Opportunity Information: Apply for CDC RFA GH11 1152

  • The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Planning, Implementation and Evaluation of Comprehensive HIV Prevention Programs in the Republic of South Africa under the President s Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067 Global AIDS.
  • This funding opportunity was created on Mar 25, 2011 and posted on Feb 18, 2011.
  • Applicants must submit their applications by Apr 18, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $85,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $3,000,000.00 in funding.
  • The number of recipients for this funding is limited to 12 candidate(s).
  • Eligible applicants include: For profit organizations other than small businesses Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education County governments Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments.
  • Eligible applicants that can apply for this funding opportunity are Nonprofit with 501C3 IRS status (other than institution of higher education) Nonprofit without 501C3 IRS status (other than institution of higher education) For profit organizations (other than small business) Small, minority, and women owned businesses Universities Colleges Research institutions Hospitals Community based organizations Faith based organizations Federally recognized or state recognized American Indian/Alaska Native tribal governments State and local governments or their Bona Fide Agents (this includes the District of Columbia, the Commonwealth of Puerto Rico, the Virgin Islands, the Commonwealth of the Northern Marianna Islands, American Samoa, Guam, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau) Non domestic (non U.S.) entity Other (specify) A Bona Fide Agent is an agency/organization identified by the state as eligible to submit an application under the state eligibility in lieu of a state application. If applying as a bona fide agent of a state or local government, a letter from the state or local government as documentation of the status is required. Attach with Other Attachment Forms when submitting via www.grants.gov.
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Opportunity Summary:

Planning, Implementation and Evaluation of Comprehensive HIV Prevention Programs in the Republic of South Africa under the President's Emergency Plan for AIDS Relief (PEPFAR) is a CDC-funded cooperative agreement opportunity (Funding Opportunity Number CDC RFA GH11-1152) designed to strengthen HIV prevention efforts across South Africa through coordinated planning, on-the-ground implementation, and rigorous evaluation. The core purpose is to support comprehensive HIV prevention programming that aligns with PEPFAR priorities and is carried out in close collaboration with South African government HIV/AIDS structures at the district, provincial, and national levels. Awardees are expected to work side-by-side with government counterparts and other implementing partners to provide practical programmatic support and technical assistance, with the goal of improving prevention outcomes and ensuring programs are well-managed, evidence-informed, and measurable.

The opportunity is structured as a cooperative agreement, which generally indicates substantial involvement from CDC beyond standard grant oversight. In practice, this typically means awardees will coordinate closely with CDC on strategy, technical approaches, monitoring and evaluation expectations, and alignment with broader PEPFAR and national HIV prevention goals. The announcement emphasizes a full program cycle approach: planning services and strategies, implementing prevention interventions, and evaluating results to understand what is working, for whom, and under what conditions. In some cases, awardees may also provide financial support to other organizations through sub-grants, including to government partners, when that is necessary to achieve program objectives. This design supports a layered implementation model where a primary recipient can strengthen capacity and accelerate delivery through local partners while maintaining accountability for performance.

CDC anticipated making up to 12 awards under this announcement, with an estimated total funding amount of $85,000,000. Individual awards were expected to fall between an award floor of $500,000 and an award ceiling of $3,000,000, indicating that funded projects could range from moderately sized initiatives to large, multi-district efforts depending on scope, geographic coverage, and the proposed technical approach. The Catalog of Federal Domestic Assistance (CFDA) number associated with the program is 93.067 (Global AIDS). No cost sharing or matching requirement was listed, which means applicants were not required to contribute a specific financial match to be eligible.

The eligibility criteria were broad and included many organization types capable of implementing public health programs at scale. Eligible applicants included nonprofits with and without 501(c)(3) status (other than higher education institutions), for-profit organizations (including small businesses and small, minority, and women-owned businesses), universities, colleges, research institutions, hospitals, community-based and faith-based organizations, and U.S. state, local, county, and city governments. It also allowed tribal governments and a range of U.S. territories and affiliated jurisdictions. Importantly, the eligibility list also included non-U.S. (non-domestic) entities, which is highly relevant given the South Africa focus. The announcement also allowed applications from bona fide agents of state or local governments, provided the applicant included a letter documenting that status as part of the submission.

Key administrative details show the lifecycle of the opportunity. It was posted on February 18, 2011, with an original and final closing date of April 18, 2011, and it was archived on May 18, 2011. The funding activity category is health, and the sponsoring agency is the Centers for Disease Control and Prevention. For applicants or stakeholders who needed help accessing the full announcement, the CDC Procurement and Grants Office Technical Information Management Section (TIMS) was listed as the point of contact at 770-488-2700.

Frequently Asked Questions (FAQs)

1) What is this funding opportunity?

This opportunity is a CDC-funded cooperative agreement titled "Planning, Implementation and Evaluation of Comprehensive HIV Prevention Programs in the Republic of South Africa under the President's Emergency Plan for AIDS Relief (PEPFAR)." The Funding Opportunity Number is CDC RFA GH11-1152.

