Opportunity Information: Apply for PAR 12 164

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Pre Application for the FY13 NIDA Avant Garde Award Program for HIV/AIDS Research (X02)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs.
  • This funding opportunity was created on Apr 24, 2012 and posted on Apr 24, 2012.
  • Applicants must submit their applications by Oct 3, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $500,000.00 in funding.
  • Eligible applicants include: Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Special district governments Small businesses County governments Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments For profit organizations other than small businesses City or township governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Apply for PAR 12 164

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Opportunity Summary:

The Pre-Application for the FY13 NIDA Avant Garde Award Program for HIV/AIDS Research (X02) (Funding Opportunity Number PAR 12-164) is a National Institutes of Health (NIH) discretionary grant opportunity focused on supporting unusually creative, high-impact HIV/AIDS research tied to drug abuse. The central goal is to back individual scientists whose ideas are bold enough to open entirely new lines of HIV/AIDS research or create new pathways for preventing and treating HIV/AIDS specifically among people who use drugs. In this program, "avant garde" is not just a label for novelty; it signals a strong preference for proposals that are genuinely transformative and meaningfully different from what the applicant or the broader field is already doing. In other words, the program is meant to catalyze research that breaks from incremental advances and instead tests original concepts, unconventional methods, or new frameworks that could reshape how HIV/AIDS is understood and addressed in drug-using populations.

A key requirement is that the proposed research must align with priority areas described in the Trans-NIH Plan for HIV-Related Research maintained by the NIH Office of AIDS Research (linked in the announcement). This matters because it anchors highly innovative ideas to the federal HIV research strategy, ensuring that even unconventional projects connect to recognized national objectives. While the program emphasizes creative freedom and high-risk, high-reward thinking, it still expects applicants to situate their work within the broader HIV research agenda and to articulate how the work could plausibly lead to new prevention or treatment avenues relevant to drug abuse contexts.

Administratively, this posting describes a pre-application mechanism designated as X02, meaning it is positioned as an initial step rather than a full traditional research grant submission. The opportunity was posted on April 24, 2012, with an original and current closing date of October 3, 2012, and an archive date of November 3, 2012. The activity is categorized under Education and Health, and it falls under CFDA 93.279, Drug Abuse and Addiction Research Programs. No cost sharing or matching is required, which reduces barriers for applicants who may not have institutional resources to contribute mandatory matching funds.

The funding scale indicates a relatively selective, high-value program. The estimated total funding amount is $2,000,000, and the award ceiling is $500,000. This ceiling suggests that awards are intended to be substantial enough to let an investigator pursue a distinctive research direction, generate pivotal early findings, or build an initial platform for a new area of inquiry, while still being bounded to support a limited number of high-impact projects.

Eligibility is broad and includes many organizational types across the public, private, nonprofit, and educational sectors. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits with and without 501(c)(3) status, small businesses, and for-profit organizations other than small businesses. Government entities at multiple levels are also eligible, including state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities or Indian housing authorities. Tribal eligibility is explicitly included both for federally recognized Native American tribal governments and for tribal organizations and governments that are not federally recognized. The announcement further clarifies additional eligible groups such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities (TCCUs), regional organizations, faith-based or community-based organizations, and U.S. territories or possessions. Importantly, non-U.S. entities are eligible to apply, including foreign institutions, non-domestic components of U.S. organizations, and foreign components as allowed under the NIH Grants Policy Statement. This international openness signals an interest in recruiting the best ideas regardless of geography, especially given the global nature of HIV/AIDS and the cross-border relevance of drug use and related epidemics.

For applicants seeking the official announcement and full application instructions, the opportunity points to the NIH grants guide page for PAR 12-164 (the Additional Information Link). For technical issues accessing or linking to the announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV. Overall, the program is designed as a targeted investment in exceptional investigators with unusually original HIV/AIDS research concepts that could significantly alter prevention or treatment approaches for drug-abusing populations, while remaining aligned with the broader Trans-NIH HIV research strategy.

FAQs: FY13 NIDA Avant Garde Award Program for HIV/AIDS Research (X02) (PAR 12-164)

What is this funding opportunity?

This is the Pre-Application for the FY13 NIDA Avant Garde Award Program for HIV/AIDS Research (X02), Funding Opportunity Number PAR 12-164. It is a National Institutes of Health (NIH) discretionary grant opportunity focused on supporting unusually creative, high-impact HIV/AIDS research tied to drug abuse.

What is the main goal of the NIDA Avant Garde Award Program for HIV/AIDS Research?

The central goal is to support individual scientists with bold ideas that can open entirely new lines of HIV/AIDS research or create new pathways for preventing and treating HIV/AIDS specifically among people who use drugs.

What does "avant garde" mean in this program?

