Opportunity Information: Apply for PA 14 312

  • The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Patient Safety in the Context of Perinatal, Neonatal, and Pediatric Care (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865 Child Health and Human Development Extramural Research.
  • This funding opportunity was created on Aug 6, 2014 and posted on Aug 6, 2014.
  • Applicants must submit their applications by Sep 7, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: City or township governments Independent school districts Private institutions of higher education County governments Special district governments Native American tribal organizations (other than Federally recognized tribal governments) Small businesses State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

Patient Safety in the Context of Perinatal, Neonatal, and Pediatric Care (R01) is a National Institutes of Health (NIH) discretionary grant opportunity (Funding Opportunity Number PA-14-312; CFDA 93.865) designed to support collaborative, research-driven projects focused on improving patient safety for newborns, infants, children, and perinatal patients. The program targets safety issues across typical hospital environments as well as high-acuity settings like neonatal and pediatric intensive care units, where care is complex and the risk of preventable harm can be higher. The central idea is to generate practical, evidence-based knowledge that helps health systems deliver safer, higher-quality care to mothers and children.

The scope of research encouraged by the FOA is broad and covers the full pathway from understanding harm to preventing it. Applicants are invited to study the epidemiology of medical errors, meaning research that quantifies how often different types of errors occur, under what circumstances they happen, and what kinds of outcomes they produce for patients. The announcement also emphasizes examining patient harm that results from these errors and identifying contributing factors across multiple levels. That includes individual-level factors (such as clinician workload, training, communication, decision-making under uncertainty, and human factors), system-level factors (like workflows, handoffs, medication management processes, electronic health record design, alarms and monitoring, staffing models, and coordination across departments), and institutional-level factors (including safety culture, leadership, policies, reporting systems, quality infrastructure, and accountability structures). In addition to descriptive and causal work, the FOA encourages intervention research that tests strategies to reduce or eliminate errors. These interventions can be aimed at clinicians, care teams, or families, or they can be broader system and organizational changes, such as redesigning care processes, implementing standardized protocols, improving communication and handoff tools, applying checklists, or using data-driven quality improvement and learning health system approaches.

This is an R01 mechanism, which typically supports substantial, hypothesis-driven or well-justified programmatic research that can produce generalizable findings. While the FOA text highlights collaboration, it is not restricted to a single discipline; rather, it is intended to bring together the kinds of expertise commonly needed for patient safety research in pediatric and perinatal care, such as clinical pediatrics and neonatology, obstetrics, nursing, pharmacy, health services research, implementation science, epidemiology, biostatistics, human factors engineering, informatics, and organizational science. The expected payoff is actionable evidence: results that can inform strategies, tools, and policies that measurably improve safety and reduce preventable harm in real clinical settings.

Eligibility is expansive and includes many types of organizations that might participate in or lead patient safety research. Eligible applicants include public and private institutions of higher education, nonprofits (including both 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (including small businesses), and a range of governmental entities such as state, county, city/township, special district governments, and independent school districts. Tribal governments and tribal organizations are eligible, including federally recognized tribal governments, and there is specific inclusion of institutions serving underrepresented populations such as HBCUs, Hispanic-serving institutions, AANAPISIs, Tribal Colleges and Universities, and Alaska Native and Native Hawaiian-serving institutions. Importantly, non-U.S. organizations and foreign institutions are also eligible to apply, and foreign components of U.S. organizations are allowed under NIH policy, which supports projects that may involve international collaboration or comparative learning across health systems when relevant.

From an administrative standpoint, this opportunity had no cost sharing or matching requirement. It was posted and created on August 6, 2014, with an original and final listed closing date of September 7, 2017, and it was archived on October 8, 2017. The full announcement was hosted through the NIH Grants Guide at http://grants.nih.gov/grants/guide/pa-files/PA-14-312.html, and NIH’s Office of Extramural Research provided technical contact support for access or linking issues via the OER webmaster email. Overall, the FOA reflects NIH’s interest in building a stronger evidence base for preventing errors and harm in perinatal, neonatal, and pediatric care, with the goal of translating research findings into safer, more reliable healthcare delivery for children and families.

Frequently Asked Questions (FAQs)

What is the name of this NIH grant opportunity?

The opportunity is titled Patient Safety in the Context of Perinatal, Neonatal, and Pediatric Care (R01).

What is the Funding Opportunity Number (FOA) for this program?

The Funding Opportunity Number is PA-14-312.

What CFDA number is associated with this grant?

The CFDA number listed is 93.865.

