Opportunity Information: Apply for RFA DK 13 002
Apply for RFA DK 13 002
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Planning Grants for Translating CKD Research into Improved Clinical Outcomes (R34)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on Apr 15, 2013 and posted on Apr 15, 2013.
- Applicants must submit their applications by Jul 30, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,450,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $225,000.00 in funding.
- Eligible applicants include: Small businesses Independent school districts For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) State governments Public housing authorities/Indian housing authorities Private institutions of higher education City or township governments Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) County governments Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
Planning Grants for Translating CKD Research into Improved Clinical Outcomes (R34) is a National Institutes of Health opportunity issued by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to support early-stage planning work for clinical studies focused on chronic kidney disease (CKD). The intent is not to fund a full-scale definitive trial right away, but to fund the preparatory work needed to determine whether a proposed clinical trial is feasible and well-designed before moving into a larger, more expensive effectiveness study. In practical terms, this R34 mechanism is meant to help applicants build a strong, trial-ready foundation by resolving key uncertainties about implementation, recruitment, measurement, logistics, and overall study readiness.
The program specifically targets interventions aimed at the prevention, treatment, and management of CKD and/or its complications. A central theme is translation into real-world clinical outcomes: NIDDK is looking for approaches that have a high likelihood of being widely adopted and sustained across diverse health care settings, rather than strategies that only work under highly controlled research conditions. Another key emphasis is equity and reach. Projects are expected to be relevant to, and designed with, individuals and communities at the highest risk for CKD, with an eye toward interventions that can function effectively across different systems of care and community contexts.
A major eligibility and scientific requirement is that the intervention being planned for testing must be based on widely accepted approaches that have already shown efficacy in prior clinical trials. In other words, applicants are not being asked to invent an unproven treatment or start from scratch; instead, they are expected to take an intervention that has demonstrated benefit under controlled conditions and plan the next step: testing its effectiveness, feasibility, and potential for sustained implementation in typical practice settings. The R34 is therefore oriented toward bridging the gap between what is known to work in research trials and what can be implemented at scale to improve outcomes for patients with CKD.
From an administrative standpoint, this is a discretionary grant opportunity with no cost-sharing or matching requirement. The total estimated funding for the announcement is $1,450,000, with an award ceiling of $225,000 per award. The funding opportunity number is RFA-DK-13-002, and it was posted on April 15, 2013, with an application closing date of July 30, 2013 (and an archive date of August 30, 2013). The associated CFDA number is 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research).
Eligibility is broad and includes many types of organizations, reflecting NIH's interest in supporting planning efforts across academic, clinical, governmental, nonprofit, and private-sector environments. Eligible applicants include public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) nonprofits), for-profit organizations (including small businesses), state and local governments (including county, city/township, special district governments), public housing authorities/Indian housing authorities, tribal organizations (including federally recognized tribes and other tribal entities), and school districts. The announcement also explicitly includes a range of mission- and community-focused institutions and organizations such as HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and Asian American and Native American Pacific Islander Serving Institutions. Foreign organizations and foreign institutions are also eligible to apply, and non-U.S. components of U.S. organizations may participate; foreign components are allowed consistent with NIH policy.
Overall, this opportunity is best understood as NIH support for the nuts-and-bolts planning needed to responsibly launch an effectiveness-oriented CKD intervention trial that is realistic, scalable, and built for sustained uptake. Applicants are expected to focus on feasibility and readiness to test interventions that already have evidence behind them, with a clear line of sight to improving clinical outcomes in the populations and settings where CKD burden is greatest. For full details, NIH pointed applicants to the official announcement page at http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-13-002.html, and provided NIH Office of Extramural Research (OER) webmaster contacts for access or linking issues.
Frequently Asked Questions (FAQs)
What is the "Planning Grants for Translating CKD Research into Improved Clinical Outcomes (R34)" opportunity?
This is a National Institutes of Health (NIH) funding opportunity issued by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). It supports early-stage planning activities needed to translate chronic kidney disease (CKD) research into improved real-world clinical outcomes.
What is the main purpose of this R34 planning grant?
The R34 is intended to fund preparatory work that helps determine whether a proposed CKD-focused clinical study is feasible and well-designed before launching a larger and more expensive effectiveness study. It is meant to help applicants build a trial-ready foundation by addressing uncertainties around implementation, recruitment, measurement, logistics, and overall study readiness.
Is this grant meant to fund a full-scale definitive clinical trial?
No. The intent is not to fund a full-scale definitive trial immediately. Instead, it funds the planning work needed to responsibly develop and refine a study so it is ready for a future, larger effectiveness trial.
What disease area and topic does this opportunity focus on?
The focus is on chronic kidney disease (CKD), including interventions aimed at prevention, treatment, and management of CKD and/or its complications, with an emphasis on improving clinical outcomes in real-world care settings.
What types of interventions does NIDDK want to see planned under this R34?
NIDDK is targeting interventions that can translate into real-world clinical outcomes and have a high likelihood of being widely adopted and sustained across diverse health care settings. The program emphasizes approaches that can work beyond highly controlled research conditions.
Does the planned intervention need to already have evidence of efficacy?
Yes. A major scientific and eligibility requirement is that the intervention being planned for testing must be based on widely accepted approaches that have already shown efficacy in prior clinical trials. The opportunity is not intended for inventing or testing an unproven treatment from scratch.
What is meant by "translation into real-world clinical outcomes" in this program?
It refers to moving from interventions that work under controlled research conditions toward testing and implementing those interventions in typical practice settings. The goal is to plan for effectiveness, feasibility, and sustained implementation in real-world environments.
