Opportunity Information: Apply for PA 16 147
Apply for PA 16 147
- The HHS-NIH11 in the education, health sector is offering a public funding opportunity titled "Population Health Interventions: Integrating Individual and Group Level Evidence (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121, 93.273, 93.279, 93.399,.
- This funding opportunity was created on Mar 22, 2016 and posted on Mar 22, 2016.
- Applicants must submit their applications by May 07, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
The Population Health Interventions: Integrating Individual and Group Level Evidence (R21) grant opportunity (Funding Opportunity Number PA 16-147) is a discretionary NIH funding announcement focused on moving health research beyond strictly biological and clinical settings and into real-world population contexts. The central idea is that improving health outcomes and reducing disease burden often requires intervening not only at the level of individuals, but also at the level of groups, communities, systems, and environments. This opportunity is designed to support research projects that bring together multiple disciplines to develop and test population health interventions that address the social, economic, and environmental conditions that shape health, rather than only treating downstream symptoms or individual behaviors in isolation.
The announcement emphasizes multilevel and transdisciplinary intervention research. In practice, that means proposing interventions that operate across more than one level of influence (for example, combining individual-level strategies with changes in organizational practices, community resources, built environments, or policy-related conditions). It also means teams are expected to integrate perspectives and methods across fields, reflecting how complex population health problems tend to be. The framing signals interest in work that explicitly connects evidence from individual-level studies with group-level or structural evidence, and then uses that integrated evidence base to design interventions that can produce measurable improvements in health outcomes at scale.
This is an NIH grant mechanism using the R21 funding instrument, which is commonly used for exploratory or early-stage research. The listed award ceiling is $200,000, indicating a relatively modest budget intended to enable pilot testing, proof-of-concept studies, or the development and initial evaluation of innovative intervention approaches that could later be expanded through larger mechanisms. The activity categories are listed as Education and Health, and the CFDA program numbers associated with the announcement include 93.121, 93.273, 93.279, and 93.399, reflecting that multiple NIH program areas may align with the topic.
Eligibility is broad and includes many types of domestic organizations. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations other than federally recognized tribal governments; public housing authorities and Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (as long as they are not institutions of higher education, in the categories specified); for-profit organizations other than small businesses; and small businesses. The listing also includes an “Others” category with a note to consult additional eligibility details in the full announcement, which usually covers any special conditions or clarifications NIH wants applicants to be aware of.
The sponsoring agency is the U.S. Department of Health and Human Services, National Institutes of Health (listed as HHS-NIH11). The opportunity was posted on March 22, 2016 (with the same date shown as the creation date), and the closing date provided is May 7, 2019. While the dates indicate this specific posting cycle has closed, the summary remains useful as a description of NIH’s priorities in population health intervention research during that period and can help applicants anticipate what similar NIH population health FOAs tend to value: rigorous intervention design, attention to upstream determinants, and approaches that can plausibly influence health outcomes across communities or populations rather than only within clinical encounters.
Overall, this FOA is aimed at advancing actionable knowledge about how to improve population health by targeting the underlying conditions that shape risk and resilience, encouraging applicants to build interventions that reflect the reality that health is produced through interacting individual, social, economic, and environmental forces.
Frequently Asked Questions (FAQs)
What is the name of this grant opportunity?
The opportunity is titled Population Health Interventions: Integrating Individual and Group Level Evidence (R21).
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is PA 16-147.
Which agency sponsors this funding opportunity?
The sponsoring agency is the U.S. Department of Health and Human Services (HHS), National Institutes of Health (NIH), listed as HHS-NIH11.
What is the main purpose of this FOA?
This FOA focuses on advancing population health research by supporting interventions designed for real-world population contexts, not only biological or clinical settings. It emphasizes improving health outcomes and reducing disease burden by intervening at both the individual level and the group/community/system/environment level.
What kinds of problems or determinants does the FOA want applicants to address?
The FOA encourages interventions that address social, economic, and environmental conditions that shape health. The emphasis is on upstream determinants that influence risk and resilience, rather than only downstream symptoms or individual behaviors in isolation.