What type of grant mechanism is used?

This opportunity uses the NIH R01 mechanism, which typically supports substantial, research-driven projects intended to produce generalizable, evidence-based findings.

What is the main purpose of this FOA?

The goal is to support collaborative research that improves patient safety for perinatal, neonatal, and pediatric patients by generating practical, evidence-based knowledge that health systems can use to reduce preventable harm and improve care quality.

Which patient populations does this FOA focus on?

The FOA focuses on patient safety for newborns, infants, children, and perinatal patients, with an emphasis on improving safety for mothers and children in clinical care settings.

What care settings are included in the scope of this opportunity?

The scope includes safety issues in typical hospital environments as well as high-acuity settings where care is more complex, such as neonatal intensive care units (NICUs) and pediatric intensive care units (PICUs).

What kinds of research topics are encouraged?

The FOA encourages a broad range of patient safety research, including work that (1) measures and characterizes errors and harm, (2) studies contributing factors, and (3) tests interventions to reduce or eliminate errors and prevent harm in real clinical settings.

Does the FOA support research on the epidemiology of medical errors?

Yes. The FOA explicitly encourages research on the epidemiology of medical errors, including how frequently errors occur, under what circumstances they happen, and what outcomes they produce.

Does this opportunity include research on patient harm resulting from errors?

Yes. The announcement emphasizes examining patient harm that results from medical errors, along with identifying factors that contribute to those errors and harms.

What types of contributing factors can be studied?

The FOA highlights multi-level contributing factors, including:

  • Individual-level factors: clinician workload, training, communication, decision-making under uncertainty, and human factors.
  • System-level factors: workflows, handoffs, medication management, electronic health record design, alarms and monitoring, staffing models, and cross-department coordination.
  • Institutional-level factors: safety culture, leadership, policies, reporting systems, quality infrastructure, and accountability structures.

Does the FOA support intervention research?

Yes. The FOA encourages intervention research that tests strategies to reduce or eliminate errors and improve patient safety in perinatal, neonatal, and pediatric care.

What kinds of interventions are mentioned as examples?

Examples include interventions aimed at clinicians, care teams, families, and/or broader organizational systems, such as:

  • Redesigning care processes
  • Implementing standardized protocols
  • Improving communication and handoff tools
  • Applying checklists
  • Using data-driven quality improvement approaches
  • Using learning health system approaches

Is collaboration required or encouraged?

Collaboration is emphasized. The FOA is designed to support collaborative, research-driven projects and encourages bringing together the expertise often needed for patient safety research across pediatric and perinatal care.

What disciplines or areas of expertise are relevant to this FOA?

The FOA highlights that projects may involve expertise such as clinical pediatrics and neonatology, obstetrics, nursing, pharmacy, health services research, implementation science, epidemiology, biostatistics, human factors engineering, informatics, and organizational science.

Who is eligible to apply?

Eligibility is broad and includes:

  • Public and private institutions of higher education
  • Nonprofits (including 501(c)(3) and certain non-501(c)(3) entities)
  • For-profit organizations (including small businesses)
  • Governmental entities (state, county, city/township, special district governments, and independent school districts)
  • Tribal governments and tribal organizations (including federally recognized tribal governments)
  • Institutions serving underrepresented populations (including HBCUs, Hispanic-serving institutions, AANAPISIs, Tribal Colleges and Universities, and Alaska Native and Native Hawaiian-serving institutions)
  • Non-U.S. organizations and foreign institutions

Are foreign institutions allowed to apply?

Yes. Non-U.S. organizations and foreign institutions are eligible to apply, and foreign components of U.S. organizations are allowed under NIH policy.

Is cost sharing or matching required?

No. The opportunity states there is no cost sharing or matching requirement.

When was this opportunity posted and when did it close?

It was posted/created on August 6, 2014. The listed original and final closing date was September 7, 2017.

Is this FOA still active?

No. The opportunity was archived on October 8, 2017.

Where can the original FOA announcement be found?

The full announcement was hosted in the NIH Grants Guide at: http://grants.nih.gov/grants/guide/pa-files/PA-14-312.html

Who provides technical support for access or linking issues related to the NIH posting?

NIH’s Office of Extramural Research (OER) provided technical contact support for access or linking issues via the OER webmaster email referenced in the posting.

What is the intended impact of the research funded under this FOA?

The intended payoff is actionable, evidence-based results that inform strategies, tools, and policies to measurably improve safety and reduce preventable harm in real-world perinatal, neonatal, and pediatric care settings.

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