Opportunity Information: Apply for RFA DK 12 003
Apply for RFA DK 12 003
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Planning Centers for Interdisciplinary Research in Benign Urology (IR BU) (P20)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on Dec 21, 2011 and posted on Dec 21, 2011.
- Applicants must submit their applications by Mar 20, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Public housing authorities/Indian housing authorities Small businesses Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) For profit organizations other than small businesses County governments State governments City or township governments Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The Planning Centers for Interdisciplinary Research in Benign Urology (IR BU) (P20) funding opportunity (RFA-DK-12-003) is an NIDDK initiative designed to kick-start and organize interdisciplinary research programs focused on benign urology, particularly the causes and biology behind lower urinary tract symptoms (LUTS). NIDDK is aiming this program at a major bottleneck in the field: common symptoms like urinary frequency, urgency, dysuria, and terminal dribbling are largely descriptive, and clinicians and researchers often cannot confidently map those symptoms back to a specific cause, a specific lower urinary tract organ or tissue, the supporting structures, or the peripheral and central nervous system pathways involved. The announcement also highlights a second, related gap: limited basic knowledge about lower urinary tract development and normal physiology has slowed progress in understanding disease mechanisms and in developing better strategies to prevent, diagnose, or treat LUTS.
The core scientific emphasis is on integrative, systems-minded research rather than narrow, single-discipline projects. These planning centers are meant to foster broad programs that connect multiple levels of biology and multiple relevant organ systems. NIDDK explicitly encourages research that can integrate organ-specific development and genetics with studies of structure and function, as well as physiology and pathophysiology. Importantly, the opportunity also calls for in vivo studies that help clarify how urologic organs and tissues may interact with non-urologic organs and tissues, reflecting an interest in whole-organism mechanisms and cross-system influences that could contribute to symptoms. In practical terms, an application is expected to lay out a coherent plan for bringing together these different perspectives into a unified research direction that can mature into a stronger, longer-term center or program of research.
From a program structure standpoint, each IR BU Center supported under this P20 mechanism is constrained to one Scientific Project, meaning applicants are not proposing multiple independent projects under the same umbrella. Instead, the expectation is that the center is built around a single, well-justified scientific theme or project that benefits from interdisciplinary planning and coordination. Every center application must also include an Administrative Core, which typically covers leadership, governance, coordination, communication across participating investigators, and management of milestones and resources. In addition, each center must include an Educational Enrichment Program, signaling that NIDDK wants these planning centers to strengthen the local and broader research environment through activities like seminars, workshops, visiting speakers, mentoring efforts, cross-training opportunities, or other structured approaches that build interdisciplinary capacity in benign urology research.
The teams are expected to be composed of established investigators and to span basic science, urology, and other relevant disciplines. This reflects an intent to move beyond siloed approaches and to assemble groups capable of bridging fundamental biology with clinically meaningful questions. The solicitation is essentially trying to create a platform where mechanistic expertise (developmental biology, genetics, neurobiology, physiology, tissue structure and function) and clinical insight (urology, symptom phenotyping, patient-oriented perspectives) can be coordinated to generate clearer links between symptoms and underlying etiologies.
Administratively, this is a discretionary grant opportunity from the National Institutes of Health, specifically NIDDK, listed under CFDA 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research). The program does not require cost sharing or matching. The opportunity was posted on December 21, 2011, with an original and current closing date of March 20, 2012, and an archive date of April 20, 2012, indicating it is an older, archived solicitation rather than an active current call. The estimated total funding for the opportunity was $1,000,000, with an award ceiling of $200,000 per award.
Eligibility is broad and includes many organization types across the public, private, nonprofit, and academic sectors. Eligible applicants include public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status), for-profit organizations (including small businesses), and a wide range of government entities (state, county, city/township, special district). The eligibility list also includes tribal governments and tribal organizations, public housing authorities/Indian housing authorities, independent school districts, and various mission-serving institutions such as HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and tribally controlled colleges and universities. Faith-based and community-based organizations and regional organizations are also included. Notably, non-U.S. entities (foreign institutions) are eligible to apply, and foreign components of U.S. organizations are allowed as defined by NIH policy, which underscores NIDDK's openness to international expertise where it strengthens the interdisciplinary research plan.