What does "integrating individual and group level evidence" mean in this announcement?
It refers to explicitly connecting evidence from individual-level studies with evidence at group, structural, community, organizational, environmental, or systems levels, and using that combined evidence base to design and test interventions intended to improve measurable health outcomes at scale.
What does the FOA mean by "multilevel" intervention research?
"Multilevel" means the proposed intervention operates across more than one level of influence. For example, combining an individual-focused component with changes to organizational practices, community resources, the built environment, or policy-related conditions.
What does the FOA mean by "transdisciplinary" research?
It means projects are expected to bring together multiple disciplines and integrate perspectives and methods across fields, reflecting the complexity of population health challenges.
What grant mechanism is used for this opportunity?
This funding opportunity uses the NIH R21 mechanism.
What does the R21 mechanism imply about the type of work expected?
The R21 mechanism is commonly used for exploratory or early-stage research. In this FOA, that aligns with enabling pilot testing, proof-of-concept work, and development/initial evaluation of innovative approaches that could later be expanded through larger funding mechanisms.
What is the budget ceiling for awards under this FOA?
The listed award ceiling is $200,000.
What are the activity categories associated with this opportunity?
The activity categories listed are Education and Health.
Which CFDA program numbers are associated with this FOA?
The CFDA program numbers associated with the announcement include 93.121, 93.273, 93.279, and 93.399.
Who is eligible to apply?
Eligibility is broad and includes many domestic organization types, including:
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Federally recognized Native American tribal governments
- Native American tribal organizations other than federally recognized tribal governments
- Public housing authorities and Indian housing authorities
- Nonprofit organizations with or without 501(c)(3) status (in the specified categories and not institutions of higher education)
- For-profit organizations other than small businesses
- Small businesses
Does the FOA mention any other eligibility category?
Yes. The listing includes an "Others" category with a note to consult additional eligibility details in the full announcement for any special conditions or clarifications.
When was this opportunity posted?
The opportunity was posted on March 22, 2016 (and the same date is shown as the creation date).
What was the closing date for this opportunity?
The closing date provided is May 7, 2019.
Is this opportunity still open?
Based on the provided dates, this specific posting cycle has closed (closing date: May 7, 2019).
If the cycle is closed, why is the summary still useful?
Even though the dates indicate the specific cycle has ended, the summary is useful as a description of NIH priorities in population health intervention research during that period. It can also help applicants anticipate what similar NIH population health FOAs tend to value, such as rigorous intervention design, attention to upstream determinants, and population-relevant approaches.
What kinds of interventions does this FOA prioritize?
The FOA prioritizes interventions that can plausibly improve health outcomes across communities or populations, rather than focusing only on clinical encounters or isolated individual behavior change.
What overall approach does the FOA encourage for improving population health?
