Opportunity Information: Apply for PAR 13 371

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Planning for a National Center for Particle Beam Radiation Therapy Research (P20)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.395 Cancer Treatment Research.
  • This funding opportunity was created on Nov 6, 2013 and posted on Oct 17, 2013.
  • Applicants must submit their applications by Feb 24, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $500,000.00 in funding.
  • Eligible applicants include: Public and State controlled institutions of higher education For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses City or township governments Independent school districts Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Special district governments State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) County governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed
Apply for PAR 13 371

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Opportunity Summary:

The NIH funding opportunity PAR-13-371, titled "Planning for a National Center for Particle Beam Radiation Therapy Research (P20)," is a planning grant meant to help organizations lay the groundwork for a dedicated research center focused on particle beam radiation therapy (PBRT). The central idea is to fund the coordination, partnerships, and research setup needed to build a strong, clinically relevant PBRT research program that can later compete for larger, long-term center funding. This FOA is not intended to pay for construction, acquisition, or operation of a PBRT clinical treatment facility. Instead, the proposed research center must be planned as an adjunct to a separate, already created and independently funded, sustainable clinical PBRT facility.

The planned center is expected to support clinically meaningful research using proton beams and heavier ion beams, with carbon ions specifically mentioned as an example but not a requirement. NIH is looking for planning activities that bring together the specialized expertise and infrastructure needed to run a serious PBRT research agenda alongside clinical operations. That includes organizing multidisciplinary teams that typically span physics, engineering, biology, and medicine, and ensuring the overall research program is capable of addressing the technical and biological questions that arise when delivering particle therapy to patients. Examples of research-supporting resources that may be part of the plan include laboratory capabilities such as cell culture space, animal research resources (vivarium), and clinical support resources such as anesthesia capacity for pediatric patients, reflecting the practical realities of performing PBRT-related clinical and translational research.

A key requirement is that applicants propose at least one pilot project as part of the planning effort. The pilot work needs to be directly aligned with establishing a PBRT research agenda and can fall into areas such as particle beam delivery systems, dosimetry, radiation biology, or translational preclinical studies. In practice, this means the application should not be purely administrative or conceptual; it must include a concrete, scientifically grounded pilot effort that demonstrates feasibility, helps define the center's direction, and positions the team to launch a broader portfolio of PBRT research once the center is fully developed.

The broader goal is national in scope: NIH expects that these planning awards will help create a research resource with the maturity and competitiveness to secure future funding for a specialized PBRT research center. The emphasis is on building the right combination of people, processes, and facilities planning so that basic research, translational work, and clinical investigation can be integrated with and complementary to the clinical PBRT facility. In other words, the planning grant is meant to help applicants assemble the scientific vision, governance and collaboration structure, and enabling research environment that would allow PBRT studies to move efficiently from engineering and physics into biology and ultimately into patient-centered clinical research.

Administratively, this is a discretionary NIH grant using the P20 mechanism, with an award ceiling listed at $500,000 and no cost-sharing or matching requirement. The funding activity category is listed under Education and Health, with CFDA number 93.395 (Cancer Treatment Research). The opportunity was posted October 17, 2013, with a final closing date of February 24, 2014, and it was archived March 24, 2014.

Eligibility is broad and includes many types of U.S.-based organizations such as public and private institutions of higher education, nonprofit and for-profit organizations (including small businesses), tribal organizations, state and local governments, school districts, and public housing authorities, with additional eligibility notes calling out groups such as HBCUs, Hispanic-serving institutions, AANAPISIs, TCCUs, faith-based or community-based organizations, regional organizations, and eligible federal agencies. Non-U.S. entities and non-U.S. components of U.S. organizations are not eligible to apply, although foreign components (as defined in NIH policy) are allowed. The sponsoring agency is the National Institutes of Health, and the full announcement was hosted on the NIH grants website under the PAR-13-371 listing.

Frequently Asked Questions (FAQs): PAR-13-371 (P20) Planning for a National Center for Particle Beam Radiation Therapy Research

1) What is PAR-13-371?

PAR-13-371 is an NIH funding opportunity titled "Planning for a National Center for Particle Beam Radiation Therapy Research (P20)." It supports planning activities to lay the groundwork for a dedicated research center focused on particle beam radiation therapy (PBRT).

