Opportunity Information: Apply for RFA HD 10 002
Apply for RFA HD 10 002
- The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Pelvic Floor Disorders Network Clinical Sites (U10)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on Apr 9, 2010 and posted on Apr 9, 2010.
- Applicants must submit their applications by Jul 30, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $3,200,000.00 to eligible and selected applicants.
- Eligible applicants include: City or township governments County governments Special district governments For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Native American tribal governments (Federally recognized) State governments Others (see text field entitled Additional Information on Eligibility for clarification) Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Private institutions of higher education Small businesses.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Pelvic Floor Disorders Network Clinical Sites (U10) opportunity (Funding Opportunity Number RFA-HD-10-002) is a National Institutes of Health cooperative agreement run by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) in partnership with the Office of Research on Womens Health (ORWH). It supports institutions that are willing to serve as clinical sites in an ongoing, multi-center clinical research program focused on pelvic floor disorders in women. The overall aim is to build and sustain a coordinated network that can rigorously study the clinical and broader health impacts of these conditions, generate high-quality evidence about what works (and for whom), and translate that evidence into better care and reduced burden for women and their families.
For this program, pelvic floor disorders are defined broadly and include urinary incontinence, fecal incontinence, pelvic organ prolapse, and related sensory and emptying problems involving the lower urinary tract and gastrointestinal tract. The FOA emphasizes not only the medical and surgical dimensions of these disorders, but also the real-world factors that shape patient outcomes. That includes evaluating surgical and non-surgical treatments, pharmacologic therapies, and prevention approaches, as well as studying social, behavioral, and other contributors that influence symptoms, treatment choices, adherence, and quality of life. A notable theme is the push for innovative solutions to persistent clinical challenges, with an explicit intent to reduce the overall burden these disorders create for women and their families.
The award uses the NIH Cooperative Clinical Research (U10) mechanism, which means funded sites are expected to work closely with NIH program staff and other network partners rather than operating as fully independent investigator-initiated projects. In practice, a U10 network structure typically supports standardized protocols, shared data elements, coordinated recruitment and follow-up, and collaborative governance across multiple centers so the network can run large, well-controlled studies and produce results that are generalizable across different populations and care settings. This FOA is also described as running in parallel with a companion announcement of the same scientific scope that uses a different cooperative mechanism (U01; RFA-HD-10-024), reflecting a broader network model with distinct roles for different types of participating components.
NICHD and ORWH anticipated committing about $3.2 million in total costs (direct plus facilities and administrative costs) in fiscal year 2011, with the expectation of funding approximately 7 to 9 awards for new and/or competing continuation clinical site grants. The opportunity falls under the Health category (CFDA 93.865, Child Health and Human Development Extramural Research), does not require cost sharing or matching, and was posted April 9, 2010, with an application closing date of July 30, 2010 (archived August 30, 2010).
Eligibility is broad and includes many types of U.S.-based organizations and governmental entities. Eligible applicants include public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) organizations), for-profit organizations (other than small businesses are explicitly listed, and small businesses are also eligible), and multiple levels of government (state, county, city/township, special district), as well as independent school districts and public housing authorities/Indian housing authorities. The FOA also highlights eligibility for a range of mission-focused and community-serving entities such as faith-based or community-based organizations, historically black colleges and universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian serving institutions, federally recognized and other tribal governments/organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions.
In short, this FOA sought to expand or sustain a national, cooperative clinical research network by funding multiple clinical sites capable of carrying out coordinated studies on pelvic floor disorders in women, spanning treatment effectiveness, outcomes, contributing factors, and prevention, with a strong emphasis on innovation and measurable reductions in patient and family burden.
Frequently Asked Questions (FAQs)
What is the Pelvic Floor Disorders Network Clinical Sites (U10) funding opportunity?
