Opportunity Information: Apply for RFA AG 12 004

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Paul B. Beeson Patient Oriented Research Career Development Award in Aging (K23)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.866 Aging Research.
  • This funding opportunity was created on Oct 25, 2011 and posted on Aug 1, 2011.
  • Applicants must submit their applications by Oct 28, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $1,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: State governments Private institutions of higher education City or township governments Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Public and State controlled institutions of higher education Special district governments Native American tribal organizations (other than Federally recognized tribal governments) County governments Independent school districts.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:

The Paul B. Beeson Patient Oriented Research Career Development Award in Aging (K23) is an NIH career development grant designed to help early-career, clinically trained faculty members, most often physicians, build the skills and track record needed to become independent leaders in aging research. The program is jointly supported by the National Institute on Aging (NIA) and the National Institute of Neurological Disorders and Stroke (NINDS), with additional financial participation from the John A. Hartford Foundation and the American Federation for Aging Research. The central aim is to expand the pipeline of clinician-scientists who can translate observations from patient care into rigorous research and, over time, establish their own sustained research programs focused on aging and age-related conditions, including those relevant to neurology and the aging brain.

This opportunity uses the NIH K23 mechanism, which focuses on patient-oriented research and structured career development. In practical terms, the award is meant to provide protected time and resources for mentored research training while the investigator develops deeper methodological expertise, produces publishable findings, and positions themselves for future independent NIH funding. The emphasis on patient-oriented work signals that the supported research should directly involve human subjects or human-derived data and specimens in a way that is tightly connected to clinical questions in aging. The overall intent is not simply to fund a single project, but to invest in the development of a clinician-researcher who will continue contributing to the field long after the award period ends.

Administratively, the funding opportunity is identified as RFA-AG-12-004 and was offered under the NIH discretionary grant category, with a health-related funding activity focus. It is associated with CFDA numbers 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders) and 93.866 (Aging Research), reflecting the involvement of both NINDS and NIA and the broad scientific scope spanning aging and neurological aspects of aging. The announcement listed an estimated total funding level of about $1,000,000, with an award ceiling of $200,000. No cost sharing or matching was required, meaning applicants were not expected to contribute non-federal funds as a condition of receiving the award.

Eligibility to apply was broad at the institutional level and included many types of U.S.-based organizations, such as public and private institutions of higher education, nonprofits (including those with and without 501(c)(3) status, other than higher education institutions), small businesses, for-profit organizations other than small businesses, and multiple levels of government (state, county, city/township, special district, and independent school districts). It also explicitly included a range of mission-driven and community-serving organizations and institutions, such as Historically Black Colleges and Universities, Hispanic-serving institutions, Tribally Controlled Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations, along with U.S. territories or possessions and certain regional organizations. At the same time, the announcement clearly excluded non-U.S. entities: foreign institutions could not apply, non-domestic components of U.S. organizations were not eligible, and foreign components were not allowed under the NIH policy definition. This keeps the award focused on building the U.S. clinician-scientist workforce in aging research.

Key dates in the posted record show the opportunity was posted August 1, 2011, created October 25, 2011, and had an original closing date of October 27, 2011, with a current closing date of October 28, 2011. The archive date was November 28, 2011. These dates indicate this specific announcement cycle is historical, but the Beeson career development concept has been a recurring NIH effort over the years, so organizations or investigators interested in similar support would typically look for the most current Beeson or K23-related NIH funding announcements.

For applicants seeking more detail, the full announcement was made available through the NIH grants posting referenced in the additional information link (http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-12-004.html). The notice also provided NIH Office of Extramural Research (OER) webmaster contact information for technical issues accessing the announcement online.

Frequently Asked Questions (FAQs)

What is the Paul B. Beeson Patient Oriented Research Career Development Award in Aging (K23)?

The Paul B. Beeson Patient Oriented Research Career Development Award in Aging (K23) is an NIH career development grant that uses the K23 mechanism to support patient-oriented research and structured career development. Its purpose is to help early-career, clinically trained faculty members (most often physicians) build the skills, research experience, and publication record needed to become independent leaders in aging research.

