Opportunity Information: Apply for RFA DK 11 009
Apply for RFA DK 11 009
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Pediatric Centers of Excellence in Nephrology (P50)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on Jul 21, 2011 and posted on Jul 21, 2011.
- Applicants must submit their applications by Nov 3, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,400,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $750,000.00 in funding.
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education For profit organizations other than small businesses Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) County governments Small businesses City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Special district governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply.
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Opportunity Summary:
The Pediatric Centers of Excellence in Nephrology (P50) funding opportunity (RFA-DK-11-009) is a National Institutes of Health (NIH) grant announcement from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) designed to support comprehensive center-based research programs focused on kidney disease in infants, children, and adolescents. It supports both basic science and clinical research, with the overall goal of building strong, multidisciplinary pediatric nephrology research hubs that can generate new knowledge about disease mechanisms and move promising ideas toward real-world clinical impact.
A central priority of the program is to draw fresh scientific expertise into pediatric kidney research, particularly investigators who may not traditionally work in nephrology but bring useful tools, perspectives, or technologies. The FOA emphasizes multidisciplinary collaboration, encouraging teams that cut across fields to study the causes and biology of pediatric kidney diseases and disorders. Another stated emphasis is exploring new basic research directions that could reasonably translate into clinical research applications, reflecting an interest in making sure fundamental discoveries have a pathway toward improving diagnosis, prevention, and treatment.
The announcement also highlights the importance of Developmental Research (DR) and Pilot and Feasibility (PF) projects within the center. These smaller, more exploratory studies are intended to spark innovative approaches and generate preliminary data. A key expectation is that these projects will position investigators to submit strong, competitive, investigator-initiated R01 applications later, meaning the centers are not only meant to produce research findings but also to cultivate a pipeline of fundable, independent pediatric kidney disease research programs.
These Pediatric Centers of Excellence are described as complementary to the O'Brien Kidney and Urological Research Centers, indicating that the program is meant to fit into NIDDK's broader kidney research infrastructure rather than duplicate it. In practice, that means applicants should expect to justify how their center adds distinctive pediatric-focused value while aligning with national priorities in kidney and urologic research. NIDDK also provided a reference page listing currently supported centers through its center programs website.
From a funding and administrative standpoint, this is a discretionary grant program using the P50 center grant mechanism. The FOA projected an estimated total funding amount of $2,400,000 and anticipated making about 2 awards. The award ceiling was listed as $750,000, and there was no cost-sharing or matching requirement. The opportunity was posted on July 21, 2011, with an original and current closing date of November 3, 2011, and an archive date of December 4, 2011, meaning the announcement is no longer active but remains useful as a reference for similar future solicitations.
Eligibility is broad across U.S.-based organizations and governmental entities. Eligible applicants included public and private institutions of higher education, nonprofit organizations (including both 501(c)(3) and certain non-501(c)(3) nonprofits), for-profit organizations other than small businesses (with small businesses also listed as eligible), and a wide range of state, local, and tribal government entities. The FOA explicitly included several categories of institutions and organizations often highlighted in federal funding eligibility language, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribal Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, faith-based and community-based organizations, and U.S. territories or possessions. At the same time, it clearly stated that non-U.S. (foreign) institutions were not eligible to apply, and non-U.S. components of U.S. organizations were also not eligible.
For applicants who needed the full details, the FOA pointed to the NIH Grants Guide posting (RFA-DK-11-009) and provided NIH Office of Extramural Research (OER) webmaster contact information for technical access or linking issues. Overall, the opportunity was structured to build durable pediatric nephrology research centers that blend basic and clinical investigation, seed novel pilot work, and accelerate the development of future R01-level projects in pediatric kidney disease.
Frequently Asked Questions (FAQs): Pediatric Centers of Excellence in Nephrology (P50) - RFA-DK-11-009
What is the Pediatric Centers of Excellence in Nephrology (P50) funding opportunity?
This opportunity (RFA-DK-11-009) is an NIH grant announcement from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). It uses the P50 center grant mechanism to support comprehensive, center-based research programs focused on kidney disease in infants, children, and adolescents.
What is the main goal of this program?
The overall goal is to build strong, multidisciplinary pediatric nephrology research hubs that generate new knowledge about pediatric kidney disease mechanisms and move promising ideas toward real-world clinical impact.
What types of research does the program support?
The program supports both basic science and clinical research related to kidney disease in pediatric populations (infants, children, and adolescents). The announcement emphasizes research that improves understanding of disease causes and biology, with an eye toward translation into clinical applications.
