Opportunity Information: Apply for PAR 10 287
Apply for PAR 10 287
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Pre Application for the 2011 NIDA Avant Garde Award Program for HIV/AIDS Research (X02)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Sep 23, 2010 and posted on Sep 23, 2010.
- Applicants must submit their applications by Feb 11, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Public housing authorities/Indian housing authorities Private institutions of higher education Public and State controlled institutions of higher education State governments Native American tribal organizations (other than Federally recognized tribal governments) Special district governments Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments City or township governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Pre-Application for the 2011 NIDA Avant Garde Award Program for HIV/AIDS Research (X02) (Funding Opportunity Number PAR 10-287) is a National Institutes of Health opportunity created by the National Institute on Drug Abuse (NIDA) to identify exceptionally creative scientists with bold, high-impact ideas for HIV/AIDS research in the context of drug abuse. The program is designed to complement NIDA's standard investigator-initiated grants by deliberately making room for projects that are unusually innovative, potentially transformative, and not a great fit for traditional grant mechanisms. In practical terms, NIDA is looking for research concepts that could open up entirely new avenues for HIV prevention and treatment among people who use drugs, rather than incremental extensions of existing lines of work.
A central expectation is that the proposed project truly embodies the "avant garde" idea: the science should be substantially different from what the applicant or others are already doing. The emphasis is on originality and the likelihood of changing the field, such as introducing new conceptual frameworks, methods, or intervention approaches that could reshape how HIV/AIDS is addressed in drug-using populations. Another key requirement is that the topic area must align with priorities laid out in the Trans-NIH Plan for HIV-Related Research (FY2011), meaning proposals need to fit within the broader NIH HIV research strategy rather than being disconnected from federal research priorities.
This announcement covers only the first stage of a two-phase competition. The X02 mechanism is used strictly for pre-applications, functioning as an initial screening step. These pre-applications are reviewed by external reviewers, who select the most outstanding submissions, focusing on applicants who demonstrate exceptional creativity and who propose highly significant, innovative projects that may not be appropriate for standard grant pathways. If a pre-application is judged to be among the strongest, the investigator will be invited to submit a full application under a separate funding announcement, RFA-DA-11-002. Importantly, no funding decisions or awards are made under the X02 pre-application announcement itself; it is only a gateway to the full application process where awards are actually issued.
The opportunity is categorized as a discretionary grant within the health and education activity area and is associated with CFDA 93.279 (Drug Abuse and Addiction Research Programs). It does not require cost sharing or matching funds, which lowers the financial barrier for institutions and applicants.
Eligibility is broad and includes many types of organizations that could host and support an investigator, such as public and private institutions of higher education, nonprofit organizations (including both 501(c)(3) and non-501(c)(3) entities outside higher education), for-profit organizations other than small businesses, small businesses, state and local governments (including counties, cities/townships, special districts, and independent school districts), public housing authorities/Indian housing authorities, and tribal governments and organizations (both federally recognized and other tribal entities). The eligibility language also specifically calls out a variety of institution types and community-oriented organizations, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities (TCCUs), faith-based and community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal agencies. This breadth reflects that NIDA is prioritizing the investigator and the quality of the idea, while allowing many organizational homes capable of administering NIH grants.
Timing-wise, the announcement was posted and created on September 23, 2010, with an original and current closing date of February 11, 2011, and an archive date of March 14, 2011. Applicants who wanted to compete for the 2011 Avant Garde Award needed to submit by the February deadline to be considered for invitation to the full RFA.
For applicants trying to understand fit and expectations, NIH pointed to an FAQ resource hosted by NIDA, and to the full announcement page in the NIH Grants Guide for complete instructions and requirements. For technical issues accessing the announcement online, NIH provided contact support through the NIH Office of Extramural Research (OER) Webmaster email.
FAQs: 2011 NIDA Avant Garde Award Program for HIV/AIDS Research (X02) Pre-Application (PAR 10-287)
What is this funding opportunity?
This opportunity is the pre-application stage for the 2011 NIDA Avant Garde Award Program for HIV/AIDS Research (X02), Funding Opportunity Number PAR 10-287. It is a National Institutes of Health (NIH) opportunity created by the National Institute on Drug Abuse (NIDA) to identify exceptionally creative scientists with bold, high-impact ideas for HIV/AIDS research in the context of drug abuse.
Who is the sponsoring agency?
The sponsoring agency is the National Institutes of Health (NIH), and the specific institute running the program is the National Institute on Drug Abuse (NIDA).
What is the goal of the NIDA Avant Garde Award program?
The program aims to surface unusually innovative, potentially transformative HIV/AIDS research concepts that could open entirely new avenues for HIV prevention and treatment among people who use drugs, rather than incremental extensions of existing work.
How is this program different from standard NIH investigator-initiated grants?
This program is designed to complement NIDA's standard investigator-initiated grants by deliberately making room for projects that are highly innovative and potentially transformative, especially when the ideas are not a great fit for traditional grant mechanisms.
What does NIDA mean by "avant garde" in this announcement?
