Opportunity Information: Apply for RFA DK 09 007

  • The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Polycystic Kidney Disease (PKD) Research and Translation Core Centers (P30)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
  • This funding opportunity was created on Dec 23, 2009 and posted on Dec 22, 2009.
  • Applicants must submit their applications by Mar 10, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $4,250,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $750,000.00 in funding.
  • Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Native American tribal governments (Federally recognized) Private institutions of higher education Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Small businesses County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) State governments City or township governments Independent school districts Public and State controlled institutions of higher education Special district governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The Polycystic Kidney Disease (PKD) Research and Translation Core Centers (P30) opportunity (Funding Opportunity Number RFA-DK-09-007) is an NIH grant program run by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to strengthen and accelerate PKD research by funding dedicated “core centers.” The main idea is to support organized hubs that bring together investigators working on both basic science and clinical research in PKD, and to make that work more efficient by building shared infrastructure, expertise, and services. A central emphasis is on translation: helping discoveries about PKD biology move more smoothly from lab findings into tools, approaches, and evidence that can inform clinical practice.

This funding uses the NIH P30 Core Center mechanism, which is designed to support shared resources rather than stand-alone research projects. In practice, these centers are expected to develop and operate core facilities, services, and other centralized resources that multiple investigators can use. The FOA frames these as “shared institutional and national resources,” meaning the centers should not only serve their local research community but also contribute capabilities that benefit PKD research more broadly. The overall goal is to raise the quality, coordination, and productivity of PKD research by reducing duplication, standardizing methods where helpful, and giving researchers reliable access to specialized tools and support that would be hard to maintain within individual labs or single clinical studies.

From a funding standpoint, NIDDK planned to commit up to $4.25 million in total funding in fiscal year 2010, with an expectation of making up to four new or competing awards. The listed award ceiling is $750,000. The opportunity is categorized as discretionary and uses the grant funding instrument. It is associated with CFDA number 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research). There is no cost sharing or matching requirement stated for applicants, which means applicants are not required to provide matching funds as a condition of award under this announcement.

Eligibility is broad and includes many organization types typically permitted under NIH funding, spanning public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (other than small businesses are explicitly listed, though small businesses are also listed separately as eligible), and a wide range of government entities (state, county, city/township, special district governments, independent school districts, and public housing/Indian housing authorities). Tribal governments and tribal organizations are included (both federally recognized tribal governments and other tribal entities are referenced), along with U.S. territories or possessions and regional organizations. The eligibility section also explicitly calls out a number of institution types and community-serving categories, including Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations. Notably, the FOA also indicates that non-domestic (non-U.S.) entities or foreign organizations are eligible, and that eligible agencies of the federal government may apply as well, reflecting NIH’s broader approach to allowing many institutional forms to participate when appropriate to the science and infrastructure being proposed.

Key dates show the opportunity was posted on December 22, 2009 (created December 23, 2009), with an original and current application closing date of March 10, 2010, and an archive date of April 10, 2010. The sponsoring agency is the National Institutes of Health, with NIDDK as the institute inviting applications. The official announcement and full details were provided through the NIH grants site, and the listing includes NIH Office of Extramural Research (OER) webmaster contacts for technical issues accessing the announcement online.

In short, this FOA sought to fund a small number of well-organized PKD core centers that could serve as shared-resource engines for the PKD field, supporting both discovery and patient-oriented work and specifically strengthening the pipeline from basic PKD biology to clinical translation through centralized, high-value resources and coordinated research support.

Frequently Asked Questions (FAQs)

What is this grant opportunity?

This opportunity is the Polycystic Kidney Disease (PKD) Research and Translation Core Centers (P30) program, Funding Opportunity Number RFA-DK-09-007. It is an NIH grant program run by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

What is the main purpose of the PKD Research and Translation Core Centers (P30) program?

The purpose is to strengthen and accelerate PKD research by funding dedicated core centers that function as organized hubs. These hubs are meant to make PKD research more efficient by providing shared infrastructure, expertise, and services that multiple investigators can use.

What does the FOA mean by emphasizing "translation"?

The FOA emphasizes translation in the sense of helping discoveries about PKD biology move more smoothly from lab findings into tools, approaches, and evidence that can inform clinical practice.

What does "P30 Core Center mechanism" mean in this context?

