising postdoctoral researchers (or equivalent candidates) who are ready to transition from mentored training to independent, faculty-level research careers in cancer nanotechnology.
What kind of position is typically expected for the independent (R00) phase?
The R00 phase is meant to support the investigator after they secure an independent research position, typically a tenure-track or equivalent role, to launch an independent lab and research program.
When was this FOA posted, and what were the key dates?
The opportunity was posted on October 8, 2009. The original and current closing date was December 17, 2009. The archive date was January 17, 2010.
Is this opportunity currently open?
No. Based on the dates provided (closing date in 2009 and archive date in 2010), this is a historical announcement rather than a currently open competition.
What is the Funding Opportunity Number and official title?
The Funding Opportunity Number is RFA-CA-09-015, and the official title is Pathway to Independence Award in Cancer Nanotechnology Research (K99/R00).
Where can the original NIH announcement be found?
The full announcement was hosted through the NIH grants guide at: http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-09-015.html.
Who was listed as a contact for access or linking issues?
The NIH Office of Extramural Research (OER) webmaster contact was provided for access or linking issues.
What is the big-picture purpose of supporting K99/R00 awardees within this Alliance?
The FOA is intended to build and sustain a pipeline of early-career investigators who can form independent research programs in cancer nanotechnology and plug into a larger NCI-supported network of centers, collaborative platforms, and training programs within the Alliance for Nanotechnology in Cancer.
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