2) What is the main purpose of this funding opportunity?

The purpose is to fund coordination, partnerships, and research setup needed to build a strong, clinically relevant PBRT research program that can later compete for larger, long-term center funding.

3) Is this grant meant to fund an operational PBRT center long-term?

No. This is a planning grant (P20) intended to prepare an organization to become competitive for future, larger center-level funding.

4) Does this FOA pay for construction or purchase of a particle therapy facility?

No. The FOA is not intended to pay for construction, acquisition, or operation of a PBRT clinical treatment facility.

5) Do applicants need access to an existing clinical PBRT facility?

Yes. The proposed research center must be planned as an adjunct to a separate, already created and independently funded, sustainable clinical PBRT facility.

6) What types of particle beams are expected to be supported by the planned research center?

The planned center is expected to support clinically meaningful research using proton beams and heavier ion beams. Carbon ions are specifically mentioned as an example, but they are not a requirement.

7) What kinds of planning activities does NIH expect under this opportunity?

NIH expects planning activities that bring together specialized expertise and infrastructure needed to run a serious PBRT research agenda alongside clinical operations. This includes organizing multidisciplinary teams and planning the research environment needed to address technical and biological questions related to delivering particle therapy to patients.

8) What disciplines are typically expected to be involved in a PBRT research planning effort?

The FOA highlights multidisciplinary teams that typically span physics, engineering, biology, and medicine.

9) What kinds of research-supporting resources might be included in the plan?

Examples mentioned include laboratory capabilities such as cell culture space, animal research resources (vivarium), and clinical support resources such as anesthesia capacity for pediatric patients, reflecting practical needs for PBRT-related clinical and translational research.

10) Is a pilot project required?

Yes. A key requirement is that applicants propose at least one pilot project as part of the planning effort.

11) What should the required pilot project focus on?

The pilot work must be directly aligned with establishing a PBRT research agenda and demonstrating feasibility while helping define the future center's direction.

12) What research areas can the pilot project fall under?

Examples include particle beam delivery systems, dosimetry, radiation biology, and translational preclinical studies.

13) Can an application be purely administrative or conceptual?

No. The FOA indicates the application should not be purely administrative or conceptual; it must include a concrete, scientifically grounded pilot effort.

14) What is the broader vision NIH has for awards made under this FOA?

The broader goal is national in scope. NIH expects these planning awards to help create a research resource mature and competitive enough to secure future funding for a specialized PBRT research center.

15) How should the planned research program relate to clinical operations?

The planning effort should support integration so that basic research, translational work, and clinical investigation are complementary to (and can operate alongside) the clinical PBRT facility.

16) What grant mechanism is used for this opportunity?

This is a discretionary NIH grant using the P20 mechanism.

17) What is the maximum award amount mentioned in the opportunity?

The award ceiling is listed at $500,000.

18) Is cost sharing or a match required?

No. The opportunity states there is no cost-sharing or matching requirement.

19) What is the funding activity category and CFDA number?

The funding activity category is listed under Education and Health, and the CFDA number is 93.395 (Cancer Treatment Research).

20) Who is the sponsoring agency?

The sponsoring agency is the National Institutes of Health (NIH).

21) When was this opportunity posted and when did it close?

The opportunity was posted October 17, 2013, and had a final closing date of February 24, 2014.

22) Is this funding opportunity still active?

No. It was archived March 24, 2014.

23) What types of U.S.-based organizations are eligible to apply?

Eligibility is broad and includes U.S.-based public and private institutions of higher education, nonprofit and for-profit organizations (including small businesses), tribal organizations, state and local governments, school districts, and public housing authorities.

24) Are specific institution types explicitly noted as eligible?

Yes. Additional eligibility notes call out groups such as HBCUs, Hispanic-serving institutions, AANAPISIs, TCCUs, faith-based or community-based organizations, regional organizations, and eligible federal agencies.

25) Can non-U.S. organizations apply?

No. Non-U.S. entities and non-U.S. components of U.S. organizations are not eligible to apply.

26) Are any foreign components allowed under NIH policy?

Yes. Foreign components (as defined in NIH policy) are allowed.

27) Where was the full announcement published?

The full announcement was hosted on the NIH grants website under the PAR-13-371 listing.

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