What is the central goal of this award?

The central goal is to expand the pipeline of clinician-scientists who translate observations from patient care into rigorous research and, over time, establish sustained, independent research programs focused on aging and age-related conditions, including topics relevant to neurology and the aging brain.

Which NIH institutes and organizations support this program?

This program is jointly supported by the National Institute on Aging (NIA) and the National Institute of Neurological Disorders and Stroke (NINDS). It also has additional financial participation from the John A. Hartford Foundation and the American Federation for Aging Research.

What does it mean that this is a K23 mechanism?

The K23 mechanism is designed for career development in patient-oriented research. In practical terms, it is intended to provide protected time and resources for mentored research training while the investigator builds methodological expertise, produces publishable results, and becomes positioned for future independent NIH funding.

What kind of research does "patient-oriented research" refer to in this opportunity?

Based on the description provided, the supported research should directly involve human subjects or use human-derived data and specimens in a way that is closely tied to clinical questions in aging. The emphasis is on research connected to patient care and clinically grounded questions in aging and age-related conditions.

Is the award mainly funding a single research project or the investigator's career development?

The intent is not simply to fund a single project. The award is described as an investment in the development of a clinician-researcher who will continue contributing to aging research beyond the award period by building the foundation for an independent research program.

What is the funding opportunity announcement (FOA) number for this grant?

The funding opportunity is identified as RFA-AG-12-004.

What type of grant category and activity does this fall under?

It was offered under the NIH discretionary grant category, and it is described as having a health-related funding activity focus.

Which CFDA numbers are associated with this opportunity?

The opportunity is associated with CFDA 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders) and CFDA 93.866 (Aging Research). These reflect the involvement of NINDS and NIA and the scientific scope that spans aging and neurological aspects of aging.

How much funding was expected to be available in this announcement?

The announcement listed an estimated total funding level of about $1,000,000.

What was the award ceiling?

The award ceiling listed in the posted record was $200,000.

Is cost sharing or matching required?

No. The announcement stated that no cost sharing or matching was required, meaning applicants were not expected to contribute non-federal funds as a condition of receiving the award.

What types of organizations were eligible to apply?

Eligibility at the institutional level included many U.S.-based organizations, including:

  • Public and private institutions of higher education
  • Nonprofits (including those with and without 501(c)(3) status, other than higher education institutions)
  • Small businesses
  • For-profit organizations other than small businesses
  • State, county, city/township governments
  • Special district governments
  • Independent school districts
  • U.S. territories or possessions and certain regional organizations
  • Faith-based and community-based organizations

Were minority-serving and community-serving institutions included in eligibility?

Yes. The announcement explicitly included a range of mission-driven and community-serving organizations and institutions, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations.

Are foreign institutions eligible to apply?

No. The announcement excluded non-U.S. entities. Foreign institutions could not apply, non-domestic components of U.S. organizations were not eligible, and foreign components were not allowed under the NIH policy definition.

Why does the announcement exclude foreign institutions and foreign components?

The description states that this keeps the award focused on building the U.S. clinician-scientist workforce in aging research.

What areas of science does this award target?

The award targets aging research and age-related conditions, including areas relevant to neurology and the aging brain, reflecting the joint involvement of NIA and NINDS.

When was this opportunity posted and when did it close?

Key dates in the posted record indicate it was posted on August 1, 2011, created on October 25, 2011, and had an original closing date of October 27, 2011, with a current closing date of October 28, 2011. The archive date was November 28, 2011.

Is this specific announcement cycle still active?

No. The dates indicate this specific announcement cycle is historical and was archived. However, the Beeson career development concept is described as a recurring NIH effort over the years, so interested applicants would typically look for the most current Beeson or K23-related NIH funding announcements.

Where can applicants find the full text of the original announcement?

The full announcement was made available through the NIH grants posting referenced in the additional information link: http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-12-004.html

Who should be contacted for technical issues accessing the announcement online?

The notice provided NIH Office of Extramural Research (OER) webmaster contact information for technical issues accessing the announcement online.

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Previous opportunity: Paul B. Beeson Clinical Scientist Development Award in Aging (K08)

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