PPHF 2016: Increasing HPV Vaccine Coverage by Strengthening Adolescent AFIX Activities, Financed in Part by 2016 Prevention and Public Health Funds | Apply Online

Opportunity Summary:

The grant opportunity titled "PPHF 2016: Increasing HPV Vaccine Coverage by Strengthening Adolescent AFIX Activities, Financed in Part by 2016 Prevention and Public Health Funds" is a CDC-funded cooperative agreement designed to raise HPV vaccination rates among adolescents by expanding and strengthening the AFIX approach. AFIX, which stands for Assessment, Feedback, Incentives, and eXchange, is presented as a practical, research-informed quality improvement method that works directly at the immunization provider level. The core idea is that improving how clinics and health systems deliver vaccines, track patients, and follow up on missed opportunities can meaningfully increase vaccination coverage, especially for HPV, where adolescent uptake has historically lagged behind public health goals.

A central feature of AFIX is the in-person, face-to-face visit between trained AFIX staff and the provider’s clinical and administrative staff who influence immunization workflows. The funding notice emphasizes that this interaction is not just a data review; it is meant to be an active quality improvement intervention. During these sessions, AFIX staff assess a practice’s immunization performance, share targeted feedback, provide education and outreach, and work with the practice to build agreement around specific improvements. The expectation is that providers leave the visit with a clearer plan for strengthening immunization service delivery using concrete QI methods, rather than simply receiving a report card.

The rationale for investing in AFIX is grounded in evidence that assessment and feedback, especially when paired with other supports like incentives and peer exchange, can increase vaccination rates across many settings. The opportunity cites the Task Force on Community Preventive Services, which reaffirmed in 2008 that assessment and feedback are recommended based on strong evidence of effectiveness. It also points to CDC’s Advisory Committee on Immunization Practices (ACIP), which references this evidence in its general recommendations. In other words, the grant frames AFIX as a proven strategy that has enough research backing to justify scaling it up, particularly for adolescent vaccines like HPV.

The program’s focus is specifically on adolescent HPV vaccine coverage, described as "unacceptably low," and on the fact that adolescent-focused AFIX has been underused. The CDC highlights that this funding is meant to improve both the volume and the quality of AFIX visits. That means not only conducting more visits, but also ensuring those visits are performed according to the AFIX Policies and Procedures Guide and are strong enough to change provider behavior and clinic systems. The notice also references early or preliminary results from prior PPHF-funded HPV vaccination efforts and other recent AFIX activities, suggesting that HPV vaccination coverage can improve when AFIX is applied intentionally to adolescent vaccination practices.

Operationally, awardees are expected to target provider sites with low adolescent immunization coverage, prioritizing places where improvements could have the biggest effect. This can include large health networks or individual high-volume clinics that serve large adolescent populations, since reaching more patients per site can maximize impact. Recipients are encouraged to expand existing adolescent AFIX strategies already in use or to introduce new adolescent-focused approaches, as long as they align with AFIX standards. A major deliverable is increasing the number of adolescent AFIX visits that are actually implemented and completed, not just planned.

Accountability and evaluation are built into the grant through required reporting and data submission. The CDC expects recipients to provide information needed to evaluate both how AFIX is being carried out (process measures) and whether it is improving vaccination coverage (outcome measures). The notice mentions progress reports, online data reporting, and regular check-in calls as mechanisms for monitoring and supporting implementation. This evaluation requirement is framed as part of improving the overall AFIX strategy over time, not just documenting activity.

In terms of grant mechanics, the opportunity is listed as a discretionary award using a cooperative agreement structure, which typically means CDC involvement is more hands-on than in a standard grant. It is administered by HHS/CDC through the National Center for Immunization and Respiratory Diseases (NCIRD). The eligible applicants are governmental entities, specifically state governments, city or township governments, and special district governments. The funding opportunity number is CDC RFA IP16-1608PPHF16, and it is associated with CFDA 93.733. The posting and creation date are May 2, 2016, with an application closing date of June 4, 2016. The award ceiling is listed at $500,000, with an expected 20 awards, indicating an effort to support multiple jurisdictions in scaling up adolescent AFIX work to move closer to targets such as Healthy People 2020 and relevant HEDIS immunization performance measures.

Browse more opportunities from the same agency: HHS-CDC-NCIRD

Browse more opportunities from the same category: Health

Next opportunity: Medical Professionals Recruitment and Continuing Education Program

Previous opportunity: Geophysical Sub-surface Surveys

USGrants.org Applicant Portal:

Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.

Apply for CDC RFA IP16 1608PPHF16

 

[Watch] how do funding administrators access proposals?

Applicants also applied for:

Applicants who have applied for this opportunity (CDC RFA IP16 1608PPHF16) also looked into and applied for these:

 

Grant application guides and resources

It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!

Apply for Grants

 

 

Premium leads for funding administrators, grant writers, and loan issuers

Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.

If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.

Subscribe to Leads

 

Request more information:

Would you like to learn more about this funding opportunity, similar opportunities to "CDC RFA IP16 1608PPHF16", eligibility, application service, and/or application tips? Submit an inquiry below:

Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.