Opportunity Information: Apply for PAR 09 091
Apply for PAR 09 091
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Pre Application for Dietary Supplement Research Centers Botanicals (X02)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.213 Research and Training in Complementary and Integrative Health.
- This funding opportunity was created on Jan 29, 2009 and posted on Jan 29, 2009.
- Applicants must submit their applications by Apr 30, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: For profit organizations other than small businesses Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Native American tribal governments (Federally recognized) Small businesses Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education City or township governments Public and State controlled institutions of higher education Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts State governments Others (see text field entitled Additional Information on Eligibility for clarification).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Pre-Application for Dietary Supplement Research Centers - Botanicals (X02) opportunity (Funding Opportunity Number PAR 09 091) is an NIH-issued, discretionary grant mechanism designed as the required first step for organizations that want to compete for the full Botanical Research Center award under RFA OD 09 001 (Dietary Supplements Research Centers - Botanicals, P50). It is sponsored by the NIH Office of Dietary Supplements (ODS) along with the National Center for Complementary and Alternative Medicine (NCCAM, now known as NCCIH) and the National Cancer Institute (NCI). In practical terms, this X02 solicitation is not the main center award itself; it is a pre-application screening process that NIH uses to identify the most competitive proposed botanical research centers before inviting a smaller set of applicants to submit the more extensive P50 application package.
The central purpose of the program is to encourage collaborative, interdisciplinary botanical research focused on botanicals that are relevant to dietary supplements. The emphasis is on basic and preclinical science that could plausibly contribute to health maintenance and/or the primary prevention of disease. This means applicants are expected to propose research that improves understanding of botanicals, their composition, biological activity, mechanisms, and other foundational or translationally relevant questions that support responsible use of dietary supplement botanicals. At the same time, the announcement is explicit about what it does not want to fund: the initiative is intended to advance the spectrum of botanical research activities, but it is not meant to support drug discovery. So, while rigorous scientific work on botanicals is encouraged, the center concept is not aimed at turning botanicals into pharmaceutical drug candidates or running a classic drug-development pipeline.
A key feature of this FOA is that submission of an X02 pre-application is mandatory for any institution seeking to apply to the companion P50 center funding opportunity (RFA OD 09 001). That requirement applies both to new applicants and to institutions that already have currently funded botanical research centers and want to compete again. After submission, the X02 pre-applications are reviewed by a group of external reviewers. Only those applicants judged to be the most outstanding are notified and invited to submit a full P50 application. In other words, the X02 functions as a gatekeeper: it reduces the burden on both applicants and reviewers by ensuring that only the strongest center concepts move forward into the full, resource-intensive P50 competition.
From an administrative standpoint, this is categorized as a grant under the NIH, with the funding activity aligned to health and listed under CFDA 93.213 (Research and Training in Complementary and Integrative Health). The opportunity does not require cost sharing or matching. The posting and creation date were January 29, 2009, with an original and current closing date of April 30, 2009, and an archive date of May 31, 2009, indicating this specific announcement cycle is historical rather than currently open.
Eligibility is broad and includes many organizational types, reflecting NIH norms for research center competitions. Eligible applicants include for-profit organizations (other than small businesses are explicitly listed, and small businesses are also listed), nonprofit organizations with and without 501(c)(3) status, public and private institutions of higher education, and a range of governmental entities such as state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities or Indian housing authorities. The eligibility language also includes tribal governments and tribal organizations, including federally recognized tribes and other tribal entities, as well as U.S. territories or possessions and regional organizations. The FOA further highlights categories such as Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs), and it notes that faith-based and community-based organizations and eligible federal agencies may apply as well, subject to the additional eligibility details referenced in the full announcement.
Operationally, interested applicants were directed to the NIH funding announcement page for full details and instructions. For access or technical issues, the contact provided is the NIH Office of Extramural Research (OER) Webmaster (FBOWebmaster@OD.NIH.GOV), which is a standard support route when applicants have trouble reaching the electronic FOA or related links. Overall, the opportunity is best understood as a formal NIH pre-proposal step for establishing or renewing a multidisciplinary botanical research center focused on dietary supplement-relevant botanicals, with a strong preference for foundational and preclinical work that supports prevention and health maintenance rather than drug discovery.
FAQs: Pre-Application for Dietary Supplement Research Centers - Botanicals (X02) (PAR 09 091)
What is the PAR 09 091 opportunity?
PAR 09 091 is an NIH-issued, discretionary grant opportunity for an X02 pre-application titled "Pre-Application for Dietary Supplement Research Centers - Botanicals (X02)." It is designed as a required first step for organizations that want to compete for the full Botanical Research Center award under the companion funding opportunity RFA OD 09 001 (P50).
