Opportunity Information: Apply for PAR 15 161
Apply for PAR 15 161
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Pilot and Feasibility Clinical Research Grants in Kidney Diseases (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on Mar 27, 2015 and posted on Mar 27, 2015.
- Applicants must submit their applications by May 7, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: State governments Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) City or township governments For profit organizations other than small businesses Special district governments Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public and State controlled institutions of higher education Independent school districts Private institutions of higher education County governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Pilot and Feasibility Clinical Research Grants in Kidney Diseases (R21) opportunity (Funding Opportunity Number PAR 15-161) is a National Institutes of Health (NIH) discretionary grant program designed to support early-stage, small-scale clinical and translational research projects focused on kidney diseases. It uses the NIH Exploratory/Developmental Research Grant mechanism (R21), which is typically meant for projects that are innovative, high-impact, and not yet ready for a large, definitive study. The main goal is to help researchers generate preliminary clinical evidence, refine study methods, test feasibility, or gather early signals of efficacy that can justify and shape a later, full-scale clinical study.
This FOA specifically encourages pilot and feasibility work across a broad range of human-focused research approaches in kidney disease, including clinical and translational studies, epidemiological investigations, and clinical trials. In practical terms, that means projects might involve testing a new diagnostic strategy in a limited cohort, evaluating the practicality of recruiting and retaining a particular patient population, collecting early data on a preventive or therapeutic intervention, or running a smaller randomized study to estimate effect sizes and optimize protocols. NIH emphasizes that the questions being addressed should be clinically meaningful and translational, with the potential to improve patient care, influence clinical practice, or have substantial public health relevance if later validated at scale.
A key feature of this program is its role as a stepping-stone: NIH anticipates that some successful R21-supported projects will evolve into larger, more definitive efforts, such as full-scale epidemiological studies, expanded diagnostic validation studies, or randomized clinical trials that test approaches to diagnosis, prevention, or treatment of kidney diseases. In other words, the R21 funding is intended to reduce uncertainty early on by supporting the kind of targeted, proof-of-concept clinical research that can de-risk a bigger, more expensive follow-up study.
From an administrative and eligibility standpoint, this is a grant (not a contract) and it does not require cost sharing or matching. The award ceiling listed is $200,000. The eligible applicant pool is broad and includes many types of U.S. domestic organizations as well as certain non-U.S. entities. Eligible applicants include state, county, city/township, and special district governments; independent school districts; public housing authorities/Indian housing authorities; public and private institutions of higher education; nonprofits with or without 501(c)(3) status (with the noted exceptions in the listing); for-profit organizations other than small businesses; and small businesses. The eligibility language also explicitly includes a wide range of institution types and community-based entities, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and certain eligible federal agencies. Foreign (non-U.S.) organizations are also listed as eligible, which signals that NIH was open to applications from non-domestic entities under the terms of the announcement.
The opportunity was posted on March 27, 2015, with an original and current closing date of May 7, 2018, and an archive date of June 7, 2018, meaning it is no longer open for new applications under that specific announcement version. The program is associated with CFDA number 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), reflecting its alignment with NIH research funding in kidney and related disease areas. For full details, the announcement pointed applicants to the NIH grants guide page (http://grants.nih.gov/grants/guide/pa-files/PAR-15-161.html). The listed support contact for access or linking issues was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Frequently Asked Questions (FAQs): Pilot and Feasibility Clinical Research Grants in Kidney Diseases (R21) - PAR 15-161
1) What is this grant opportunity?
This opportunity is the NIH Pilot and Feasibility Clinical Research Grants in Kidney Diseases (R21) program under Funding Opportunity Number (FON) PAR 15-161. It is a discretionary NIH grant program intended to support early-stage, small-scale clinical and translational research projects focused on kidney diseases.
2) What NIH grant mechanism does it use?
