Opportunity Information: Apply for RFA AG 11 008

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Paul B. Beeson Clinical Scientist Development Award in Aging (K08)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.859 Biomedical Research and Research Training 93.866 Aging Research.
  • This funding opportunity was created on Aug 20, 2010 and posted on Aug 20, 2010.
  • Applicants must submit their applications by Nov 9, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $1,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) State governments Small businesses For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Special district governments Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) County governments Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The Paul B. Beeson Clinical Scientist Development Award in Aging (K08) is an NIH career development grant designed to help clinically trained faculty build the expertise and track record needed to become independent investigators in basic aging research. The focus is explicitly on basic, non-patient-oriented aging science, meaning the supported research and training are intended to strengthen foundational, mechanistic, or laboratory-based work rather than direct clinical studies involving patients. The award provides a structured, mentored period lasting three to five years, during which the recipient develops research skills, produces publishable findings, and positions themselves to compete for independent research funding. A key program feature is an annual meeting that brings awardees together with national mentors and peers, creating networking and collaboration opportunities that can help shape a long-term research career in aging.

This funding opportunity uses the NIH Research Career Development Award mechanism K08, which is commonly used to support mentored career development for clinically trained investigators who are transitioning toward research independence. The Beeson K08 is aimed at individuals already in strong research environments who will work under the guidance of a primary mentor and, where appropriate, additional mentors. The intention is that the mentored phase is not just a funding source but a deliberate career development period with clear training objectives and a pathway toward establishing an independent program in basic aging research. For clinically trained professionals whose interests are instead centered on patient-oriented research, the related Beeson K23 program is identified as the more appropriate fit (RFA AG 11 009), which signals a clear separation between basic aging research (K08) and patient-oriented biomedical research (K23) within the broader Beeson portfolio.

From a funding standpoint, the announcement anticipates a total FY 2011 program budget of about $1,000,000 and expects to make roughly 5 to 7 awards, depending on the number and quality of applications and the availability of funds. Applicants may request up to $200,000 per year in direct costs, but there are cumulative caps based on project duration: no more than $600,000 in direct costs total for a three-year award, $700,000 total for four years, and $800,000 total for five years. The notice also emphasizes that final award amounts can be significantly lower than the maximums, reinforcing that budgets should be reasonable and well-justified rather than automatically set at the ceiling. Although multiple NIH institutes are noted as supporting the program financially (including NIA, NIMH, and NINDS), awards are ultimately contingent on appropriated funds and a sufficient pool of highly meritorious applications.

Eligibility for applicant organizations is broad and includes many common NIH-eligible institution types across the nonprofit, academic, government, and certain for-profit sectors. Eligible applicants listed include public and private institutions of higher education, nonprofits with and without 501(c)(3) status, state and local governments (including counties, cities/townships, special districts, and independent school districts), federally recognized tribal governments and other tribal organizations, public housing authorities/Indian housing authorities, small businesses, and for-profit organizations other than small businesses. The opportunity also explicitly calls out additional eligible categories such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, faith-based and community-based organizations, regional organizations, and U.S. territories or possessions. No cost sharing or matching is required, which is typical of many NIH mechanisms and reduces institutional barriers to applying.

Administratively, this opportunity is identified as discretionary grant funding in the health category, with CFDA numbers tied to aging research and biomedical research and training (including 93.866 Aging Research and related NIH extramural programs). The funding opportunity number is RFA AG 11 008, and it was posted on August 20, 2010, with an original and current closing date of November 9, 2010, and an archive date of December 10, 2010. While those dates indicate this specific announcement cycle is historical, the summary still reflects how the Beeson K08 is structured: mentored career development support for clinically trained faculty committed to building a basic aging research program, with defined budget limits, an expectation of strong mentorship and institutional research environment, and a cohort-style annual meeting intended to strengthen national connections and professional development.

FAQs: Paul B. Beeson Clinical Scientist Development Award in Aging (K08) - RFA AG 11 008

What is the Paul B. Beeson Clinical Scientist Development Award in Aging (K08)?

The Paul B. Beeson Clinical Scientist Development Award in Aging (K08) is an NIH mentored career development grant that supports clinically trained faculty as they build the skills, experience, and publication record needed to become independent investigators in basic aging research.

