Opportunity Information: Apply for PA 14 072

  • The National Institutes of Health in the education environment food and nutrition health income security and social services sector is offering a public funding opportunity titled "PHS 2014 02 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR R41/R42" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.121 Oral Diseases and Disorders Research 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.213 Research and Training in Complementary and Integrative Health 93.233 National Center on Sleep Disorders Research 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.307 Minority Health and Health Disparities Research 93.350 National Center for Advancing Translational Sciences 93.351 Research Infrastructure Programs 93.361 Nursing Research 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.399 Cancer Control 93.837 Cardiovascular Diseases Research 93.838 Lung Diseases Research 93.839 Blood Diseases and Resources Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.855 Allergy and Infectious Diseases Research 93.856 Microbiology and Infectious Diseases Research 93.859 Biomedical Research and Research Training 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research 93.867 Vision Research 93.879 Medical Library Assistance.
  • This funding opportunity was created on Dec 17, 2014 and posted on Jan 17, 2014.
  • Applicants must submit their applications by May 7, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Small businesses.
  • Other Eligible Applicants include the following Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.
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Opportunity Summary:

PHS 2014 02 (PA-14-072) is an NIH omnibus funding opportunity for the Small Business Technology Transfer (STTR) program, using the parent grant mechanisms R41 (Phase I) and R42 (Phase II). In practical terms, it is a broad, standing invitation for eligible U.S. small business concerns to propose early stage research and development projects that have clear commercial potential and that also advance the research and development missions of participating NIH components. The solicitation is described as an omnibus because it spans many NIH Institutes and Centers and a wide range of biomedical, behavioral, clinical, and health-related technology areas, with applicants expected to align their proposals to NIH-relevant topics referenced in the annual PHS 2014-2 SBIR/STTR Program Descriptions and Research Topics document.

The core purpose of this STTR FOA is to support projects where a small business is formally partnered with a U.S. research institution, reflecting the STTR program’s emphasis on technology transfer and collaboration. While the provided excerpt does not list the specific STTR allocation rules, the STTR framework generally requires meaningful work share and a clear plan for moving an innovation from the research setting toward a product, process, or service that can ultimately be commercialized. Projects can range from proof-of-concept studies (Phase I) to more advanced development, validation, and prototyping (Phase II), depending on the maturity of the technology and the goals proposed. The overarching expectation is that the proposed work is not only scientifically sound but also positioned to translate into real-world impact and a viable commercialization pathway.

The opportunity is categorized as a discretionary grant program and falls under multiple activity categories including education, environment, food and nutrition, health, and income security and social services, reflecting the breadth of NIH’s interests and the wide applicability of health technologies. The FOA is linked to a large set of CFDA program areas, signaling the range of NIH missions that can be addressed. These include, among others, environmental health (93.113), oral health (93.121), human genome research (93.172), deafness and communication disorders (93.173), complementary and integrative health (93.213), sleep disorders (93.233), mental health (93.242), alcohol and substance use research (93.273, 93.279), technological innovations to improve human health (93.286), minority health and health disparities (93.307), translational sciences (93.350), research infrastructure (93.351), nursing research (93.361), and an extensive set of cancer-related programs (93.393 through 93.399). It also covers major disease and organ-system research areas such as cardiovascular, lung, and blood diseases (93.837-93.839), arthritis and skin diseases (93.846), diabetes and digestive and kidney diseases (93.847), neuroscience and neurological disorders (93.853), allergy and infectious diseases and microbiology (93.855-93.856), broad biomedical research and training (93.859), child health and human development (93.865), aging (93.866), vision research (93.867), and medical library assistance (93.879). The takeaway is that applicants are not confined to a narrow topic area; instead, they should identify the NIH awarding component whose mission best fits their technology and shape the application to match the relevant topic priorities.

Eligibility is limited to U.S. small business concerns. Foreign entities are explicitly not eligible to apply, and non-U.S. components of U.S. organizations are also not eligible to apply. However, the FOA notes that foreign components, as defined by the NIH Grants Policy Statement, may be allowed in some circumstances, which typically means discrete project elements could potentially be conducted abroad if well justified and consistent with NIH policy, even though the applicant organization itself must be U.S.-based and meet small business requirements. The FOA also states there is no cost sharing or matching requirement, which is important for small businesses because it reduces the need to bring additional non-federal funds to meet a mandatory match.

From an applicant’s perspective, this parent STTR FOA functions as a main entry point for submitting investigator-initiated or topic-aligned STTR proposals to NIH during the active solicitation window. The key expectation is that the small business brings the commercialization drive and product-development focus, while the partnering research institution contributes complementary scientific capabilities, facilities, and expertise to strengthen the R&D plan. Applicants are directed to consult the PHS 2014-2 SBIR/STTR Program Descriptions and Research Topics for NIH to identify suitable topics and participating NIH components, which helps ensure the application is responsive to NIH priorities and routed appropriately for review and potential funding.

Important administrative details in the source data include a posted date of January 17, 2014, with an original closing date listed as January 7, 2015, and a current closing date of May 7, 2015, after which the opportunity was archived on June 6, 2015. The listing provides an additional information link to the NIH Grants Guide page for PA-14-072. For access or technical issues, the contact provided is the NIH Office of Extramural Research (OER) Webmaster (FBOWebmaster@OD.NIH.GOV), specifically for difficulties accessing or linking to the full announcement.