It uses the NIH Exploratory/Developmental Research Grant mechanism (R21). R21 awards are typically used for innovative, potentially high-impact projects that are not yet ready for a large, definitive study.
3) What is the main purpose of an R21 in this program?
The main purpose is to help investigators generate preliminary clinical evidence, refine study methods, test feasibility, and/or collect early signals of efficacy that can justify and inform a later full-scale clinical study.
4) What kinds of research does this FOA encourage?
The FOA encourages pilot and feasibility work across a broad range of human-focused kidney disease research approaches, including clinical and translational studies, epidemiological investigations, and clinical trials.
5) Does the program support clinical trials?
Yes. The description explicitly includes clinical trials among the encouraged research approaches, including smaller randomized studies used to estimate effect sizes and optimize protocols.
6) What are examples of projects that could fit this opportunity?
Examples described include testing a new diagnostic strategy in a limited cohort, evaluating the practicality of recruiting and retaining a particular patient population, collecting early data on a preventive or therapeutic intervention, or running a smaller randomized study to estimate effect sizes and optimize protocols.
7) What does NIH mean by "pilot and feasibility" in this context?
In practical terms, it refers to targeted proof-of-concept work designed to reduce uncertainty early on. This includes studies that refine methods, test recruitment/retention plans, assess operational practicality, and gather early clinical signals that can support a larger follow-up study.
8) What does "clinically meaningful and translational" imply for proposed research?
It implies that the research questions should have clear clinical relevance and translational potential, with the possibility of improving patient care, influencing clinical practice, or having substantial public health relevance if later validated at scale.
9) Is this award intended to be a stepping-stone to larger studies?
Yes. NIH anticipates that successful R21 projects may evolve into larger efforts such as full-scale epidemiological studies, expanded diagnostic validation studies, or randomized clinical trials for diagnosis, prevention, or treatment of kidney diseases.
10) Is this funding a grant or a contract?
This opportunity is a grant, not a contract.
11) Is cost sharing or matching required?
No. The listing states that cost sharing or matching is not required.
12) What is the award ceiling for this opportunity?
The award ceiling listed is $200,000.
13) Who is eligible to apply?
The eligible applicant pool is broad. It includes many types of U.S. domestic organizations as well as certain non-U.S. entities. Eligible applicants include state, county, city/township, and special district governments; independent school districts; public housing authorities/Indian housing authorities; public and private institutions of higher education; nonprofits with or without 501(c)(3) status (with noted exceptions in the listing); for-profit organizations other than small businesses; and small businesses.
14) Are minority-serving institutions and community-based organizations included in eligibility?
Yes. The eligibility language explicitly includes a wide range of institution types and community-based entities, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), and faith-based or community-based organizations.
15) Are U.S. territories or possessions included?
Yes. U.S. territories or possessions are explicitly listed among eligible entities.
16) Are federal agencies eligible?
Certain eligible federal agencies are listed as eligible applicants under the announcement.
17) Are foreign (non-U.S.) organizations eligible to apply?
Yes. Foreign (non-U.S.) organizations are listed as eligible, indicating NIH was open to applications from non-domestic entities under the terms of the announcement.
18) When was this opportunity posted?
It was posted on March 27, 2015.
19) What was the closing date and is it still open?
The original and current closing date listed was May 7, 2018. The archive date was June 7, 2018. This means it is no longer open for new applications under that specific announcement version.
20) What CFDA number is associated with this program?
The program is associated with CFDA number 93.847, titled Diabetes, Digestive, and Kidney Diseases Extramural Research.
21) Where were applicants directed to find full details?
Applicants were directed to the NIH Grants Guide page at: http://grants.nih.gov/grants/guide/pa-files/PAR-15-161.html
22) Who was the listed support contact for access or linking issues?
