Opportunity Information: Apply for W81XWH 11 PUPTH IIA

  • The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "Prehospital Use of Plasma for Traumatic Hemorrhage" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
  • This funding opportunity was created on May 4, 2011 and posted on May 4, 2011.
  • Applicants must submit their applications by Jul 29, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $16,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $8,000,000.00 in funding.
  • The number of recipients for this funding is limited to 3 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:

This funding opportunity, titled "Prehospital Use of Plasma for Traumatic Hemorrhage" (Funding Opportunity Number W81XWH 11 PUPTH IIA), is a US Department of the Army program announcement administered through the US Army Medical Research Acquisition Activity (USAMRAA) under the Combat Casualty Care Research Program (CCCRP). The work is managed through the Telemedicine and Advanced Technology Research Center (TATRC) at Fort Detrick, Maryland. The central aim is to support biotechnology-focused research and development that improves care for traumatic hemorrhage by advancing the evidence, tools, and practical capability to use plasma in the prehospital setting (meaning before a patient reaches a hospital, such as on ambulances, air medical transport, or battlefield evacuation platforms). Although the topic is rooted in combat casualty care priorities, the program explicitly expects the results to translate to civilian emergency medicine and trauma systems as well.

The opportunity is structured to encourage interdisciplinary partnerships, with an emphasis on industry-led teams that can also include academic institutions and government collaborators. The Army is looking for projects that do more than produce academic findings; they want research that culminates in outcomes and products that could plausibly transition into advanced development activities within the Department of Defense. In other words, proposals are expected to have a clear pathway from research to usable capability, such as validated protocols, field-ready concepts of operation, enabling devices, logistics approaches, or other practical deliverables that can be adopted by military medical systems. A stated program goal is to create enduring collaborations and initiatives that can support sustained business and enterprise solutions, reflecting a preference for approaches that can be operationalized and maintained rather than remaining one-off demonstrations.

From a funding and administrative standpoint, this is a discretionary award with the funding instrument listed as Cooperative Agreement/Grant, under the Science and Technology and other Research and Development category. The CFDA number is 12.420 (Military Medical Research and Development). The government anticipated making about three awards with an estimated total funding level of $16,000,000, and an award ceiling of $8,000,000 per project. There is no cost sharing or matching requirement stated. Eligibility is described as unrestricted, meaning proposals could come from a wide range of entity types, subject to any clarifications that may appear in the full announcement text.

The timeline in the source data shows the opportunity was posted on May 4, 2011, with an original and current closing date of July 29, 2011, and an archive date of August 28, 2011. That indicates it was a time-limited solicitation window from 2011, intended to rapidly stimulate progress on a specific trauma care priority area. A point of contact is listed for access issues with the full announcement: Mary Rico, Grants Officer, referencing W81XWH 11 PUPTH IAA.

In practical terms, the research topic area suggests interest in improving survival from severe bleeding by optimizing when and how plasma is given early, under the constraints of prehospital environments. Those constraints typically include limited storage options, temperature control challenges, short treatment windows, variable provider training levels, transport vibration and altitude, and the need for straightforward protocols that can be executed reliably. A strong application under this type of announcement would typically align clinical need, operational feasibility, and a development plan that moves toward fieldable solutions, while also contributing publishable knowledge that strengthens both military and civilian trauma care practices.

Frequently Asked Questions (FAQs): Prehospital Use of Plasma for Traumatic Hemorrhage (W81XWH 11 PUPTH IIA)

What is the title and focus of this funding opportunity?

The opportunity is titled "Prehospital Use of Plasma for Traumatic Hemorrhage" (Funding Opportunity Number W81XWH 11 PUPTH IIA). It supports biotechnology-focused research and development intended to improve care for traumatic hemorrhage by advancing the evidence, tools, and practical capability to use plasma in the prehospital setting (before a patient reaches a hospital).

Which US government organizations are associated with this program?