What are the key planning uncertainties this R34 is meant to address?
The announcement highlights planning needs such as implementation approach, recruitment strategy and feasibility, measurement and outcome assessment, logistics, and overall readiness to launch an effectiveness-oriented clinical study.
Is there an emphasis on equity and reach in the planned projects?
Yes. Projects are expected to be relevant to and designed with individuals and communities at the highest risk for CKD. The opportunity emphasizes interventions that can function effectively across different systems of care and community contexts.
How much total funding is estimated for this opportunity?
The total estimated funding for the announcement is $1,450,000.
What is the maximum award amount (award ceiling) per grant?
The award ceiling is $225,000 per award.
Is cost-sharing or matching required?
No. This is a discretionary grant opportunity with no cost-sharing or matching requirement.
What is the funding opportunity number for this announcement?
The funding opportunity number is RFA-DK-13-002.
When was the opportunity posted and when was the application due?
It was posted on April 15, 2013. The application closing date was July 30, 2013. The archive date was August 30, 2013.
What is the CFDA number associated with this opportunity?
The associated CFDA number is 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research).
Who is the sponsoring NIH Institute for this opportunity?
The sponsoring Institute is the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
What types of organizations are eligible to apply?
Eligibility is broad and includes public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) nonprofits), for-profit organizations (including small businesses), state and local governments (including county, city/township, and special district governments), public housing authorities/Indian housing authorities, tribal organizations (including federally recognized tribes and other tribal entities), and school districts.
Are mission- and community-focused institutions explicitly included as eligible applicants?
Yes. The announcement explicitly includes HBCUs, Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and Asian American and Native American Pacific Islander Serving Institutions.
Are foreign organizations eligible to apply?
Yes. Foreign organizations and foreign institutions are eligible to apply. In addition, non-U.S. components of U.S. organizations may participate, and foreign components are allowed consistent with NIH policy.
Where can applicants find the official announcement details?
The official announcement page is listed as http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-13-002.html.
Who should be contacted if there are access or linking issues with the announcement page?
The opportunity notes NIH Office of Extramural Research (OER) webmaster contacts for access or linking issues.
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Applicants also applied for:
Applicants who have applied for this opportunity (RFA DK 13 002) also looked into and applied for these:
| Funding Opportunity |
|---|
| Biomarkers for Diabetes, Digestive, Kidney and Urologic Diseases Using Biosamples from the NIDDK Repository (R01) Apply for PAR 13 228 Funding Number: PAR 13 228 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $250,000 |
| United States Renal Data System (USRDS) Special Study Centers (U01) Apply for RFA DK 13 008 Funding Number: RFA DK 13 008 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Type 1 Diabetes TrialNet Clinical Network Hub (U01) Apply for RFA DK 13 009 Funding Number: RFA DK 13 009 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $2,000,000 |
| Type 1 Diabetes TrialNet Clinical Centers (U01) Apply for RFA DK 13 010 Funding Number: RFA DK 13 010 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $200,000 |
| NIDDK Program Projects (P01) Apply for PAR 13 266 Funding Number: PAR 13 266 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| NIDDK Multi Center Clinical Study Implementation Planning Cooperative Agreements (U34) Apply for PAR 13 268 Funding Number: PAR 13 268 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $225,000 |
| Limited Competition for the Continuation of a National Endoscopic Database (U01) Apply for RFA DK 13 504 Funding Number: RFA DK 13 504 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Diabetes Research Centers (P30) Apply for RFA DK 13 004 Funding Number: RFA DK 13 004 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Continuation of ChiLDReN, the Childhood Liver Disease Research Network (U01) Apply for RFA DK 13 011 Funding Number: RFA DK 13 011 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Limited Competition Continuation of the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN)(U01) Apply for RFA DK 13 503 Funding Number: RFA DK 13 503 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Gut Microbiota Derived Factors in the Integrated Physiology and Pathophysiology of Diseases within NIDDKs Mission (R01) Apply for PAR 13 293 Funding Number: PAR 13 293 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Limited Competition Chronic Kidney Disease (CKD) Biomarkers Consortium Data Coordinating Center (U01) Apply for RFA DK 13 506 Funding Number: RFA DK 13 506 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Collaborative Interdisciplinary Team Science in NIDDK Research Areas (R24) Apply for PAR 13 305 Funding Number: PAR 13 305 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Improving Diabetes Management in Young Children with Type 1 Diabetes (DP3) Apply for RFA DK 13 022 Funding Number: RFA DK 13 022 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $1,400,000 |
| Understanding Barriers and Facilitators to Type 1 Diabetes Management in Adults (DP3) Apply for RFA DK 13 023 Funding Number: RFA DK 13 023 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $5,000,000 |
| Limited Competition of the MAPP Research Network(U01) Apply for RFA DK 13 507 Funding Number: RFA DK 13 507 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Expansion of the MAPP Research Network (U01) Apply for RFA DK 13 025 Funding Number: RFA DK 13 025 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $250,000 |
| Developmental Centers for Interdisciplinary Research in Benign Urology (P20) Apply for RFA DK 13 019 Funding Number: RFA DK 13 019 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $200,000 |
| Translational Research to Improve Diabetes and Obesity Outcomes (R01) Apply for PA 13 352 Funding Number: PA 13 352 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: Case Dependent |
| Harvesting the Neuroimaging Cornucopia for Pancreatic Islet Imaging Reagents for Diabetes Research (DP3) Apply for RFA DK 13 024 Funding Number: RFA DK 13 024 Agency: National Institutes of Health Category: Food and Nutrition Health Funding Amount: $300,000 |
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