Opportunity Information: Apply for W81XWH 09 MOMRP PTSDTX

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "Posttraumatic Stress Disorder (PTSD) Clinical Treatment Research Amoung Active Duty Army Soldiers" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on Jul 8, 2009 and posted on Jul 8, 2009.
  • Applicants must submit their applications by Nov 24, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $3,500,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $3,500,000.00 in funding.
  • The number of recipients for this funding is limited to 2 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for W81XWH 09 MOMRP PTSDTX

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Opportunity Summary:

This funding opportunity, titled "Posttraumatic Stress Disorder (PTSD) Clinical Treatment Research Among Active Duty Army Soldiers," was issued by the Department of the Army through the U.S. Army Medical Research Acquisition Activity (USAMRAA). It focuses on supporting clinical treatment research that can improve outcomes for active duty Army Soldiers experiencing deployment-related PTSD, particularly in the context of sustained wartime operational demands. The announcement frames the problem as urgent and system-wide: repeated deployments and a high operational tempo create ongoing physical and psychological strain that affects not only individual Soldier well-being, but also broader Army readiness, retention, and recruitment.

The need for improved treatment is grounded in prior military and scientific reporting cited in the announcement. It references findings suggesting that a substantial portion of active duty Soldiers screen positive for deployment-related PTSD after returning from Operation Iraqi Freedom or Operation Enduring Freedom, with estimates commonly cited around 17 percent and consistent with later Military Health Advisory Team assessments. The opportunity also stresses that PTSD rarely appears in isolation in this population. Instead, it is frequently complicated by co-occurring behavioral health issues such as depression, alcohol and other drug use, and suicide-related thoughts or behaviors. In practical terms, this means that many Soldiers may present with layered, overlapping clinical concerns that make straightforward treatment more difficult and increase risks to health and functioning.

A central point of the program announcement is that existing evidence-based PTSD treatments, while helpful for some, are not fully effective for many patients. The description specifically notes that commonly used interventions such as cognitive behavioral exposure-based therapies, Eye Movement Desensitization and Reprocessing (EMDR), and pharmacologic treatment with selective serotonin reuptake inhibitors (SSRIs) are only partially effective. It highlights the reality that treatment response can be limited and that some estimates suggest current evidence-based approaches may be ineffective for up to half of patients in terms of adequately reducing PTSD symptoms. The implication is that the Army is seeking research that can meaningfully improve clinical effectiveness, potentially by refining treatments, tailoring them to complex presentations, addressing comorbidities, improving engagement and adherence, or developing and testing new or enhanced clinical approaches suitable for active duty settings.

From an administrative and funding standpoint, this was a discretionary research and development opportunity in the science and technology category, offered under a cooperative agreement, grant, or procurement contract mechanism. The Funding Opportunity Number is W81XWH-09-MOMRP-PTSDTX, and the CFDA number listed is 12.420 (Military Medical Research and Development). The Army anticipated making about two awards, with an estimated total funding amount of $3,500,000 and a stated award ceiling of $3,500,000 (with no award floor specified). Cost sharing or matching was not required, and eligibility was described as unrestricted, meaning the competition was open to a wide range of applicant organizations unless further limited by details in the full announcement.

Key dates show the opportunity was posted July 8, 2009, originally due August 5, 2009, and later extended to a current closing date of November 24, 2009, with an archive date of December 24, 2009. For applicants needing assistance accessing the full announcement, the contact listed was Grants Officer Ethan J. Mueller at 301-619-2192. Overall, the grant call is best understood as a targeted push to strengthen the real-world clinical impact of PTSD treatment for active duty Soldiers by funding rigorous clinical treatment research that addresses the complexity and high stakes of PTSD in an operational military environment.

FAQs: Posttraumatic Stress Disorder (PTSD) Clinical Treatment Research Among Active Duty Army Soldiers

What is the title of this funding opportunity?

The funding opportunity is titled "Posttraumatic Stress Disorder (PTSD) Clinical Treatment Research Among Active Duty Army Soldiers."

Which agency issued this opportunity?

This opportunity was issued by the Department of the Army through the U.S. Army Medical Research Acquisition Activity (USAMRAA).

What is the main purpose of this grant opportunity?

The purpose is to support clinical treatment research intended to improve outcomes for active duty Army Soldiers experiencing deployment-related PTSD, particularly under sustained wartime operational demands.