The NIH P30 mechanism is designed to support shared resources rather than stand-alone research projects. Under this FOA, centers are expected to develop and operate core facilities, services, and other centralized resources used by multiple investigators.

Is this funding intended for stand-alone research projects?

No. The FOA describes the P30 Core Center mechanism as supporting shared resources and infrastructure rather than stand-alone research projects.

What types of activities or resources are these centers expected to provide?

Centers are expected to develop and operate core facilities, services, and other centralized resources. The FOA frames these as "shared institutional and national resources" that reduce duplication, standardize methods where helpful, and provide reliable access to specialized tools and support.

Who is supposed to use the center resources?

The centers are intended to support multiple investigators working on PKD, spanning both basic science and clinical research. The FOA also indicates the centers should contribute capabilities that benefit PKD research more broadly (beyond only the local institution).

Are these centers expected to serve only local investigators?

No. The FOA describes the resources as both institutional and national in scope, meaning centers are expected to serve their local research community and also contribute capabilities that benefit PKD research more broadly.

What overall impact is NIDDK aiming for with these core centers?

The stated overall goal is to raise the quality, coordination, and productivity of PKD research by improving access to specialized tools and support, reducing duplication, and standardizing methods where helpful, while strengthening the pipeline from basic PKD biology to clinical translation.

Which NIH institute is sponsoring or inviting applications?

The sponsoring agency is the National Institutes of Health (NIH), and the institute inviting applications is the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

What is the Funding Opportunity Number (FOA number)?

The Funding Opportunity Number is RFA-DK-09-007.

What grant mechanism is used?

This opportunity uses the NIH P30 Core Center mechanism.

What funding instrument type is this opportunity?

The opportunity uses the grant funding instrument.

How much total funding did NIDDK plan to commit, and for what time period?

NIDDK planned to commit up to $4.25 million in total funding in fiscal year 2010 for this program.

How many awards were expected?

The FOA indicated an expectation of making up to four new or competing awards.

What is the listed award ceiling?

The listed award ceiling is $750,000.

Is cost sharing or matching required?

No. The FOA states there is no cost sharing or matching requirement as a condition of award under this announcement.

What is the CFDA number associated with this opportunity?

The opportunity is associated with CFDA number 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research).

Is this a discretionary funding opportunity?

Yes. The opportunity is categorized as discretionary.

Which organizations are eligible to apply?

Eligibility is broad and includes public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (with small businesses also listed separately as eligible), and many types of government entities (state, county, city/township, special district governments, independent school districts, and public housing/Indian housing authorities).

Are tribal governments and tribal organizations eligible?

Yes. The eligibility description includes federally recognized tribal governments and other tribal entities, as well as tribal organizations.

Are U.S. territories or possessions eligible?

Yes. The eligibility section includes U.S. territories or possessions, and also references regional organizations.

Are community-serving and minority-serving institutions included in eligibility?

Yes. The eligibility section explicitly calls out institution types and community-serving categories including Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations.

Are non-U.S. (foreign) organizations eligible to apply?

Yes. The FOA indicates that non-domestic (non-U.S.) entities or foreign organizations are eligible.

Can federal agencies apply?

Yes. The FOA indicates that eligible agencies of the federal government may apply.

When was this opportunity posted and created?

The opportunity was posted on December 22, 2009, and created on December 23, 2009.

What was the application deadline?

The original and current application closing date listed is March 10, 2010.

When was the opportunity archived?

The archive date listed is April 10, 2010.

Where were the official announcement and full details provided?

The FOA indicates the official announcement and full details were provided through the NIH grants site.

Who is listed for technical issues accessing the announcement online?

The listing notes NIH Office of Extramural Research (OER) webmaster contacts for technical issues accessing the announcement online.

What kinds of PKD research does this program aim to support?

The program aims to support investigators working on both basic science and clinical research in PKD, with a specific emphasis on enabling translation from PKD biology discoveries toward clinically relevant tools, approaches, and evidence.

What is the basic strategy for making PKD research more efficient under this FOA?

The strategy described is to fund organized core centers that provide shared infrastructure and services, reduce duplication across labs or studies, standardize methods where helpful, and offer reliable access to specialized tools and support that would be difficult to maintain within individual labs or single clinical studies.

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