"Avant garde" refers to research that is substantially different from what the applicant or others are already doing, with an emphasis on originality and a strong likelihood of changing the field. Examples of the kinds of advances highlighted include new conceptual frameworks, new methods, or new intervention approaches that could reshape how HIV/AIDS is addressed in drug-using populations.
What scientific focus areas are expected?
The research focus is HIV/AIDS research in the context of drug abuse, particularly concepts that could lead to new directions for HIV prevention and treatment among people who use drugs.
Do proposals need to align with any NIH-wide priorities?
Yes. A key requirement is that the topic aligns with priorities in the Trans-NIH Plan for HIV-Related Research (FY2011). Proposals are expected to fit within the broader NIH HIV research strategy.
Is this announcement for a full grant application?
No. This announcement covers only the first stage of a two-phase competition. It uses the X02 mechanism strictly for pre-applications and serves as an initial screening step.
What is the X02 mechanism used for here?
In this program, the X02 mechanism is used only for pre-applications. It functions as a gateway step to identify the strongest, most creative and high-impact concepts before inviting selected investigators to submit a full application.
Will any awards or funding be made under PAR 10-287 (X02)?
No. No funding decisions or awards are made under the X02 pre-application announcement itself. Funding decisions and awards occur only in the later stage after submission of a full application under a separate funding announcement.
What happens if a pre-application is selected as one of the strongest submissions?
If the pre-application is judged among the strongest, the investigator will be invited to submit a full application under a separate funding announcement: RFA-DA-11-002.
Who reviews the pre-applications?
Pre-applications are reviewed by external reviewers who select the most outstanding submissions.
What criteria are emphasized in the pre-application review?
Reviewers focus on identifying exceptionally creative scientists and highly significant, innovative projects, especially those that may not be appropriate for standard grant pathways.
What type of funding category is this opportunity?
The opportunity is categorized as a discretionary grant in the health and education activity area.
What CFDA number is associated with this opportunity?
The opportunity is associated with CFDA 93.279 (Drug Abuse and Addiction Research Programs).
Is cost sharing or matching required?
No. The announcement states that it does not require cost sharing or matching funds.
Who is eligible to apply (organizational eligibility)?
Eligibility is broad and includes many organization types that can host and support an investigator, including:
- Public and private institutions of higher education
- Nonprofit organizations (both 501(c)(3) and non-501(c)(3), excluding higher education where applicable)
- For-profit organizations other than small businesses
- Small businesses
- State governments
- Local governments (including counties, cities/townships, special districts, and independent school districts)
- Public housing authorities/Indian housing authorities
- Tribal governments and organizations (federally recognized and other tribal entities)
- U.S. territories or possessions
- Eligible federal agencies
Are minority-serving institutions and community-based organizations included in eligibility?
Yes. The eligibility language specifically calls out Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and tribally controlled colleges and universities (TCCUs). It also specifically includes faith-based and community-based organizations and regional organizations.
When was this funding opportunity posted?
The announcement was posted and created on September 23, 2010.
What was the application deadline for the pre-application?
The original and current closing date listed for the pre-application was February 11, 2011.
When was the opportunity archived?
The archive date was March 14, 2011.
Where can applicants find additional official guidance or FAQs from NIDA?
NIH pointed applicants to an FAQ resource hosted by NIDA and to the full announcement page in the NIH Grants Guide for complete instructions and requirements.
Who should be contacted for technical problems accessing the announcement online?
For technical issues accessing the announcement online, NIH provided contact support through the NIH Office of Extramural Research (OER) Webmaster email.
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| Substance Use and Abuse, Risky Decision Making and HIV/AIDS (R03) Apply for PA 11 008 Funding Number: PA 11 008 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Substance Use and Abuse, Risky Decision Making and HIV/AIDS (R01) Apply for PA 11 006 Funding Number: PA 11 006 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Substance Use and Abuse, Risky Decision Making and HIV/AIDS (R21) Apply for PA 11 007 Funding Number: PA 11 007 Agency: National Institutes of Health Category: Education Health Funding Amount: $200,000 |
| HIV Infection of the Central Nervous System (R01) Apply for PA 11 014 Funding Number: PA 11 014 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| National Gene Vector Biorepository and Coordinating Center (P40) Apply for RFA RR 10 010 Funding Number: RFA RR 10 010 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Medical Marijuana Policy Research Exploring Trends and Impacts (R01) Apply for RFA DA 11 008 Funding Number: RFA DA 11 008 Agency: National Institutes of Health Category: Education Health Funding Amount: $500,000 |
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| The Development Of Frontal Cortex And Limbic System And Their Roles In Drug Abuse (R01) Apply for PA 11 027 Funding Number: PA 11 027 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Continued Development and Maintenance of Software (R01) Apply for PAR 11 028 Funding Number: PAR 11 028 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Statistical Coordination Center for the Population based Research Optimizing Screening through Personalized Regimens (PROSPR)(U01) Apply for RFA CA 11 004 Funding Number: RFA CA 11 004 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Population based Research Optimizing Screening through Personalized Regimens (PROSPR) (U54) Apply for RFA CA 11 003 Funding Number: RFA CA 11 003 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
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