Opportunity Information: Apply for RFA EB 15 002
Apply for RFA EB 15 002
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Pediatric Research using Integrated Sensor Monitoring Systems (PRISMS) Sensor Development Projects for Asthma (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health.
- This funding opportunity was created on Mar 25, 2015 and posted on Mar 25, 2015.
- Applicants must submit their applications by Jun 1, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,500,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $350,000.00 in funding.
- The number of recipients for this funding is limited to 6 candidate(s).
- Eligible applicants include: City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education For profit organizations other than small businesses Native American tribal governments (Federally recognized) Small businesses Others (see text field entitled Additional Information on Eligibility for clarification) State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Private institutions of higher education County governments Special district governments Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The Pediatric Research using Integrated Sensor Monitoring Systems (PRISMS) Sensor Development Projects for Asthma (U01) opportunity, Funding Opportunity Number RFA-EB-15-002, is a National Institutes of Health (NIH) cooperative agreement solicitation focused on building better sensor technologies for pediatric asthma research. The core idea is to support projects that create or adapt wearable and non-wearable sensors capable of tracking, in real-world daily settings, the kinds of factors that can influence asthma in children. This includes sensors that measure environmental exposures (for example, air quality-related indicators), physiological signals, physical activity, and behavior, with the overall goal of producing new insights into the environmental determinants of asthma rather than relying only on clinic-based snapshots or self-reported data.
A defining feature of this FOA is that sensor development is not meant to happen in isolation. The sensors funded under RFA-EB-15-002 are expected to be interoperable and designed with a "plug and play" mindset so they can connect physically or wirelessly to a separate informatics platform being funded under a companion announcement (RFA-EB-15-003). That platform is intended to handle end-to-end data acquisition from the sensors, data integration across multiple streams, processing, visualization, and secure uploading of results. In addition, the program anticipates a data and software coordination and integration center funded through another companion FOA (RFA-EB-15-004). Together, these three coordinated funding announcements form the larger PRISMS Program, whose mission is to create integrated, sensor-based health monitoring systems that function as research tools for epidemiologic studies in pediatric asthma, with an explicit longer-term vision that the same approach could be extended to other chronic diseases affecting children.
Because this is a U01 cooperative agreement, NIH expects substantial scientific and programmatic involvement during the project period, with awardees collaborating closely with NIH and with the other PRISMS award teams to ensure the overall system works as an integrated whole. In practical terms, this means applicants need to think beyond an individual device and consider how their sensor will interface with the PRISMS informatics platform and how its data will ultimately move into the program-wide coordination center. The emphasis on natural environment monitoring also signals that devices should be realistic for pediatric use, capable of operating outside controlled laboratory conditions, and suitable for capturing meaningful, high-quality data during everyday life.
The opportunity was posted March 25, 2015, with an original and final closing date of June 1, 2015, and it was archived July 2, 2015. NIH anticipated making about 6 awards under this FOA, with an estimated total funding amount of $2,500,000 and an award ceiling of $350,000. There is no cost sharing or matching requirement listed. The activity aligns with CFDA 93.286, which centers on discovery and applied research for technological innovations to improve human health.
Eligibility is broad across U.S.-based organizations and government entities, reflecting the technical and translational nature of sensor development. Eligible applicants include state, county, city or township governments, special district governments, independent school districts, public housing authorities/Indian housing authorities, federally recognized and other tribal governments and tribal organizations, regional organizations, public and private institutions of higher education, public and state-controlled institutions of higher education, nonprofits with or without 501(c)(3) status (with the noted exclusions), and for-profit organizations other than small businesses, as well as small businesses. The FOA also explicitly includes a range of mission-driven and capacity-building institution types such as HBCUs, Hispanic-serving institutions, Tribally Controlled Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, and AANAPISIs, along with faith-based and community-based organizations and eligible federal agencies. Non-U.S. (foreign) institutions are not eligible to apply, and non-U.S. components of U.S. organizations are not eligible; however, foreign components, as defined by NIH policy, are allowed.
For applicants seeking the official details, NIH provided an announcement link (http://grants.nih.gov/grants/guide/rfa-files/RFA-EB-15-002.html) and routed access and technical issues to the NIH Office of Extramural Research (OER) webmaster contact. Overall, this FOA is best understood as the sensor-creation arm of a three-part, tightly coordinated program intended to modernize how pediatric asthma researchers measure real-world exposures and responses by making sensor data collection interoperable, scalable, and ready for integration into shared platforms and centralized coordination infrastructure.
Frequently Asked Questions (FAQs)
1) What is the PRISMS Sensor Development Projects for Asthma (U01) opportunity?
It is an NIH cooperative agreement funding opportunity focused on developing or adapting sensor technologies to support pediatric asthma research in real-world, everyday settings. The opportunity is titled "Pediatric Research using Integrated Sensor Monitoring Systems (PRISMS) Sensor Development Projects for Asthma (U01)."
2) What is the Funding Opportunity Number for this announcement?
The Funding Opportunity Number (FOA) is RFA-EB-15-002.