The listed support contact for access or linking issues was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
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Applicants also applied for:
Applicants who have applied for this opportunity (PAR 15 161) also looked into and applied for these:
| Funding Opportunity |
|---|
| Pilot and Feasibility Clinical Research Grants in Urologic Disorders (R21) Apply for PAR 15 162 Funding Number: PAR 15 162 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $200,000 |
| New Directions in Hematology Research (SHINE II) (R01) Apply for PAS 15 168 Funding Number: PAS 15 168 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $200,000 |
| Secondary Analyses in Obesity, Diabetes and Digestive and Kidney Diseases (R21) Apply for PA 15 169 Funding Number: PA 15 169 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $200,000 |
| Pilot and Feasibility Clinical Trials in Diabetes, and Endocrine and Metabolic Diseases (R21) Apply for PA 15 176 Funding Number: PA 15 176 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $200,000 |
| Interdisciplinary Training in Bioinformatics and Diabetes, Obesity and Metabolic Disease (T32) Apply for PAR 15 182 Funding Number: PAR 15 182 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Career Development Programs in Diabetes Research for Pediatric Endocrinologists (K12) Apply for RFA DK 15 006 Funding Number: RFA DK 15 006 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Translational Research to Improve Outcomes in Kidney Diseases (R18) Apply for RFA DK 15 009 Funding Number: RFA DK 15 009 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $225,000 |
| Integrated Food Defense Apply for RFA FD 15 022 Funding Number: RFA FD 15 022 Agency: Food Drug Administration Category: Food and Nutrition Health Funding Amount: $100,000 |
| Integrated Food Safety System Online Collaboration Development (U18) Apply for RFA FD 15 024 Funding Number: RFA FD 15 024 Agency: Food Drug Administration Category: Food and Nutrition Health Funding Amount: $680,000 |
| FDA Drug Residue Cooperative Agreement Program (U18) Apply for RFA FD 15 025 Funding Number: RFA FD 15 025 Agency: Food Drug Administration Category: Food and Nutrition Health Funding Amount: $125,000 |
| Limited Competition Advancing Conformance with the Voluntary National Retail Food Regulatory Program Standards (VNRFRPS) (U18) Apply for RFA FD 15 018 Funding Number: RFA FD 15 018 Agency: Food Drug Administration Category: Food and Nutrition Health Funding Amount: $70,000 |
| Implementation of the Animal Feed Regulatory Program Standards (AFRPS) (U18) Apply for RFA FD 15 021 Funding Number: RFA FD 15 021 Agency: Food Drug Administration Category: Food and Nutrition Health Funding Amount: $750,000 |
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| Adherence Studies in Adolescents with Chronic Kidney or Urologic Diseases (R01) Apply for RFA DK 15 017 Funding Number: RFA DK 15 017 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $450,000 |
| NIDDK Centers for Diabetes Translation Research (P30) Apply for RFA DK 15 003 Funding Number: RFA DK 15 003 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Expanding Course Offerings for State and Local Regulators in the Integrated Food Safety System (U18) Apply for RFA FD 15 039 Funding Number: RFA FD 15 039 Agency: Food Drug Administration Category: Food and Nutrition Health Funding Amount: $1,000,000 |
| A Community Research Resource of Microbiome Derived Factors Modulating Host Physiology in Obesity, Digestive and Liver Diseases, and Nutrition (R24) Apply for RFA DK 15 012 Funding Number: RFA DK 15 012 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Exploratory Studies for Delineating Microbiome Host Interactions in Obesity, Digestive and Liver Diseases and Nutrition (R21) Apply for RFA DK 15 013 Funding Number: RFA DK 15 013 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $200,000 |
| Exploration of the Roles of Brown and Beige Adipose Tissue in Humans (R01) Apply for RFA DK 15 031 Funding Number: RFA DK 15 031 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Expanding FDAs Produce Safety and Instructor Skills Training under the Food Safety Modernization Act Apply for RFA FD 15 041 Funding Number: RFA FD 15 041 Agency: Food Drug Administration Category: Food and Nutrition Health Funding Amount: $2,000,000 |
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