2) Who is the sponsoring agency?

The sponsoring agency is the Centers for Disease Control and Prevention (CDC).

3) What is the main purpose of the program?

The core purpose is to strengthen HIV prevention efforts across South Africa through coordinated planning, on-the-ground implementation, and rigorous evaluation. The program is intended to support comprehensive HIV prevention programming that aligns with PEPFAR priorities and is carried out in close collaboration with South African government HIV/AIDS structures at the district, provincial, and national levels.

4) What does "comprehensive HIV prevention" mean in the context of this announcement?

Based on the announcement description, "comprehensive" refers to supporting a full program cycle approach that includes planning services and strategies, implementing prevention interventions, and evaluating results to understand what is working, for whom, and under what conditions.

5) What type of award is this?

This is a cooperative agreement.

6) What does it mean that this is a cooperative agreement?

The announcement indicates that CDC will have substantial involvement beyond standard grant oversight. In practice, awardees would be expected to coordinate closely with CDC on strategy, technical approaches, monitoring and evaluation expectations, and alignment with broader PEPFAR and national HIV prevention goals.

7) Where will the funded work take place?

The opportunity is focused on the Republic of South Africa and emphasizes collaboration with South African government HIV/AIDS structures at district, provincial, and national levels.

8) What kinds of activities are awardees expected to carry out?

Awardees are expected to support a full program cycle, including:

  • Planning HIV prevention services and strategies
  • Implementing HIV prevention interventions
  • Evaluating results to determine what works and under what conditions
  • Providing practical programmatic support and technical assistance in collaboration with government counterparts and other implementing partners

9) How closely are awardees expected to work with government partners?

The announcement emphasizes close collaboration with South African government HIV/AIDS structures. Awardees are expected to work side-by-side with government counterparts and other implementing partners, providing practical support and technical assistance.

10) Is monitoring and evaluation (M&E) a required part of the program?

Yes. The opportunity description emphasizes rigorous evaluation and measuring results as part of the full program cycle, with attention to understanding what is working, for whom, and under what conditions.

11) Is this opportunity aligned with PEPFAR priorities?

Yes. The program is explicitly framed under PEPFAR and is intended to align with broader PEPFAR goals as well as national HIV prevention goals.

12) Can awardees provide sub-grants to other organizations?

In some cases, awardees may provide financial support to other organizations through sub-grants, including to government partners, when necessary to achieve program objectives. The announcement describes this as a layered implementation model where the primary recipient strengthens capacity and accelerates delivery through local partners while maintaining accountability for performance.

13) How many awards did CDC anticipate making?

CDC anticipated making up to 12 awards under this announcement.

14) What was the estimated total funding amount?

The estimated total funding amount was $85,000,000.

15) What was the expected funding range per award?

Individual awards were expected to range from an award floor of $500,000 to an award ceiling of $3,000,000.

16) Does the announcement require cost sharing or matching funds?

No cost sharing or matching requirement was listed, meaning applicants were not required to contribute a specific financial match to be eligible.

17) What is the CFDA number associated with this opportunity?

The Catalog of Federal Domestic Assistance (CFDA) number is 93.067 (Global AIDS).

18) What is the funding activity category?

The funding activity category is health.

19) Who was eligible to apply?

Eligibility was broad and included many organization types capable of implementing public health programs at scale, including:

  • Nonprofits with and without 501(c)(3) status (other than higher education institutions)
  • For-profit organizations (including small businesses and small, minority, and women-owned businesses)
  • Universities, colleges, and research institutions
  • Hospitals
  • Community-based and faith-based organizations
  • U.S. state, local, county, and city governments
  • Tribal governments
  • U.S. territories and affiliated jurisdictions
  • Non-U.S. (non-domestic) entities

20) Are non-U.S. organizations allowed to apply?

Yes. The eligibility list includes non-U.S. (non-domestic) entities, which is particularly relevant given the focus on South Africa.

21) Can a bona fide agent apply on behalf of a state or local government?

Yes. Applications were allowed from bona fide agents of state or local governments, but the applicant needed to include a letter documenting that status as part of the submission.

22) When was the opportunity posted?

The announcement was posted on February 18, 2011.

23) What were the application deadlines?

The original closing date was April 18, 2011, and the final closing date was also April 18, 2011.

24) Is the opportunity still open?

No. The opportunity was archived on May 18, 2011.

25) Who can be contacted for help accessing the full announcement?

The point of contact listed was the CDC Procurement and Grants Office Technical Information Management Section (TIMS) at 770-488-2700.

26) What are awardees ultimately expected to achieve?

The description emphasizes improving HIV prevention outcomes and ensuring programs are well-managed, evidence-informed, and measurable through coordinated planning, effective implementation, and rigorous evaluation in collaboration with government counterparts and other partners.

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