This is a US Department of the Army program announcement administered through the US Army Medical Research Acquisition Activity (USAMRAA) under the Combat Casualty Care Research Program (CCCRP). The work is managed through the Telemedicine and Advanced Technology Research Center (TATRC) at Fort Detrick, Maryland.

What does "prehospital" mean in the context of this program?

"Prehospital" refers to care delivered before arrival at a hospital. Examples mentioned include ambulances, air medical transport, and battlefield evacuation platforms.

Is this opportunity only for military/combat casualty care, or is civilian translation expected?

While the topic is rooted in combat casualty care priorities, the program explicitly expects results to translate to civilian emergency medicine and trauma systems as well.

What kinds of outcomes is the Army looking for beyond academic research?

The Army emphasizes projects that culminate in practical outcomes and products that could plausibly transition into advanced development activities within the Department of Defense. Examples described include validated protocols, field-ready concepts of operation, enabling devices, logistics approaches, or other practical deliverables that can be adopted by military medical systems.

Does the program encourage partnerships and team-based proposals?

Yes. The opportunity is structured to encourage interdisciplinary partnerships, with an emphasis on industry-led teams. These teams can also include academic institutions and government collaborators.

What is meant by a "clear pathway" from research to usable capability?

Based on the description, proposals are expected to show how the work will move from research into something operationally usable, such as protocols, concepts of operation, devices, or logistics approaches that can realistically be adopted and maintained by military medical systems and potentially applied in civilian trauma care settings.

Is the program interested in long-term or sustained solutions?

Yes. A stated program goal is to create enduring collaborations and initiatives that support sustained business and enterprise solutions, indicating a preference for approaches that can be operationalized and maintained rather than remaining one-off demonstrations.

What type of award instrument is anticipated?

The funding instrument is listed as a Cooperative Agreement/Grant, and it is described as a discretionary award in the Science and Technology and other Research and Development category.

What is the CFDA number for this program?

The CFDA number provided is 12.420 (Military Medical Research and Development).

How much total funding was anticipated, and how many awards were expected?

The government anticipated making about three awards with an estimated total funding level of $16,000,000.

What is the maximum (ceiling) amount per award?

The award ceiling is listed as $8,000,000 per project.

Is cost sharing or matching required?

No cost sharing or matching requirement is stated in the provided information.

Who is eligible to apply?

Eligibility is described as unrestricted, meaning proposals could come from a wide range of entity types, subject to any clarifications that may appear in the full announcement text.

When was the opportunity posted, and what were the close and archive dates?

The opportunity was posted on May 4, 2011. The original and current closing date is July 29, 2011, and the archive date is August 28, 2011.

Does the timeline indicate this was a limited-time solicitation?

Yes. The posted, closing, and archive dates indicate a time-limited solicitation window from 2011.

What topic challenges in the prehospital environment does the program description highlight?

The description notes that prehospital constraints typically include limited storage options, temperature control challenges, short treatment windows, variable provider training levels, transport vibration and altitude, and the need for straightforward protocols that can be executed reliably.

What kinds of platforms or settings are relevant for solutions under this program?

Solutions are relevant to prehospital platforms and settings described in the opportunity, including ground ambulances, air medical transport, and battlefield evacuation platforms.

What kind of application would align well with the intent of the announcement?

Based on the description, a strong application would align clinical need, operational feasibility, and a development plan that moves toward fieldable solutions, while also contributing knowledge that strengthens both military and civilian trauma care practices.

Who is the listed point of contact, and what are they noted for?

A point of contact is listed for access issues with the full announcement: Mary Rico, Grants Officer, referencing W81XWH 11 PUPTH IAA.

What is the administering office mentioned for acquisition and awards?

The program announcement is administered through USAMRAA (US Army Medical Research Acquisition Activity).

What is the managing organization and location mentioned for the work?

The work is managed through TATRC (Telemedicine and Advanced Technology Research Center) at Fort Detrick, Maryland.

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