What kind of research does this Beeson K08 support?

This program is explicitly focused on basic, non-patient-oriented aging science. It is intended to strengthen foundational, mechanistic, or laboratory-based aging research and training rather than clinical studies that directly involve patients.

Does this award support patient-oriented research?

No. The announcement emphasizes that the K08 is for basic, non-patient-oriented aging research. Clinically trained investigators whose work is patient-oriented are directed to the related Beeson K23 program (RFA AG 11 009) as the more appropriate mechanism.

What NIH grant mechanism is used for this opportunity?

This funding opportunity uses the NIH Research Career Development Award mechanism K08, which is commonly used to support mentored career development for clinically trained investigators transitioning toward research independence.

How long is the mentored career development period?

The award provides a structured mentored period lasting three to five years.

What is the purpose of the mentored phase?

The mentored phase is described as a deliberate career development period, not just a funding source. It is intended to include clear training objectives and a pathway toward establishing an independent program in basic aging research, with the expectation that recipients develop research skills and produce publishable findings.

What mentorship structure is expected?

Awardees are expected to work under the guidance of a primary mentor and, where appropriate, additional mentors. The program is aimed at individuals already in strong research environments.

Is there a cohort or networking component?

Yes. A key feature is an annual meeting that brings awardees together with national mentors and peers, creating opportunities for networking and collaboration that can support long-term career development in aging research.

How much funding is available per year?

Applicants may request up to $200,000 per year in direct costs.

Are there total direct cost caps based on the project period?

Yes. The cumulative direct cost caps depend on the length of the award: no more than $600,000 total for three years, $700,000 total for four years, and $800,000 total for five years.

Should applicants automatically request the maximum budget?

No. The notice emphasizes that final award amounts can be significantly lower than the maximums. Budgets are expected to be reasonable and well-justified rather than set at the ceiling by default.

How many awards were expected to be made under this announcement?

The announcement anticipated making roughly 5 to 7 awards, depending on the number and quality of applications and the availability of funds.

What was the anticipated total program budget for FY 2011?

The announcement anticipated a total FY 2011 program budget of about $1,000,000.

Which NIH institutes were noted as supporting the program?

Multiple NIH institutes were noted as supporting the program financially, including NIA, NIMH, and NINDS. Awards were contingent on appropriated funds and a sufficient pool of highly meritorious applications.

What types of organizations are eligible to apply?

Eligibility is broad and includes many NIH-eligible institution types across nonprofit, academic, government, and certain for-profit sectors. Listed eligible applicants include public and private institutions of higher education; nonprofits with and without 501(c)(3) status; state and local governments (including counties, cities/townships, special districts, and independent school districts); federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; small businesses; and for-profit organizations other than small businesses.

Are specific institution categories called out as eligible?

Yes. The opportunity explicitly calls out additional eligible categories such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, faith-based and community-based organizations, regional organizations, and U.S. territories or possessions.

Is cost sharing or matching required?

No. The announcement states that no cost sharing or matching is required.

What is the funding opportunity number?

The funding opportunity number is RFA AG 11 008.

What is the CFDA listing associated with this opportunity?

The announcement ties the opportunity to CFDA numbers for aging research and biomedical research and training, including 93.866 (Aging Research and related NIH extramural programs).

When was this opportunity posted and when did it close?

The announcement was posted on August 20, 2010. The original and current closing date was November 9, 2010, and the archive date was December 10, 2010.

Is this specific announcement cycle current?

No. Based on the posted, closing, and archive dates provided, this specific announcement cycle is historical. The summary still reflects the program structure described in the announcement (mentored career development support for clinically trained faculty pursuing basic aging research, with defined budget limits and strong mentorship expectations).

How is this Beeson K08 different from the Beeson K23?

The K08 described here is for basic, non-patient-oriented aging research, while the related Beeson K23 (RFA AG 11 009) is identified as the better fit for clinically trained professionals pursuing patient-oriented research. The announcement highlights this as a clear separation within the Beeson portfolio.

What category of funding is this?

The opportunity is identified as discretionary grant funding in the health category.

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