The full funding announcement and details were made available through the NIH grants guide (link provided in the source), and NIH’s Office of Extramural Research webmaster contacts were provided for technical access issues.
Frequently Asked Questions (FAQs)
What is the Planning Centers for Interdisciplinary Research in Benign Urology (IR BU) (P20) opportunity?
This opportunity (RFA-DK-12-003) is an NIDDK initiative that supports P20 planning centers intended to kick-start and organize interdisciplinary research programs in benign urology, with a strong emphasis on understanding the causes and biology behind lower urinary tract symptoms (LUTS).
Which NIH institute sponsors this program?
The program is sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), a component of the National Institutes of Health (NIH).
What is the main scientific problem this initiative is trying to address?
NIDDK is targeting a major bottleneck in benign urology research: common LUTS (for example, urinary frequency, urgency, dysuria, and terminal dribbling) are often descriptive, and clinicians and researchers frequently cannot map these symptoms confidently to a specific cause, a specific lower urinary tract organ or tissue, the supporting structures, or the peripheral and central nervous system pathways involved.
What additional research gap does the announcement highlight?
The announcement also points to limited basic knowledge about lower urinary tract development and normal physiology, which has slowed progress in understanding disease mechanisms and in developing improved prevention, diagnostic, and treatment strategies for LUTS.
What kinds of research approaches are encouraged?
The scientific emphasis is on integrative, systems-minded research rather than narrow, single-discipline projects. The opportunity encourages research that connects multiple levels of biology and multiple relevant organ systems.
Does the opportunity encourage integration across biological topics (for example, genetics and physiology)?
Yes. NIDDK explicitly encourages approaches that integrate organ-specific development and genetics with studies of structure and function, as well as physiology and pathophysiology, within a unified research direction.
Are in vivo studies specifically mentioned?
Yes. The opportunity calls for in vivo studies that help clarify how urologic organs and tissues may interact with non-urologic organs and tissues, reflecting interest in whole-organism mechanisms and cross-system influences that could contribute to symptoms.
What is the expected scope of an application?
An application is expected to lay out a coherent plan for bringing multiple perspectives together into a unified interdisciplinary research direction that can mature into a stronger, longer-term center or program of research.
How many scientific projects can be included in a single P20 center application?
Each IR BU Center supported under this P20 mechanism is constrained to one Scientific Project. Applicants are not proposing multiple independent projects under the same umbrella.
What is the center expected to be built around?
The center is expected to be organized around a single, well-justified scientific theme or project that benefits from interdisciplinary planning and coordination.
Is an Administrative Core required?
Yes. Every center application must include an Administrative Core, which typically covers leadership, governance, coordination, communication across participating investigators, and management of milestones and resources.
Is an Educational Enrichment Program required?
Yes. Each center must include an Educational Enrichment Program, reflecting NIDDK's goal of strengthening the local and broader research environment and building interdisciplinary capacity in benign urology research.
What types of activities might fit under the Educational Enrichment Program?
The announcement indicates examples such as seminars, workshops, visiting speakers, mentoring efforts, cross-training opportunities, and other structured activities that build interdisciplinary capacity in benign urology research.
What kinds of investigators and disciplines are expected on the team?
Teams are expected to be composed of established investigators and to span basic science, urology, and other relevant disciplines. The intent is to bridge fundamental biology with clinically meaningful questions.
What kinds of expertise does NIDDK want to see coordinated in these planning centers?
The solicitation is aimed at coordinating mechanistic expertise (such as developmental biology, genetics, neurobiology, physiology, and tissue structure and function) with clinical insight (such as urology, symptom phenotyping, and patient-oriented perspectives) to generate clearer links between symptoms and underlying etiologies.
What is the funding agency and grant type?
This is a discretionary grant opportunity from NIH (specifically NIDDK) under the P20 mechanism.
What is the CFDA number associated with this opportunity?