It is a National Institutes of Health (NIH) cooperative agreement opportunity to support institutions that will serve as clinical sites in an ongoing, multi-center clinical research program focused on pelvic floor disorders in women. The specific Funding Opportunity Number is RFA-HD-10-002.
Which NIH institute leads this opportunity, and who are the partners?
The program is run by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) in partnership with the Office of Research on Womens Health (ORWH).
What is the overall purpose of funding clinical sites through this FOA?
The goal is to build and sustain a coordinated national network that can rigorously study pelvic floor disorders in women, generate high-quality evidence about what works (and for whom), and translate that evidence into better care and reduced burden for women and their families.
What conditions are considered "pelvic floor disorders" under this program?
The definition is broad and includes urinary incontinence, fecal incontinence, pelvic organ prolapse, and related sensory and emptying problems involving the lower urinary tract and gastrointestinal tract.
Does the FOA focus only on medical and surgical issues?
No. In addition to medical and surgical dimensions, the FOA emphasizes real-world factors that shape outcomes, including social and behavioral contributors that influence symptoms, treatment choices, adherence, and quality of life.
What types of interventions and approaches are within the scope of this network?
The FOA highlights evaluating surgical and non-surgical treatments, pharmacologic therapies, and prevention approaches, as well as studying factors that influence patient outcomes and experience.
Is innovation a priority in this funding opportunity?
Yes. A notable theme is the push for innovative solutions to persistent clinical challenges, with an explicit intent to reduce the overall burden these disorders create for women and their families.
What does it mean that this is a U10 cooperative agreement?
A U10 is an NIH Cooperative Clinical Research mechanism. Funded clinical sites are expected to work closely with NIH program staff and other network partners, rather than operating as fully independent investigator-initiated projects.
How does a U10 network typically operate in practice?
The FOA describes a multi-center structure that typically includes standardized protocols, shared data elements, coordinated recruitment and follow-up, and collaborative governance across participating centers, supporting large, well-controlled studies with broadly generalizable results.
Is there a related or companion funding announcement?
Yes. This FOA is described as running in parallel with a companion announcement of the same scientific scope that uses a different cooperative mechanism (U01; RFA-HD-10-024), reflecting a broader network model with distinct roles for different participating components.
How much funding did NIH anticipate for this program, and how many awards were expected?
NICHD and ORWH anticipated committing about $3.2 million in total costs in fiscal year 2011, with the expectation of funding approximately 7 to 9 awards for new and/or competing continuation clinical site grants.
What does "total costs" mean in the context of this FOA?
Total costs are described as including both direct costs and facilities and administrative (F&A) costs.
What is the CFDA number and category for this opportunity?
The opportunity falls under the Health category and is associated with CFDA 93.865 (Child Health and Human Development Extramural Research).
Is cost sharing or matching required?
No. The FOA states that cost sharing or matching is not required.
When was this funding opportunity posted, and what were the key dates?
It was posted April 9, 2010. The application closing date was July 30, 2010. The opportunity is noted as archived on August 30, 2010.
What types of organizations were eligible to apply?
Eligibility is broad and includes many U.S.-based organizations and governmental entities, including public and private institutions of higher education; nonprofits (including 501(c)(3) and certain non-501(c)(3) organizations); and for-profit organizations (with both small businesses and other than small businesses listed as eligible).
Are government entities eligible applicants?
Yes. Eligible applicants include multiple levels of government such as state governments, county governments, city/township governments, and special district governments, as well as independent school districts and public housing authorities/Indian housing authorities.
Are community-based or faith-based organizations eligible?
Yes. The FOA specifically highlights eligibility for faith-based or community-based organizations among the types of entities that may apply.
Are minority-serving and tribally affiliated institutions included in the eligibility list?
Yes. The FOA highlights historically black colleges and universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian serving institutions, and federally recognized and other tribal governments/organizations.
Are U.S. territories or possessions eligible?
Yes. The eligibility list includes U.S. territories or possessions.