It encourages building interventions that reflect how health is produced through interacting individual, social, economic, and environmental forces, with an emphasis on generating actionable knowledge about improving population health by targeting underlying conditions.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 16 147) also looked into and applied for these:
| Funding Opportunity |
|---|
| Role of Astrocytes and Astrocytic Networks in Drug Abuse (R21) Apply for PA 16 145 Funding Number: PA 16 145 Agency: HHS-NIH11 Category: Education, Health Funding Amount: $200,000 |
| Population Health Interventions: Integrating Individual and Group Level Evidence (R01) Apply for PA 16 146 Funding Number: PA 16 146 Agency: HHS-NIH11 Category: Education, Health Funding Amount: Case Dependent |
| Role of Astrocytes and Astrocytic Networks in Drug Abuse (R01) Apply for PA 16 144 Funding Number: PA 16 144 Agency: HHS-NIH11 Category: Education, Health Funding Amount: Case Dependent |
| Revision Applications to R01 Awards for Research on the NCI's Provocative Questions (R01) Apply for RFA CA 16 010 Funding Number: RFA CA 16 010 Agency: HHS-NIH11 Category: Education, Health Funding Amount: $150,000 |
| Revisions to Add Provocative Question-Relevant Research to Active Research Projects (P01) Apply for RFA CA 16 013 Funding Number: RFA CA 16 013 Agency: HHS-NIH11 Category: Education, Health Funding Amount: $150,000 |
| Revisions Applications to P50 Awards for Research on NCI's Provocative Questions (P50) Apply for RFA CA 16 012 Funding Number: RFA CA 16 012 Agency: HHS-NIH11 Category: Education, Health Funding Amount: $150,000 |
| Revision Applications to U01 Awards for Research on the NCI's Provocative Questions (U01) Apply for RFA CA 16 011 Funding Number: RFA CA 16 011 Agency: HHS-NIH11 Category: Education, Health Funding Amount: $150,000 |
| Integrating Biospecimen Science into Clinical Assay Development (U01) Apply for PAR 16 166 Funding Number: PAR 16 166 Agency: HHS-NIH11 Category: Education, Health Funding Amount: $250,000 |
| Novel Strategies for Targeting HIV-CNS Reservoirs without Reactivation (R01) Apply for RFA MH 17 101 Funding Number: RFA MH 17 101 Agency: HHS-NIH11 Category: Education, Health Funding Amount: Case Dependent |
| Novel Strategies for Targeting HIV-CNS Reservoirs without Reactivation (R21) Apply for RFA MH 17 100 Funding Number: RFA MH 17 100 Agency: HHS-NIH11 Category: Education, Health Funding Amount: $200,000 |
| Pilot and Feasibility Studies Evaluating the Role of RNA Modifications (the 'epitranscriptome') in Cancer Biology (R21) Apply for PA 16 177 Funding Number: PA 16 177 Agency: HHS-NIH11 Category: Education, Health Funding Amount: $200,000 |
| Exploratory Grants in Cancer Epidemiology and Genomics Research (R21) Apply for PA 16 175 Funding Number: PA 16 175 Agency: HHS-NIH11 Category: Education, Health Funding Amount: $200,000 |
| NCI Clinical and Translational Exploratory/Developmental Studies (R21) Apply for PAR 16 176 Funding Number: PAR 16 176 Agency: HHS-NIH11 Category: Education, Health Funding Amount: $200,000 |
| Improved Technologies and Ligands for Non-invasive Brain Imaging (R43/R44) Apply for RFA DA 17 011 Funding Number: RFA DA 17 011 Agency: HHS-NIH11 Category: Education, Health Funding Amount: Case Dependent |
| Improved Technologies and Ligands for Non-invasive Brain Imaging (R41/R42) Apply for RFA DA 17 010 Funding Number: RFA DA 17 010 Agency: HHS-NIH11 Category: Education, Health Funding Amount: Case Dependent |
| Paul Calabresi Career Development Award for Clinical Oncology (K12) Apply for PAR 16 189 Funding Number: PAR 16 189 Agency: HHS-NIH11 Category: Education, Health Funding Amount: Case Dependent |
| Tools for Cell Line Identification (R43/R44) Apply for PA 16 186 Funding Number: PA 16 186 Agency: HHS-NIH11 Category: Education, Health Funding Amount: Case Dependent |
| Laboratory and Diagnostic Tools to Advance Microbiome-Brain Research (R43/R44) Apply for RFA DA 17 017 Funding Number: RFA DA 17 017 Agency: HHS-NIH11 Category: Education, Health Funding Amount: $150,000 |
| Laboratory and Diagnostic Tools to Advance Microbiome-Brain Research (R41) Apply for RFA DA 17 016 Funding Number: RFA DA 17 016 Agency: HHS-NIH11 Category: Education, Health Funding Amount: $150,000 |
| Improving Smoking Cessation in Socioeconomically Disadvantaged Populations via Scalable Interventions (R01) Apply for PAR 16 202 Funding Number: PAR 16 202 Agency: HHS-NIH11 Category: Education, Health Funding Amount: Case Dependent |
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