Overall, PA-14-072 is best understood as a broad NIH STTR grant solicitation designed to help U.S. small businesses move health-related innovations from the lab toward commercialization through a formal collaboration with a research institution, with topics spanning virtually the full range of NIH biomedical and health missions and with no required cost sharing.

FAQs: NIH STTR Omnibus FOA PHS 2014-02 (PA-14-072)

What is PHS 2014-02 (PA-14-072)?

PHS 2014-02 (PA-14-072) is an NIH omnibus funding opportunity announcement (FOA) for the Small Business Technology Transfer (STTR) program. It serves as a broad, standing invitation for eligible U.S. small business concerns to propose early-stage research and development projects that align with NIH missions and show clear commercial potential.

Why is this FOA described as an "omnibus" opportunity?

It is described as an omnibus solicitation because it spans many NIH Institutes and Centers and covers a wide range of biomedical, behavioral, clinical, and health-related technology areas. Applicants are expected to align their proposal to NIH-relevant topics referenced in the annual PHS 2014-2 SBIR/STTR Program Descriptions and Research Topics document.

What grant mechanisms (activity codes) are used under this opportunity?

This STTR parent FOA uses NIH parent grant mechanisms R41 for Phase I and R42 for Phase II.

What types of projects does this STTR FOA support?

The FOA supports early-stage research and development projects that are scientifically sound, advance the research and development missions of participating NIH components, and have a viable pathway toward commercialization. Projects may range from proof-of-concept studies (Phase I) to more advanced development, validation, and prototyping (Phase II), depending on the maturity of the technology and proposed goals.

What is the core purpose of the STTR program in this FOA?

The core purpose is to support projects where a small business is formally partnered with a U.S. research institution, reflecting STTR's emphasis on collaboration and technology transfer. The small business is expected to bring commercialization and product-development focus, while the research institution contributes complementary scientific capabilities, facilities, and expertise.

Who is eligible to apply?

Eligibility is limited to U.S. small business concerns. Foreign entities are explicitly not eligible to apply, and non-U.S. components of U.S. organizations are also not eligible to apply.

Are foreign components allowed as part of a project?

The FOA notes that foreign components (as defined by the NIH Grants Policy Statement) may be allowed in some circumstances. This generally means discrete project elements could potentially be conducted abroad if appropriately justified and consistent with NIH policy, even though the applicant organization itself must be U.S.-based and meet small business requirements.

Is cost sharing or matching required?

No. The FOA states there is no cost sharing or matching requirement.

What topic areas can be funded under this opportunity?

The topic scope is broad and can span many NIH mission areas, including biomedical, behavioral, clinical, and health-related technologies. The FOA is linked to many CFDA program areas, signaling that applicants are not confined to a narrow topic area and should instead identify the NIH awarding component whose mission best fits their technology.

How do applicants determine which NIH component and topics are a good fit?

Applicants are directed to consult the PHS 2014-2 SBIR/STTR Program Descriptions and Research Topics document to identify suitable topics and participating NIH components. Aligning to the relevant topic priorities helps ensure the application is responsive to NIH interests and routed appropriately for review and potential funding.

What NIH mission areas are referenced by the CFDA program list in the FOA?

The FOA references a wide set of CFDA program areas, including (among others) environmental health (93.113), oral health (93.121), human genome research (93.172), deafness and communication disorders (93.173), complementary and integrative health (93.213), sleep disorders (93.233), mental health (93.242), alcohol and substance use research (93.273, 93.279), technological innovations to improve human health (93.286), minority health and health disparities (93.307), translational sciences (93.350), research infrastructure (93.351), nursing research (93.361), cancer-related programs (93.393 through 93.399), cardiovascular/lung/blood diseases (93.837-93.839), arthritis and skin diseases (93.846), diabetes/digestive/kidney diseases (93.847), neuroscience and neurological disorders (93.853), allergy/infectious diseases/microbiology (93.855-93.856), broad biomedical research and training (93.859), child health and human development (93.865), aging (93.866), vision research (93.867), and medical library assistance (93.879).

What funding categories is this opportunity associated with?

The opportunity is categorized as a discretionary grant program and is associated with multiple activity categories including education, environment, food and nutrition, health, and income security and social services, reflecting the breadth of NIH interests and the wide applicability of health technologies.

What is the practical role of this parent STTR FOA for applicants?

From an applicant perspective, this parent STTR FOA functions as a main entry point for submitting investigator-initiated or topic-aligned STTR proposals to NIH during the active solicitation window, provided the work aligns with NIH-relevant topics and participating components.

What are the key dates listed for this opportunity?

The source data lists a posted date of January 17, 2014. The original closing date is listed as January 7, 2015, and the current closing date is May 7, 2015. The opportunity was archived on June 6, 2015.

Where can applicants find the official full announcement?

The listing provides an additional information link to the NIH Grants Guide page for PA-14-072.

Who should be contacted for access or technical issues with the announcement link?

For difficulties accessing or linking to the full announcement, the contact provided is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

What is the overarching expectation for proposed work under PA-14-072?

The overarching expectation is that the proposed work is scientifically sound, advances the R&D mission of the relevant NIH component, and is positioned to translate into real-world impact through a viable commercialization pathway, supported by a formal small business and research institution collaboration.

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Funding Number: PA 14 149
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Funding Number: RFA HG 14 005
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Funding Number: RFA OD 14 005
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Funding Number: PAR 14 201
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Funding Number: PA 15 034
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Funding Number: RFA ES 15 004
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Funding Number: PA 15 083
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