What kind of role is NIH funding through this FOA: independent projects or network clinical sites?
The FOA is aimed at funding clinical sites that participate in a coordinated, multi-center network with shared protocols and collaborative governance, rather than fully independent investigator-initiated projects.
What is the main population focus of the research network?
The network is focused on pelvic floor disorders in women, including clinical and broader health impacts and the burden on women and their families.
What is the expected impact of the network's research?
The stated intent is to produce rigorous evidence that can be translated into improved care and measurable reductions in burden for women and their families.
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Applicants who have applied for this opportunity (RFA HD 10 002) also looked into and applied for these:
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| Child Health Research Career Development Award (CHRCDA) Program K12 Apply for RFA HD 10 007 Funding Number: RFA HD 10 007 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $400,000 |
| International Extramural Associates Research Development Awards (IEARDA) G11 Apply for PAR 10 172 Funding Number: PAR 10 172 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Advanced Tools and Technologies for Deep Brain Stimulation (STTR R41/R42) Apply for PA 10 175 Funding Number: PA 10 175 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Advanced Tools and Technologies for Deep Brain Stimulation (SBIR R43/R44) Apply for PA 10 176 Funding Number: PA 10 176 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Predoctoral Fellows in PharmD/PhD Programs (F31) Apply for PA 10 178 Funding Number: PA 10 178 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Postdoctoral Research Training in Pediatric Clinical and Developmental Pharmacology (T32) Apply for RFA HD 10 005 Funding Number: RFA HD 10 005 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Vulvodynia Systematic Epidemiologic, Etiologic or Therapeutic Studies (R01) Apply for PAR 10 190 Funding Number: PAR 10 190 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Vulvodynia Systematic Epidemiologic, Etiologic or Therapeutic Studies (R21) Apply for PAR 10 192 Funding Number: PAR 10 192 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Vulvodynia Systematic Epidemiologic, Etiologic or Therapeutic Studies (R03) Apply for PAR 10 191 Funding Number: PAR 10 191 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Natural History of Disorders Identifiable by Newborn Screening (R01) Apply for RFA HD 10 019 Funding Number: RFA HD 10 019 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $1,000,000 |
| Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Predoctoral Training Program in Systems Biology of Developmental Biology and Birth Defects(T32) Apply for PAR 10 193 Funding Number: PAR 10 193 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Predoctoral and Postdoctoral Training Program in Reproductive, Obstetric, Perinatal and Pediatric Epidemiology and Pharmacoepidemiology (T32) Apply for PAR 10 194 Funding Number: PAR 10 194 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Postdoctoral Research Training for Obstetricians and Gynecologists (T32) Apply for PAR 10 203 Funding Number: PAR 10 203 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Biophysical and Biomechanical Aspects of Embryonic Development (R21) Apply for PAR 10 222 Funding Number: PAR 10 222 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $200,000 |
| Biophysical and Biomechanical Aspects of Embryonic Development (R01) Apply for PAR 10 221 Funding Number: PAR 10 221 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Safe and Effective Instruments and Devices for Use in the Neonatal Intensive Care Units (SBIR R43) Apply for RFA HD 10 012 Funding Number: RFA HD 10 012 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $225,000 |
| Safe and Effective Instruments and Devices for Use in the Neonatal Intensive Care Units (STTR R41) Apply for RFA HD 10 013 Funding Number: RFA HD 10 013 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $225,000 |
| Innovative Therapies and Tools for Screenable Disorders in Newborns (R03) Apply for PAR 10 231 Funding Number: PAR 10 231 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
| Developmental Mechanisms of Human Structural Birth Defects (P01) Apply for RFA HD 10 006 Funding Number: RFA HD 10 006 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: $900,000 |
| NICHD Program Project Grant (P01) Apply for PAR 10 245 Funding Number: PAR 10 245 Agency: National Institutes of Health Category: Health Income Security and Social Services Funding Amount: Case Dependent |
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