In this program, "avant garde" goes beyond novelty. It signals a strong preference for proposals that are genuinely transformative and meaningfully different from what the applicant or the broader field is already doing. The program is intended to catalyze research that breaks from incremental advances by testing original concepts, unconventional methods, or new frameworks that could reshape how HIV/AIDS is understood and addressed in drug-using populations.

Is this a full research grant application?

No. This posting describes a pre-application mechanism designated as X02, which is positioned as an initial step rather than a full traditional research grant submission.

What research focus is expected for proposals under this opportunity?

Proposals are expected to be high-impact HIV/AIDS research tied to drug abuse, with clear relevance to preventing or treating HIV/AIDS among people who use drugs. The emphasis is on high-risk, high-reward ideas that could plausibly lead to new prevention or treatment avenues in drug abuse contexts.

Does the proposed research need to align with any NIH-wide priorities or plans?

Yes. A key requirement is that the proposed research must align with priority areas described in the Trans-NIH Plan for HIV-Related Research maintained by the NIH Office of AIDS Research (as linked in the announcement). This anchors innovative projects to the federal HIV research strategy and recognized national objectives.

When was this opportunity posted and what are the key dates?

The opportunity was posted on April 24, 2012. The original and current closing date is October 3, 2012. The archive date is November 3, 2012.

What is the total estimated funding amount for this opportunity?

The estimated total funding amount is $2,000,000.

What is the award ceiling?

The award ceiling is $500,000.

Does this opportunity require cost sharing or matching funds?

No. No cost sharing or matching is required.

What category does this funding opportunity fall under?

The activity is categorized under Education and Health.

What is the CFDA number associated with this program?

This opportunity falls under CFDA 93.279, Drug Abuse and Addiction Research Programs.

Who is eligible to apply?

Eligibility is broad and includes many organizational types across the public, private, nonprofit, and educational sectors, as well as various government entities and tribal applicants. The announcement also explicitly includes a range of institution types such as minority-serving institutions and community-based organizations.

Are institutions of higher education eligible?

Yes. Eligible applicants include public and state-controlled institutions of higher education and private institutions of higher education.

Are nonprofit organizations eligible?

Yes. Eligible applicants include nonprofits with 501(c)(3) status and nonprofits without 501(c)(3) status.

Are businesses eligible?

Yes. Eligible applicants include small businesses and for-profit organizations other than small businesses.

Are government entities eligible to apply?

Yes. Government eligibility includes state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities or Indian housing authorities.

Are tribal governments and tribal organizations eligible?

Yes. Tribal eligibility is explicitly included for federally recognized Native American tribal governments and for tribal organizations and governments that are not federally recognized.

Are minority-serving institutions and other special organization types included in eligibility?

Yes. The announcement clarifies additional eligible groups such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities (TCCUs), regional organizations, faith-based or community-based organizations, and U.S. territories or possessions.

Are non-U.S. (foreign) organizations eligible to apply?

Yes. Non-U.S. entities are eligible to apply, including foreign institutions, non-domestic components of U.S. organizations, and foreign components as allowed under the NIH Grants Policy Statement.

Where can applicants find the official announcement and full instructions?

The opportunity directs applicants to the NIH grants guide page for PAR 12-164 (the Additional Information Link) for the official announcement and full application instructions.

Who should be contacted for technical issues accessing or linking to the announcement?

For technical issues accessing or linking to the announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

What kind of impact is NIH looking for through this program?

The program is designed to be a targeted investment in exceptional investigators with unusually original HIV/AIDS research concepts that could significantly alter prevention or treatment approaches for drug-abusing populations, while still remaining aligned with the broader Trans-NIH HIV research strategy.

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Advancing Exceptional Research on HIV/AIDS (R01) Apply for RFA DA 13 008

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Identifying Non coding RNA Targets for Early Detection of Cancer (R01) Apply for PA 12 213

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Identifying Non coding RNA Targets for Early Detection of Cancer (R21) Apply for PA 12 214

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Funding Number: PA 12 220
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Biomarkers for Early Detection of Hematopoietic Malignancies (R01) Apply for PA 12 221

Funding Number: PA 12 221
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Cohort Studies of HIV/AIDS and Substance Use (U01) Apply for PAR 12 222

Funding Number: PAR 12 222
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Advancing Community level Approaches to Reduce HIV Infection in Highly Impacted Communities (R01) Apply for RFA MH 13 090

Funding Number: RFA MH 13 090
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Advancing Community level Approaches to Reduce HIV Infection in Highly Impacted Communities (R21) Apply for RFA MH 13 091

Funding Number: RFA MH 13 091
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Advancing Community level Approaches to Reduce HIV Infection in Highly Impacted Communities (R34) Apply for RFA MH 13 092

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