Which patient populations are the focus of this funding opportunity?
The focus is kidney disease affecting infants, children, and adolescents (pediatric kidney disease and disorders).
Does the FOA emphasize multidisciplinary collaboration?
Yes. A stated priority is multidisciplinary collaboration across fields to study pediatric kidney diseases and disorders. The FOA encourages teams that cut across disciplines rather than staying within traditional nephrology-only approaches.
Does NIDDK want investigators from outside traditional nephrology to participate?
Yes. A central priority is drawing fresh scientific expertise into pediatric kidney research, including investigators who may not traditionally work in nephrology but bring valuable tools, perspectives, or technologies.
How does the FOA describe the balance between basic discovery and clinical impact?
The FOA highlights exploring new basic research directions that could reasonably translate into clinical research applications. In other words, fundamental discovery is encouraged, but with a pathway toward improving diagnosis, prevention, and treatment.
What are Developmental Research (DR) projects in this center program?
Developmental Research (DR) projects are smaller, exploratory studies within the center intended to spark innovative approaches and generate preliminary data that can support future, larger-scale research efforts.
What are Pilot and Feasibility (PF) projects?
Pilot and Feasibility (PF) projects are also smaller, exploratory projects designed to test new ideas and generate early evidence (preliminary data). They are intended to help investigators refine concepts and strengthen future applications.
What is a key expectation for DR and PF projects?
A key expectation is that DR and PF projects will position investigators to submit competitive, investigator-initiated R01 applications later. The centers are intended to help build a pipeline of independent, fundable research programs in pediatric kidney disease.
Is the program intended to develop future R01 applications?
Yes. Beyond producing research findings, the program is explicitly designed to cultivate investigators and projects that can mature into strong R01 submissions.
How do these Pediatric Centers of Excellence relate to the O'Brien Kidney and Urological Research Centers?
The FOA describes these Pediatric Centers of Excellence as complementary to the O'Brien Kidney and Urological Research Centers. This indicates the program is meant to fit into NIDDK's broader kidney research infrastructure rather than duplicate existing center efforts.
What does it mean that the centers are "complementary" to other NIDDK centers?
Based on the FOA language, applicants should be prepared to justify how their proposed center adds distinctive pediatric-focused value while aligning with national priorities in kidney and urologic research.
What grant mechanism is used for this opportunity?
This is a discretionary grant program using the NIH P50 center grant mechanism.
How much total funding was projected for this FOA?
The FOA projected an estimated total funding amount of $2,400,000.
How many awards did NIDDK anticipate making?
The FOA anticipated making about 2 awards.
What was the award ceiling?
The award ceiling listed in the announcement was $750,000.
Is cost sharing or matching required?
No. The FOA stated there was no cost-sharing or matching requirement.
When was the opportunity posted?
The opportunity was posted on July 21, 2011.
What were the closing dates for the FOA?
The original and current closing date was November 3, 2011.
Is this funding opportunity still active?
No. The archive date was December 4, 2011, meaning the announcement is no longer active. It may still be useful as a reference point for similar future solicitations.
Who is eligible to apply?
Eligibility was broad across U.S.-based organizations and governmental entities. Eligible applicants included public and private institutions of higher education, nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) nonprofits), for-profit organizations, small businesses, and various state, local, and tribal government entities.
Are minority-serving institutions and community-based organizations included in eligibility?
Yes. The FOA explicitly included categories commonly referenced in federal eligibility language, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribal Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, faith-based organizations, community-based organizations, and U.S. territories or possessions.
Are foreign (non-U.S.) institutions eligible to apply?
No. The FOA stated that non-U.S. (foreign) institutions were not eligible to apply.
Are non-U.S. components of U.S. organizations eligible?
No. The FOA stated that non-U.S. components of U.S. organizations were not eligible.
Where can applicants find the full official FOA details?
The FOA pointed applicants to the NIH Grants Guide posting for RFA-DK-11-009 for the complete program and application details.
Is there a reference for currently supported NIDDK centers?
Yes. NIDDK provided a reference page listing currently supported centers through its center programs website.
Who should be contacted for technical issues accessing the FOA information online?
The FOA provided NIH Office of Extramural Research (OER) webmaster contact information for technical access or linking issues.
What is the overall intended outcome of establishing these centers?
Based on the FOA description, the intent is to create durable pediatric nephrology research centers that blend basic and clinical investigation, seed novel pilot work through DR and PF projects, and accelerate development of future R01-level pediatric kidney disease research programs.
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