Why does the announcement describe this need as urgent?

The announcement frames PTSD in the active duty force as a system-wide and urgent problem because repeated deployments and high operational tempo can create ongoing physical and psychological strain. This strain affects individual Soldier well-being and can also impact Army readiness, retention, and recruitment.

Who is the target population for the research?

The focus is on active duty Army Soldiers with deployment-related PTSD, including those returning from operational environments such as Operation Iraqi Freedom and Operation Enduring Freedom, as referenced in the announcement.

What does the announcement cite about how common deployment-related PTSD is among active duty Soldiers?

The announcement references prior reporting indicating that a substantial portion of active duty Soldiers screen positive for deployment-related PTSD after returning from Operation Iraqi Freedom or Operation Enduring Freedom, with estimates commonly cited around 17 percent and consistent with later Military Health Advisory Team assessments.

Does the announcement indicate PTSD often occurs with other conditions in this population?

Yes. The opportunity stresses that PTSD in active duty Soldiers frequently does not appear in isolation and is often complicated by co-occurring behavioral health issues such as depression, alcohol and other drug use, and suicide-related thoughts or behaviors.

Why do comorbid or co-occurring conditions matter for treatment research?

According to the announcement, layered and overlapping clinical concerns can make straightforward treatment more difficult and can increase risks to health and functioning. This adds complexity that treatment research may need to address to improve real-world outcomes.

What does the announcement say about current evidence-based PTSD treatments?

The announcement states that existing evidence-based PTSD treatments can be helpful for some patients but are not fully effective for many. It specifically notes that common interventions are only partially effective overall.

Which PTSD treatments are specifically mentioned as only partially effective?

The description mentions cognitive behavioral exposure-based therapies, Eye Movement Desensitization and Reprocessing (EMDR), and pharmacologic treatment with selective serotonin reuptake inhibitors (SSRIs).

How significant is the treatment effectiveness gap described in the announcement?

The announcement highlights that treatment response can be limited and cites estimates suggesting current evidence-based approaches may be ineffective for up to half of patients in terms of adequately reducing PTSD symptoms.

What kinds of research does the opportunity appear to encourage, based on the problem statement?

Based on the announcement language, the Army is seeking clinical treatment research that can meaningfully improve effectiveness in active duty settings. The description implies interest in work that could refine or tailor treatments for complex presentations, address comorbidities, improve engagement and adherence, or develop and test new or enhanced clinical approaches suitable for the active duty environment.

What is the Funding Opportunity Number?

The Funding Opportunity Number is W81XWH-09-MOMRP-PTSDTX.

What is the CFDA number associated with this opportunity?

The CFDA number listed is 12.420 (Military Medical Research and Development).

What type of funding opportunity is this described as?

It is described as a discretionary research and development opportunity in the science and technology category.

What award mechanisms are indicated in the announcement?

The opportunity was offered under a cooperative agreement, grant, or procurement contract mechanism.

How many awards did the Army anticipate making?

The Army anticipated making about two awards.

What is the estimated total funding amount?

The estimated total funding amount is $3,500,000.

What is the stated award ceiling?

The stated award ceiling is $3,500,000.

Is there an award floor specified?

No award floor is specified in the information provided.

Is cost sharing or matching required?

No. Cost sharing or matching was not required.

Who is eligible to apply?

Eligibility is described as unrestricted, meaning the competition was open to a wide range of applicant organizations unless further limited by details in the full announcement.

When was the opportunity posted?

The opportunity was posted on July 8, 2009.

What was the original application due date?

The original due date was August 5, 2009.

Was the due date extended?

Yes. The closing date was later extended to November 24, 2009.

What is the current closing date listed for the opportunity?

The current closing date listed is November 24, 2009.

When was the opportunity scheduled to be archived?

The archive date is listed as December 24, 2009.

Who is the point of contact for help accessing the full announcement?

The contact listed is Grants Officer Ethan J. Mueller.

What contact information is provided for the Grants Officer?

The phone number provided is 301-619-2192.

What is the overall goal of the Army in funding this research?

Overall, the call is framed as a targeted effort to strengthen the real-world clinical impact of PTSD treatment for active duty Soldiers by funding rigorous clinical treatment research that addresses the complexity and high stakes of PTSD in an operational military environment.

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