Is this the main Botanical Research Center award?
No. This X02 solicitation is not the main center award. It is a pre-application screening process NIH uses to identify the most competitive proposed botanical research centers before inviting selected applicants to submit the full P50 application package under RFA OD 09 001.
Why does NIH require an X02 pre-application?
The X02 pre-application functions as a gatekeeper. NIH uses it to reduce burden on applicants and reviewers by ensuring that only the strongest center concepts move forward into the full, resource-intensive P50 competition.
Is submission of the X02 pre-application mandatory to apply for the P50?
Yes. Submission of an X02 pre-application is mandatory for any institution seeking to apply to the companion P50 center funding opportunity (RFA OD 09 001).
Do currently funded botanical research centers have to submit an X02 to compete again?
Yes. The requirement applies both to new applicants and to institutions that already have currently funded botanical research centers and want to compete again.
Who sponsors this opportunity within NIH?
The opportunity is sponsored by the NIH Office of Dietary Supplements (ODS) along with the National Center for Complementary and Alternative Medicine (NCCAM, now known as NCCIH) and the National Cancer Institute (NCI).
What is the main purpose of the program?
The central purpose is to encourage collaborative, interdisciplinary botanical research focused on botanicals that are relevant to dietary supplements.
What types of research does the announcement emphasize?
The emphasis is on basic and preclinical science that could plausibly contribute to health maintenance and/or the primary prevention of disease, including work that improves understanding of botanicals, their composition, biological activity, mechanisms, and other foundational or translationally relevant questions supporting responsible use of dietary supplement botanicals.
Is drug discovery an intended focus of this initiative?
No. The announcement explicitly notes that while it is intended to advance botanical research activities, it is not meant to support drug discovery. The center concept is not aimed at turning botanicals into pharmaceutical drug candidates or running a classic drug-development pipeline.
How are X02 pre-applications handled after submission?
X02 pre-applications are reviewed by a group of external reviewers. Only applicants judged to be the most outstanding are notified and invited to submit a full P50 application.
What happens if an organization is not invited to submit a P50 application?
Based on the process described, only those judged most outstanding are invited to submit the full P50 application. The information provided does not describe an alternative path within this cycle for those not invited.
What is the companion full application opportunity?
The companion opportunity is RFA OD 09 001, titled "Dietary Supplements Research Centers - Botanicals (P50)." The X02 pre-application under PAR 09 091 is the required first step to compete for that P50 award.
What NIH/assistance listing is associated with this program?
The funding activity is aligned to health and is listed under CFDA 93.213 (Research and Training in Complementary and Integrative Health).
Does this opportunity require cost sharing or matching?
No. The opportunity does not require cost sharing or matching.
When was this opportunity posted, and what were the closing dates?
The posting and creation date were January 29, 2009. The original and current closing date were April 30, 2009. The archive date was May 31, 2009.
Is this funding opportunity currently open?
No. The closing and archive dates indicate this specific announcement cycle is historical rather than currently open.
Who is eligible to apply?
Eligibility is broad and includes many organizational types. Eligible applicants include for-profit organizations (including small businesses), nonprofit organizations with and without 501(c)(3) status, public and private institutions of higher education, and governmental entities such as state, county, city or township, special district governments, independent school districts, and public housing authorities or Indian housing authorities.
Are tribal governments and tribal organizations eligible?
Yes. The eligibility language includes tribal governments and tribal organizations, including federally recognized tribes and other tribal entities.
Are U.S. territories or regional organizations included in eligibility?
Yes. The eligibility language includes U.S. territories or possessions and regional organizations.
Does the FOA highlight any institution categories in particular?
Yes. It highlights categories such as Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).
Can faith-based or community-based organizations apply?
Yes. The FOA notes that faith-based and community-based organizations may apply, subject to the additional eligibility details referenced in the full announcement.
Can federal agencies apply?
Yes. The FOA notes that eligible federal agencies may apply, subject to the additional eligibility details referenced in the full announcement.
Where were applicants directed for full details and instructions?
Interested applicants were directed to the NIH funding announcement page for full details and instructions.
Who should be contacted for access or technical issues related to the announcement?
For access or technical issues, the contact provided is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
In one sentence, how should this opportunity be understood?
It is a formal NIH pre-proposal step for establishing or renewing a multidisciplinary botanical research center focused on dietary supplement-relevant botanicals, emphasizing foundational and preclinical work supporting prevention and health maintenance rather than drug discovery.
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