The opportunity is listed under CFDA 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research).
Is cost sharing or matching required?
No. The opportunity states that it does not require cost sharing or matching.
How much total funding was estimated for this opportunity?
The estimated total funding for the opportunity was $1,000,000.
What is the maximum award amount per award?
The award ceiling was $200,000 per award.
When was the opportunity posted and when did it close?
The opportunity was posted on December 21, 2011. The original and current closing date was March 20, 2012, and the archive date was April 20, 2012.
Is this an active funding opportunity?
Based on the provided dates (closing date in March 2012 and archive date in April 2012), this appears to be an older, archived solicitation rather than an active current call.
Who is eligible to apply?
Eligibility is broad and includes many organization types across public, private, nonprofit, for-profit, academic, and government sectors. Eligible applicants include public and private institutions of higher education, nonprofit organizations (with and without 501(c)(3) status), for-profit organizations (including small businesses), and government entities such as state, county, city/township, and special district governments.
Are tribal governments and tribal organizations eligible?
Yes. The eligibility list includes tribal governments and tribal organizations, as well as tribally controlled colleges and universities.
Are mission-serving institutions included in eligibility?
Yes. The eligibility list includes a range of mission-serving institutions such as HBCUs, Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and tribally controlled colleges and universities.
Are faith-based, community-based, or regional organizations eligible?
Yes. Faith-based and community-based organizations and regional organizations are included in the eligibility list.
Are non-U.S. (foreign) institutions eligible to apply?
Yes. Non-U.S. entities (foreign institutions) are eligible to apply, and foreign components of U.S. organizations are allowed as defined by NIH policy.
Where were the official announcement details made available?
The full funding announcement and details were made available through the NIH grants guide (with a link provided in the source material).
Who is listed for technical access issues related to the announcement?
NIH's Office of Extramural Research webmaster contacts were provided for technical access issues.
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| The Collaborative Islet Transplantation Registry (UC4) Apply for RFA DK 12 002 Funding Number: RFA DK 12 002 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $530,000 |
| NIDDK Short Term Education Program for Underrepresented Persons (STEP UP) (R25) Apply for RFA DK 12 005 Funding Number: RFA DK 12 005 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $158,000 |
| The Human Islet Distribution Coordinating Center (UC4) Apply for RFA DK 12 001 Funding Number: RFA DK 12 001 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $2,000,000 |
| Secondary Analyses in Obesity, Diabetes and Digestive and Kidney Diseases (R21) Apply for PA 12 125 Funding Number: PA 12 125 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $200,000 |
| Pilot and Feasibility Clinical Research Grants in Diabetes, and Endocrine and Metabolic Diseases (R21) Apply for PA 12 157 Funding Number: PA 12 157 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $200,000 |
| Translational Research to Improve Obesity and Diabetes Outcomes (R18) Apply for PAR 12 172 Funding Number: PAR 12 172 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Planning Grants for Translational Research to Improve Obesity and Diabetes Outcomes (R34) Apply for PAR 12 173 Funding Number: PAR 12 173 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $150,000 |
| Promoting Organ and Tissue Donation Among Diverse Populations (R01) Apply for RFA DK 12 006 Funding Number: RFA DK 12 006 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $150,000 |
| Limited Competition for the Continuation of the Halt Polycystic Kidney Disease Trials Data Coordinating Center (DCC) (U01) Apply for RFA DK 12 505 Funding Number: RFA DK 12 505 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
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| Renal Function and Chronic Kidney Disease in Aging (R01) Apply for PA 12 211 Funding Number: PA 12 211 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| George M. OBrien Kidney Research Core Centers (P30) Apply for RFA DK 12 008 Funding Number: RFA DK 12 008 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $750,000 |
| Research Enhancement for NIDDK Hematology Grantees (Admin Supp) Apply for PA 12 242 Funding Number: PA 12 242 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
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| Lymphatics in Health and Disease in the Digestive, Urinary, Cardiovascular and Pulmonary Systems (R01) Apply for PAR 12 259 Funding Number: PAR 12 259 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $250,000 |
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