3) What is the main purpose of this FOA?
The main purpose is to support projects that create or adapt wearable and non-wearable sensors that can track factors influencing asthma in children during daily life. The goal is to enable new insights into environmental determinants of asthma using objective monitoring rather than relying only on clinic visits or self-reported information.
4) What kinds of sensors or measurements are expected to be supported?
The FOA emphasizes sensors capable of tracking real-world factors relevant to pediatric asthma, including environmental exposures (such as air quality-related indicators), physiological signals, physical activity, and behavior.
5) Why does the FOA emphasize real-world (natural environment) monitoring?
The program is designed to move beyond controlled laboratory conditions and clinic-based snapshots by capturing meaningful, high-quality data during everyday life. This emphasis implies devices should be realistic for pediatric use and able to operate effectively outside controlled settings.
6) Is this purely a sensor-development program, or is it part of a larger system?
It is the sensor-creation arm of a larger three-part PRISMS Program. The FOA expects sensors to work as part of an integrated monitoring system that includes an informatics platform and a coordination/integration center funded through companion announcements.
7) What does "interoperable" and "plug and play" mean in the context of this FOA?
It means the sensor technologies should be designed so they can connect (physically or wirelessly) to a separate PRISMS informatics platform, supporting straightforward integration across multiple sensor data streams within the overall PRISMS system.
8) What companion FOAs are referenced, and how do they relate to this FOA?
This FOA (RFA-EB-15-002) is intended to work with a companion informatics platform announcement (RFA-EB-15-003) and a data/software coordination and integration center announcement (RFA-EB-15-004). Together, these coordinated FOAs form the PRISMS Program.
9) What is the role of the PRISMS informatics platform mentioned in the announcement?
The informatics platform (funded separately under RFA-EB-15-003) is intended to support end-to-end data acquisition from sensors, data integration across multiple streams, processing, visualization, and secure uploading of results.
10) What is the purpose of the data and software coordination and integration center?
The program anticipates a center funded under RFA-EB-15-004 that will provide program-wide data and software coordination and integration, supporting the broader PRISMS infrastructure.
11) What does it mean that this award mechanism is a U01 cooperative agreement?
A U01 cooperative agreement means NIH expects substantial scientific and programmatic involvement during the project period. Awardees are expected to collaborate closely with NIH and with other PRISMS award teams to ensure the overall system functions as an integrated whole.
12) What does the cooperative nature of the program imply for applicants?
Applicants are expected to think beyond a standalone device and consider how their sensor will interface with the PRISMS informatics platform and how sensor data will move into the program-wide coordination center, collaborating as part of an integrated program.
13) How many awards did NIH anticipate making under this FOA?
NIH anticipated making about 6 awards under RFA-EB-15-002.
14) What was the estimated total funding amount for this FOA?
The estimated total funding amount was $2,500,000.
15) Was there an award ceiling?
Yes. The award ceiling listed was $350,000.
16) Is cost sharing or matching required?
No cost sharing or matching requirement is listed for this FOA.
17) When was the opportunity posted, and what was the closing date?
The opportunity was posted on March 25, 2015. The original and final closing date was June 1, 2015.
18) Is this funding opportunity still open?
No. The FOA was archived on July 2, 2015, and the final closing date was June 1, 2015.
19) What CFDA number is associated with this opportunity, and what does it generally represent?
The activity aligns with CFDA 93.286, which centers on discovery and applied research for technological innovations to improve human health.
20) Who is eligible to apply?
Eligibility is broad across U.S.-based organizations and government entities. Eligible applicants include various levels of government (state, county, city or township), special district governments, independent school districts, public housing authorities/Indian housing authorities, tribal governments and tribal organizations, regional organizations, public and private institutions of higher education (including public and state-controlled institutions), nonprofits (with or without 501(c)(3) status, with noted exclusions), for-profit organizations (including small businesses, and for-profits other than small businesses), faith-based and community-based organizations, and eligible federal agencies.
21) Are mission-driven institution types specifically included?
Yes. The FOA explicitly includes HBCUs, Hispanic-serving institutions, Tribally Controlled Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, and AANAPISIs.
22) Are non-U.S. (foreign) institutions eligible to apply?
No. Non-U.S. (foreign) institutions are not eligible to apply.
23) Are non-U.S. components of U.S. organizations eligible?
No. Non-U.S. components of U.S. organizations are not eligible.
24) Are foreign components allowed at all under this FOA?
Yes. Foreign components, as defined by NIH policy, are allowed.
25) What is the long-term vision of the PRISMS Program beyond pediatric asthma?
While the immediate focus is pediatric asthma, the program states an explicit longer-term vision that the integrated, sensor-based monitoring approach could be extended to other chronic diseases affecting children.
26) Where can applicants find the official FOA details?
The official announcement link provided is http://grants.nih.gov/grants/guide/rfa-files/RFA-EB-15-002.html
27) Where were applicants directed for access or technical issues?
NIH routed access and technical issues to the NIH Office of Extramural Research (OER) webmaster contact.
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